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Search Results: 1 - 10 of 219734 matches for " F. I. Mbutiwi "
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The Atherogenic Dyslipidemia Ratio Log (Tg)/Hdl-C Was Not Associated with Urinary Albumin Excretion Rate (Uaer) and Increased Cardiovascular Risk in Black Patients with Type 2 Diabetes  [PDF]
M. F. Kajingulu, B. F. Lepira, I. N. F. Mbutiwi, J. R. R. Makulo, E. Bieleli, M. N. Nseka
World Journal of Cardiovascular Diseases (WJCD) , 2016, DOI: 10.4236/wjcd.2016.61003
Abstract: Objective: The objective is to assess the relationship of Log (TG)/HDL-c as surrogate estimate of atherogenic dyslipidemia with urinary albumin excretion rate and cardiovascular risk among black patients with type 2 diabetes. Patients and methods: A post-hoc analysis of data from 181 type 2 diabetes patients enrolled in a cross-sectional study of urinary albumin excretion rate seen at a tertiary healthcare. Microalbuminuria and macroalbuminuria were defined as ACR 30 - 299.9 mg/g and ACR ≥ 300 mg/g, respectively. Quartiles of Log (TG)/HDL-c were used as surrogate estimates of atherogenic dyslipidemia. Cardiovascular risk was assessed using WHO chart for estimation of CV risk in low and middle income countries. Comparisons across Log (TG)/HDL-c quartiles were performed using one way ANOVA and Chi square for trend as appropriate. P < 0.05 defined the level of statistical significance. Results: A high prevalence (69%) of atherogenic dyslipidemia (AD) was observed in the present case series of Black Africans with type 2 diabetes. Average total cholesterol levels showed significant (p = 0.010) trends towards lower values across quartiles of Log (TG)/ HDL-c. No significant trends were observed for average UAER and cardiovascular risk across quartiles of Log (TG)/HDL-c. Conclusion: Log (TG)/HDL-c as a surrogate estimate of atherogenic failed to predict cardiovascular risk in the present case series of black patients with type 2 diabetes.
Left Ventricular Structure, Geometry and Systolic Function among Hypertensive Black Patients with Reduced Kidney Function  [PDF]
B. C. Mpembe, F. B. Lepira, F. I. Mbutiwi, J. R. Makulo, E. V. Kintoki, M. P. Bayauli, J. R. M’Buyamba-Kabangu
World Journal of Cardiovascular Diseases (WJCD) , 2015, DOI: 10.4236/wjcd.2015.510032
Abstract: Objective: To assess the LV mass, geometry and systolic function in hypertensive patients with reduced kidney function. Methods: According to ASE guidelines, we estimated LV ventricular mass, geometry and systolic function in 155 consecutive hypertensive patients [51% women, mean age 51 ± 12 years, median duration of hypertension 7 years] with reduced kidney function (eGFR < 60 ml/min/1.73 m2 or dipstick proteinuria ≥ 1+). LVH was defined as LVMI >125 g/m2 in men, >110 g/m2 in non obese women or >51 g/m2.7 for obese men or women. Where appropriate, we used Student t, Mann Whitney, one way ANOVA or Chi square tests. A P value of 0.05 or less was considered significant. Results: Seventy four patients in the series (48%) had reduced kidney function (eGFR 30 ± 15 ml/min/1.73 m2). Compared to patients with relatively normal kidney function, non obese and obese patients with reduced kidney function had significantly greater LVM [271 (198 - 348) vs 276 (175 - 284) g/m2, p = 0.008] for non obese; LVM 72 (47 - 88) vs 54 (44 - 73) g/m2.7, p = 0.007 for obese] and lower EF (60 ± 14 vs 68 ± 13%, p < 0.001) was significantly lower. LVH of mainly concentric geometric pattern was present in 68 patients with reduced kidney function (92%). Conclusion: In the present case series, reduced kidney function was associated with increased LVM, concentric geometric pattern and impaired systolic function.
Sickle Cell Trait, Hemoglobin Levels and Anemia among Black Patients with Predialysis Chronic Kidney Disease: A Post Hoc Analysis  [PDF]
F. B. Lepira, T. K. Mukendi, F. I. N. Mbutiwi, J. R. Makulo, E. K. Sumaili, P. K. Kayembe, N. M. Nseka
World Journal of Cardiovascular Diseases (WJCD) , 2016, DOI: 10.4236/wjcd.2016.68029
Abstract: Objective: To assess the relationship between SCT, hemoglobin levels and anemia in CKD black patients. Method: A post-hoc analysis of data from 188 patients, enrolled in a cross-sectional study of sickle cell trait (SCT) and chronic kidney disease (CKD), was performed to assess the relationship between SCT, hemoglobin (Hb) levels and anemia defined as Hb < 12 g/dl in men and <11 g/dl in women. Student t test, Mann Whitney and Chi square test were used as appropriate for different comparisons. P < 0.05 defined the level of statistical significance. Results: SCT (HbAS) and normal hemoglobin (HbAA) were present in 39 (21%) and 149 (79%) CKD patients, respectively. Despite similar estimated GFR (eGFR) and age, HbAS patients had significantly lower Hb levels (8.8 ± 1.8 vs 10 ± 2.2 g/dl; p = 0.001) and a higher proportion of anemia (95% vs 72%, p = 0.001). In multiple linear regression analysis, eGFR, BMI, SBP and SCT emerged as independent determinants of Hb levels. The presence of SCT was associated with 1.185 g/dl decrease in Hb levels. Conclusion: In the present case series, SCT was associated with lower Hb levels suggesting its potential contribution to the pathogenesis of CKD-associated anemia.
