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Search Results: 1 - 10 of 602653 matches for " Eliana A. R.; "
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Síntese, caracteriza??o e degrada??o " in vitro" do Poli(L-ácido láctico)
Motta, Adriana C.;Duek, Eliana A. R.;
Polímeros , 2006, DOI: 10.1590/S0104-14282006000100008
Abstract: the study and application of bioreabsorbable polyesters to repair damaged tissues is a promising research area. poly(l-lactic acid), plla, is the most important bioreabsorbable polyester due to it excellent biocompatibility and bioreabsorption. the aim of this work was to synthesize, characterize and evaluate the in vitro degradation process of plla membranes. the polymer was synthesized by ring opening of the cyclic diester of lactic acid, using as catalyst sn(oct)2. plla presented high values of molar mass (mw around 105 g/mol) and its chemical structure was confirmed by rmn 1h, 13c and ir. the thermal properties of plla were studied by dsc, from which a high cristallinity degree was observed, consistent with the literature. the in vitro degradation of plla membranes demonstrated that the crystallinity degree increased with increasing degradation times.
Síntese e caracteriza??o do copolímero poli (L-co-D,L ácido Láctico)
Motta, Adriana C.;Duek, Eliana A. R.;
Polímeros , 2007, DOI: 10.1590/S0104-14282007000200011
Abstract: bioreabsorbable polymers are routinely used as temporary prostheses for fractured bones. among the bioreabsorbable polymers the poly(l-co-d, l lactic acid), pldla, in the 70:30 rate has been studied to obtain plates and screws to recuperate traumas in the cranium and maxilla facial regions. in this monomers rate, an amorphous polymer is obtained, which allows adaptation of devices in the local for the implant during the surgery. a limiting factor to use this polymer is its high cost, due to the importation process. in this work pldla was synthesized by mass polymerization of the cyclical monomers l-lactic acid and d, l lactic acid, using sn(oct)2 as catalyst. a material with high molar mass (105 g/mol) was obtained and characterized by 1h rmn, 13c rmn, gpc, ftir and dsc.
Avan?os no diagnóstico e tratamento da sepse
Carvalho, Paulo R.A.;Trotta, Eliana de A.;
Jornal de Pediatria , 2003, DOI: 10.1590/S0021-75572003000800009
Abstract: objective: to present a critical and updated review about sepsis, focusing especially on diagnosis and treatment. source of data: literature review of medline, including review articles, clinical trials and original research. summary of the findings: the international sepsis definitions conference amplified the list of possible clinical and laboratory signs of sepsis, which may allow for more efficacious suspicion and management. in terms of laboratory evaluation, in addition to the research for infectious agents, many inflammatory response markers, such as inflammatory cytokines and procalcitonin, have been identified. however, they lack sensitivity and specificity for safe diagnosis. in terms of treatment, early intervention to prevent hemodynamic disturbances is still essential for a positive outcome, together with the appropriate use of antimicrobials. the value of treatments to remove toxins and to increase the innate immune response has not yet been established. the use of isolated inflammatory response blockers, at any stage of sepsis, does not decrease mortality. the use of corticosteroid makes a comeback with encouraging results, even in patients without sepsis-related adrenal insufficiency. a large study on activated protein c (drotrecogin-a) reports a 6% decrease in mortality in a selected sample, suggesting the possibility of a better prognosis for sepsis patients. conclusions: in comparison to the advances of the past few years, little has been achieved in terms of decreasing sepsis-related mortality due to the complexity of the pathogen-host relationships. the individual regulation of host reactions did not have the expected effects. the benefits of some known strategies were confirmed. other types of treatment, such as corticosteroids and activated protein c therapies, are emerging as promising alternatives. research indicates that the combination of immune modulator therapies is probably the best choice to improve outcomes in sepsis.
Malpighiaceae: correlations between habit, fruit type and basic chromosome number
Lombello, Ricardo A.;Forni-Martins, Eliana R.;
Acta Botanica Brasilica , 2003, DOI: 10.1590/S0102-33062003000200001
Abstract: the family malpighiaceae presents species with different habits, fruit types and cytological characters. climbers are considered the most derived habit, followed, respectively, by the shrubby and arboreal ones. the present study examines the relationship between basic chromosome numbers and the derivation of climbing habit and fruit types in malpighiaceae. a comparison of all the chromosome number reports for malpighiaceae showed a predominance of chromosome numbers based on x=5 or 10 in the genera of sub-family malpighioideae, mainly represented by climbers with winged fruits, whereas non-climbing species with non-winged fruits, which predominate in sub-family byrsonimoideae, had counts based on x=6, which is considered the less derived basic number for the family. based on such data, confirmed by statistic assays, and on the monophyletic origin of this family, we admit the hypothesis that morphological derivation of habit and fruit is correlated with chromosome basic number variation in the family malpighiaceae.
