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Search Results: 1 - 10 of 3467 matches for " Elisa Brietzke "
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The "selfish brain" hypothesis for metabolic abnormalities in bipolar disorder and schizophrenia
Mansur, Rodrigo Barbachan;Brietzke, Elisa;
Trends in Psychiatry and Psychotherapy , 2012, DOI: 10.1590/S2237-60892012000300003
Abstract: metabolic abnormalities are frequent in patients with schizophrenia and bipolar disorder (bd), leading to a high prevalence of diabetes and metabolic syndrome in this population. moreover, mortality rates among patients are higher than in the general population, especially due to cardiovascular diseases. several neurobiological systems involved in energy metabolism have been shown to be altered in both illnesses; however, the cause of metabolic abnormalities and how they relate to schizophrenia and bd pathophysiology are still largely unknown. the "selfish brain" theory is a recent paradigm postulating that, in order to maintain its own energy supply stable, the brain modulates energy metabolism in the periphery by regulation of both allocation and intake of nutrients. we hypothesize that the metabolic alterations observed in these disorders are a result of an inefficient regulation of the brain energy supply and its compensatory mechanisms. the selfish brain theory can also expand our understanding of stress adaptation and neuroprogression in schizophrenia and bd, and, overall, can have important clinical implications for both illnesses.
Coping como fun o executiva
GrassiOliveira, Rodrigo,Daruy Filho, Ledo,Brietzke, Elisa
Psico , 2008,
Abstract: As respostas de adapta o (coping) referem-se às estratégias para adaptar o indivíduo ao estresse. Este artigo teórico revisa a estrutura do coping em quatro níveis, com o nível inferior correspondendo às "instancias" de coping e o nível superior correspondendo às "estratégias de adapta o". Assim é introduzida frontais. Prop e-se que o coping ocorreria através de um controle primário, ou a o direta na fonte de estresse/emo es, de um controle secundário ou adapta o à fonte de estresse, e do desligamento ou escape da fonte de estresse/emo es desagradáveis. Também se argumenta que o coping envolveria a avalia o, planejamento, análise e antecipa o dos resultados, processos tipicamente vinculados às fun es executivas.
New perspectives on coping in bipolar disorder
Grassi-Oliveira, Rodrigo;Daruy-Filho, Ledo;Brietzke, Elisa;
Psychology & Neuroscience , 2010, DOI: 10.3922/j.psns.2010.2.005
Abstract: bipolar disorder (bd) is a prevalent and highly disabling psychiatric condition. despite the widely acknowledged importance of psychosocial interventions that involve a complex cognitive, behavioral, and biological process to help patients cope better with their illness, few studies have systematically evaluated coping in bd. therefore, our objective was to examine recent developments in current research on coping in bd. several studies have documented a strong association between bd and numerous neuroanatomical and neuropsychological abnormalities, particularly multiple episodes and longer durations of the disorder. the most marked effects of bd encompass brain areas involved in executive function, which may affect the mechanisms underlying an adequate selection of coping strategies. thus, the ability of individuals to reduce their own stress burden is impaired, increasing vulnerability to stressful life events and negatively affecting the course of bd. psychosocial interventions that focus on bd should be evaluated for their ability to improve coping abilities, and research on bd should consider neuropsychological impairment and cognitive-behavioral strategies for coping with stress.
Early intervention for bipolar disorder: current imperatives, future directions
Taylor, Matthew;Bressan, Rodrigo Affonseca;Pan, Pedro Mario;Brietzke, Elisa;
Revista Brasileira de Psiquiatria , 2011, DOI: 10.1590/S1516-44462011000600006
Abstract: objectives: the objective of this article is to discuss the rationale/background for early intervention in bipolar disorder. method: narrative review. results: there are often significant delays before the diagnosis of bipolar disorder is made and effective management initiated. growing evidence from both preclinical and clinical literature points to a clear need for improved early identification and early intervention in bipolar disorder. increasing efforts are being applied to the identification of those at high risk of onset of bipolar disorder. it is hoped that identification of an early prodrome of illness will allow preventative measures to be taken. conclusions: there is a clear rationale for improved early identification and early intervention in bipolar disorder.
