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Search Results: 1 - 10 of 468995 matches for " Fatma A. Mohamed "
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Nonlinear Uncertain HIV-1 Model Controller by Using Control Lyapunov Function  [PDF]
Fatma A. Alazabi, Mohamed A. Zohdy
International Journal of Modern Nonlinear Theory and Application (IJMNTA) , 2012, DOI: 10.4236/ijmnta.2012.12004
Abstract: In this paper, we introduce a new Control Lyapunov Function (CLF) approach for controlling the behavior of nonlinear uncertain HIV-1 models. The uncertainty is in decay parameters and also external control setting. CLF is then applied to different strategies. One such strategy considers input into infected cells population stage and the other considers input into a virus population stage. Furthermore, by adding noise to the HIV-1 model a realistic comparison between control strategies is presented to evaluate the system’s dynamics. It has been demonstrated that nonlinear control has effectiveness and robustness, in reducing virus loading to an undetectable level.
Synthesis of Novel Acid Dyes with Coumarin Moiety and Their Utilization for Dyeing Wool and Silk Fabrics  [PDF]
Mahmoud S. Bashandy, Fatma A. Mohamed, Mohamed M. El-Molla, Mahmoud B. Sheier, Ahmed H. Bedair
Open Journal of Medicinal Chemistry (OJMC) , 2016, DOI: 10.4236/ojmc.2016.61002
Abstract: This article describes the synthesis of some novel coumarin compounds to use as acid dyes by using compounds 1 - 4 as starting materials, which were prepared by interaction of 2-hydroxybenzaldehyde with ethyl 3-oxobutanoate, diethylmalonate, 4-nitrobenzenediazonium chloride and 4-sulfobenzenediazonium chloride, respectively. Compound 1 reacted with bromine and 2-cyanoacetohydrazide to give phenacyl bromide derivative 5 and 2-cyanoacetohydrazone derivative 6, respectively. Coupling of compound 6 with equimolar amount of 2-sulfo-4-((4-sulfophenyl) diazenyl)benzenediazonium chloride gave coumarin acid dye 8. Phenacyl bromide derivative 5 re-acted with potassium cyanide in refluxing ethanol to produce compound 7, which on coupling with equimolar amount of 8-hydroxy-6-sulfonaphthalene-2-diazonium chloride and 8-hydroxy-3,6-disulfonaphthalene-1-diazonium chloride gave coumarin acid dyes 9 and 10, respectively. Interaction of compound 2 with 2-amino-5-((4-sulfophenyl)diazenyl)benzenesulfonic acid, benzene-1,4-diamine and 3,3’-dimethoxy-[1,1’-biphenyl]-4,4’-diamine in refluxing ethanol afforded compounds 11, 12 and 14, respectively. Diazonium sulphate of compounds 12 and 14 coupling with 4-amino-5-hydroxynaphthalene-2,7-disulfonic acid gave compounds 13 and 15, respectively. Cyclocondensation of compound 3 with ethyl 3-oxobutanoate, diethyl malonate and malononitrile afforded derivatives of 3-acetyl-2H-chromen-2-one 16, ethyl 2-oxo-2H-chromene-3-carboxylate 17 and 2-imino-2H-chromene-3-carbonitrile 18, respectively. Reaction of sodium benzenesulfonate derivative 4 with ethyl 3-oxobutanoate and hydrazine hydrate gave compounds 19 and 20, respectively. The structures of the newly synthesized compounds were confirmed by elemental analysis, UV/ VIS, IR, 1H NMR and Ms spectral data. The suitability of the prepared dyestuffs for dyeing of wool and silk fabrics has been investigated. The dyed fabric shows good light fastness, very good rubbing, perspiration, washing and excellent sublimation fastness. These dyes have been color shade from blue to violet with very good depth and levelness on fabrics. The dye bath exhaustion and fixation on fabric has been found to be very good.
