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Search Results: 1 - 10 of 144442 matches for " Félicité Kamdem "
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Epidemiologic Aspects of Atrial Fibrillation in a Tertiary Hospital in a Sub-Saharan Africa Setting  [PDF]
Félicité Kamdem, Ba Hamadou, Marius Kamdem, Christ Nadège Nganou, Anastase Dzudie, Yves Monkam, Samuel Kingue
Open Access Library Journal (OALib Journal) , 2017, DOI: 10.4236/oalib.1103384
Abstract:
Background: Atrial fibrillation (AF) is the most frequent sustained arrhythmia. The prevalence is increasing with that of other cardiovascular risk factors in our low-income setting. It is potentially serious due to the associated complications. Few data exist on the epidemiology of AF in Sub-Saharan Africa (SSA). Methodology: We carried out a cross-sectional study between 2005 and 2009 in the Cardiology Unit of the Douala General Hospital. Patients were adults ≥ 18 years of both sex, who had an ECG diagnosis of Atrial Fibrillation and a comprehensive investigation of the cause of AF. Results: A total of 2581 patients were seen in this unit, of whom 182 (7.1%, [95%: 6.1-8.1]) had AF. Their mean age was 59.2 ± 15.4 years, and there were 100 (58.2%, [95% CI: 51-65.6], p = 0.002) females. Hypertension was the most frequent risk factor (77.3%, [95% CI: 70.3-82.8]), and 163 (95.3%, [95% CI: 90.7-97.8]) of the patients were symptomatic. Hypertensive heart disease (45.6%, [95% CI: 38.3-53.1]), idiopathic dilated cardiomyopathy (19.3%, [95% CI: 14.1-25.9]), and valvular heart disease (16.4%, [95% CI: 11.6-22.6]) were the main etiologic factors of AF. The most frequent complications were heart failure seen in 77 (45%, [37.8-52.5]) and ischemic stroke in 27 (15.5%, [95% CI: 11.1 - 22]) of patients. Digoxine was prescribed in 121 (70.8%, [95% CI: 63.6-77.1]) patients to control heart rate, while amiodarone was prescribed in 67 (29.2%, [95% CI: 32.2-46.7]) patients to revert to sinus rhythm. No electrical cardioversion was carried out. Aspirine was prescribed in 119 (69.6%, [95% CI: 62.3-76]) patients, and anti-vitamin K in 53 (30.4%, [95% CI: 24.5-38.3]) patients. Conclusion: Atrial fibrillation was seen in seven percent of patients in the Cardiology Unit of this low-income setting. Patients were relatively young compared with high income settings. Hypertension, idiopathic dilated cardiomyopathy, and valvular heart disease were the main causes. Rate control was the main treatment strategy. Oral anti-coagulants were less frequently used.


Prevalence and Risk Factors of Peripheral Artery Disease in a Group of Apparently Healthy Young Cameroonians: A Cross-Sectional Study  [PDF]
Félicité Kamdem, Yacouba Njankouo Mapoure, Ba Hamadou, Fanny Souksouna, Ahmadou Musa Jingi, Caroline Kenmegne, Fernando Kemta Lekpa, Jaff Fenkeu Kweban, Gisèlei Mandy, Jean Pierre Nda Mefo’o, Henry Luma, Marie Solange Doualla
World Journal of Cardiovascular Diseases (WJCD) , 2018, DOI: 10.4236/wjcd.2018.82011
Abstract:
Background: The?burden of peripheral artery disease (PAD) is not well known among apparently healthy people in Africa. Aim: To determine the prevalence and associated risk factors of PAD in a group of blood donors seen at the Douala General HospitalCameroon. Methods: Between 1st November 2015 and 30th April 2016, we carried out a cross-sectional study. Participants were consenting adults of both sexes, aged ≥ 21 years who presented for blood donation, and were tested HIV negative. We collected socio-demographic data and their past history. We carried out a physical examination and measured their Ankle-Brachial Index (ABI). We defined PAD as an ABI < 0.9. We also measured their fasting blood glucose and lipid profile. Results: We recruited 103 participants, 55.4% males. The mean age was 33 ± 10 years. The mean ABI on left and right leg was 1.04 ± 0.1 and 1.02 ± 0.1respectively. ABI was higher in males than females both legs (p < 0.05). PAD was seen in 11 (10.7%) participants. This was higher in females than males (3.6% versus 19.2%, p = 0.026). Among those with PAD, 8 (72.7%) were asymptomatic (Males: 100% versus Females: 66%, p
