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Search Results: 1 - 10 of 74465 matches for " Eny Maria;Maníglia "
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Polimorfismos GSTT1 e GSTM1 em indivíduos tabagistas com carcinoma espinocelular de cabe?a e pesco?o
Biselli, Joice Matos;Leal, Renata Cristina de Angelo Calsaverini;Ruiz, Mariangela Torreglosa;Goloni-Bertollo, Eny Maria;Maníglia, José Victor;Rossit, Andréa Regina Baptista;Pavarino-Bertelli, érika Cristina;
Revista Brasileira de Otorrinolaringologia , 2006, DOI: 10.1590/S0034-72992006000500012
Abstract: gene variability related to carcinogen activation and detoxification may interfere with susceptibility to head and neck cancer. aim: to investigate the relation between gstt1 and gstm1 null polymorphisms and the risk of head and neck squamous cell carcinoma in cigarette smokers. material and method: a case-control study conducted at the sao jose do rio preto medical school, brazil. gstm1 and gstt1 null genotype frequencies were evaluated by multiplex pcr in 45 cigarette smokers with head and neck squamous cell carcinomas and 45 cigarette smokers without this disease. results: the oral cavity was the most prevalent tumor site for squamous cell carcinoma. the gstt1 null genotype was found in 33.3% of the experimental group and 23.3% of the control group (p= 0.311). experimental and control groups had gstm1 null genotype frequencies of 35% and 48.3% (p=0.582). no association between alcohol consumption and gstt1 and gstmi null genotypes was found in these groups (p-values>0.05). there were more men, and alcohol consumption was prevalent in both groups. conclusion: in this study we were unable to show a correlation between gstm1 and gstt1 genotypes and the development of head and neck squamous cell carcinomas in cigarette smokers.
Avalia??o da influência da nulidade dos genótipos GSTT1 e GSTM1 na carcinogênese em cabe?a e pesco?o
Goloni-Bertollo, Eny Maria;Biselli, Joice Matos;Corrêa, Léa Carolina deLima;Maníglia, José Victor;Rossit, Andréa Regina Baptista;Ruiz, Mariangela Torreglosa;Pavarino-Bertelli, érika Cristina;
Revista da Associa??o Médica Brasileira , 2006, DOI: 10.1590/S0104-42302006000500028
Abstract: background: to evaluate the influence of gstm1 and gstt1 null genotypes in head and neck carcinogenesis. methods: the frequencies of gstm1 and gstt1 null genotypes were evaluated by multiplex polymerase chain reaction (pcr) in 45 patients with head and neck squamous cell carcinoma and in 45 control group individuals. both groups were composed of smokers paired by gender, age and race. results: the gstt1 null genotype was found in 24.4% of the patients and 17.7% of the control group (p= 0.606), while 44.4% of the patients and 48.8% of the control group were bearers of the gstm1 null genotype (p=0.832). no associations between gstt1 and gstmi null genotypes and primary tumor sites were found. conclusion: in our study, it was impossible to establish the influence of the gstt1 and gstm1 null genotypes in head and neck carcinogenesis.
Altera??o da temperatura radicular externa durante o preparo para conten??o intra-radicular
FERREIRA, Cláudio Maníglia;ORSI, Iara Augusta;FR?NER, Izabel Cristina;
Revista de Odontologia da Universidade de S?o Paulo , 1999, DOI: 10.1590/S0103-06631999000300013
Abstract: the objective of the present study was to compare the change in temperature on the external surface of the root in vitro during post and core preparation using 4 different techniques. forty lower single-root premolars instrumented and filled with gutta-percha and stored in 10% formalin were divided into 4 groups according to the technique of gutta-percha removal employed, using heated endodontic pluggers and peeso, largo and gates-glidden burs. the experiment was performed in a chamber with controlled temperature maintained at about 26°c. for gutta-percha removal from the canals, 2/3 of the root length was calculated and approximately 4 mm of apical filling was left. the temperature of the external surface of the root was measured with a thermo-couple connected to a multimeter and measurements were made in 3 regions: cervical (about 3 mm below the cementum-enamel junction), middle and apical regions of a predetermined measurent. analysis of variance indicated significant differences (p < 0.01) between regions and techniques. the complementary tukey test indicated that the heated endodontic pluggers produced the greatest increased in temperature among the three techniques, and the peeso bur produced the greatest increase in temperature among the burs used. among regions, the apical one presented the greatest change in temperature for all the techniques evaluated.
