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Search Results: 1 - 10 of 1378 matches for " Fatemeh;Javadian "
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Biochemical association between essential trace elements and susceptibility to Leishmania major in BALB/c and C57BL/6 mice
Amini, Marzyeh;Nahrevanian, Hossein;Khatami, Shohreh;Farahmand, Mahin;Mirkhani, Fatemeh;Javadian, Seifoddin;
Brazilian Journal of Infectious Diseases , 2009, DOI: 10.1590/S1413-86702009000200002
Abstract: several enzymes that contribute to immune system responses require zinc and copper as trace elements for their activity. we examined zinc and copper levels in two susceptible balb/c mouse lines and resistant c57bl/6 mice infected with leishmania major mrho/ir/75/er, a prevalent strain that causes cutaneous leishmaniasis in iran. serum zn and cu were determined by flame atomic absorption spectrophotometry. higher cu levels were found in infected c57bl/6 mice and higher zn levels were found in infected balb/c mice. also, cu/zn ratios were increased in both the balb/c and the c57bl/6 mice. we conclude that concentrations of essential trace elements vary during cutaneous leishmaniasis infection and that this variation is associated with susceptibility/resistance to leishmania major in balb/c and c57bl/6 mice. we detected zn deficiency in the plasma of infected balb/c mice; possibly, therapeutic administration of zn would be useful for treating this form of leishmaniasis. increases in cu level might increase resistance to leishmaniasis. based on our findings, the cu/zn ratio could be a useful marker for the pathophysiology of leishmaniasis.
Giant papillary conjunctivitis: A study of 700 cases
Javadian A
Tehran University Medical Journal , 1995,
Abstract: In view of the rapid expansion of contact lens amongst the users, new dimensions have been added to the domain of ophthalmology: Giant papillay conjunctivitis, a disease caused by different kinds of contact lens, appears weeks or months after they are used, although some patients are struck years later. The predominant symptoms are increased awareness of lenses, ocular itching, blurred vision and excessive lens movement. The predominant signs are the formation of papillae, the presence of excessive mucus, and contact lens coatings. The syndrome occurs mostly with the soft lens and is more intense. Other independent studies show that the rate of prevalence of the disease with soft lenses and hard lenses is 10% and 5% respectively. The study comprised 550 soft lenses and 150 hard lenses. The diagnosis of the disease was based on the symptoms and signs of the disease. Eleven percent of the patients using soft lens and 4% of the patients using hard lens had the disease at some stage. Almost all of the patients were using dirty and low grade lenses. The therapy protocol of the disease consisted of changing the polymer type of the lens and administering cromolyn 4% drop. In cases that the therapy was unsuccessful, a temporary suspension of the lens and administration of cromolyn 4% was recommended before using the new lens.
Botulinum toxin for treatment of blepharospasm and hemifacial spasm
Soltanzadeh A,Javadian MDA
Tehran University Medical Journal , 1997,
Abstract: Botulinum toxin produced by Clostridium butolinum in one of the most fatal toxins known. Botulism is the name given to condition produced by this toxin. In recent years the diluted form of this toxin has been produced in injection form and used for treatment of hemifacial spasm and blepharospasm. This toxin blocks neuromuscular junction and inhibits acetylcholine release. In this article we reported 36 patients suffering from hemifacial & blepharospasm treated by injections of botulinum A toxin. 85 to 90 percent of patients responded well. The common complications of this drug were ptosis, hemifacial paresis, burning of the mouth and discoloration of the injection site. Generally speaking the patients preferred this toxin to taking oral medications which were less effective.
Abnormal MRI in acute optic neuritis and follow-up of patients with regard to multiple sclerosis
Soltanzadeh A,Javadian A
Tehran University Medical Journal , 1997,
Abstract: Twenty cases of isolated optic neuritis (15 female, 5 male) were studied and followed for several months to years after the initial attack. The mean age of patients was 23 years (range: 15-29 years). The most frequent clinical manifestations were decreased visual acuity and blurred vision. A complete neurological examination was performed. In 15 cases (75%) the initial brain MRI was abnormal. In fourteen cases, other signs of multiple sclerosis presented in one month to eight years following the initial attack of optic neuritis; eleven of the latter cases had an abnormal initial MRI. Acute optic neuritis can be considered a presenting feature of multiple sclerosis, particulary in the presence of an abnormal brain MRI.
Some Ecological Characteristics of Phlebotomine sandflies in a Focus of Cutaneous Leishmaniasis, Chabahar, Iran
Hamid Kassiri,Ezatodin Javadian
Zahedan Journal of Research in Medical Sciences , 2012,
Abstract: Background: Leishmaniasis is one of the main health problems in Iran. The purpose of this study was to determine species composition, sex ratio and relative abundance of sandfliesas vectors of cutaneous leishmaniasis.Materials and Methods: This cross-sectional study was conducted in Chabahar, Iran. Sandflies were caught using sticky traps. Traps were installed in 21 rural and urban areas.Results: A total of 17859 sandflieswere caught. Species caught including Phlebotomus papatasi Scopoli, P. salehi Mesghali, P. sergenti Parrot, P. alexandri Sinton, P. kazeruni Theodor and Mesghali, P. bergeroti Parrot, P. mesghali Seyedi-Rashti and Nadim, P. elaenorae Sinton, Sergentomyia clydei Sinton, S. sintoni Pringle, S. tiberiadis Adler, Theodor and Lourie, S. baghdadis Adler and Theodor , S. hodgsoni Sinton, S. dentate Sinton, S. africana Newstead, S. dreyfussi Theodor and Mesghali, S. mervynae Pringle, S. iranica Lewis and Mesghali and S. christophersi Sinton. Seven species, including P. elaenorae, P. kazeruni, S. hodgsoni, S. dreyfussi, S. mervynae, S. iranica and S. christophersi are reported for the first time in Chabahar.Conclusion: P. papatasi and P. salehi respectively play the role of primary and secondary vectors of cutaneous leishmaniasis in Chabahar city, due to their high abundance, presence in all the monthly activities, presence in all areas affected with oriental sore and finding leptomonad infection in them.