Epidemiology, Clinical Presentations and In-Hospital Mortality of Venous Thromboembolism at the Douala General Hospital: A Cross-Sectional Study in Cameroon, Sub-Saharan Africa  [PDF]
Félicité Kamdem, Bertrand Hugo Mbatchou Ngahane, Ba Hamadou, Agborbessong Mongyui, Marie Solange Doualla, Ahmadou Musa Jingi, Anastase Dzudie, Yves Monkam, Henri Ngote, Sidick Mouliom, Caroline Kenmegne, Jaff Kweban Fenkeu, Romuald Hentchoya, Albert Kana, Aminata Coulibaly, Henry Luma
World Journal of Cardiovascular Diseases (WJCD) , 2018, DOI: 10.4236/wjcd.2018.82012
Abstract: Background: Venous thromboembolism (VTE) is a major cause of morbidity and mortality worldwide. It is also the most common complication in hospitalized patients. Aims:?To?study the in-hospital prevalence of VTE, describe the socio-demographic characteristics of patients, determine the frequency of risk factors, describe the clinical presentations, and determine the short term outcome of VTE in hospitalized patients in a low-income tertiary hospital setting.Methods: We carried out a cross-sectional descriptive retrospective study over a period of 6 years and 4 months (January 2008 to April 2014) in the Douala General HospitalCameroon. Patients were cases of confirmed venous thromboembolic disease (VTE).Results: A total of 78 case files were retained for this study, giving an in-hospital prevalence of 4.4 per 1000 admissions. There were 42 (53.8%) males and 36 (46.1%) females. Their ages ranged from 18 to 89 years (median: 53 years, [IQR: 40?-?61]).There were 37 (47.4%) cases of Deep Vein Thrombosis (DVT), 31 (39.7%) cases of Pulmonary Embolism (PE), and 10 (12.8%) cases of PE associated with DVT (12.8%). The main risk factors were obesity (44.9%), hypertension (37.2%), immobility (20.5%), and long-haul travel (17.9%). The most frequent clinical presentations in PE were dyspnea (80.5%) and chest pain (65.9%). There were 8 (10%) in-hospital deaths. Conclusion: About twelve cases of VTE are seen yearly at the DGH, with an in-hospital mortality of ten percent. Obesity and hypertension were the main risk factors, with dyspnea and chest pain being the main clinical manifestations in PE, and lower limb swelling the main symptom in DVT.
Effect of Therapeutic Group Education on Adherence and Blood Pressure Control among Uncontrolled Hypertensive Patients in Sub Saharan Africa  [PDF]
Chris Nadège Nganou-Gnindjio, Hélo?se Guidelle Kenmogne Domning, Liliane Mfeukeu-Kuate, Ba Hamadou, Félicité Kamdem, Georges Bediang, Aurel T. Tankeu, Alain Patrick Menanga, Samuel Kingue
World Journal of Cardiovascular Diseases (WJCD) , 2018, DOI: 10.4236/wjcd.2018.83018
Abstract: Background: Hypertension is the leading cardiovascular risk factor worldwide, with the greatest burden in low-income settings. Blood pressure (BP) control is usually low resulting in high rates of uncontrolled patients and complications. Low awareness resulting in poor therapeutic adherence represents an important factor for insufficient blood pressure control in developing countries. Methods: This was a three months non-randomized control trial at the cardiology clinic of the Yaoundé Central Hospital. We included adults with essential and uncontrolled hypertension. The intervention consisted of group educative sessions every week focusing on knowledge of hypertension risk factors, complications, treatment, comorbidities, home self-monitoring of BP. Home blood pressure figures, drug compliance, and knowledge regarding hypertension were evaluated before and after. Results: 17 participants (8 women) with a mean age 56.2 ± 8.1 years. During intervention, mean SBP decreased by 30 mmHg while mean DBP drooped by 11 mmHg using home BP measures. Knowledge regarding hypertension, adherence and drug compliance increased by 36.5%, 88.2% and 81.4% respectively. Conclusion: Therapeutic group education resulted in a significant improvement in BP control amongst uncontrolled hypertensive patients in sub Saharan Africa.