Altera o da temperatura radicular externa durante o preparo para conten o intra-radicular
FERREIRA Cláudio Maníglia,ORSI Iara Augusta,FR?NER Izabel Cristina
Revista de Odontologia da Universidade de S?o Paulo , 1999,
Abstract: O objetivo deste trabalho foi comparar in vitro a altera o de temperatura na superfície radicular externa durante o preparo para conten o intra-radicular utilizando 4 técnicas de remo o da guta-percha: condensadores aquecidos, brocas de Peeso, Gates-Glidden e Largo, em 40 dentes pré-molares inferiores (unirradiculares) tratados endodonticamente. O experimento foi realizado em uma camara com temperatura controlada em torno de 26°C. Para a remo o da guta-percha do interior dos canais, foram calculados dois ter os do comprimento da raiz, deixando em torno de 4 mm de obtura o apical. As medi es da temperatura radicular externa foram realizadas com um termopar acoplado a um multímetro e efetuadas em 3 regi es: cervical (em torno de 3 mm abaixo da jun o cemento-esmalte), média e apical. A análise de variancia indicou diferen as significantes (p < 0,01) entre as regi es e as técnicas utilizadas. O teste complementar de Tukey indicou que os condensadores aquecidos produziram o maior aumento de temperatura dentre as técnicas, e a broca de Peeso dentre as brocas, seguida pela de Largo e de Gates-Glidden. Dentre as regi es, a apical apresentou a maior altera o de temperatura em todas as técnicas avaliadas.
Estudo da degrada??o do herbicida ácido 2,4- diclorofenoxiacético (2,4-D) por meio da radia??o gama do cobalto-60 em solu??o aquosa contendo ácido húmico
Campos, Sandro Xavier de;Vieira, Eny Maria;
Química Nova , 2002, DOI: 10.1590/S0100-40422002000400003
Abstract: the use of pesticides in agriculture presents some problems to ecosytems as a consequence of their remaining in the environment. conventional methods for environmental decontamination sometimes just transfer these residues from one place to another. the use of gamma radiation from cobalt-60 to induce 2,4-d degradation in aqueous solution containing humic acid was studied. results show that the herbicide is completely degraded after treatment with a 30 kgy dose. there were decreases in the degradation of the 2,4-d when humic acid was added at all doses. some radiolytic products are proposed. the 2,4-d radiolytic yields (g) from 2,4-d were calculated.
Adsor??o/dessor??o do explosivo tetril em turfa e em argissolo vermelho amarelo
Falone, Sandra Zago;Vieira, Eny Maria;
Química Nova , 2004, DOI: 10.1590/S0100-40422004000600002
Abstract: this paper presents the study of adsorption/desorption of the explosive tetryl (2,4,6-trinitrophenylmethyl-nitramine) in different matrices, such as in natura soil, roasted soil, humic acid of soil, in natura peat, roasted peat and humic acid of peat. the aim of the study is to evaluate the interaction capacity of those matrices with the explosive. the analytic technique used was hplc (high performance liquid chromatography), with uv-detection at 230 nm. the freundlich isotherms were utilized for the mathematical treatment of the data. the results indicated that in natura soil and in natura peat (with organic substances) are excellent matrices for the retention of tetryl, adsorbing it and keeping it immovable, preventing it from contaminating the groundwater. the largest adsorption of the explosive ocurred in in natura soil, while the smallest desorption was observed in in natura peat. after the calcination of the matrices, the smallest adsorption was observed, indicating that the retention occurs in the organic substance.
Estudo da degrada o do herbicida ácido 2,4- diclorofenoxiacético (2,4-D) por meio da radia o gama do cobalto-60 em solu o aquosa contendo ácido húmico
Campos Sandro Xavier de,Vieira Eny Maria
Química Nova , 2002,
Abstract: The use of pesticides in agriculture presents some problems to ecosytems as a consequence of their remaining in the environment. Conventional methods for environmental decontamination sometimes just transfer these residues from one place to another. The use of gamma radiation from cobalt-60 to induce 2,4-D degradation in aqueous solution containing humic acid was studied. Results show that the herbicide is completely degraded after treatment with a 30 kGy dose. There were decreases in the degradation of the 2,4-D when humic acid was added at all doses. Some radiolytic products are proposed. The 2,4-D radiolytic yields (G) from 2,4-D were calculated.
Adsor o/dessor o do explosivo tetril em turfa e em argissolo vermelho amarelo
Falone Sandra Zago,Vieira Eny Maria
Química Nova , 2004,
Abstract: This paper presents the study of adsorption/desorption of the explosive tetryl (2,4,6-trinitrophenylmethyl-nitramine) in different matrices, such as in natura soil, roasted soil, humic acid of soil, in natura peat, roasted peat and humic acid of peat. The aim of the study is to evaluate the interaction capacity of those matrices with the explosive. The analytic technique used was HPLC (high performance liquid chromatography), with UV-detection at 230 nm. The Freundlich isotherms were utilized for the mathematical treatment of the data. The results indicated that in natura soil and in natura peat (with organic substances) are excellent matrices for the retention of tetryl, adsorbing it and keeping it immovable, preventing it from contaminating the groundwater. The largest adsorption of the explosive ocurred in in natura soil, while the smallest desorption was observed in in natura peat. After the calcination of the matrices, the smallest adsorption was observed, indicating that the retention occurs in the organic substance.