"Life Chart" retrospectivo: instrumento para assinalar graficamente a presen?a e a evolu??o do impacto funcional de episódios afetivos maníacos e depressivos
Brietzke, Elisa;Daruy Filho, Ledo;Grassi-Oliveira, Rodrigo;
Revista de Psiquiatria Clínica , 2009, DOI: 10.1590/S0101-60832009000600001
Abstract: background: a life chart is a widely used instrument both in research and clinical practice to document the longitudinal course of bipolar disorder, being easy to apply and accuratly reports the clinical history. objective: the goal of this paper is to present the brazilian portuguese version of the retrospective life chart. methods: translation and retrotranslation, review, and semantic, language, cultural and conceptual equivalence were done. results: results are presented in graphic format. discussion: the portuguese version of life chart will allow that studies conducted in brazil to use the same parameters that are used in international research.
Comorbidades médicas em pacientes ambulatoriais com transtorno do humor bipolar tipo I
Moreira, Camila Luzia Roganti Leite;Brietzke, Elisa;Lafer, Beny;
Revista de Psiquiatria Clínica , 2011, DOI: 10.1590/S0101-60832011000600003
Abstract: background: bipolar disorder (bd) has been associated with high rates of general medical comorbidities (gmc) and medical risk factors. there have been scarce reports about this prevalence in brazilian subjects with bd. objective: describe the prevalence of gmc in a sample of bd type i patients. methods: clinical records of 195 patients with bd type i were reviewed for identification of gmc. patients with and without gmc were compared using the mann-whitney nonparametric test and the chi-square test. results: sixty-three percent of patients had at least one medical comorbidity. the most prevalent conditions were: migraine (31.8%), hypothyroidism (24.1%), hypertension (11.3%), traumatic brain injuries (10.3%), asthma (9.7%), epilepsy (8.2%), diabetes (5.1%), stroke (2.1%) and hyperthyroidism (1%). age and duration of illness were positively associated with the presence of gmc (p < 0.001). discussion: in our study, in accordance with previous reports, the majority of patients presented at least one general medical disorder. the principal limitation of this study is the fact that diagnose of gmc was made based on self-report. there are scarce studies addressing gmc in the brazilian population with bd and this report can contribute to improve diagnostic vigilance, assessment, treatment planning and decrease the burden associated with bd.
Translation and adaptation of Theory of Mind tasks into Brazilian portuguese
Sanvicente-Vieira, Breno;Brietzke, Elisa;Grassi-Oliveira, Rodrigo;
Trends in Psychiatry and Psychotherapy , 2012, DOI: 10.1590/S2237-60892012000400003
Abstract: background: theory of mind (tom) is a field of social cognition that deals with the individual’s cognitive ability to interpret or infer the mental states of others based on previous knowledge. recently, research has shown that this ability is compromised in patients with some psychopathologies, e.g., schizophrenia and autistic disorder. investigators have also shown that deficits in tom have impacts on social functioning and, consequently, on quality of life. even though tom studies have recently grown in number, some problems still remain (e.g., the difficulty of standardized tools to assess tom in different languages). objectives: to describe the translation and adaptation into brazilian portuguese of two of the most important and widely used tom tasks, namely, the theory of mind stories and the hinting task. method: the process included the following steps: 1) translation; 2) production of a single translated version and review by specialists; 3) back-translation into english; 4) review by an english-speaking specialist; 5) adaptation of marked corrections; and 6) pilot application in a group representative of the target population (people with schizophrenia). results: a final translated version was obtained for each of the tasks. both instruments were well understood by participants and can now be used in the brazilian experimental setting. conclusion: the availability of two major tom tasks in brazilian portuguese facilitates the conduction of research on the topic in brazil. in the future, this could help design clinical interventions aimed at people with social and cognitive difficulties.
