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Search Results: 1 - 10 of 3021 matches for " Francesca Boscaro "
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A Proteomic Investigation of Soluble Olfactory Proteins in Anopheles gambiae
Guido Mastrobuoni, Huili Qiao, Immacolata Iovinella, Simona Sagona, Alberto Niccolini, Francesca Boscaro, Beniamino Caputo, Marta R. Orejuela, Alessandra della Torre, Stefan Kempa, Antonio Felicioli, Paolo Pelosi, Gloriano Moneti, Francesca Romana Dani
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0075162
Abstract: Odorant-binding proteins (OBPs) and chemosensory proteins (CSPs) are small soluble polypeptides that bind semiochemicals in the lymph of insect chemosensilla. In the genome of Anopheles gambiae, 66 genes encode OBPs and 8 encode CSPs. Here we monitored their expression through classical proteomics (2D gel-MS analysis) and a shotgun approach. The latter method proved much more sensitive and therefore more suitable for tiny biological samples as mosquitoes antennae and eggs. Females express a larger number and higher quantities of OBPs in their antennae than males (24 vs 19). OBP9 is the most abundant in the antennae of both sexes, as well as in larvae, pupae and eggs. Of the 8 CSPs, 4 were detected in antennae, while SAP3 was the only one expressed in larvae. Our proteomic results are in fairly good agreement with data of RNA expression reported in the literature, except for OBP4 and OBP5, that we could not identify in our analysis, nor could we detect in Western Blot experiments. The relatively limited number of soluble olfactory proteins expressed at relatively high levels in mosquitoes makes further studies on the coding of chemical messages at the OBP level more accessible, providing for few specific targets. Identification of such proteins in Anopheles gambiae might facilitate future studies on host finding behavior in this important disease vector.
The Use of Materials from Biomass as Construction Materials  [PDF]
Francesca Giglio
Open Journal of Civil Engineering (OJCE) , 2013, DOI: 10.4236/ojce.2013.32A009

The paper describes some studies conducted by the author, about low impact materials and, particularly, on alternative uses of biomass materials for building materials. Italy needs to develop renewable energy sources and agriculture offers many opportunities: biomass, vegetable residues for livestock breeding, food industry waste, organic waste, solid biofuels, biogas, and biofuels, will be the new renewable energy sources. Researches for promoting sustainable development, including chemistry field are increasing interest in the exploitation of vegetal biomass, in particular waste as a raw material for production of bio-products and biofuels. Not always, however, the use of waste materials such as biomass is the most appropriate, or in any case, the one with less energy expenditure. As ever more evident, in fact, the construction sector is approaching the possibility of using these materials for other purposes, combining the demands of saving natural resources, the need for energy efficiency in buildings and production processes.

Public Private Partnerships for Transportation Infrastructure Delivery  [PDF]
Francesca Leccis
Open Journal of Social Sciences (JSS) , 2015, DOI: 10.4236/jss.2015.35004

The term Public Private Partnerships includes different forms of collaboration between the public and the private sector. These formulas are adopted in a constantly increasing number of countries all over the world in order to overcome the chronic lack of funding and ensure the delivery of infrastructure projects. The paper illustrates the vital role of cooperation between public bodies and private entities in the delivery of public transportation infrastructure. In particular, it focuses on toll roads and highways. Key factors of success and risk are identified and illustrated through five case studies from Chile, Hungary, South Africa-Mozambique, United Kingdom and California.

