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Search Results: 1 - 10 of 8505 matches for " Felipe;Castelo-Branco "
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Treatment of subclavian steal syndrome with percutaneous transluminal angioplasty and stenting: case report
Fregni Felipe,Castelo-Branco Luiz Eduardo Coutinho,Conforto Adriana Bastos,Yamamoto Fabio Iuji
Arquivos de Neuro-Psiquiatria , 2003,
Abstract: Subclavian steal syndrome refers to the association of neurological symptoms related to vertebrobasilar insufficiency and the phenomenon of subclavian steal. We report the case of a 63 year-old male patient that presented subclavian steal syndrome and severe proximal (80%) stenosis of the left subclavian artery. The patient was submitted to percutaneous transluminal angioplasty and stenting on the left SA. The procedure was well tolerated and immediately afterwards, there was complete remission of the symptoms and of the phenomenon of subclavian steal evaluated by angiography and transcranial doppler. We propose that percutaneous transluminal angioplasty with stenting placement is a good therapeutic option for subclavian steal syndrome.
Treatment of subclavian steal syndrome with percutaneous transluminal angioplasty and stenting: case report
Fregni, Felipe;Castelo-Branco, Luiz Eduardo Coutinho;Conforto, Adriana Bastos;Yamamoto, Fabio Iuji;Campos, Cynthia Resende;Puglia Jr., Paulo;Caldas, José Guilherme Mendes Pereira;Scaff, Milberto;
Arquivos de Neuro-Psiquiatria , 2003, DOI: 10.1590/S0004-282X2003000100018
Abstract: subclavian steal syndrome refers to the association of neurological symptoms related to vertebrobasilar insufficiency and the phenomenon of subclavian steal. we report the case of a 63 year-old male patient that presented subclavian steal syndrome and severe proximal (80%) stenosis of the left subclavian artery. the patient was submitted to percutaneous transluminal angioplasty and stenting on the left sa. the procedure was well tolerated and immediately afterwards, there was complete remission of the symptoms and of the phenomenon of subclavian steal evaluated by angiography and transcranial doppler. we propose that percutaneous transluminal angioplasty with stenting placement is a good therapeutic option for subclavian steal syndrome.
Bebês: o irresistível poder da graciosidade. Um estudo sobre o significado evolutivo dos tra？os infantis
Leit？o, Monique;Castelo-Branco, Rochele;
Estudos de Psicologia (Natal) , 2010, DOI: 10.1590/S1413-294X2010000100010
Abstract: babies generally elicit tenderness and caretaking behaviors on people. the aim of this study is to discuss the attraction towards babyish features, taking tinbergen's four questions as a theoretical benchmark. concerning the mechanisms implicated in this neonatal attraction, we evaluated the importance of children′s morphology on eliciting parental responses. considering the adaptive function of this characteristic, we discuss the evolutionary process that shaped the preferences towards infantile traits as well as the phylogeny of the preference towards infant′s morphological traits. it was also presented data about the development of this behavioral trait across life span. the information provided here suggests a reason why we find babies such irresistible creatures.
Capacidade antioxidante total de óleos vegetais comestíveis: determinantes químicos e sua rela？？o com a qualidade dos óleos
Castelo-Branco, Vanessa Naciuk;Torres, Alexandre Guedes;
Revista de Nutri？？o , 2011, DOI: 10.1590/S1415-52732011000100017
Abstract: the total antioxidant capacity of edible vegetable oils is determined by their physical-chemical composition and might be associated with their quality attributes, especially with bioactivity and possibly with oxidative stability. the current review presents the fundamentals of total antioxidant capacity assays and critically evaluates the assays applicable to the analysis of oils. the role of the chemical components of edible oils as determinants of total antioxidant capacity is discussed, as well as the potential associations between antioxidant capacity and bioactivity or oxidative stability of the selected oils. finally, we discuss evidences that, if systematically addressed in future experimental work, the application of total antioxidant capacity assays to vegetable oils might contribute to link the knowledge about their chemical composition with their bioactivity, and possibly with the stability of specific vegetable oils. thus, antioxidant capacity assays can potentially be used for the quality control of edible oils.