Growth, chemical composition and soil properties of Tipuana speciosa (Benth.) Kuntze seedlings irrigated with sewage effluent
Hayssam M. Ali,Mohamed H. Khamis,Fatma A. Hassan
Applied Water Science , 2012, DOI: 10.1007/s13201-012-0027-4
Abstract: This study was carried out at a greenhouse of Sabahia Horticulture Research Station, Alexandria, Egypt, to study the effect of sewage effluent on the growth and chemical composition of Tipuana speciosa (Benth.) Kuntze seedlings as well as on soil properties for three stages. The irrigation treatments were primary-treated wastewater and secondary-treated wastewater, in addition to tap water as control. Therefore, the treated wastewater was taken from oxidation ponds of New Borg El-Arab City. Results of these study revealed that the primary effluent treatment explored the highest significant values for vegetative growth and biomass, compared to the other treatments. In addition, the higher significant concentration and uptake of chemical composition in different plant parts were obtained from the primary effluent treatment during the three stages of irrigation. It was found that the concentration of heavy metals in either plant or soil was below as compared to the world-recommended levels. These findings suggested that the use of sewage effluent in irrigating T. speciosa seedlings grown in calcareous soil was beneficial for the improvement of soil properties and production of timber trees, and also important for the safe manner of disposal of wastewater.
Inhibition Mechanism of Pitting Corrosion of Nickel in Aqueous Medium by Some Macrocyclic Compounds  [PDF]
Fatma Mohamed Mahgoub, Ahmed Mohamed Hefnawy
Open Journal of Physical Chemistry (OJPC) , 2012, DOI: 10.4236/ojpc.2012.24030
Abstract: Anodic polarization of nickel was studied by potentiostatic technique in neutral media in presence of two macrocyclic ligands. Pit initiation was detected by measuring pitting potential, Ep and the charge transfer, Q during the anodic polarization. Initiation of pitting and Q were found to be dependent on the structure and concentrations of inhibitors. Under steady state conditions, the inhibition efficiency was in the order 1, 4, 8, 11 tetraazacyclotetradecane (cyclam) > N, N’-bis (2-aminoethyl) 1, 3-propandiamine (2,3,2-tet) due to macrocyclic effect. These findings were confirmed by fitting the data to different adsorption isotherms. Adsorption on nickel surface was obeyed kinetic-thermodynamic model for the two inhibitors. Influence of [Cl] on corrosion behavior of nickel in sulphate solution containing inhibitors was investigated. A mechanism involving three competitive equilibria of dissolution of nickel in presence and absence of the inhibitors was proposed. Empirical and theoretical kinetic equations were compared and discussed. There is a good agreement between the calculated and observed rate constants.
DFT Calculations for Corrosion Inhibition of Ferrous Alloys by Pyrazolopyrimidine Derivatives  [PDF]
Nuha Ahmed Wazzan, Fatma Mohamed Mahgoub
Open Journal of Physical Chemistry (OJPC) , 2014, DOI: 10.4236/ojpc.2014.41002

The inhibition performance of 5-tolyl-2-phenylpyrazolo[1,5-c] pyrimidine-7(6H)thione (Tolyl), 5-tolyl-2-pheenylpyrazolo [1,5-c]pyrimidine-7(6H)one (Inon) was investigated as corrosion inhibitors using density functional theory (DFT) at the B3LYP/6-31 + G(d,p) level of theory. The calculated quantum chemical parameters correlated to the inhibition efficiency are: the highest occupied molecular orbital energy(EHOMO), the lowest unoccupied molecular orbital energy (ELUMO), the energy gap (ΔEL-H), dipole moment (μ), ionization energy (Ι), electron affinity (Α), absolute electronegativity (χ), absolute hardness (η), absolute softness (σ), the fraction of electron transferred (ΔN), and the total energy (Etot) which were calculated. The local reactivity has been analyzed through the Fukui function and local softness indices in order to compare the possible sites for nucleophilic and electrophilic attacks. The success of DFT calculations in predicting the inhibition efficiency was assessed.

