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Search Results: 1 - 10 of 29832 matches for " Ernani Luis Rhoden "
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A 35-Year-Old Man Presenting Sleep-Related Painful Erections (Erpes): A Case Report and Review of Literature  [PDF]
Daniel de Freitas G. Soares, Ernani Luis Rhoden
Advances in Sexual Medicine (ASM) , 2014, DOI: 10.4236/asm.2014.41002
Abstract: Introduction: Erectile episodes occurring in the night time are considered normal and are usually related to the REM sleep. Spontaneous painful erections are unusual but they can have a great impact in the patient’s quality of sleep and, for consequence, quality of life. Report: We present a patient who has been presenting painful erections which wake him up almost every night. We discuss the workup and treatment offered to the patient, as well as the short-time response and two months follow-up. Discussion: Although studies still do not explain this relationship, nocturnal erections occur only during rapid eye movement (REM) sleep, which can be confirmed by polysomnography accompanied by Nocturnal Penile Tumescence testing or RigiScan test. However, diagnosis can be established based exclusively on clinical aspects. Based on all literature reviewed, the initial treatment should safely consist in improvement in sleep architecture and pelvis muscles relaxation. Conclusion: After the first suspicion, polysomnography with rigidity measurements of nocturnal erections should be considered although clinical diagnosis and therapeutic test may be acceptable. The management we suggest is usually effective, well tolerated and sustained.
Cancer de próstata e testosterona: riscos e controvérsias
Rhoden, Ernani Luis;Averbeck, Márcio Augusto;
Arquivos Brasileiros de Endocrinologia & Metabologia , 2009, DOI: 10.1590/S0004-27302009000800008
Abstract: hypogonadism is a clinical and biochemical syndrome which may cause significant detriment in the quality of life. with the increase in life expectancy and prostate cancer survival a significant increase in the number of men with hypogonadism who have undergone presumably curative treatment for pca is anticipated. despite the widespread contraindication of testosterone in men with known or suspected prostate cancer, there is no convincing evidence that the normalization of testosterone serum levels in men with low, but not castrate levels, is deleterious. although further studies are necessary before definitive conclusions can be drawn, the available evidence suggests that testosterone replacement therapy can be cautiously considered in selected hypogonadal men treated with curative intent for low risk prostate cancer and without evidence of active disease.
Serum levels of hypothalamic-pituitary-testicular axis hormones in men with or without prostate cancer or atypical small acinar proliferation
Schmitt, Caio da Silva;Rhoden, Ernani Luis;Almeida, Gilberto Laurino;
Clinics , 2011, DOI: 10.1590/S1807-59322011000200001
Abstract: introduction: substantial controversy exists regarding the association between testosterone serum levels and prostate cancer. objective: to evaluate the levels of hypothalamic-pituitary-testicular axis hormones in the sera of men with prostate cancer and atypical small acinar proliferation as well as those with normal biopsies. methods: a study cohort of 186 men with suspected prostate cancer who had undergone transrectal prostate biopsies was used in this study. the patients were divided into the following three groups based on the histology of the biopsy samples: no neoplasia, atypical small acinar proliferation or prostate cancer. demographic data were also collected. levels of total testosterone, follicle-stimulating hormone, luteinizing hormone, prolactin, estradiol, and serum prostate-specific antigen were measured in blood samples. results: initially, 123 men were found to be without neoplasia, 26 with atypical small acinar proliferation and 37 with prostate cancer. after a second biopsy was taken from the men diagnosed with atypical small acinar proliferation, the diagnoses were revised: 18 were diagnosed with atypical small acinar proliferation and 45 with prostate cancer. no significant differences between the groups were identified regarding age, smoking history, chronic diseases, body mass index or psa levels (p >.0.05). the mean serum levels of testosterone, follicle-stimulating hormone, luteinizing hormone, prolactin and estradiol were similar in all of the groups (p >.0.05). furthermore, in individuals with prostate cancer, the gleason scores and prevalence of hypogonadism were not significantly different (p.> 0.05). conclusion: the present study revealed no difference in the serum levels of testosterone, follicle-stimulating hormone, luteinizing hormone, prolactin or estradiol in men without neoplasia compared with those with atypical small acinar proliferation or prostate cancer.