Comparison of the Performance of Three Commonly Used Electrocardiographic Indexes for the Diagnosis of Left Ventricular Hypertrophy in Black Hypertensive Patients with Reduced Kidney Function Managed at a Tertiary Healthcare Hospital: A Post-Hoc Analysis  [PDF]
F. B. Lepira, C. M. B. Mpembe, F. I. N. Mbutiwi, J. R. Makulo, P. K. Kayembe, F. M. Kajingulu, E. V. Kintoki, J. R. M’buyamba-Kabangu
World Journal of Cardiovascular Diseases (WJCD) , 2017, DOI: 10.4236/wjcd.2017.74011
Background: Reduced kidney function in blacks is associated with an increased frequency of left ventricular hypertrophy. Given the unavailability of echocardiography in most developing countries, the diagnostic performance of current ECG indexes needs to be evaluated. Objective: To compare the diagnostic performance of 3 commonly used ECG indexes (Sokolow-Lyon, Cornell voltage and Cornell product) in black hypertensive patients. Methods: Electrocardiography and echocardiography estimated left ventricular mass of 155 consecutive hypertensive patients who participated from January 2012 to January 2013 to an echocardiographic cross-sectional study of left ventricular structure was analyzed to compare Cornell voltage and Cornell product indexes with Sokolow-Lyon voltage index as a reference. Reduced kidney function was defined as eGFR < 60 ml/min/1.730.05 m2. ROC curves in relation to LVH diagnosis were used to estimate the sensitivities and specificities of each index. P < 0.05 defined the level of the statistical significance. Results: The sensitivity and specificity were 43% and 85%, 23% and 77% and 26% and 77% for Sokolow-Lyon, Cornell voltage and Cornell product indexes, respectively. However, Sokolow-Lyon index (AUC; 95% CI: 0.64; 0.50 - 0.78) showed better performance than Cornell voltage (0.42; 0.25 - 0.59) and Cornell product (0.43; 0.28 - 0.59). Sokolow-Lyon index cut-point ≥ 37 mm corresponded to the highest Youden index (39.4% of sensitivity and 92.3% of specificity). Conclusion: Although the overall performance of the 3 ECG indexes versus echocardiography was low, Sokolow-Lyon index performed better than the two other indexes in diagnosing LVH.
Measuring Mass and Spin of Dark Matter Particles with the Aid Energy Spectra of Single Lepton and Dijet at the e+e- Linear Collider  [PDF]
I. F. Ginzburg
Journal of Modern Physics (JMP) , 2014, DOI: 10.4236/jmp.2014.511105

In many models stability of Dark Matter particles D is ensured by conservation of a new quantum number referred to as D -parity. Our models also contain charged D -odd particles D± with the same spin as D. (For more information,please refer to the PDF.)

An engineered Phlebia radiata manganese peroxidase: expression, refolding, purification and preliminary characterization  [PDF]
Usenobong F. Ufot, Monday I. Akpanabiatu
American Journal of Molecular Biology (AJMB) , 2012, DOI: 10.4236/ajmb.2012.24037
Abstract: Manganese peroxidases (MnPs) are interesting enzymes in protein engineering, aimed at maximizing industrial bioprocesses such as lignin degradation and biofuel production. cDNA of the secreted short-type of MnP from Phlebia radiata (Pr-MnP3) has been successfully engineered and amplified by polymerase chain reaction (PCR). Five mutant genes (E40H, E44H, E40H/E44H, D186H and D186N) of recombinant Phlebia radiata MnP3 (rPr-MnP3) were generated. The wild-type and the mutant genes were expressed in Escherichia coli (W3110 strain) and the resultant body proteins were lysed, purified and refolded into active enzymes. 6% - 7% recovery of pure and fully active rPr-MnP3 for wild-type and mutants were obtained and the availability of rPr-MnP3 enzymes will greatly facilitate its structure-function relationships studies. rPr-MnP3 mass was characterised using SDS-PAGE and MALDI-TOF mass spectrometry. Molecular weight of both the wild-type and mutant rPr-MnP3 enzymes was approximately 36 kDa. This describes the spectral characterization of the wild-type and mutant rPr-MnP3 enzymes with are very close similarities; substantially high spin haem enzymes. Therefore we report the engineering, cloning, expression, refolding/activation of MnP3 genes and preliminary characterization of the wild-type and mutant Phlebia radiata MnP3 enzymes.
