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Search Results: 1 - 10 of 8290 matches for " Farzana Ahmad Deen "
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Genesis of Polio Vaccination Hindrance Syndrome in Pakistani Society, Religio-Medical Aspects  [PDF]
Sadia Fida Ullah, Farzana Ahmad Deen, Yawar Hussain
Open Journal of Social Sciences (JSS) , 2016, DOI: 10.4236/jss.2016.43015
Abstract: Polio vaccination in Pakistan has received strong reaction from the society. Many reasons have been documented in literature to explain the causes of this issue. The present study is focused on the analysis of anatomy of genesis of Polio Vaccination Hindrance Syndrome (PVHS) in the light of Quranic Verses, Hadiths (saying of Prophet) and their interpretations done by the Muslim clerics at weekly sermons (Khotbat). Along with religious explanation, the medical aspects of vaccination are also taken under consideration. It is concluded from this analysis that Islam does not resist from Polio Vaccination and related medication. The real problem lies in the perception of vaccination as an attempt to genocide Muslims, coupled with lack of interests in international agencies.
Varietal Reaction of Cucumber against Cucumber mosaic virus  [PDF]
Asma Akbar, Zahoor Ahmad, Farzana Begum,   Ubairah, Neelam Raees
American Journal of Plant Sciences (AJPS) , 2015, DOI: 10.4236/ajps.2015.67090
Abstract: Family Cucurbitaceae is primarily found in the warmer regions of the world. It is the major family for economically important species, particularly edible fruits. In Pakistan cucurbits occupies an area of 28,600 ha with a very low production in Khyber Pukhtunkhwa due to many biotic and abiotic stresses. The reason is also the lack of growers’ awareness about the diseases and the cultural practices adopted to provide favorable environment for development of epidemics. Viral diseases such as Cucumber mosaic virus (CMV) cause losses as high as 100%. Various control strategies are being used to control CMV. The aim of the current study was to screen out different verities and to find the most resistant one against CMV. CMV isolate was collected from farmer’s field at the site of TaruJaba during a survey of cucurbit crops. The identity of the virus was confirmed through DAS-ELISA using diagnostic kit (ADGEN, UK). Seventeen cucumber germplasm seeds were sown in earthen pots in which fourteen were germinated and exhibited characteristics symptoms of the virus while none of them showed resistance against CMV. Symptoms’ expression was delayed in summer green and local green till 12 days post inoculation. While in khyber, Diamond, VEGAF1 and Yousaf, symptoms started to appear soon after inoculation categorizing them as highly susceptible. No resistance is found in available commercial germplasm, so more germplasm from different area of Pakistan should be tested for resistance against CMV. If no resistance is found locally imported, germplasm can be evaluated for a source of resistance against the prevalent isolates of CMV.
Development of a Risk Model for Abdominal Wound Dehiscence  [PDF]
Mujahid Ahmad Mir, Farzana Manzoor, Balvinder Singh, Imtiyaz Ahmad Sofi, Abu Zaved Rameez, Sheikh Imran Farooq
Surgical Science (SS) , 2016, DOI: 10.4236/ss.2016.710063
Abstract: Objectives: To identify independent risk factors for abdominal wound dehiscence and develop a risk model to recognize high risk patients. Methods: The samples studied were patients who underwent midline laparotomy in the department of surgery, SMHS Hospital Srinagar from March 2009 to April 2015. For each case of abdominal wound dehiscence, three controls were selected from a group of patients who had undergone open abdominal surgery as close as possible in time. Preoperative, perioperative, and postoperative variables and in-hospital mortality were studied for all patients. Cases were compared with controls using the chi-square test or the Mann-Whitney U-test for categorical or continuous data, respectively. Subsequently, multivariate stepwise logistic regression with backwards elimination test used to identify main independent risk factors of abdominal wound dehiscence. The resulting regression coefficients for the major risk factors were used as weights for these variables to calculate a risk score for abdominal wound dehiscence. Results: 140 cases of abdominal wound dehiscence were reported and compared with 420 selected controls. All variables that were significant in univariate analyses were entered in a multivariate stepwise logistic regression to determine which variables were significant independent risk factors. Major independent risk factors were male gender, chronic pulmonary disease, corticosteroid use, smoking, obesity, anemia, jaundice, ascites, and sepsis, type of surgery, postoperative coughing, and wound infection. Based on these findings, a risk model was developed. Conclusions: The model can give an estimate of the risk of abdominal wound dehiscence for individual patients. High-risk patients may be planned preventive wound closing with reinforcements as mesh.