Identity in Sport Teams  [PDF]
Cristina Zucchermaglio, Francesca Alby
Psychology (PSYCH) , 2011, DOI: 10.4236/psych.2011.23031
Abstract: In this paper we analyze identity in a soccer team using a discursive perspective, in which individual psycho-logical functioning is considered to be built in and through social interactions within groups. Analysis is based on naturally-occurring interactions that were audio recorded during technical meetings before and after the match. The data were collected within an ethnographic investigation of an Italian soccer tam carried out over a two-month period. The results show that the team’s members made rhetorical use of a complex repertoire of their own and others’ social identities, and that two main variables influenced the use of social identity markers: a) the role of the speakers (in particular the “power” role of the coach); b) the result of the match around which the interactive discourse revolved. Against this background, we discuss how narratives and identity positionings were used to achieve specific goals and to perform specific actions, such as the planning of future matches and the interpretation of victories and defeats.
Students’ Metaphors for Defining Their Learning Experience with Audio-Visible versus Invisible Authors. Results from a Case Study in a Social Science Discipline  [PDF]
Terry Inglese, Francesca Rigotti
Creative Education (CE) , 2011, DOI: 10.4236/ce.2011.23025
Abstract: This article summarizes an instructional experience designed and conducted at the University of Lugano – Communication Sciences – (Switzerland) within a Political Theory’s freshmen course, which involved disciplines like: philosophy, political science and epistemology. We offered students two types of authors to be learned: one through a multimedia video interview in combination with written texts of these authors, defined as the audio-visible authors, and one type of author offered only through a text-based format (the invisible author). We gathered quantitative data (students’ performance on their written exam compositions, their grades; the number of written words they wrote; and the number of times students mentioned the two types of authors in their written compositions). We also collected qualitative data (through semi-structured interviews and thinking aloud protocols), analyzing the metaphors students used to define the reading and learning experience with the audio-visible and the invisible authors. Results show that students perform better when the author to be studied is offered with more media instructional supports, they tend to establish a social relationship with the author, and the quality of their critical thinking and the level of interest in a new subject both increase. The article is divided in three parts: we will first give some definitions of what a metaphor is; second, we will describe our case study and the results of the data analysis; third, we will discuss the results.
An Induced Demand Model for High Speed 1 in UK  [PDF]
Francesca Pagliara, John Preston
Journal of Transportation Technologies (JTTs) , 2013, DOI: 10.4236/jtts.2013.31005

Induced travel is an important component of travel demand and increasing attention has been paid to building analytical model to get more precise travel demand forecasting. In general, induced demand can be defined in terms of additional trips that would be made if travel conditions improved (less congested, lower vehicle costs or tolls). In this paper the induced demand resulting from higher design speeds and, therefore by less travel time, for the High Speed 1 in UK will be modelled on the basis of the relationship between existing High Speed Rail demand (dependent variable) to existing High Speed Rail travel times and costs. The covariates include socioeconomic variables related to population and employment in the zones connected by the High Speed Rail services. This model has been calibrated by mean of a before and after study carried on the corridor, when the new High Speed Rail services was introduced. Elasticities of induced travel (trips and VMT) have been computed with respect to fares, travel time and service frequency.