Acompanhamento de um modelo de indu??o de cirrose em ratos mediante vídeolaparoscopia
Farias, Enelruy ávila;Fontes, Paulo Roberto Ott;Rhoden, Cláudia Ramos;Lucas, Márcio Luís;Leal, Márcio Luís Migliavacca;Sabedotti, Marcelo;Rhoden, Ernani Luis;
Acta Cirurgica Brasileira , 2000, DOI: 10.1590/S0102-86502000000300005
Abstract: the authors present a model of experimental vídeolaparoscopy to evaluate the hepatotoxicity induced by carbon tetrachloride (ccl4) in rats. nodules in hepatic surface and significative increase of hepatobiliar function tests (alanine aminotransferase, aspartate aminotransferase, alkaline phosphastase, and gammaglutamyltranspeptidase) were observed in rats treated with ccl4. furthermore, liver cirrhosis was diagnosed by histopathologic study in all rats submitted to administration of ccl4. in this manner, experimental vídeolaparoscopy in rats seems be a excelent diagnostic method that merits further investigation to explore the physiologic consequences of laparoscopic surgery.
Urethral catheter removal 7 or 14 days after radical retropubic prostatectomy: clinical implications and complications in a randomized study
Souto, Carlos Ary Vargas;Rhoden, Ernani Luis;De Conti, Rafael;Chammas Jr., Mário;Laste, Sandro Eduardo;Fornari, Alexandre;Ribeiro, Eduardo Porto;Scholl, Liana;Teloken, Claudio;Souto, José Carlos Stumpf;
Revista do Hospital das Clínicas , 2004, DOI: 10.1590/S0041-87812004000500007
Abstract: purpose: to evaluate the hypothesis that a 7-day period of indwelling catheter after radical retropubic prostatectomy is effective and safe without the need of performing cystography. methods: in the period from january of 2000 to july of 2002, 73 patients underwent radical retropubic prostatectomy, and these patients were prospectively randomized in 2 groups: group 1-37 patients who had the urethral catheter removed 7 days after the procedure, and group 2-36 patients who had the catheter removed 14 days after the surgery. the 2 groups were similar, the surgeons and the technique were the same, and no cystography was performed to evaluate the presence of leaks. results: two patients in group 1 had bleeding and clot retention after having the catheter taken out in the seventh postoperative day and were managed by putting the catheter back in for 7 more days. two patients in group 2 developed bladder neck stricture and were treated by bladder neck incision with success. the continence rate was the same, with 2 cases of incontinence in each group. about 2 pads a day were used by the patients with incontinence. the average follow-up was 17.5 months (12-36 months). no urinary fistula, urinoma, or pelvic abscesses developed after catheter removal. two patients were excluded from the analysis of this series: 1 died with a pulmonary embolus in the third postoperative day, and 1 developed a urinary suprapubic fistula before catheter withdrawal, which was maintained for 16 days. conclusion: withdrawal of the urethral catheter 7 days after radical retropubic prostatectomy, without performing cystography, has a low rate of short-term complications that are equivalent to withdrawal 14 days after the surgery.
Efeitos do alopurinol sobre a lipoperoxida o de membranas celulares renais na síndrome da isquemia e reperfus o: estudo experimental em ratos
Rhoden Ernani Luís,Mauri Marcelo,Petteffi Leonardo,Dacanal Francisco
Acta Cirurgica Brasileira , 1998,
Abstract: Objetivo: Vários estudos têm demonstrado que Radicais Livres de Oxigênio (RLO) contribuem para o dano celular decorrente da isquemia e reperfus o. Este estudo foi desenvolvido como o objetivo de avaliar os efeitos da isquemia e reperfus o renal em ratos, tratados ou n o com alopurinol, sobre a lipoperoxida o (LPO) das membranas celulares renais. Método: Foram usados ratos Wistar distribuídos em 4 grupos e submetidos a períodos de isquemia e reperfus o renal ou n o, dependendo do grupo. Também foram submetidos ou n o a tratamento com alopurinol na dose de 50 e 150 mg/Kg por via intraperitoneal, 5 e 1 horas antes do procedimento. Na avalia o da lipoperoxida o utilizou-se os métodos do TBARS e QL. Resultados: Os resultados demonstraram aumento da LPO nos animais submetidos a isquemia e reperfus o renal. No entanto, estes efeitos deletérios foram reduzidos com o pré-tratamento com alopurinol (p<0,05). Conclus o: O dano causado em animais submetidos a isquemia e reperfus o renal pode ser demonstrado e quantificado pela LPO. Além disso, o alopurinol demonstrou prote o renal contra o dano decorrente desta síndrome, diminuindo a LPO nestes animais. Estes resultados sugerem que a via da xantina oxidase é uma das mais importantes rotas metabólicas envolvidas na gera o de RLO, estes responsáveis em parte pelos danos funcionais do rim na síndrome da isquemia e reperfus o deste órg o.