Translation and adaptation of Theory of Mind tasks into Brazilian portuguese Tradu o e adapta o de tarefas de Teoria da Mente para o português brasileiro
Breno Sanvicente-Vieira,Elisa Brietzke,Rodrigo Grassi-Oliveira
Trends in Psychiatry and Psychotherapy , 2012,
Abstract: BACKGROUND: Theory of mind (ToM) is a field of social cognition that deals with the individual’s cognitive ability to interpret or infer the mental states of others based on previous knowledge. Recently, research has shown that this ability is compromised in patients with some psychopathologies, e.g., schizophrenia and autistic disorder. Investigators have also shown that deficits in ToM have impacts on social functioning and, consequently, on quality of life. Even though ToM studies have recently grown in number, some problems still remain (e.g., the difficulty of standardized tools to assess ToM in different languages). OBJECTIVES: To describe the translation and adaptation into Brazilian Portuguese of two of the most important and widely used ToM tasks, namely, the Theory of Mind Stories and the Hinting Task. METHOD: The process included the following steps: 1) translation; 2) production of a single translated version and review by specialists; 3) back-translation into English; 4) review by an English-speaking specialist; 5) adaptation of marked corrections; and 6) pilot application in a group representative of the target population (people with schizophrenia). RESULTS: A final translated version was obtained for each of the tasks. Both instruments were well understood by participants and can now be used in the Brazilian experimental setting. CONCLUSION: The availability of two major ToM tasks in Brazilian Portuguese facilitates the conduction of research on the topic in Brazil. In the future, this could help design clinical interventions aimed at people with social and cognitive difficulties. INTRODU O: A teoria da mente (theory of mind, ToM) é um domínio da cogni o social que se refere à habilidade cognitiva de interpretar ou inferir estados mentais de outras pessoas através de conhecimentos prévios. Recentemente, pesquisas têm mostrado que essa capacidade está comprometida em algumas psicopatologias, como esquizofrenia e autismo. Além disso, pesquisadores têm mostrado que déficits na ToM impactam a funcionalidade social e, consequentemente, a qualidade de vida. Apesar do aumento recente de estudos na área, alguns problemas (por exemplo a dificuldade de instrumentos estandardizados para avaliar essa habilidade em diferentes idiomas). OBJETIVOS: Descrever a tradu o e a adapta o para o português brasileiro de duas das mais importantes e amplamente utilizadas tarefas de ToM - o Theory of Mind Stories e o Hinting Task. MéTODO: O processo incluiu as seguintes etapas: 1) tradu o; 2) produ o de uma vers o unificada e avaliada por especialistas; 3) r
New perspectives on coping in bipolar disorder
Rodrigo Grassi-Oliveira,Ledo Daruy-Filho,Elisa Brietzke
Psychology & Neuroscience , 2010,
Abstract: Bipolar disorder (BD) is a prevalent and highly disabling psychiatric condition. Despite the widely acknowledged importance of psychosocial interventions that involve a complex cognitive, behavioral, and biological process to help patients cope better with their illness, few studies have systematically evaluated coping in BD. Therefore, our objective was to examine recent developments in current research on coping in BD. Several studies have documented a strong association between BD and numerous neuroanatomical and neuropsychological abnormalities, particularly multiple episodes and longer durations of the disorder. The most marked effects of BD encompass brain areas involved in executive function, which may affect the mechanisms underlying an adequate selection of coping strategies. Thus, the ability of individuals to reduce their own stress burden is impaired, increasing vulnerability to stressful life events and negatively affecting the course of BD. Psychosocial interventions that focus on BD should be evaluated for their ability to improve coping abilities, and research on BD should consider neuropsychological impairment and cognitive-behavioral strategies for coping with stress.
Social cognition and Theory of Mind: controversies and promises for understanding major psychiatric disorders
Martins-Junior, Flavio Eduardo;Sanvicente-Vieira, Breno;Grassi-Oliveira, Rodrigo;Brietzke, Elisa;
Psychology & Neuroscience , 2011, DOI: 10.3922/j.psns.2011.3.008
Abstract: the term "social cognition" generally refers to the mental operations that underlie social interactions including the perception and interpretation of the intentions, dispositions, and behaviors of others and the generation of a response to these behaviors. social cognition has been considered a valuable and promising field that strives to understand the nature and outcome of major mental disorders. this article discusses the concept of social cognition and its relationship to theory of mind (tom). theory of mind in autistic spectrum disorders has been studied since the 1980s, and cognitive impairments in these disorders may be restricted to tom deficits because other cognitive domains and nonsocial intelligence are preserved. this article addresses the issues of human ontogeny, reviews the main findings from research on schizophrenia and bipolar disorder, and summarizes the tools commonly used in the assessment of these illnesses.
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