Evaluation of the dentin remaining after flaring using Gates Glidden drills and Protaper rotary files
Bruno Carvalho Sousa,José Ribamar Costa Filho,Fábio de Almeida Gomes,Cláudio Maníglia-Ferreira
RSBO , 2011,
Abstract: Introduction: The application of rotary instruments for root canal preparation requires a safe, not harming procedure to the root structure remaining. Objective: The purpose of this study was to analyze the root thickness in 28 mesial canals of lower permanent first molars before and after flaring using two rotary instruments: Gates-Glidden drills and ProTaper rotary files. Material and methods: Teeth were embedded into a muffle system. Samples were obtained by cutting 2mm below the furcation. The images were captured by a digital video system (8X and 12X magnification). For image 0.858 mm and 0.486 mm for ProTaper, respectively. No statistical differences were found in the root thickness of specimens shaped with ProTaper rotary files and Gates Glidden drills. Conclusion: The use of Gates-Glidden drills is as safe as ProTaper rotary files with respect to danger of perforation on the distal side of the mesial roots of lower molars.analysis and processing, Pro-Image Plus 4.1 software was used. Each image captured by the computer was gauged, eliminating any possible distortion. Gates-Glidden drills were used in decreasing order of size (GG#4, GG#3, GG#2). ProTaper was used according to the manufacturer’s recommendations, with hand-piece powered by an electric motor with low torque. 5.25% sodium hypochlorite was utilized as irrigant. Results: The average thickness between the canal and furcation before and after use of rotary instruments were: 0.857 mm and 0.561 mm for Gates-Glidden drills, and
Cancer de cabe a e pesco o: causas, preven o e tratamento Head and neck cancer: causes, prevention and treatment
Ana Lívia Silva Galbiatti,Jo?o Armando Padovani-Junior,José Victor Maníglia,Cléa Dometilde Soares Rodrigues
Brazilian Journal of Otorhinolaryngology , 2013,
Abstract: Cancer de cabe a e pesco o é o quinto tipo de cancer mais comum e a taxa de sobrevivência n o tem mudado nos últimos anos. OBJETIVO: Determinar os fatores de risco, causas, tratamento e preven o do cancer de cabe a e pesco o. MéTODO: Nós detalhamos os fatores de risco, causas, tratamento e preven o da doen a por meio de pesquisa nos bancos de dados PUBMED, MEDLINE e SciELO. RESULTADOS: álcool e fumo ainda s o os principais fatores de risco. Outros fatores podem influenciar o desenvolvimento do carcinoma de cabe a e pesco o. A op o de tratamento principal é terapia cirúrgica e sua utiliza o seguida por radioterapia é uma prática comum de tratamento em fases iniciais da doen a. Existem terapias que visam agir em componentes moleculares genéticos específicos para o desenvolvimento do tumor. A cessa o do cigarro, limita o de ingest o de álcool, evitar a exposi o à fuma a do cigarro, a carcinogênicos ambientais, detec o precoce de infec o por HPV, manuten o da saúde bucal, bons hábitos alimentares e controle do stress podem ser medidas de preven o da doen a. CONCLUS O: Investiga es adicionais s o necessárias para completa compreens o do desenvolvimento do carcinoma de cabe a e pesco o e isso irá fornecer novos caminhos e melhora na interven o e abordagens terapêuticas. Although head and neck carcinoma ranks fifth among cancer types, patient survival rates have not changed significantly over the past years. OBJECTIVE: To determine the risk factors, causes, therapies, and prevention measures for head and neck cancer. METHOD: Risk factors, causes, therapies, and preventive measures for this disease were searched on databases PUBMED, MEDLINE, and SCIELO. RESULTS: Alcohol and tobacco are still atop risk factors. Other factors may influence the development of head and neck carcinoma. Surgery is the main treatment option, and the addition of radiotherapy following surgery is frequent for patients in the early stages of the disease. Other therapies target specific genetic molecular components connected to tumor development. Disease preventive measures include smoking cessation, limiting alcohol intake, preventing exposure to tobacco smoke and environmental carcinogenic agents, early detection of infection by HPV, maintaining oral health, good eating habits, and managing stress. CONCLUSION: Additional research is needed for a more thorough understanding of the development of head and neck carcinomas and to shed light on new ways to improve therapeutic approaches and interventions.
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