Effect of Tillage Systems and Vine Orientation on Yield of Sweet Potato (Ipomoea batatas L.)  [PDF]
I. Chagonda, R. F. Mapfeka, T. Chitata
American Journal of Plant Sciences (AJPS) , 2014, DOI: 10.4236/ajps.2014.521332
Abstract: In Zimbabwe sweet potato (Ipomoea batatas L.) production is practiced under different tillage systems with varying vine orientations, which contribute to variable yields. Limited research on yield loss due to these different practices is available despite that the majority of farmers are growing sweet potatoes to sustain their livelihoods. A field study was carried out at Midlands State University in the 2013/14 rainy season, to determine the effect of tillage systems and vine orientation on yield of sweet potato. A 2 × 3 factorial treatment structure in a randomized complete block design (RCBD), with three replications was used. Tillage systems had two factors (ridge and mound) and three vine orientations were used (horizontal, fold and loop). Data on storage root length, storage root diameter and storage root weight was subjected to Analysis of Variance (ANOVA) at 5% significance level. There was no interaction (p < 0.05) between tillage systems and vine orientations on storage root diameter, storage root length and storage root yield. The horizontal vine orientation gave statistically significant (p < 0.05) storage roots diameter of width 405 mm. Conversely the loop vine orientation had statistically the least (316 mm) storage root diameter. Horizontal vine orientation had significantly (p < 0.05) wider storage roots than the loop vine orientation. The ridge recorded longer (134.2 mm) mean storage root length, while those from mounds had shorter (115.9 mm) root length. The loop and the horizontal vine orientations recorded statistically the highest (35.5 t/ha and 34.8 t/ha respectively) sweet potato storage root yield. On the other hand, the fold vine orientation obtained significantly the lowest (28.7 t/ha) storage root yield. The research concluded that the horizontal and fold vine orientations had the widest storage root diameter and the ridge had longer storage root lengths. The loop and horizontal vine orientations are recommended in sweet potato production if high yields are to be achieved.
Modeling of Plane Arrays Using a Variational Approach  [PDF]
Mykhaylo I. Andriychuk, Yarema F. Kuleshnyk
Open Journal of Antennas and Propagation (OJAPr) , 2018, DOI: 10.4236/ojapr.2018.64009
The variational statement of synthesis problem is generalized in order to account the additional requirements to the synthesized radiation pattern (RP) and field distribution in the specified points of near zone. For this aim, the minimizing functional is supplemented by term providing the possibility to minimize the values of field in these points; creating the deep zeros in the RP for the certain angular coordinates is realized too. The approach foresees reduction of an explicit formula for field values in a near zone. The results of computational modeling testify the possibility to create zeros in the given RP and to minimize the values of field in a near zone of plane arrays in a great extent.
Comparative Study of Physical Properties of Polymer Composites Reinforced with Uncarbonised and Carbonised Coir  [PDF]
F. O. Aguele, C. I. Madufor, K. F. Adekunle
Open Journal of Polymer Chemistry (OJPChem) , 2014, DOI: 10.4236/ojpchem.2014.43009

This study involved the use of uncarbonised and carbonised coir in preparing composites of a given polymer. In this case natural rubber (NR) was used. Uncarbonised coir (UC) and carbonised coir (CC) were separately used to prepare the polymer composites. Carbon black (CB) was also used differently and the filler loadings for all varied between 0 and 50 phr. Before using the uncarbonised coir and carbonised coir, they were characterised on the basis of moisture content, pH, particles size and surface area. The properties of the various composite samples prepared were then investigated. The results of the tests obtained for the NR-UC composites were compared with those of NR-CC and also with those of NR-CB composites. It was observed that for hardness, the results obtained from composites of UC and CC fillers showed similar trends with those of carbon black (CB) reinforced composites, increasing with increase in filler volume. For the tensile strength and modulus a trend of slight rise was observed. There were no sharp rises in values as filler volumes were increased. UC and CC fillers were observed to impart very poorly on the tensile strength and modulus relative to the CB reinforced composites. The results from test for elongation, compression set and flex fatigue showed a falling trend for all the fillers to a comparable level with CB. It was generally observed that the uncarbonised coir presented better potentials for reinforcement than the carbonised coir.

F. I. Pugnaire,F. Valladares
Web Ecology (WE) , 2006, DOI: 10.5194/we-6-1-2006
Abstract: No abstract available.
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