Blendas de poli (ácido lático-co-ácido glicólico)/ poli (ácido lático): degrada??o in vitro
Rezende, Camila A. de;Duek, Eliana Ap. R.;
Polímeros , 2003, DOI: 10.1590/S0104-14282003000100009
Abstract: plates of the copolymer poly (lactide-co-glycolide) acid have been produced and used as implants that degrade and are absorbed by the organism. implants that can be absorbed are advantageous in comparison with metallic implants. in this work, plates of the blend poly (lactide- co- glycolide) acid/ poly lactic acid (plga/ plla) were made and characterized during their in vitro degradation process. it was found that blends are immiscible and that their thermal stability increases with the proportion of plla in the blend. the crystallinity degree also increases with the proportion of plla in the sample and with degradation time. besides, it was verified that plga is degraded quickly and its presence and amount modifies clearly the morphology of the blends.
DISE?O Y CONSTRUCCIóN DE UN PROTOTIPO DE INTERFAZ CEREBRO-COMPUTADOR PARA FACILITAR LA COMUNICACIóN DE PERSONAS CON DISCAPACIDAD MOTORA
ARBOLEDA,CAROLINA; GARCíA,ELIANA; POSADA,ALEJANDRO; TORRES,RóBINSON;
Revista EIA , 2009,
Abstract: a brain-computer interface (bci) is a communication system that translates a brain signal (e.g. sensorimotor rhythms, evoked potentials) into a control signal and, therefore, constitutes an innovative communication alternative for people with severe motor disability (such as patients with amyotrophic lateral sclerosis). this project proposes the development of a bci prototype based on the recording of p300 cognitive potentials using electroencephalography. the prototype uses a six-channel electroencephalograph to acquire the signals, and through a visual stimulation matrix containing the letters of the alphabet and icons associated to each one gives the user the possibility of writing words or elaborating messages with the icons. to process the signals (filtering and decimation, among other methods), the software bci2000 and matlab 7.0 were used. the latter was used to program three different linear translation algorithms (linear discriminant analysis, least squares analysis and stepwise linear discriminant analysis), in order to translate the recorded evoked potentials into communication signals.
Malpighiaceae: correlations between habit, fruit type and basic chromosome number
Lombello Ricardo A.,Forni-Martins Eliana R.
Acta Botanica Brasilica , 2003,
Abstract: The family Malpighiaceae presents species with different habits, fruit types and cytological characters. Climbers are considered the most derived habit, followed, respectively, by the shrubby and arboreal ones. The present study examines the relationship between basic chromosome numbers and the derivation of climbing habit and fruit types in Malpighiaceae. A comparison of all the chromosome number reports for Malpighiaceae showed a predominance of chromosome numbers based on x=5 or 10 in the genera of sub-family Malpighioideae, mainly represented by climbers with winged fruits, whereas non-climbing species with non-winged fruits, which predominate in sub-family Byrsonimoideae, had counts based on x=6, which is considered the less derived basic number for the family. Based on such data, confirmed by statistic assays, and on the monophyletic origin of this family, we admit the hypothesis that morphological derivation of habit and fruit is correlated with chromosome basic number variation in the family Malpighiaceae.
Blendas de poli (ácido lático-co-ácido glicólico)/ poli (ácido lático): degrada o in vitro
Rezende Camila A. de,Duek Eliana Ap. R.
Polímeros , 2003,
Abstract: Placas de copolímero de poli(ácido lactico-co-glicólico) têm sido produzidas e usadas como implantes que degradam e s o absorvidos pelo organismo. Implantes que podem ser absorvidos apresentam vantagens em rela o aos implantes metálicos. Nesse trabalho, foram obtidas placas a partir de blendas de poli(ácido lactico-co-glicólico)/ poli(ácido lático), (PLGA/PLLA) e caracterizadas durante o processo de degrada o in vitro. Verificou-se que as blendas s o imiscíveis e a estabilidade térmica das mesmas aumenta com a propor o de PLLA. O grau de cristalinidade também aumenta com a propor o de PLLA na amostra e com o tempo de degrada o. Além disso, verificou-se que o PLGA degrada rapidamente e sua presen a e quantidade modifica nitidamente a morfologia das blendas.