Wild food plants of popular use in Sicily
Francesca Lentini, Francesca Venza
Journal of Ethnobiology and Ethnomedicine , 2007, DOI: 10.1186/1746-4269-3-15
Abstract: Numerous scientific researches conducted in the last few years have revealed that a diet rich in fibre, complex carbohydrates, vitamins and mineral salts, is the diet considered most ideal in order to maintain good health and prevent various illnesses. Fruit and vegetables are the food that contains a large quantity of vitamins and it is mainly because of this that many researchers have focused their attention on the studies of nutritional plants.Many species have already been examined concerning this aspect but there are nevertheless many more which merit examination. Ethnobotany is a preliminary method of research, suitable for gathering information on the nutritional use of plants. It has been proven, time and time again, that the 'quack' medical knowledge handed down by the common people constitutes sources of information useful for scientific research and that many plants utilised exclusively in popular tradition, when exposed under scientific examination, have been found to be useful for different sectors in the industry [1]. Therefore, science and tradition have a strong connection between them; science, in fact, has often traditional origins.Considering the fact that ethnobotany mainly concentrates on the individuation of plants with an applicative purpose, the authors, that have shown an interest in the argument for a long time, have completed a research conducted on the plants used as food and/or for aromatic purposes in popular, Sicilian tradition and have referred to, in this contribution, the results obtained.One of the main objectives of this research is to individuate, amongst the plants of the Sicilian flora, those more or less known for their nutritional use and to provide suggestions on how to embark upon researches in the medical-nutritional field. In fact, many nutritional plants are also utilised for medical purposes and are often advised as a remedy in order to stabilise alternative functions of the human organism or simply to purify or cure so
Inflammation as a Link between Obesity and Metabolic Syndrome
Faloia Emanuela,Michetti Grazia,De Robertis Marco,Luconi Maria Paola,Furlani Giorgio,Boscaro Marco
Journal of Nutrition and Metabolism , 2012, DOI: 10.1155/2012/476380
Abstract: The metabolic syndrome is a complex of clinical features leading to an increased risk for cardiovascular disease and type 2 diabetes mellitus in both sexes. Visceral obesity and insulin resistance are considered the main features determining the negative cardiovascular profile in metabolic syndrome. The aim of this paper is to highlight the central role of obesity in the development of a chronic low-grade inflammatory state that leads to insulin resistance, endothelial and microvascular dysfunctions. It is thought that the starting signal of this inflammation is overfeeding and the pathway origins in all the metabolic cells; the subsequent increase in cytokine production recruits immune cells in the extracellular environment inducing an overall systemic inflammation. This paper focuses on the molecular and cellular inflammatory mechanisms studied until now.
Prolactinomas, Cushing's disease and acromegaly: debating the role of medical therapy for secretory pituitary adenomas
Beverly MK Biller, Annamaria Colao, Stephan Petersenn, Vivien S Bonert, Marco Boscaro
BMC Endocrine Disorders , 2010, DOI: 10.1186/1472-6823-10-10
Abstract: First-line treatment of prolactinomas is pharmacotherapy with dopamine agonists; recent reports of cardiac valve abnormalities associated with this class of medication in Parkinson's disease has prompted study in hyperprolactinemic populations. Patients with resistance to dopamine agonists may require other treatment.First-line treatment of Cushing's disease is pituitary surgery by a surgeon with experience in this condition. Current medical options for Cushing's disease block adrenal cortisol production, but do not treat the underlying disease. Pituitary-directed medical therapies are now being explored. In several small studies, the dopamine agonist cabergoline normalized urinary free cortisol in some patients. The multi-receptor targeted somatostatin analogue pasireotide (SOM230) shows promise as a pituitary-directed medical therapy in Cushing's disease; further studies will determine its efficacy and safety. Radiation therapy, with medical adrenal blockade while awaiting the effects of radiation, and bilateral adrenalectomy remain standard treatment options for patients not cured with pituitary surgery.In patients with acromegaly, surgery remains the first-line treatment option when the tumor is likely to be completely resected, or for debulking, especially when the tumor is compressing neurovisual structures. Primary therapy with somatostatin analogues has been used in some patients with large extrasellar tumors not amenable to surgical cure, patients at high surgical risk and patients who decline surgery. Pegvisomant is indicated in patients who have not responded to surgery and other medical therapy, although there are regional differences in when it is prescribed.In conclusion, the treatment of patients with pituitary adenomas requires a multidisciplinary approach. Dopamine agonists are an effective first-line medical therapy in most patients with a prolactinoma, and somatostatin analogues can be used as first-line therapy in selected patients with acromegal
Queratopatía cristalina: diagnóstico clínico y microbiológico de una infección corneal infrecuente causada por el grupo Streptococcus mitis
Galperín,Gustavo J; Boscaro,Gabriela; Tau,Julia; Berra,Martín;
Revista argentina de microbiolog?-a , 2011,
Abstract: crystalline keratopathy: an infrequent corneal infection produced by the streptococcus mitis group. the objective of this report is to describe a case of crystalline keratopathy caused by the streptococcus mitis group corresponding to a patient who attended hospital for discomfort in his right eye. the ophthalmological examination showed an interrupted stitch of 10-0 nylon suture without tension and with attached mucus secretions. the loose suture was removed under aseptic conditions. moxifloxacin 0.5 % eye drops were topically indicated. the treated eye successfully epithelialized and evolved favorably. however, after 15 days, a white tree-shaped infiltrate developed. a corneal sample was taken in the operating room, threading the intrastromal path of the removed stitch with a 7-0 vicryl suture. vancomycin 50 mg/ml drops were indicated. the infiltrate, which was stable for 45 days, later increased its size and tissue necrosis occurred with danger of corneal perforation. a bipedicle conjunctival flap was performed in the affected corneal area, which evolved favorably. after spontaneous conjunctival flap retraction, only corneal scarring and neovascularization outside the visual axis were observed.
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