Epidemiology, Clinical and Paraclinical Presentations of Pulmonary Embolism: A Cross-Sectional Study in a Sub-Saharan Africa Setting  [PDF]
Bertrand Hugo Mbatchou Ngahane, Félicité Kamdem, Silvain Raoul Simeni Njonnou, Nina Chebou, Anastase Dzudie, Serge Arnold Ebongue, Bruno Tengang, Fernando Kemta Lekpa, Yacouba Mapoure Njankouo, Sidick Mouliom, Henri Roger Ngote, Henry Luma Namme
Open Journal of Respiratory Diseases (OJRD) , 2019, DOI: 10.4236/ojrd.2019.93008
Abstract: Background: Venous thromboembolic (VTE) disease burden is increasing worldwide, representing a major cause of cardiovascular death and public health problem. Pulmonary embolism (PE) is the most serious clinical presentation of VTE. Epidemiological and clinical data on PE are still lacking in Africa, particularly in Cameroon. This study aimed at determining the clinical features as well as imaging presentation and outcome of pulmonary embolism. Methods: A cross-sectional study was carried out in three hospitals in Douala. We retrospectively reviewed patient records admitted for PE from January 2009 to May 2017. We collected data on epidemiology, clinical presentation, venous Doppler/pulmonary computed tomographic angiography (CTA), and outcome. Results: We included 103 patients (56 males) with PE. Their median age was 52 years. The main risk factors were obesity (49.5%), hypertension (35.0%), long trip (24.3%) and cancer (18.4%). The most frequent clinical presentations were dyspnoea (83.4%), chest pain (78.6%), and cough (40.8%). Additionally, pleural effusion (32.8%), atelectasis (25.7%) and pulmonary hyperlucency (20.0%) were the most frequent findings on chest X-ray. The main abnormalities found in electrocardiogram were sinus tachycardia (63.4%), S1Q3T3 aspect (37.6%) and right axial deviation (28.7%). Moreover, right cavities dilatation (26.0%), pulmonary artery hypertension (35.0%) and pulmonary artery dilatation (21.0%) were the main echocardiographic findings. Low-molecular-weight heparin (LMWH) was the initial anticoagulant in all cases. There were 19 (18.4%) in-hospital deaths, and the mean hospital stay was 8.5 ± 5 days. Conclusion: PE is not rare in our setting. Obesity, long trip and cancer are the main risk factors, while dyspnoea, chest pain and respiratory distress are the main clinical presentation for PE. LMWH remains the therapeutic agent of choice. Lastly, in-hospital mortality is very high.
