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Search Results: 1 - 10 of 402655 matches for " Fausto M Angeles "
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Dietary antioxidants protect gut epithelial cells from oxidant-induced apoptosis
Mark JS Miller, Fausto M Angeles, Brian K Reuter, Paul Bobrowski, Manuel Sandoval
BMC Complementary and Alternative Medicine , 2001, DOI: 10.1186/1472-6882-1-11
Abstract: Cultured human gastric epithelial cells (AGS) or murine small intestinal epithelial cells (IEC-18) were exposed to oxidants – DPPH (3 μM), H2O2 (50 μM), peroxynitrite (300 μM) – followed by incubation for 24 hours, with antioxidants (10 μg/ml) administered as a 1 hour pretreatment. Cell number (MTT assay) and death via apoptosis or necrosis (ELISA, LDH release) was determined. The direct interactions between antioxidants and DPPH (100 μM) or H2O2 (50 μM) were evaluated by spectroscopy.The decoctions did not interact with H2O2, but quenched DPPH although less effectively than vitamin C. In contrast, vitamin C was significantly less effective in protecting human gastric epithelial cells (AGS) from apoptosis induced by DPPH, peroxynitrite and H2O2 (P < 0.001). Green tea and cat's claw were equally protective against peroxynitrite and H2O2, but green tea was more effective than cat's claw in reducing DPPH-induced apoptosis (P < 0.01). Necrotic cell death was marginally evident at these low concentrations of peroxynitrite and H2O2, and was attenuated both by cat's claw and green tea (P < 0.01). In IEC-18 cells, all antioxidants were equally effective as anti-apoptotic agents.These results indicate that dietary antioxidants can limit epithelial cell death in response to oxidant stress. In the case of green tea and cat's claw, the cytoprotective response exceed their inherent ability to interact with the injurious oxidant, suggestive of actions on intracellular pathways regulating cell death.Epithelial apoptosis in the gastro-intestinal tract is normally restricted to superficial cells but in pathological states of inflammation or infection, apoptotic cell death can be far more expansive. Under these conditions apoptosis may result from the production of cytokines [1], cell activation [2-4], infective agents [5] and adverse responses to pharmaceuticals [6,7]. Depending on the agonist or eliciting milieu, apoptotic cell death is accompanied by the activation of various cell
La Arqueología Histórica en Epoca Romana en Navarra.
M. Angeles Mezquiriz Irujo
Munibe Antropologia-Arkeologia , 1990,
Abstract: Se ofrece la historiografía de las investigaciones sobre época romana realizadas en Navarra.
Rich-club vs rich-multipolarization phenomena in weighted networks
M. Angeles Serrano
Physics , 2008, DOI: 10.1103/PhysRevE.78.026101
Abstract: Large scale hierarchies characterize complex networks in different domains. Elements at their top, usually the most central or influential, may show multipolarization or tend to club forming tightly interconnected communities. The rich-club phenomenon quantified this tendency based on unweighted network representations. Here, we define this metric for weighted networks and discuss the appropriate normalization which preserves nodes' strengths and discounts structural strength-strength correlations if present. We find that in some real networks the results given by the weighted rich-club coefficient can be in sharp contrast to the ones in the unweighted approach. We also discuss that the scanning of the weighted subgraphs formed by the high-strength hubs is able to unveil features contrary to the average: the formation of local alliances in rich-multipolarized environments, or a lack of cohesion even in the presence of rich-club ordering. Beyond structure, this analysis matters for understanding correctly functionalities and dynamical processes relying on hub interconnectedness.
Solving the Nose-Hoover thermostat for Nuclear Pasta
M. Angeles Perez Garcia
Physics , 2006, DOI: 10.1063/1.2218236
Abstract: In this work we present a calculation of the hamiltonian variables solving the molecular dynamics equations of motion for a system of nuclear matter relevant to the description of nuclear pasta. The temperature is kept fixed by using the Nos\'{e}-Hoover Thermostat and the interaction is modelled via a semiclassical potential depending on both positions and momenta.
Phase transition in the globalization of trade
M. Angeles Serrano
Quantitative Finance , 2006, DOI: 10.1088/1742-5468/2007/01/L01002
Abstract: Globalization processes interweave economic structures at a worldwide scale, trade playing a central role as one of the elemental channels of interaction among countries. Despite the significance of such phenomena, measuring economic globalization still remains an open problem. More quantitative treatments could improve the understanding of globalization at the same time that help a formal basis for comparative economic history. In this letter, we investigate the time evolution of the statistical properties of bilateral trade imbalances between countries in the trade system. We measure their cumulative probability distribution at different moments in time to discover a sudden transition circa 1960 from a regime where the distribution was always represented by a steady characteristic function to a new state where the distribution dilates as time goes on. This suggests that the rule that was governing the statistical behavior of bilateral trade imbalances until the 60's abruptly changed to a new form persistent in the last decades. In the new regime, the figures for the different years collapse into a universal master curve when rescaled by the corresponding global gross domestic product value. This coupling points to an increased interdependence of world economies and its onset corresponds in time with the starting of the last globalization wave.
Editorial
Fausto Borém
Per Musi , 2012,
Abstract:
Editorial
Fausto Borém
Per Musi , 2009, DOI: 10.1590/s1517-75992009000100001
Abstract:
Editorial
Fausto Borém
Per Musi , 2012, DOI: 10.1590/s1517-75992012000100001
Abstract:
Editorial
Fausto Borém
Per Musi , 2009, DOI: 10.1590/s1517-75992009000200001
Abstract:
Editorial
Fausto Borém
Per Musi , 2013,
Abstract:
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