Surface Water Suitability for Drinking Purpose in Cholistan Desert
Imtiaz Ahmad,Makshoof Athar,Farzana Sarwar
Journal of Biological Sciences , 2004,
Abstract: The desert dwellers in Cholistan desert use surface water collected in natural depressions or dugout ponds `Tobas` since the groundwater is brackish and not fit for human consumption especially for drinking purpose. The present study was conducted in cholistan desert to evaluate the quality of rainwater harvested in low lying areas or dugout ponds the only source of drinking water for humans as well as their livestock. Water samples were collected from 10 tobas of lesser Cholistan since most of the tobas were dried up due to the drought conditions. These samples were analyzed to quantify different parameters i.e. pH, HT, TDS, Alkalinity, Ca, Mg, Na, K, Fe, Zn, Cd, Cr, Cu, Sr, Ni, Pb, Co, Cl, PO4, SO4, CO3--, HCO3- and NO3 relating the water quality. The results showed that most of the parameters were found within the WHO recommended levels determining the suitability of this water for drinking purpose. However, Chemical Oxygen Demand (COD) concentration was found high indicating undesirable presence of organic matter. Higher concentration of Sr was found demanding future detailed study of drinking water in Cholistan.
High Protein Diet that Cause Weight Loss and Lower Blood Glucose Level Have a Serious Impact on the Kidney Functions of Male Diabetic Obese Albino Rats  [PDF]
Ahmed El-Sayed Nour El-Deen, Abd El-Megeed Mansour, Ahmad Taha
Food and Nutrition Sciences (FNS) , 2018, DOI: 10.4236/fns.2018.910085
Abstract: Background: High protein (HP) diets are increasingly being recommended as one of the management strategies for weight control in overweight and obese individuals. The health benefits of high protein diets are well-established, but the mechanisms of action on body systems responsible for the changes in body weight and glycaemic control are not well-clear. Objective: The present study aimed to examine the effect of HP diets on the kidney functions of diabetic obese albino rats. Material and Methods: Eighty male adult male albino rats were used in this study. The animals were divided into eight equal groups (10 rats for each). Type 2 DM and obesity were induced. At the end of the 12 weeks, samples were collected for biochemical analysis. Results: The high protein diet led to significant decrease in BW, FI, BG, TC, LDL, TG, Lactate dehydrogenase, albumin, urine pH and urine citrate; while serum insulin, HDL, urea, creatinine, total protein, urine volume and urinary excretion of Ca were significantly higher in high protein diet groups. Conclusion: A high protein intake in diabetic obese albino rats for 12 weeks led to changes in the serum and urine levels of markers of renal function which indicated abnormalities in the functions of the kidney.
Effect of Green Coffee on Cisplatin Induced Renal Apoptosis in Adult Male Albino Rats  [PDF]
Ahmed El-Sayed Nour El-Deen, Abd El-Megeed Mansour, Ahmad Taha, Ehab M. Fahmy
Food and Nutrition Sciences (FNS) , 2019, DOI: 10.4236/fns.2019.104028
Abstract: Background: Green coffee as a functional food has an antioxidant effect, which can reduce the cancer incidence, promote weight-loss and improve glucose and lipid metabolism, as well as anti-oxidant and anti-inflammatory activity. Objective: Assessing the effect of green coffee administration on experimental cisplatin induced renal apoptosis in adult male albino rats of local strain. Design: Randomized Block Design was used. Materials and Methods: Forty adult male albino rats of local strain were randomly divided into four groups of 10 animals each. G1: control negative group was received isotonic saline (0.5 ml, i.p.) for 30 consecutive days, G2: sham operated group mice were received green coffee extract in water (40 mg/kg/day) for 30 consecutive days, animals of G3 and G4 were administered cisplatin (8 mg/kg/day, i.p.) at 10th day, which is well known to produce significant nephrotoxicity in rats. Animals in G3 were received green coffee extract in water (40 mg/kg/day) and G4 was received isotonic normal saline (0.5 ml, i.p.) for 30 consecutive days. All rats were sacrificed after 30 days and blood was withdrawn for biochemical examinations of kidney function tests (blood urea nitrogen, creatinine and uric acid). Kidneys were removed for determination of renal oxidative stress markers (H2O2) biochemically and caspase-3 by Immunohistochemical examination. Results: Cisplatin administration was associated with significant higher levels of BUN, creatinine, uric acid and H2O2 as compared with normal control group. Green coffee administration in cisplatin-induced renal apoptosis groups produced significant lower levels of BUN, creatinine, uric acid and H2O2 (24.4 ± 4.14, 1.730 ± 0.2830, 5.50 ± 0.850 and 0.51 ± 0.12 respectively) as compared with cisplatin-induced renal apoptosis group not administrated green coffee (27.4 ± 6, 2.04 ± .31, 7.00 ± 1.25 and 1.1 ± 0.16 respectively). Cisplatin administration increased expression of the apoptotic protein caspase-3. In contrast, treatment with green coffee extract attenuated apoptosis. Conclusion: green coffee reduced cisplatin-induced renal apoptosis. Green coffee improved the general condition of cisplatin-induced renal apoptosis rats due to its antioxidant and anti-apoptotic effects.
