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Search Results: 1 - 10 of 21574 matches for " Eun-Joo Kim "
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System and rapidity dependence of baryon to meson ratios at RHIC
Eun-Joo Kim
Physics , 2005,
Abstract: The rapidity and centrality dependence of baryon to meson ratios in Au$+$Au, Cu$+$Cu and p$+$p collisions at $\sqrt{s_{NN}}$ = 200 GeV at RHIC is presented. The $\bar{p}/\pi^{-}$ ratios are founded to be independent of collision system at a fixed $$ at mid- and forward rapidities.
Parton energy loss, saturation, and recombination at BRAHMS
Eun-Joo Kim
Physics , 2005,
Abstract: Particle production as observed with the BRAHMS experiment at RHIC is presented. Preliminary baryon/meson ratios and nuclear modification factors at different rapidities will be discussed.
Defense Mechanism and Optimism in Korean College Students  [PDF]
Eun-Joo Hong, Hyo-Eun Kim, Jin-Kyung Kim
Open Journal of Social Sciences (JSS) , 2014, DOI: 10.4236/jss.2014.211012
Abstract:

The objective of this study was to illustrate the relationship between optimism and defense mechanism in Korean college students. 332 student participants from “A” University in Korea completed questionnaires from the Ewah defense mechanism and optimism measurement tool. This study analyzed the culled data and revealed general patterns of optimism and defense mechanism, as well as patterns based on gender. In addition, the study analyzed differences in defense mechanism, dictated by one’s optimism level. Frequency, percentage, mean, standard deviation, and t-test were analyzed using SPSS 21.0. The results demonstrated that the operating defense mechanism in Korean college students were different for males and females in the categories of show-off, passive aggressive, denial, and identification. However, the level of optimism was identical for both genders. Defensive mechanisms based on optimism levels also varied significantly in controlling, distortion, altruism, humor, sublimation, and rationalization categories.

Parity Odd Domain Structure with Generalized $θ$ Vacuum
Eun-Joo Kim,Jong Bum Choi
Physics , 2013, DOI: 10.3938/jkps.64.495
Abstract: Recent experiments in heavy ion collisions have shown the possibility of creating parity-odd domains resulting from the $\theta$ term in strong interaction Lagrangian. The $\theta$ term originates from the nontrivial solution of QCD vacuum known as the $\theta$ vacuum, and the value of $\theta$ is taken to be a function of spacetime coordinates in the parity-odd domains. This means that we have to consider different theories at each point so that we need to devise a new approach to define the QCD vacuum. In this Letter, we suggest a method to generalize the $\theta$ vacuum by exploiting the dimension 2 condensates and to calculate the parity-odd domain structure as the union of gauge slices defined by the constant value of dimension 2 condensate.
Gluon Propagation in Curved Space
Su Kyeong Lee,Eun-Joo Kim,Jong Bum Choi
Physics , 2015,
Abstract: In quantum chromodynamics (QCD), the vacuum structures are taken to be formed by nonperturbative interactions between gluons. The contributions of gluonic interactions can be parametrized by gluon condensates and especially the dimension-2 condensate $\langle A_{\mu}^{2} \rangle$ can be used to generalize the $\theta$ vacuum. In the generalized picture, each gauge fixed slice forms a curved surface around a hadron and other strongly interacting objects, and the propagation of a gluon has to be considered on this curved surface. The gluon propagator turns out to be massive due to the curvature of the gauge fixed surface implementing the possibility that the massless gauge bosons might provide the majority of the hadronic mass and even behave as dark matter in cosmological scales.