Understanding Tremor in Rapid Upper Limb Movements Using 3D Accelerometers Data  [PDF]
Paula Pascoal-Faria, Miguel Patrício, Adriana Leal, Francisco Caramelo, António Freire, Cristina Januário, Miguel Castelo-Branco
Neuroscience & Medicine (NM) , 2014, DOI: 10.4236/nm.2014.55024
Abstract: Tremor is a manifestation of a variety of human neurodegenerative diseases, notably Parkinson’s disease (PD) and Essential Tremor (ET), both affecting millions worldwide. PD is primarily caused by a progressive loss of dopamine neurons in the nigrostriatal system that leads to widespread motor symptoms such as bradykinesia, rigidity, tremor and postural instability. ET typically involves a tremor of the arms, hands or fingers. No definitive test or biomarker is yet available for PD or ET, so the rate of misdiagnosis is relatively high. As tremor is a very common feature at the onset of both diseases, it is crucial to be able to characterize it. This is made possible using acce?lerometers to quantify the tremor amplitude and frequency. In this work we aim to find tasks involving upper limb movements that are suitable to modulate both types of tremor. Four tasks were tested, differing on whether the arms moved together or alternatingly and whether loads were added. Significant differences in tremor measures were found when patients were asked to perform simultaneous rapid arms movements with loads placed on their wrists. These results may allow the design of an efficient fMRI protocol for identifying the cortical circuits responsible for the modulation of tremor.
A Direct Comparison of Local-Global Integration in Autism and other Developmental Disorders: Implications for the Central Coherence Hypothesis
Inês Bernardino, Susana Mouga, Joana Almeida, Marieke van Asselen, Guiomar Oliveira, Miguel Castelo-Branco
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0039351
Abstract: The weak central coherence hypothesis represents one of the current explanatory models in Autism Spectrum Disorders (ASD). Several experimental paradigms based on hierarchical figures have been used to test this controversial account. We addressed this hypothesis by testing central coherence in ASD (n = 19 with intellectual disability and n = 20 without intellectual disability), Williams syndrome (WS, n = 18), matched controls with intellectual disability (n = 20) and chronological age-matched controls (n = 20). We predicted that central coherence should be most impaired in ASD for the weak central coherence account to hold true. An alternative account includes dorsal stream dysfunction which dominates in WS. Central coherence was first measured by requiring subjects to perform local/global preference judgments using hierarchical figures under 6 different experimental settings (memory and perception tasks with 3 distinct geometries with and without local/global manipulations). We replicated these experiments under 4 additional conditions (memory/perception*local/global) in which subjects reported the correct local or global configurations. Finally, we used a visuoconstructive task to measure local/global perceptual interference. WS participants were the most impaired in central coherence whereas ASD participants showed a pattern of coherence loss found in other studies only in four task conditions favoring local analysis but it tended to disappear when matching for intellectual disability. We conclude that abnormal central coherence does not provide a comprehensive explanation of ASD deficits and is more prominent in populations, namely WS, characterized by strongly impaired dorsal stream functioning and other phenotypic traits that contrast with the autistic phenotype. Taken together these findings suggest that other mechanisms such as dorsal stream deficits (largest in WS) may underlie impaired central coherence.
Stimulus Dependency of Object-Evoked Responses in Human Visual Cortex: An Inverse Problem for Category Specificity
Britta Graewe, Peter De Weerd, Reza Farivar, Miguel Castelo-Branco
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0030727
Abstract: Many studies have linked the processing of different object categories to specific event-related potentials (ERPs) such as the face-specific N170. Despite reports showing that object-related ERPs are influenced by visual stimulus features, there is consensus that these components primarily reflect categorical aspects of the stimuli. Here, we re-investigated this idea by systematically measuring the effects of visual feature manipulations on ERP responses elicited by both structure-from-motion (SFM)-defined and luminance-defined object stimuli. SFM objects elicited a novel component at 200–250 ms (N250) over parietal and posterior temporal sites. We found, however, that the N250 amplitude was unaffected by restructuring SFM stimuli into meaningless objects based on identical visual cues. This suggests that this N250 peak was not uniquely linked to categorical aspects of the objects, but is strongly determined by visual stimulus features. We provide strong support for this hypothesis by parametrically manipulating the depth range of both SFM- and luminance-defined object stimuli and showing that the N250 evoked by SFM stimuli as well as the well-known N170 to static faces were sensitive to this manipulation. Importantly, this effect could not be attributed to compromised object categorization in low depth stimuli, confirming a strong impact of visual stimulus features on object-related ERP signals. As ERP components linked with visual categorical object perception are likely determined by multiple stimulus features, this creates an interesting inverse problem when deriving specific perceptual processes from variations in ERP components.