Land Use and Land Cover Change Analysis in Ajei Upland Watershed Community Forest, North West Region, Cameroon  [PDF]
Lucie Félicité Temgoua, Gordon Ajonina, Hans Berinyuy Woyu
Journal of Geoscience and Environment Protection (GEP) , 2018, DOI: 10.4236/gep.2018.69007
Abstract: This study was carried out in Ajei upland watershed community forest in the North West Region of Cameroon with the aim to analyze spatial and temporal dynamics of land cover and land use from 1988 to 2018 and to identify and characterize the agents, drivers and pressures of this change. The databases used were made up of 3 Lands at satellite images (5 TM of 1988, 7ETM+ of 2003 and 8OLI of 2018). Field survey, interview and focus group discussion methods were used to identify the activities carried out by the local population and to determine agents, drivers and pressures of land use and land cover change. The Ajei community forest is consisted of four main land cover namely; dense vegetation, sparse or degraded vegetation, savanna and bare soil. Between 1988 and 2018, the proportions of dense vegetation and savanna decreased and that of bare soil and sparse vegetation increased. Analysis showed ongoing deforestation with forest cover loss of about 240 ha in 30 years. For the considered time periods 1988-2003 and 2003-2018, deforestation rates were 1.83% per year and 1.49% per year respectively, signifying on average 8 hectares of forest cover undergoing conversion each year. This lost results from the actions of farmers, cattle grazers and wood extractors who through farming, grazing and lumbering activities pressurize and convert the dense forest cover. Economic motives notably the need to increase household income from a frequent demand for farm and wood products in nearby markets represent the drivers of forest cover change. Controlling grazing activities notably in the dry season to check out the use of fires, community sensitization especially among cattle headmen on the importance of the community forest, reforestation activities through natural regeneration or tree planting are needed in the forest.
Lipid Oxidation of Catfish (Arius maculatus) after Cooking and Smoking by Different Methods Applied in Cameroon  [PDF]
Noel Tenyang, Hilaire Macaire Womeni, Bernard Tiencheu, Nand Hrodrik Takugan Foka, Félicité Tchouanguep Mbiapo, Pierre Villeneuve, Michel Linder
Food and Nutrition Sciences (FNS) , 2013, DOI: 10.4236/fns.2013.49A1025
Abstract:

The influence of different cooking and smoking methods (boiling, frying, frying + boiling, hot and cold smoking) on oxidation and fatty acid composition of catfish (Arius maculatus) commercialized on the Wouri river coast was evaluated including commonly used analytical indexes (peroxide and acid values)and physical analysis by Fourier transform infrared (FTIR) spectroscopy. The mean moisture, protein, ash and fat contents of raw fish were 75.88 ± 0.55; 64.24 ± 0.14; 10.98 ± 0.31 and 23.02 ± 0.88 respectively. All these treatments provoke the modification of the quality indexes. Lipid deterioration, thermolysis and lipid oxidation occurred throughout the treatment. Peroxide value decreased for all cooked and smoked catfish, while free fatty acids of smoked sample increased. The FTIR applied to evaluate lipid oxidation in extracted lipid clearly provided a better picture of the oxidation progress and led to a similar conclusion with chemical analysis. Boiled, bleaching hot and bleaching cold smoking were found to be the suitable treatment methods for catfish because they gave it a high nutritive value compared to other smoking methods.

Prevalence and CT-Scan Presentations of Brain Malformations in Children at a University-Affiliated Mother and Child Hospital (Cameroon)  [PDF]
Boniface Moifo, Rosine Azegha Jiotsa, Seraphin Nguefack, Sandra Tatah, Evelyne Mah, Félicité Dongmo Nguefack, Elie Mbonda
Open Journal of Medical Imaging (OJMI) , 2017, DOI: 10.4236/ojmi.2017.74020
Abstract: Background: Brain malformations (BMs) are congenital abnormalities of the shape or structure of the brain, with corpus callosum agenesis known as the most frequent. Diagnosis of most BMs can be prenatal with ultrasound and fetal magnetic resonance imaging (MRI); post-natal diagnosis is based on transfontanellar ultrasound, CT-scan, and head MRI which is the imaging gold standard technique. MRI has been recently introduced and the CT-scan was previously the reference technique for the diagnosis of BMs in our context. Almost no publication has been made in sub-Saharan Africa on the clinical and CT scan characteristics of Brain malformations in children. Objective: The aim of this study was, in