Cognitive Profiles and Subtypes of Patients with Mild Cognitive Impairment: Data from a Clinical Follow-Up Study  [PDF]
Kyung Won Park, Eun-Joo Kim, Hwan Joo, Sung-Man Jeon, Seong-Ho Choi, Jay C. Kwon, Byoung Gwon Kim, Jae Woo Kim
International Journal of Clinical Medicine (IJCM) , 2012, DOI: 10.4236/ijcm.2012.35068
Abstract: Background: Mild cognitive impairment (MCI) is a heterogeneous condition with a variety of clinical outcomes, the presence of which correlates with risk of Alzheimer’s disease as well as pre-clinical stages of other dementia subtypes. The aims of this study were to assess the specific patterns of cognitive profiles and to identify changes from baseline to 24 weeks in patients with MCI using detailed neuropsychological testing. Methods: We consecutively recruited 120 MCI patients at baseline according to the Petersen’s clinical diagnostic criteria, who were admitted to the Dementia and Memory Clinics. We analyzed patients who fulfilled both inclusion and exclusion criteria for MCI and classified them into four subtypes according to deficits in major cognitive domains; amnestic MCI single domain (aMCI-s), amnestic multiple domain MCI (aMCI-m), non-amnestic single domain MCI (naMCI-s) and non-amnestic multiple domain MCI (naMCI-m). Four groups of MCI were evaluated by a detailed neuropsychological battery test. Results: 83 patients with MCI at the 24-week follow-up were classified into four subtypes. The most frequent subtype was amnestic multi-domain MCI, with the frequency of MCI subtypes as follows: aMCI-s (n = 21, 25.3%), aMCI-m (n = 53, 63.9%), naMCI-s (n = 5, 6.0%) and naMCI-m (n = 4, 4.8%). In the major cognitive items of the SNSB-D, there were significant changes between the initial and follow-up tests in the domains of language, memory and the fron-tal/executive function (p < 0.05), except for attention, in all MCI patient subtypes. At 24-weeks follow-up, the conversion rate to Alzheimer’s disease was 2.4% (n = 2) from a subtype of amnestic multi-domain MCI. Conclusions: Our study revealed the most frequent subtype of MCI to be multiple domain amnestic MCI, with this subtype having a higher tendency of conversion to Alzheimer’s disease.
Clinicopathologic significance of fascin, extracellular matrix metalloproteinase inducer, and ezrin expressions in colorectal adenocarcinoma
Jung Eun-Joo,Lee Ju-Han,Min Byung-Wook,Kim Young-Sik
Indian Journal of Pathology and Microbiology , 2011,
Abstract: Background: The over expression of fascin, extracellular matrix metalloproteinase inducer (EMMPRIN), and ezrin proteins has been associated with poor prognosis in various carcinomas and sarcomas. However, very few studies have reported the relationship between the expression of fascin, EMMPRIN, and ezrin proteins and the clinico-pathologic parameters of colorectal carcinomas. Aims: The aim was to investigate the relationship between fascin, EMMPRIN, and ezrin proteins in colorectal adenocarcinomas and their correlation with clinico-pathologic parameters. Settings and Design: The expression of fascin, EMMPRIN, and ezrin proteins was studied in 210 colorectal adenocarcinoma patients through immunohistochemical staining. Materials and Methods: Immunohistochemical staining by the avidin-biotin peroxidase method was done. The scoring of each protein expression was done and divided into three groups (negative, low-, and high-expression groups). Statistical Analysis: A chi-square test, and Kendall′s tau-b correlation test were used for comparing. Survival analysis was performed using the Kaplan-Meier method with log-rank tests and the Cox proportional hazard model. Results: The percentages of the high-expression group of fascin, EMMPRIN, and ezrin proteins in colorectal adenocarcinomas were 24%, 73%, and 62%, respectively. Weak positive correlations were observed among these protein expressions. An increased expression of the fascin protein was significantly associated with advanced tumor depth and shorter survival times, and a high expression of fascin protein was an independent prognostic factor in univariate and multivariate survival analyses. EMMPRIN and ezrin protein expressions were not associated with the clinico-pathologic parameters. Conclusions: The high expression of fascin protein may be an unfavorable prognostic marker for individual colorectal cancer patients.
Life Expectancy Estimate With Bivariate Weibull Distribution Using Archimedean Copula
Eun-Joo Lee, Chang-Hyun Kim & Seung-Hwan Lee
International Journal of Biometric and Bioinformatics , 2011,
Abstract: Archimedean copulas are used to construct bivariate Weibull distributions. Co-movementstructures of variables are analyzed through the copulas, where the tail dependence between thevariables is explored with more flexibility. Based on the distance between the copula distributionand its empirical version, a copula that may best fit data is selected. With extra computing costs,the adequacy of the copula chosen is then assessed. When multiple myeloma data areconsidered, it is found that relationship between survival time of a patient and the hemoglobinlevel is well described by the Clayton copula. The bivariate Weibull distribution constructed by thecopula is used to estimate value at risk from which we investigate the anticipated longest lifeexpectancy of a patient with the disease over the treatment period.