Cyclophosphamide and Etoposide as a Salvage Treatment in Metastatic Osteosarcoma Patients  [PDF]
Fatma MF Akl, Mohamed Farouk Akl
Journal of Cancer Therapy (JCT) , 2018, DOI: 10.4236/jct.2018.97044
Abstract: Background and Objective: Osteosarcoma is a rare bone cancer with approximately 30% - 35% of patients who will relapse either systemically or locally, with the lung being the commonest site of relapse. The objective of this trial was to evaluate the efficacy of cyclophosphamide and etoposide, in treatment of metastatic osteosarcoma patients progressed after one or more chemotherapy lines, with the progression free survival and treatment response as the primary endpoints, while the secondary endpoints were overall survival and treatment toxicity. Patients and Methods: Twenty seven metastatic osteosarcoma patients were enrolled into this trial and received cyclophosphamide and etoposide chemotherapy. Cyclophosphamide was given at a dose of 500 mg/m2 per day, I.V for 5 days and etoposide (100 mg/m2 per day I.V for 5 days). Response was assessed after 3 cycles according to Response Evaluation Criteria in Solid Tumors (RECIST) version 1.1. Chemotherapy Toxicity was graded according to the Common Terminology Criteria for Adverse Events (CTCAE). Results: The median overall survival time and progression-free survival were 12 months and 8 months, respectively. Four patients (14.8%) achieved partial response; 14 patients (51.9%) had stationary disease (SD); and 9 (33.3%) expressed tumor progression. Hematologic toxicity was the main toxicity. None of the patients had G4 or life threatening toxicities. Conclusion: The combination of cyclophosphamide and etoposide represents an efficient and tolerable treatment option for patients with metastatic osteosarcoma.
A New Approach for Converting Renewable Energy to Stable Energy  [PDF]
Mohamed Talaat, Reda Edris, Naglaa Ibrahim, Fatma Omar, Mohamed Ibrahim
Engineering (ENG) , 2013, DOI: 10.4236/eng.2013.510A005
Abstract: A renewable energy plant which relies on wind speed or solar insolation is unreliable because of the stochastic nature of weather patterns. It is theorized that by using multiple renewable energy plants in separate areas of a region, the different weather conditions might approach a probabilistically independent relationship. The goal of this paper is to utilize the power system technology to help disseminate wind and solar power systems to get a stable energy. A new approach to get appropriate stable energy is achieved by using the interrupted energy that obtained from wind farm and solar insolation. This is achieved by lifting water to a higher level with appropriate pumps and storing it in the form of potential energy. Then a stable energy is obtained by reliving water to the lower level. In this paper, the efficiency obtained from the renewable energy is compared with that obtained from traditional ones. An experimental model to simulate the process of converting the renewable energy to a stable energy is presented. The obtained results from experimental model explained that the renewable energy can be converted to a stable one with high efficiency.
Quality Evaluation of Some Fresh and Imported Frozen Seafood
Fatma Hassan Mohamed Ali
Advance Journal of Food Science and Technology , 2011,
Abstract: This work was done to evaluate the quality parameters of fresh and imported frozen seafood (fillets and shrimp). A total of 120 seafood samples, fillets and shrimp (fresh and imported frozen) 30 each, collected from fish markets at Giza Governorate were sensory, bacteriological, chemical investigated. Panelists rejected 5.0 (16.6%) and 0.0 (0.0%) of fresh fillets and shrimp samples, while the number raised up to 12.0 (40.0%) and 15.0 (50.0%) of frozen fillets and shrimp samples respectively. Fresh seafood had a significant lower (p<0.05) pH values in compared to frozen products. There were observed significant difference (p<0.05) in the TBA and TVB-N values between the fresh and frozen seafood samples. All fresh and frozen seafood samples were judge as safe food from microbiological point of view. The total proteolytic, lipolytic, psychrotrophic and pseudomonas/aeromonas counts for all examined seafood samples were lie within the standard permissible limits. L. monocytogenes could not be detected from fresh or frozen fillets. Few freqyency of L. monocytogenes found in fresh and imported frozen shrimp. As well as V. parahaemolyticus and Y. enterocolitica were recovered from examined fresh and frozen seafood samples. The public health significance of the isolated organisms was also discussed. The quality of fresh fillets and shrimp were better than that of imported frozen one.