the absence of MRI, to describe the clinical and CT-scan presentations of brain malformations in children at the Yaounde Gynaeco-Obstetric and Pediatric Hospital (YGOPH). Patients and method: This was a cross-sectional descriptive study conducted from February to May 2016 at the YGOPH, including all children of 15-year-old and less with BM diagnosed on CT-scan at YGOPH between April 2006 and March 2016. The studied variables were clinical (age at diagnosis, sex, clinical manifestations) and CT findings (type of cerebral malformation). The data was analyzed using the SPSS 20.0 software with the estimation of hospital prevalence of BMs, frequencies and associations. The chi-square test was used to seek for an association between variables. The threshold of significance was p < 0.05. Results: The prevalence of BMs was 0.52%, with 29 cases of BMs identified out of 5590 patients followed up at the pediatric neurology outpatient unit over a period of 10 years. The mean age at diagnosis was 37.2 months (3.1 years) and the most represented age groups were 0 - 1 year (37.9%) and 1 - 5 years (37.9%). The sex ratio was 0.81 (55.2% girls). The clinical presentation was represented by neurological signs (93.1%) with convulsions (65.5%) and psychomotor retardation (58.8%) associated with skin lesions (34.5%) and/or facial dysmorphic features (27.6%). BM was suspected on antenatal ultrasound in 14.3% of cases (4/28). Abnormalities of cortical development accounted for 65.5% of BM followed by abnormalities of brain separation (31%). Tuberous sclerosis complex was the most common BM (31%) followed by agenesis of the corpus callosum (27.6%). The presence of dysmorphic facial features was associated (p = 0.007) with disorders of brain separation (DBS) while the presence of cutaneous lesions was
Spatio-Temporal Dynamic of Land Use and Land Cover in the Classified Forest of Djoli-Kera, South-Eastern, Chad  [PDF]
Lucie Félicité Temgoua, Behimnan Allaissem, Martin Tchamba, Goy Saradoum, Mbaiakambeye Mbaidje Osée, Marie Caroline Momo Solefack
Open Journal of Forestry (OJF) , 2018, DOI: 10.4236/ojf.2018.83019
Abstract: This study was carried out in the classified forest of Djoli-Kera found in the South-Eastern part of Chad. It aimed to analyze the spatial and temporal dy-namics of land cover between 1972 and 2013 and to determine the drivers of vegetation degradation. The databases used were made up of 4 Landsat satellite images (1MSS of 1972, 5TM of 1984, 7ETM+ of 1990 and 2010) and a spot 6 image of 2013, supplemented by field studies. Satellite images were processed using ENVI and ArcGIS software. Interview was used to identify the activities carried out by the local population. In 1972, the classified forest consisted of four types of land cover, the most important of which was open forest (51%), followed by wooded savannah (26%), tree savannah (21%) and sparse vegetation consisting of farms and fallows (2%). Gradually open forest and tree savannah disappeared. In 2013, the main types of land cover were shrub savannah (40%), sparse vegetation (28%), wooded savannah (12%), bare soil (12%) and dwellings (8%). Livestock, agriculture, wood collection and bushfires are perceived by local population as main drivers of forest cover change. Awareness-raising, monitoring and regulation of access to resources must be pursued, but also managers of the classified forest must accompany the local populations in the planting of trees and the setting up of more efficient farming systems to reduce pressure on the forest’s resources.
Aflatoxin Contamination in Food and Body Fluids in Relation to Malnutrition and Cancer Status in Cameroon
Angele N. Tchana,Paul F. Moundipa,Félicité M. Tchouanguep
International Journal of Environmental Research and Public Health , 2010, DOI: 10.3390/ijerph7010178
Abstract: Aflatoxins are food contaminants usually associated with hepatitis, immunodepression, impairment of fertility and cancer. The present work was to determine the presence of aflatoxins in eggs, milk, urine, and blood samples that were collected from various sources and periods; and hepatitis B virus antigen in blood samples. Aflatoxin was found in eggs (45.2%), cow raw milk (15.9%), breast milk (4.8%), urine from kwashiorkor and marasmic kwashiorkor children (45.5%), and sera from primary liver cancer patients (63.9%); HbsAg was also detected in 69.4% of the serum samples, but there was no association between both factors. Both AF and hepatitis B virus seem to be risk factors that could increase the incidence and prevalence rates of malnutrition and cancer in Cameroon.
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