Taxa de mortalidade em ratos submetidos à isquemia e reperfus o hepática, tratados ou n o com alopurinol
Rhoden Ernani Luís,Mauri Marcelo,Rhoden Cláudia Ramos,Leal Márcio Luís Migliavacca
Acta Cirurgica Brasileira , 1999,
Abstract: A isquemia transitória hepática tem sido cada vez mais amplamente utilizada. Contudo, essa atitude, embora muitas vezes benéfica, é contrabalan ada pelos efeitos adversos advindos da isquemia hepática e da congest o esplênica, assim como, das conseqüências da reperfus o. O objetivo dos autores é determinar os efeitos da isquemia seletiva em animais pré-tratados ou n o com alopurinol, inibidor da xantina oxidase sobre a mortalidade dos animais. Foram utilizados 30 ratos assim divididos: Grupo I (n=10): pré-tratados com alopurinol e submetidos à laparotomia e exposi o do pedículo hepático por 45 minutos. Grupo II (n=10): tratados com alopurinol e submetidos à isquemia hepática seletiva por 45 minutos. Grupo III (n=10): submetidos apenas à isquemia por 45 minutos. A mortalidade pós-operatória foi avaliada a cada 24 horas, por um período de 10 dias. Entre os animais do grupo I, n o foram observados óbitos, entretanto, naqueles dos grupos II e III, as mortalidades globais foram respectivamente 20 e 46,7%. Diferen a estatisticamente significativa, apenas, entre a mortalidade observada no grupo III em rela o ao controle (p<0,05). A mortalidade pós-operatória no grupo de animais submetidos à isquemia sem pré-tratamento com alopurinol ascende as cifras de 46,67% dos animais, enquanto naqueles pré-tratados com alopurinol houve um importante decréscimo para 20%. Embora sem uma distin o estatisticamente significativa, reflete uma tendência de um efeito protetor do alopurinol na isquemia e reperfus o hepática.
Value of prostate specific antigen in predicting the existence of bone metastasis in scintigraphy
Rhoden, Ernani L.;Torres, Olavo;Ramos, Gabriel Z.;Lemos, Rafael R.;Souto, Carlos A.V.;
International braz j urol , 2003, DOI: 10.1590/S1677-55382003000200005
Abstract: objective: evaluate the ability of serum concentration of prostate specific antigen (psa) between 2 cutting points to predict the existence of bone metastasis confirmed by bone scintigraphy in man with prostate cancer. materials and methods: two hundred and fourteen consecutive patients with prostate cancer were evaluated during the present study in the period from 1998 to 2001. from all patients, psa serum concentrations and bone scintigraphy were obtained. for the study, 2 cutting points of psa (10 and 20 ng/ml) were adopted to predict the existence of bone metastasis. results: from the 214 patients, 35 (16.3%) presented positive scintigraphic examinations for the presence of bone metastasis. no patient presented bone metastasis in scintigraphy if having psa < 10 ng/ml, and in only 1 patient (0.46%) with bone metastasis psa concentration was < 20 ng/ml. therefore, when the cutting point adopted for psa serum concentration was 10 ng/ml, a negative predictive value for bone metastasis was 100% with sensitivity rates of 100%. nevertheless, the positive predictive value and the specificity of the method were, respectively, 24.5% and 39.7%. when the cutting point of psa serum concentration was 20 ng/ml, an increment was observed in rates of positive predictive value and specificity (41.5% and 73.2%), respectively, without substantial changes in negative predictive value (99.2%) and sensitivity (97.1%) of the method. conclusions: data of present study allow for the conclusion that psa serum concentration over 20 ng/ml was a more accurate cutting point than psa serum concentration over 10 ng/ml to predict the presence of bone metastasis in scintigraphy.