DISE O Y CONSTRUCCIóN DE UN PROTOTIPO DE INTERFAZ CEREBRO-COMPUTADOR PARA FACILITAR LA COMUNICACIóN DE PERSONAS CON DISCAPACIDAD MOTORA DESENHO E CONSTRU O DE UM PROTóTIPO DE INTERFACE CéREBRO-COMPUTADOR PARA FACILITAR A COMUNICA O DE PESSOAS COM INCAPACIDADE MOTORA DESIGN AND CONSTRUCTION OF A BRAIN-COMPUTER INTERFACE PROTOTYPE TO FACILITATE THE COMMUNICATION OF PEOPLE WITH MOTOR DISABILITY.
CAROLINA ARBOLEDA,ELIANA GARCíA,ALEJANDRO POSADA,RóBINSON TORRES
Revista EIA , 2009,
Abstract: Una interfaz cerebro-computador (ICC) es un sistema de comunicación que permite generar una se al de control a partir de se ales cerebrales como los ritmos sensorimotores y los potenciales evocados y, por consiguiente, constituye una alternativa novedosa de comunicación para personas con discapacidad motora seria (como aquellas que padecen esclerosis lateral amiotrófica, ELA). Este proyecto propone el desarrollo de un prototipo de ICC basado en el registro de potenciales evocados cognitivos P-300 mediante electroencefalografía. El prototipo usa un electroencefalógrafo de seis canales para la adquisición de las se ales, y por medio de una matriz de estimulación visual que contiene las letras del abecedario e íconos asociados a ellas permite que el usuario escriba palabras o elabore mensajes con los íconos. Para procesar las se ales (filtración, diezmado, entre otros) se utilizaron los programas BCI2000 y MATLAB 7.0. Este último se empleó para programar tres algoritmos lineales de traslación (análisis lineal del discriminante, solución por mínimos cuadrados y análisis lineal del discriminante paso a paso) que permitieran traducir los potenciales evocados en se ales de comunicación. Uma interface cérebro-computador (ICC) é um sistema de comunica o que permite gerar um sinal de controle a partir de sinais cerebrais como os ritmos sensorimotores e os potenciais evocados e, por conseguinte, constitui uma alternativa nova de comunica o para pessoas com incapacidade motora séria (como aquelas que padecem esclerose lateral amiotrófica, ELA). Este projeto prop e o desenvolvimento de um protótipo de ICC baseado no registro de potenciais evocados cognitivos P-300 mediante electroencefalografia. O protótipo desenvolvido há uso de um electroencefalógrafo de seis canais para a aquisi o dos sinais, e por meio de uma matriz de estimula o visual que contém as letras do abecedário e ícones associados a elas permite que o usuário escreva palavras ou elabore mensagens com os ícones. Para processar os sinais (filtragem, dizimado, entre outros) se utilizaram os programas BCI2000 e MATLAB 7.0. Este último se empregou para programar três algoritmos lineais de transla o (análise linear do discriminante, solu o por mínimos quadrados e análise linear do discriminante passo a passo) que permitissem traduzir os potenciais evocados em sinais de comunica o. A brain-computer interface (BCI) is a communication system that translates a brain signal (e.g. sensorimotor rhythms, evoked potentials) into a control signal and, therefore, constitutes an innovative communication alternati
Estudo da intera??o células Vero/PLGA após a modifica??o da superfície por plasma de oxigênio
Esposito, Andrea R.;Lucchesi, Carolina;Ferreira, Betina M. P.;Duek, Eliana A. R.;
Matéria (Rio de Janeiro) , 2007, DOI: 10.1590/S1517-70762007000100021
Abstract: the application of bioreabsorbable polymers as support for cells culture is an alternative method to treat lesions and loss of tissues. the surface modifications of these polymers by plasma is an effective and economical technique to make it more hydrophilic. the aim of this work was to study the interactions between vero cells and plga supports previously treated by oxygen plasma, to increase the surface hydrofilicity. the samples were characterized by contact angle, mev and citochemical analysis. the plasma treatment increased the hydrofilicity, improving the adhesion and cell proliferation, in comparison with the membranes without treatment.
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