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Search Results: 1 - 10 of 488576 matches for " Elba Cristina Sá de Camargo;LIMA "
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Gallium-67 imaging in a patient with paracoccidioidomycosis: a case report
TEIXEIRA Ana Beatriz Marinho de Jesus,ETCHEBEHERE Elba Cristina Sá de Camargo,LIMA Mariana Cunha Lopes de,SANTOS Allan de Oliveira
Revista do Instituto de Medicina Tropical de S?o Paulo , 2000,
Abstract: A 26 year-old female was admitted with abdominal pain, fever and weight loss. The clinical and laboratory investigations led to the diagnosis of paracoccidioidomycosis. Gallium-67 whole body images correlated well with the clinical course of the disease and with the patient's prognosis.
Estimation of absolute renal uptake with technetium-99m dimercaptosuccinic acid: direct comparison with the radioactivity of nephrectomy specimens
Lima, Mariana da Cunha Lopes de;Ramos, Celso Darío;Brunetto, Sérgio Quirino;Lima, Marcelo Lopes de;Ferreira, Ubirajara;Etchebehere, Elba Cristina Sá Camargo;Santos, Allan de Oliveira;Netto Júnior, Nelson Rodrigues;Camargo, Edwaldo Eduardo;
Sao Paulo Medical Journal , 2008, DOI: 10.1590/S1516-31802008000300003
Abstract: context and objective: studies using radionuclides are the most appropriate method for estimating renal function. dimercaptosuccinic acid chelate labeled with technetium-99m (99mtc-dmsa) is the radiopharmaceutical of choice for high-resolution imaging of the renal cortex and estimation of the functional renal mass. the aim of this study was to evaluate a simplified method for determining the absolute renal uptake (aru) of 99mtc-dmsa prior to nephrectomy, using the radioactivity counts of nephrectomy specimens as the gold standard. design and setting: prospective study at the division of nuclear medicine, department of radiology, universidade estadual de campinas. methods: seventeen patients (12 females; range 22-82 years old; mean age 50.8 years old) underwent nephrectomy for various reasons. renal scintigraphy was performed three to four hours after intravenous administration of a mean dose of 188.7 mbq (5.1 mci) of 99mtc-dmsa, which was done six to 24 hours before surgery. the in vivo renal uptake of 99mtc-dmsa was determined using the radioactivity of the syringe before the injection (measured using a dose calibrator) and the images of the syringe and kidneys, obtained from a scintillation camera. after surgery, the reference value for renal uptake of 99mtc-dmsa was determined by measuring the radioactivity of the nephrectomy specimen using the same dose calibrator. results: the aru measurements were very similar to those obtained using the reference method, as determined by linear regression (r-squared = 0.96). conclusion: aru estimation using the proposed method before nephrectomy seems to be accurate and feasible for routine use.
Gallium-67 imaging in a patient with paracoccidioidomycosis: a case report
TEIXEIRA, Ana Beatriz Marinho de Jesus;ETCHEBEHERE, Elba Cristina Sá de Camargo;LIMA, Mariana Cunha Lopes de;SANTOS, Allan de Oliveira;PIRES, Bruno Cunha;VALEN?A JR., José Telmo;RAMOS, Celso Darío;CAMARGO, Edwaldo E.;
Revista do Instituto de Medicina Tropical de S?o Paulo , 2000, DOI: 10.1590/S0036-46652000000300011
Abstract: a 26 year-old female was admitted with abdominal pain, fever and weight loss. the clinical and laboratory investigations led to the diagnosis of paracoccidioidomycosis. gallium-67 whole body images correlated well with the clinical course of the disease and with the patient's prognosis.
Functional electrical stimulation improves brain perfusion in cranial trauma patients
Amorim, Bárbara Juarez;Santos, Allan de Oliveira;Oberg, Telma Dagmar;Romanato, Juliana;Anjos, Dalton A.;Lima, Mariana da Cunha Lopes de;Ramos, Celso Darío;Honorato, Donizete Cesar;Camargo, Edwaldo Eduardo;Etchebehere, Elba Cristina de Sá Camargo;
Arquivos de Neuro-Psiquiatria , 2011, DOI: 10.1590/S0004-282X2011000500020
Abstract: objective: demonstrate brain perfusion changes due to neuronal activation after functional electrical stimulation (fes). method: it was studied 14 patients with hemiplegia who were submitted to a program with fes during fourteen weeks. brain perfusion spect was performed before and after fes therapy. these patients were further separated into 2 groups according to the hemiplegia cause: cranial trauma and major vascular insults. all spect images were analyzed using spm. results: there was a significant statistical difference between the two groups related to patient's ages and extent of hypoperfusion in the spect. patients with cranial trauma had a reduction in the hypoperfused area and patients with major vascular insult had an increase in the hypoperfused area after fes therapy. conclusion: fes therapy can result in brain perfusion improvement in patients with brain lesions due to cranial trauma but probably not in patients with major vascular insults with large infarct area.
