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Search Results: 1 - 10 of 10147 matches for " Elena Luciannatelli "
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Low Serum Urate Levels Are Associated to Female Gender in Multiple Sclerosis Patients
Stefano Zoccolella, Carla Tortorella, Pietro Iaffaldano, Vita Direnzo, Mariangela D’Onghia, Elena Luciannatelli, Damiano Paolicelli, Paolo Livrea, Maria Trojano
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0040608
Abstract: Background Urate is a natural antioxidant and may prevent CNS tissue damage and the clinical manifestations of experimental autoimmune encephalitis. Results from clinical studies are conflicting and the contribution of urate to the pathogenesis of Multiple Sclerosis (MS) remains uncertain. Objective To evaluate serum urate levels in MS patients and their relationships with clinical, demographic and MRI variables. Methods Levels of non-fasting serum uric acid and creatinine were determined by an automated enzymatic assay and glomerular filtration rate was assessed in 245 MS patients, in 252 age/sex-matched neurological controls (NC) and in 59 Healthy controls (HC). Results Median serum urate levels did not differ between MS patients (3.8 mg/dL), HC (4.0 mg/dl) and NC (4.0 mg/dL). Serum urate levels were lower in females than in males in all groups (p = <0.0001). In female-MS, serum urate levels (3.2 mg/dL) were lower compared to those in female HC (3.8; p = 0.01) and NC (3.5 mg/dL; p = 0.02), whereas in male-MS they(4.8 mg/dL) did not differ from those in male HC (4.5 mg/dl) and NC (4.8 mg/dL). Urate concentrations trended to be lower in Clinically isolated syndromes suggestive of MS (3.7 mg/dL) and in relapsing MS (3.7 mg/dL), compared to patients with progressive MS (4.4 mg/dL; p = 0.06), and in patients with an annual relapse rate (ARR) >2 (3.3 mg/dL) than in those with an ARR ≤2: 3.9 mg/dL; p = 0.05). Significant lower serum urate levels were found in females than in males in all clinical MS subtypes (p<0.01), separately evaluated. Female sex (beta: ?0.53; p<0.00001) was the most significant determinant of serum urate concentrations in MS patients on multivariate regression analysis. Conclusions Our findings suggest that low urate levels could be of significance in predominantly inflammatory phases of MS even at the early stage and mainly in females.
New Value-Behavioral Structures and Hierarchies in the Technical Academic Education in the Context of Romania Integration in the European Union  [PDF]
Tiron Elena
Sociology Mind (SM) , 2011, DOI: 10.4236/sm.2011.12009
Abstract: The work is structured in 4 parts: I. Conceptual differentiations: value, belief, norm, mentality, attitude, interest, opinion, need, behavior; II. Restructuring scheme of the personality axiological components in a determined context; III. Professional values in the technical academic education: identification and hierarchy; IV. Conclu- sions. In the first part, there are made conceptual differentiations between the notions of belief, norm, mentality, attitude, interest, opinion, need, behavior, emphasizing thus on mutual aspects. In the second part of the paper, there is presented the global structuring of the axiological universe, the determinant factors of the value hierar- chy change in a given social-economic context, there is elaborated a new re-structuring scheme of the value components, there are identified specific mechanisms to the present Romanian society resistant to the value au- thentic change. In the third part, there is described D. E. Super’s theory that stands at the basis of the elaboration of the Professional Value Inventory. This was applied in our research on a sample of 120 students from the two technical faculties, getting thus a certain professional values hierarchy. The conclusions emphasize the confir- mation of the two hypothesis, the extrinsic motivating factors of the professional choice, behaviors and attitudes definition, values through immediate, material profit, of the individual welfare.