Polyphenolic Profile and Bioactivity Study of Oenothera speciosa Nutt. Aerial Parts
Mohamed S. Marzouk,Fatma A. Moharram,Rabab A. El Dib,Siham M. El-Shenawy,Ahmed F. Tawfike
Molecules , 2009, DOI: 10.3390/molecules14041456
Abstract: Two new flavonol glycosides, myricetin 4'-O-α-L-rhamnopyranoside (1) and quercetin 3'-O-α-L-rhamnopyranoside (2), together with a novel biflavonol compound, speciin (3), as well as eleven phenolic metabolites, namely myricitrin (4), europetin 3-O-α-L-1C4-rhamnopyranoside (5), quercitrin (6), hyperin (7), rhamnetin 3-O-β-galacto-pyranoside (8), caffeic acid (9), caffeic acid methyl ester (10), chlorogenic acid (11), chlorogenic acid methyl ester (12), gallic acid (13) and gallic acid methyl ester (14), were identified from the 80 % methanol extract of the aerial parts (leaves and stems) of Oenothera speciosa Nutt. (Onagraceae). In addition myricetin (15), quercetin (16) and ellagic acid (17) were identified from the chloroform extract. The structures were established depending on their chemical and physical analyses (UV, HR-ESIMS, 1D and 2D NMR). It was found that 80 % aqueous methanol extract of O. speciosa is non-toxic to mice up to 5 g kg-1b.wt. The investigated extract exhibited significant antihyperglycaemic and anti-inflammatory activities in a dose dependant manner. Also, the 80 % methanol extract, myricitrin(4) and hyperin(7) showed potent antioxidant activity in vitro using 1,1-diphenyl 2-picryl hydrazyl (DPPH) radical assay.
Prevalence of transfusion transmitted virus (TTV) genotypes among HCC patients in Qaluobia governorate
Mohamed M Hafez, Sabry M Shaarawy, Amr A Hassan, Rabab F Salim, Fatma M Abd El Salam, Amal E Ali
Virology Journal , 2007, DOI: 10.1186/1743-422x-4-135
Abstract: TTV are determined in the serum of 60 samples obtained from HCC and liver cirrhosis (LC) patients and 30 healthy individuals. TTV DNA is amplified by nested-PCR with TTV-specific mixed primers derived from the conserved open reading frame 1 (ORF1) region followed by digestion with restriction enzyme. Using the enzymes HaeIII, DraI, EcoRI and PstI, we are able to distinguish between the four TTV genotypes.The positive rate of TTV detection was 46.7%, 40% and 36.7% among HCC, LC patients and healthy individuals respectively. The more prevalence genotype was detected in the positive serum samples was genotype 1 (35.7%) in HCC patients, (50%) in LC and (63.3%) in healthy individuals, Genotype 5 (21.4%), (25.5%) and (18.2%) in HCC, LC and healthy individuals respectively.This study indicates that TTV is commonly present in adult patients with HCC and LC as well as healthy individuals. The most prevalence TTV genotype is genotype 1. It seems that the infection neither contribute to the severity of liver disease no to the causation of HCC.Hepatocellular carcinoma (HCC) is the fifth most common cancer but the third leading cause of cancer death in the world. The major etiology of HCC/liver cancer in people is hepatitis B virus (HBV), followed by hepatitis C virus infection (HCV). A small single-stranded DNA virus, named TT virus (TTV), was discovered in Japan from patients with non-A-G transfusion-acquired hepatitis [1]. Knowledge about novel hepatotropic virus TTV is growing fast, but some fundamental aspects remain to be elucidated. Its prevalence and clinical significance are being assessed worldwide, however its relationship with aggravation and progression to severe liver disease and HCC remain controversial. TTV DNA has been detected in many healthy and the diversity of the strains of the virus has been reported [2]. TTV DNA was detected in 12% of healthy blood donors, although the serological prevalence of TTV infection in healthy blood donors was lower than that in
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