The Relationship between Perceived Organizational Justice and OCBs with Consider Moderating Role of Equity Sensitivity: Some Cultural Implications
Mohesn Golparvar,Zahra Javadian
International Journal of Psychological Studies , 2012, DOI: 10.5539/ijps.v4n2p28
Abstract: Perceived organizational justice is an important factor for prediction of various aspects of OCBs. This research investigates the extent to which equity sensitivity moderates the relationship between perceived organizational justice and OCBs. It was hypothesized that distributive, procedural, informational and interpersonal justice are related to OCBs (helping behavior, civic virtue, and sportsmanship) and equity sensitivity has been moderate these relationships. Research sample group were 123 employees of a petrochemical company in Iran. The moderated hierarchical regression analysis indicated that equity sensitivity moderates the relationship between perceived distributive organizational justice with civic virtue and sportsmanship. That is, in entitled group (and no in equity sensitive or benevolent groups) distributive justice positively and significantly related to civic virtue and sportsmanship (P<0.05). Also results indicated that equity sensitivity moderates the relationship between perceived procedural organizational justice and sportsmanship. That is, in an equity sensitive group (and no in entitled or benevolent groups) procedural justice positively and significantly related to sportsmanship (P<0.05).
Analysis of Spermatogenesis and CREM Gene Expression in Testis of Rat Treated with Matricaria recutita
Fereshteh Javadian,Jasem Estakhr
British Journal of Pharmacology and Toxicology , 2012,
Abstract: Camp-Responsive Element Modulator (CREM) is a key factor in the regulation of the expression of number of post-meiotic genes during spermatogenesis. Matricaria recutita shows different pharmacological activities like anti-inflammatory, anti-cancer, treatment of stress and depression, anti-allergic and etc. The objectives of this study are to investigate effects of Matricaria recutita on spermatogenesis and CREM expression at MRNA level. Animals were divided into 3 groups with 7 rats in each. The extract administered orally in the doses 100 and 150 mg/kg/day to rats for 56 consecutive days. Sperm analysis and RT-PCR were carried out to investigate rat reproductive function. Results indicated significant decrease in the epididymal sperm counts and sperm motility of experimental groups compared to control group. Reverse Transcription Polymerase Chain Reaction (RT-PCR) showed a decrease in the expression of CREM in the testes of experimental groups. From the data it can be concluded that Matricaria recutita has anti-spermatogenic properties.
Heuristic Approaches for Cell Formation in Cellular Manufacturing  [PDF]
Shahram Saeedi, Maghsud Solimanpur, Iraj Mahdavi, Nikbakhsh Javadian
Journal of Software Engineering and Applications (JSEA) , 2010, DOI: 10.4236/jsea.2010.37077
Abstract: Cellular Manufacturing System (CMS) is an application of Group Technology (GT) that allows decomposing a manu-facturing system into subsystems. Grouping the machines and parts in a cellular manufacturing system, based on simi-larities is known as cell formation problem (CFP) which is an NP-hard problem. In this paper, a mathematical model is proposed for CFP and is solved using the Ant Colony Optimization (ACO), Genetic Algorithm (GA) and Simulated Annealing (SA) meta-heuristic methods and the results are compared. The computational results show that the GA method is more effective in solving the model.
A New and Efficient Method for the Synthesis of Pyrimido[2,1-b]Benzothiazole Derivatives  [PDF]
Fatemeh Chadegani, Fatemeh Darviche, Saeed Balalaie
International Journal of Organic Chemistry (IJOC) , 2012, DOI: 10.4236/ijoc.2012.21006
Abstract: The one-pot three-component reaction of 2-aminobenzothiazole, benzaldehyde derivatives and β-ketoester, β-diketone or malonate derivatives in solvent-free conditions provides the corresponding pyrimido [2,1-b] benzothiazole derivatives at 60?C in 60% - 72% yields without using any catalyst in an optimistic time.
Y.Rassi,E. Javadian
Iranian Journal of Public Health , 1998,
Abstract: This study was carried out on Phlebotomus kandelakii and Ph.perfiliewi, the probable vectors of visceral leishmaniosis in the north west of Iran during the summer of 1994. The results of the susceptibility test showed that the mortality rate with 60-min exposure to 4% DDT was 100% for each species, while with 30-min exposure the average mortality rates were 93.3% and 94.4% for P. Kandelakii and P.perfiliewi, respectively, indicating the sensitivity of the two probable vectors to DDT in Ardabil Province. The blood meals of 116 engorged sand-flies were collected from 3 villages of Meshkin-shahr County, including P.papatasi, P.caucasicus and P. kandelaki, and eighty one of them belonged to P. kandelakii. All of the blood meals were positive with human and 11.1% with dog antisera, indicating a strong preference to man.
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