Realization Feature of Mesenchymal Dermal Cells Tissue Engineering Construction Response in Granulating Wound Transplantation in Relation with Time-Frame  [PDF]
Elena Petersen
Journal of Cosmetics, Dermatological Sciences and Applications (JCDSA) , 2012, DOI: 10.4236/jcdsa.2012.23024
Abstract: Derma is progenitor cells sours, that are able to differentiate further in several mesodermal lineage and neural and endodermal lineage. Culture conditions, skin taking site and culture medium composition considerably contribute to it. Spheroid cultured mesenchymal dermal cells contribution to skin regeneration in granulating wound in rat model was estimated.
A Model for Managing Geological and Geophysical Data in Eastern Sicily (Italy) and Possible Applications  [PDF]
Elena Partescano
Journal of Computer and Communications (JCC) , 2014, DOI: 10.4236/jcc.2014.214007
Abstract: The main aim of this work is to describe in detail how to develop an instrument, with the goal of collecting and managing a great deal of both geological and geophysical data acquired using different survey typologies in Eastern Sicily (Italy). The opportunity to manage different categories of data, at the same time, allows us to have a complete view of the complex area studied. This paper discusses a software package that has been designed to enhance the efficiency of applying a range of geological and geophysical data. More than 12000 records are archived: boreholes represent 81% of the data and 19% is geophysical data. In this paper it is illustrated how both kinds of data, thanks to the functionalities of the database and the possibility of connecting to a Geographical Information System (GIS), can be used in a variety of different geological studies. We present four studies where is relevant the use of the database, in detail, we show a morpho-structural study, an examination of the spectral analysis of the noise data, an update of the geological and geotechnical maps, and a classification of the areas on the basis of the distribution of the shear wave velocity in the firsts 30 meters (Vs30). They are just some examples of the potentialities of a relational database.
Knowledge-Based Economy as a Basis for the Long-Term Strategy of the Development of the Society  [PDF]
Elena Pilipenko
Modern Economy (ME) , 2015, DOI: 10.4236/me.2015.68084
Abstract: This article is devoted to the research of theoretical and methodological aspects of economy of knowledge formation. The emphasis is laid on the evolution of knowledge as the main reason of any changes which take place in the society. Scientific knowledge is considered as the key resource of creating social wealth; and the process of its production—as an indissoluble processing chain which consists of spiritual, informative and material production. Such approach brings about the necessity of drastic review of the whole system of economic categories and grounds in it models, methods, criteria and exponents. Authorial conception of economy of knowledge is suggested. It is based on three main principles: 1) the unity of economic field; 2) preferred development of spiritual production; 3) accordance of controlling mechanism and effectiveness exponents to the peculiarities of goods of any production.
Risks of Related Parties in Transition Economy—An Audit Approach  [PDF]
Elena Dobre
Open Journal of Accounting (OJAcct) , 2017, DOI: 10.4236/ojacct.2017.63008
Abstract:
This paper aims at improving audit practices, at least, for our national audit practitioners. Such possibilities are discussed as case study regarding an audit of a public entity as a related party (relationship & transactions) with a private company. This reveals a fraud risk by periodical re-negotiating of significant contracts combined with internal controls deficiency. In order to avoid and remove such bad practices, the Romanian financial auditors, fraud examiners, taxation consultants and even legal advisers, need rigorous learning and professional development and adequate evaluation frameworks, combining in a competent responsible manner quantitative and qualitative evaluation made by a peer-review schema. Exclusive quantitative approaches are not adequate for a correct evaluation. An efficient evaluation must involve human specialists, including financial auditor’s colleagues. The results for entire professional body may result in higher quality judgments and a good assimilation; not only good practice international standards, but even entire experience of practitioners in this field was recommended. Emphasizing of professional skepticism arises with enough experience.
Using an Interactive Computer System to Support the Task of Building the Notions of Ratio and Proportion  [PDF]
Elena Fabiola Ruiz Ledesma
Creative Education (CE) , 2010, DOI: 10.4236/ce.2010.12017
Abstract: This article describes the design and general outcome of applying a computer system that includes interactive activities to the topics of ratio and proportion. The work was undertaken with Mexican students attending primary school grade six (11 year olds). In designing the activities, our work was based on the studies of researchers who have focused on such topics, as well as on the work of researchers in the field of computer sciences and education technology. Support of the activities designed is found in psycho-pedagogy, in knowledge of mathematics and in the fields of computer sciences and education technology.