Typhidot M and Diazo test vis-à-vis blood culture and Widal test in the early diagnosis of typhoid fever in children in a resource poor setting
Beig, Farzana K;Ahmad, Faraz;Ekram, Mohd;Shukla, Indu;
Brazilian Journal of Infectious Diseases , 2010, DOI: 10.1590/S1413-86702010000600007
Abstract: objective: typhoid fever is a major public health problem. a test which is simple, reliable and can be carried out in small laboratories is the need of the hour. we prospectively evaluated typhidot m and diazo tests vis-à-vis blood culture and widal test in children. methods: patients aged 6 months to 12 years, having fever of more than four days duration with clinical suspicion of typhoid fever were enrolled. patients in whom other diagnosis was made served as control. the tests under scrutiny were validated against blood culture and then all the four tests were evaluated among patients who presented in the first week of illness. results: blood culture was positive in only 27.3% of the cases. among these culture positive cases, typhidot m test had the highest sensitivity, specificity, ppv and npv of 90% (95% ci = 74.4-96.5), 100% (95% ci = 90.1-100), 100% (95% ci = 87.5-100), and 92.1% (95% ci = 79.2-97.3) respectively. diazo test ranked next with sensitivity, specificity, ppv and npv of 86.7% (95% ci = 70.3-94.7), 85.7% (95% ci = 70.6-93.7), 83.9% (95% ci = 67.4-92.9), 88.2% (95% ci = 73.4-95.3) respectively. among clinically suspected typhoid cases, the overall sensitivity, of blood culture, widal, typhidot m, diazo was 27.3% (95% ci = 19.8- 36.3), 64.6% (95% ci = 55.3-72.9), 89.1% (95% ci = 81.9-93.7), 80.9% (95% ci = 72.6-87.2) respectively. in the first week of illness, typhidot m showed the best sensitivity [86.2% (95% ci = 69.4-94.5)] followed by diazo [79% (95% ci = 61.6-90.2)], widal [41.4% (95% ci = 25.5-59.3)] and blood culture [31% (95% ci = 17.3-49.2)]. conclusion: both typhidot m and diazo are good screening tests for the diagnosis of typhoid fever. typhidot m is superior to diazo but the latter is more suitable to resource poor settings being economic and easy to perform.
Toward Integrated Clinical and Gene- Expression Profiles For Breast Cancer Prognosis: A Review Paper
Farzana Kabir Ahmad,Safaai Deris,Nor Hayati Othman
International Journal of Biometric and Bioinformatics , 2009,
Abstract: Breast cancer patients with the same diagnostic and clinical prognostics profilecan have markedly different clinical outcomes. This difference is possibly causedby the limitation of current breast cancer prognostic indices, which groupmolecularly distinct patients into similar clinical classes based mainly on themorphology of diseases. Traditional clinical-based prognosis models werediscovered to contain some restrictions to address the heterogeneity of breastcancer. The invention of microarray technology and its ability to simultaneouslyinterrogate thousands of genes has changed the paradigm of molecularclassification of human cancers as well as shifting clinical prognosis models to abroader prospect. Numerous studies have revealed the potential value of geneexpressionsignatures in examining the risk of disease recurrence. However,most of these studies attempted to implement genetic-marker based prognosticmodels to replace the traditional clinical markers, yet neglecting the richinformation contained in clinical information. Therefore, this research took theeffort to integrate both clinical and microarray data in order to obtain accuratebreast cancer prognosis, by taking into account that these data complement eachother. This article presents a review of the development of breast cancerprognosis models, concentrating precisely on clinical and gene-expressionprofiles. The literature is reviewed in an explicit machine-learning framework,which includes the elements of feature selection and classification techniques.
Biology and distribution of butterfly fauna of Hazara University, Garden Campus, Mansehra, Pakistan  [PDF]
Farzana Perveen, Fatima Fazal
Open Journal of Animal Sciences (OJAS) , 2013, DOI: 10.4236/ojas.2013.32A004
Abstract: The butterflies are beautiful creature of nature with great economic importance as pollinator as well as bio-indicator of environments. The present survey was conducted to determine the biology and distribution of butterfly fauna of Hazara University, Garden Campus, Mansehra, Pakistan during March-June 2012. The study area was divided into 3 quadrates, i.e., residential area, administration area and main campus. A total of 170 specimens were collected, 10 species were identified belonging to 3 different families and falling in 8 genera. The species were identified. The painted lady, Cynthia cardui (Linnaeus); blue pansy, Junonia orithya Linnaeus; and plain tiger, Danaus chrysippus (Linnaeus) were belonging to family Nymphalidae. The lime butterfly, Papilio demoleus Linnaeus and com-mon mormon, P. polytes Linnaeus were belonging to family Papilionidae. The dark clouded yellow, Colias croceus (Geoffroy); common grass yellow, Eumera hecab (Linnaeus); Murree green-veined white, Pieris ajaka Moore; green-veined white, P. napi (Linnaeus) and Bath white, Pontia daplidice (Linnaeus) were belonging to family Pieridae. The body sizes of E. hecabe and J. orithya were minimum, i.e.
Characterization of insect-fauna of the free-ranging urban dog, Canis domesticus (L.) carcass in tropical region of Pakistan: A tool for forensic entomology  [PDF]
Farzana Perveen, Anzela Khan
Advances in Entomology (AE) , 2013, DOI: 10.4236/ae.2013.12007
Abstract: As the authors’ request, the following paper published in Vol.1, No.2, 29-37, 2013 has been withdrawn from the website.
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