Ascorbic Acid Attenuates Acute Ethanol-Induced Liver Injury in SMP30 Knockout Mice  [PDF]
Eun-Mi Cho, H. M. Arif Ullah, Ahmed K. Elfadl, Myung-Jin Chung, Soong-Koo Kim, Yong Deuk Kim, Eun-Joo Lee, Kyu-Shik Jeong
Food and Nutrition Sciences (FNS) , 2017, DOI: 10.4236/fns.2017.812083
Abstract:
Ascorbic acid (AA) is recognized as a free radical scavenger that protects cells from oxidative stress-induced damage. However, no studies have investigated the role of AA in acute alcoholic liver disease using senescence marker protein-30 (SMP30) knockout (KO) mice. SMP30 is a novel 34-kDa protein involved in AA biosynthesis. The present study aimed to elucidate the physiological functions of AA in acute ethanol-induced liver injury using SMP30 KO mice, which cannot synthesize AA in vivo. After a 4-week experimental period, mice were divided into six groups. The following three groups comprised the ethanol treatment groups: WT-E group (wild-type), KV-E group (AA-supplemented), and KT-E group (AA-deficient). Mice were exposed to an acute dose of ethanol (6 g ethanol/kg) administered by gavage once a day for three days. The other three control groups, namely, WT-C, KV-C, and KT-C control groups, received an equal volume of water via oral administration. Analysis of changes in body weight showed that mice in the KT-E group had significant loss of body weight compared to the control, KV-E, and WT-E groups. Behavioral analysis revealed that alcohol exposure significantly increased alcohol sensitivity in the KT-E group, whereas the WT-E, KV-E, and control groups developed ethanol tolerance. Aspartate transaminase (AST) levels in the KT-E group were significantly higher than those in the control, KV-E, and WT-E groups. The number of large and binucleated hepatocytes was significantly higher in the KT-E group than in the KV-E and WT-E groups. In addition, cytochrome P450 2E1 (CYP2E1) was over expressed in the central vein in the KT-E group when compared to the KV-E and WT-E groups. Our current findings indicate that AA supplementation in SMP30 KO mice can alleviate alcohol-induced liver damage by down regulating CYP2E1 expression. These results suggest that reduced CYP2E1 expression is a novel mechanism responsible for AA-induced reduction of ethanol-mediated oxidative stress.
The 5'-end transitional CpGs between the CpG islands and retroelements are hypomethylated in association with loss of heterozygosity in gastric cancers
Young-Ho Kim, Seung-Jin Hong, Yu-Chae Jung, Sung-Ja Kim, Eun-Joo Seo, Sang-Wook Choi, Mun-Gan Rhyu
BMC Cancer , 2006, DOI: 10.1186/1471-2407-6-180
Abstract: The 5'-transitional area of all human genes (22,297) was measured according to the nearest retroelements to the transcription start sites. For 50 gastric cancer specimens, the level of LOH events on eight cancer-associated chromosomes was estimated using the microsatellite markers, and the 5'-transitional CpGs of 20 selected genes were examined by methylation analysis using the bisulfite-modified DNA.The extent of the transitional area was significantly shorter with the nearest Alu elements than with the nearest L1 and LTR elements, as well as in the extragenic regions containing a higher density of retroelements than in the intragenic regions. The CpG islands neighbouring a high density of Alu elements were consistently hypomethylated in both normal and tumor tissues. The 5'-transitional methylated CpG sites bordered by a low density of Alu elements or the L1 and LTR elements were hypomethylated more frequently in the high-level LOH cases than in the low-level LOH cases.The 5'-transitional methylated CpG sites not completely protected by the Alu elements were hypomethylated in association with LOH events in gastric cancers. This suggests that an irreversible unbalanced decrease in the genomic dose reduces the spread of L1 methylation in the 5'-end regions of genes.Unilateral chromosomal losses detected by a loss of heterozygosity (LOH) analysis are the most common genetic events in solid tumors [1]. The level of chromosomal losses, rather than a single loss, has been consistently shown to be a significant predictor of survival in stage II and III gastrointestinal cancer patients [2-6]. Although chromosomal losses are a part of gene inactivation, in a na?ve sense, the LOH events represent a reduction in the dose of genetic elements. A dosage compensation mechanism, which maintains the dose of the human genome, equalizes the difference in the dose of the X chromosome between males (XY) and females (XX) via pan-chromosomal epigenetic inactivation [7-9]. Therefore, it
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