Limited Bandwidths and Correlation Ambiguities: Do They Co-Exist in Galileo Receivers  [PDF]
Elena Simona Lohan
Positioning (POS) , 2011, DOI: 10.4236/pos.2011.21002
Abstract: Galileo is the Global Navigation Satellite System that Europe is building and it is planned to be operational in the next 3-5 years. Several Galileo signals use split-spectrum modulations, such as Composite Binary Offset Carrier (CBOC) modulation, which create correlation ambiguities when processed with large or infinite front-end bandwidths (i.e., in wideband receivers). The correlation ambiguities refer to the notches in the correlation shape (i.e., in the envelope of the correlation between incoming signal and reference modulated code) which happen within +/– 1 chip from the main peak. These correlation ambiguities affect adversely the detection probabilities in the code acquisition process and are usually dealt with by using some form of unambiguous processing (e.g., BPSK-like techniques, sideband processing, etc.). In some applications, such as mass-market applications, a narrowband Galileo receiver (i.e., with considerable front-end bandwidth limitation) is likely to be employed. The question addressed in this paper, which has not been answered before, is whether or not this bandwidth limitation can cope inherently with the ambiguities of the correlation function, to which extent, and which the best design options are in the acquisition process (e.g., in terms of time-bin step and ambiguity mitigation mechanisms).
Representation Registers in the Solution of Calculus Problems  [PDF]
Elena Fabiola Ruiz Ledesma
Creative Education (CE) , 2011, DOI: 10.4236/ce.2011.23036
Abstract: This article is derived from the research project registered under number 20110343 (Ruiz, 2011), and developed in Escuela Superior de Cómputo del Instituto Politécnico Nacional (IPN) (School of Computer Sciences of the National Poly-technical Institute of Mexico). The article reports on the problems found among Engineering students with respect to their resistance to using different representation registers when solving optimization problems in the Calculus Learning Unit. Use of such registers could help the students to build mathematics know ledge and to solve calculus problems. As a didactic strategy, simulations are used in an electronic environment in order to support the students by fostering their use of tabular, graphical and algebraic representation registers. Interviews are undertaken of six of the professors who give the calculus courses, and a diagnostic questionnaire is applied to 68 students prior to and after working with the proposal. As for the theoretical framework, the work reported by Duval and Hitt is salient in this report, particularly their emphasis of the fact that working on activities by way of one single representation system is not sufficient. From the first responses provided by the students, one can conclude that the algebraic register is preferred by the majority of students. It is however used in a mechanical fashion without affording any meaning to the content of the problem and to the process of solving it. Another conclusion reported is that implementing tasks in the classroom in which the mathematics activity requires coherent use of different representations is necessary.
Primary and Secondary Teachers’ Knowledge, Interpretation, and Approaches to Students Errors about Ratio and Proportion Topics  [PDF]
Elena Fabiola Ruiz Ledesma
Creative Education (CE) , 2011, DOI: 10.4236/ce.2011.23035
Abstract: This study investigated elementary and secondary teachers’ understanding and pedagogical strategies applied to students making errors in finding a missing length in similar rectangles. It was revealed that secondary teachers had better understanding of ratio and proportion in similar rectangles than elementary teachers. While all secondary teachers solved the similar rectangles problems correctly, a large portion of elementary teacher struggled with the problem. In explaining their solution strategies, and even though similar strategies appeared both from elementary teachers and secondary teachers, a majority of secondary teachers pointed out the underlying idea of similarity, whereas less than half of the elementary teachers explained their reasoning for using ratios and proportion. This article is derived from the research project registered under number 20110343 (Ruiz, 2011), and developed in Escuela Superior de Cómputo del Instituto Politécnico Nacional (IPN) (School of Computer Sciences of the National Poly-technical Institute of Mexico)
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