Compliance and enforcement of a partial smoking ban in Lisbon taxis: an exploratory cross-sectional study
Sofia B Ravara, Miguel Castelo-Branco, Pedro Aguiar, Jose M Calheiros
BMC Public Health , 2013, DOI: 10.1186/1471-2458-13-134
Abstract: Exploratory cross-sectional study; purposive sampling in selected Lisbon streets. Structured interviews were conducted by trained researchers while using taxi services (January 2009-December 2010). Participants: 250 taxi drivers (98.8% participation rate). Chi-square, McNemar, Man Whitney tests and multiple logistic regression were performed.Of the participants, 249 were male; median age was 53.0？years; 43.6% were current smokers. Most participants (82.8%) approved comprehensive bans; 84.8% reported that clients still asked to smoke in their taxis; 16.8% allowed clients to smoke. Prior to the ban this value was 76.9% (p？<？0.001). The major reason for not allowing smoking was the legal ban and associated fines (71.2%). Of the smokers, 66.1% admitted smoking in their taxi. Stale smoke smells were detected in 37.6% of the cars. None of the taxi drivers did ever receive a fine for non-compliance. Heavy smoking, night-shift and allowing smoking prior the ban predicted non-compliance.Despite the strong ban support observed, high smoking prevalence and poor enforcement contribute to low compliance. The findings also suggest low compliance among night-shift and vehicle workers. This study clearly demonstrates that a partial and poorly-enforced ban is vulnerable to breaches, and highlights the need for clear and strong policies.Worldwide, tobacco remains a leading preventable cause of death, killing nearly 6 million people each year, including more than 600,000 who had been exposed to second-hand smoke (SHS) [1]. Enacting 100% smoke-free policies (SFPs) is the only effective way to eliminate SHS and its consequences [2]. Examples from countries where comprehensive SFPs have been adopted, with few exemptions and no allowance for smoking areas in hospitality venues, teach us that good compliance and self-regulation can be achieved [1-6]. Good smoke-free policies become self-enforced over time, relying on self-regulation and changes in social norms. These changes occur when com
Blood pressure control and antihypertensive pharmacotherapy patterns in a hypertensive population of Eastern Central Region of Portugal
Manuel P Morgado, Sandra A Rolo, Luísa Pereira, Miguel Castelo-Branco
BMC Health Services Research , 2010, DOI: 10.1186/1472-6963-10-349
Abstract: The objectives of this study were to evaluate blood pressure control and antihypertensive pharmacotherapy patterns in a population of Eastern Central Region of Portugal, attending a hospital outpatient clinic (ambulatory setting) for routine follow-up.Medical data of all patients that attended at least two medical appointments of hypertension/dyslipidemia in a university hospital over a one and a half year period (from January 2008 to June 2009) were retrospectively analysed. Demographic variables, clinical data and blood pressure values of hypertensive patients included in the study, as well as prescribing metrics were examined on a descriptive basis and expressed as the mean ± SD, frequency and percentages. Student's test and Mann-Whitney rank sum test were used to compare continuous variables and χ2 test and Fisher exact probability test were used to test for differences between categorical variables.In all, 37% of hypertensive patients (n = 76) had their blood pressure controlled according to international guidelines. About 45.5% of patients with a target blood pressure <140/90 mmHg (n = 156) were controlled, whereas in patients with diabetes or chronic kidney disease (n = 49) the corresponding figure was only 10.2% (P < 0.001). Among patients initiating hypertension/dyslipidemia consultation within the study period 32.1% had stage 2 hypertension in the first appointment, but this figure decreased to 3.6% in the last consultation (P = 0.012). Thiazide-type diuretics were the most prescribed antihypertensive drugs (67%) followed by angiotensin receptor blockers (60%) and beta-blockers (43%). About 95.9% patients with comorbid diabetes were treated with an angiotensin-converting enzyme inhibitor or an angiotensin receptor blocker.Clinically important blood pressure decreases can be achieved soon after hypertension medical appointment initiation. However, many hypertensive patients prescribed with antihypertensive therapy fail to achieve blood pressure control in c
Caracteriza？？o inorganica de cinza volante de uma esta？？o de incinera？？o de resíduos sólidos urbanos com vista à sua eventual reciclagem
Varela,A.; Ribeiro,A. B.; Monteiro,O.; Lima,A.T.; Castelo-Branco,M. A.;
Revista de Ciências Agrárias , 2009,
Abstract: fly ashes from municipal solid waste incinerators (mswi) are considered hazardous waste. in portugal, they are expected to increase over time which poses a growing concern about the waste management issue they represent. the use of landfills for fly ash disposal is currently the main option in many countries. since a variety of heavy metals concentrate in fly ash, mainly deposited on the surface of particles, making them more apt to leach, the ash need to be stabilized prior to disposal, to reduce their environmental impact, which is done by the addition of cement. the electrodialytic process (ed) promisingly removes heavy metals from fly ash, enabling their further valorisation (e.g. as a soil amendment or for incorporation in construction products) and the recovery of heavy metals for further reuse. the ed uses a low-level dc current as the "cleaning agent", combining the electrokinetic movement, with the principle of electrodialysis. the project pocti/agg/45073/2002, currently being carried out, aims at studying the application of the ed, in order to maximize heavy metals removal from this contaminated media. in this work the inorganic fraction of fly ash are characterized.
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