Value of prostate specific antigen in predicting the existence of bone metastasis in scintigraphy
Rhoden Ernani L.,Torres Olavo,Ramos Gabriel Z.,Lemos Rafael R.
International braz j urol , 2003,
Abstract: OBJECTIVE: Evaluate the ability of serum concentration of prostate specific antigen (PSA) between 2 cutting points to predict the existence of bone metastasis confirmed by bone scintigraphy in man with prostate cancer. MATERIALS AND METHODS: Two hundred and fourteen consecutive patients with prostate cancer were evaluated during the present study in the period from 1998 to 2001. From all patients, PSA serum concentrations and bone scintigraphy were obtained. For the study, 2 cutting points of PSA (10 and 20 ng/mL) were adopted to predict the existence of bone metastasis. RESULTS: From the 214 patients, 35 (16.3%) presented positive scintigraphic examinations for the presence of bone metastasis. No patient presented bone metastasis in scintigraphy if having PSA < 10 ng/mL, and in only 1 patient (0.46%) with bone metastasis PSA concentration was < 20 ng/mL. Therefore, when the cutting point adopted for PSA serum concentration was 10 ng/mL, a negative predictive value for bone metastasis was 100% with sensitivity rates of 100%. Nevertheless, the positive predictive value and the specificity of the method were, respectively, 24.5% and 39.7%. When the cutting point of PSA serum concentration was 20 ng/mL, an increment was observed in rates of positive predictive value and specificity (41.5% and 73.2%), respectively, without substantial changes in negative predictive value (99.2%) and sensitivity (97.1%) of the method. CONCLUSIONS: Data of present study allow for the conclusion that PSA serum concentration over 20 ng/mL was a more accurate cutting point than PSA serum concentration over 10 ng/mL to predict the presence of bone metastasis in scintigraphy.
Taxa de mortalidade em ratos submetidos à isquemia e reperfus?o hepática, tratados ou n?o com alopurinol
Rhoden, Ernani Luís;Mauri, Marcelo;Rhoden, Cláudia Ramos;Leal, Márcio Luís Migliavacca;Sabedotti, Marcelo;Lucas, Márcio Luís;Pereira-Lima, Luiz;
Acta Cirurgica Brasileira , 1999, DOI: 10.1590/S0102-86501999000400003
Abstract: the transitory hepatic ischemia has been frequently used. however, this procedure, benefic some times, is contrabalanced by the adverse effects from the hepatic ischemia and esplenic congestion, as well as of the reperfusion consequences. the objective of the authors is to determine the effects of the selective ischemia in pretreated and not pretreated rats with allopurinol, inhibitor of the xantine oxidase enzyme, in the mortality of the rats. thirthy wistar rats were used and divided into three groups: group i (n=10): pretreated with allopurinol and submitted to laparotomy and exposition of the hepatic vessels for 45 min. group ii (n=10): pretreated with allopurinol and submitted to selective hepatic ischemia for 45 minutes. group iii (n=10): submitted only to selective hepatic ischemia for 45 min. the postoperative mortality was evaluated each 24 hours, by one period of 10 days. among the animals of the group 1, it wasn't observed deaths, however, in those of the groups ii and iii, the global rates of mortality were, respectively, 20 and 46.67%. statistically significative difference , was bettwen the observed mortality in groups i and iii (p<0.05). the postoperative mortality in the group of animals submitted to ischemia without pretreatment with allopurinol was 46.67%, while in those animals pretreated with allopurinol, there was an important decrease to 20%. even without an statistically significative distinction, it reflects a tendency of a protector effect of the allopurinol in the hepatic ischemia and reperfusion.
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