Treatment of bone pain secondary to metastases using samarium-153-EDTMP
Etchebehere, Elba Cristina Sá de Camargo;Pereira Neto, Carlos Araújo Cunha;Lima, Mariana Cunha Lopes de;Santos, Allan de Oliveira;Ramos, Celso Darío;Silva, Cleide Maria;Camargo, Edwaldo Eduardo;
Sao Paulo Medical Journal , 2004, DOI: 10.1590/S1516-31802004000500006
Abstract: context: more than 50% of patients with prostate, breast or lung cancer will develop painful bone metastases. the purpose of treating bone metastases is to relieve pain, reduce the use of steroids and to maintain motion. objective: to evaluate the use of samarium-153-edtmp (153sm-edtmp) for the treatment of bone pain secondary to metastases that is refractory to clinical management. type of study: retrospective. setting: division of nuclear medicine, universidade estadual de campinas (unicamp). methods: fifty-eight patients were studied (34 males) with mean age 62 years; 31 patients had prostate cancer, 20 had breast cancer, three had lung cancer, one had lung hemangioendothelioma, one had parathyroid adenocarcinoma, one had osteosarcoma and one had an unknown primary tumor. all patients had multiple bone metastases demonstrated by bone scintigraphy using 99mtc-mdp,and were treated with 153sm-edtmp. response to treatment was graded as good (pain reduction of 50-100%), intermediate (25-49%) and poor (0-24%). results: all patients showed good uptake of 153sm-edtmp by bone metastases. among the patients with prostate cancer, intermediate or good response to therapy occurred in 80.6% (25 patients) and poor response in 19.4% (6). among the patients with breast cancer, 85% (17) showed intermediate or good response to therapy while 15% (3) showed poor response. all three patients with lung cancer showed poor response to treatment. the lung hemangioendothelioma and unknown primary lesion patients showed intermediate response to treatment; the osteosarcoma and parathyroid adenocarcinoma patients showed good response to treatment. no significant myelotoxicity occurred. discussion: pain control is important for improving the quality of life of patients with advanced cancers. the mechanism by which pain is relieved with the use of radionuclides is still not yet completely understood, however, the treatment is simple and provides a low risk of mielotoxicity. conclusion: treatmen
Low sensitivity of three-phase bone scintigraphy for the diagnosis of repetitive strain injury
Amorim, Bárbara Juarez;Etchebehere, Elba Cristina Sá de Camargo;Torre, Graciella Dalla;Lima, Mariana da Cunha Lopes de;Santos, Allan de Oliveira;Ramos, Celso Darío;Gonzalez, Luiz Ricardo;Oliveira, José Inácio;Camargo, Edwaldo Eduardo;
Sao Paulo Medical Journal , 2006, DOI: 10.1590/S1516-31802006000300007
Abstract: context and objective: the diagnosis of repetitive strain injury (rsi) is subjective and solely based on clinical signs and physical examination. the aim of this paper was to assess the usefulness of three-phase bone scintigraphy (tpbs) in diagnosing rsi. design and setting: prospective study at the division of nuclear medicine, department of radiology, school of medical sciences, universidade estadual de campinas (unicamp). methods: seventy-three patients (mean age 31.2 years; 47 males) with clinical suspicion of rsi in the upper limbs were studied. a total of 127 joints with suspicion of rsi were studied. the shoulders, elbows and wrists were analyzed semi-quantitatively, using the shafts of the humeri and ulnae as references. the results were compared with a control group of 40 normal individuals. the patients? signs and symptoms were used as the "gold standard" for calculating the probabilities. results: from visual analysis, abnormalities were observed in the flow phase for four joints, in the blood pool phase for 11 joints and in the delayed images for 26 joints. visual analysis of the joints of the control group did not show any abnormalities. semi-quantitative analysis showed that most of the patients? joint ratios were normal. the exceptions were the wrists of patients with left-sided rsi (p = 0.0216). however, the sensitivity (9%) and accuracy (41%) were very low. conclusion: tpbs with semi-quantitative analysis has very low sensitivity and accuracy in the detection of rsi abnormalities in the upper limbs.
Brain SPECT in mesial temporal lobe epilepsy: comparison between visual analysis and SPM
Amorim, Bárbara Juarez;Ramos, Celso Darío;Santos, Allan Oliveira dos;Lima, Mariana da Cunha Lopes de;Min, Li Li;Camargo, Edwaldo Eduardo;Cendes, Fernando;Etchebehere, Elba Cristina Sá de Camargo;
Arquivos de Neuro-Psiquiatria , 2010, DOI: 10.1590/S0004-282X2010000200001
Abstract: objective: to compare the accuracy of spm and visual analysis of brain spect in patients with mesial temporal lobe epilepsy (mtle). method: interictal and ictal spects of 22 patients with mtle were performed. visual analysis were performed in interictal (visual(inter)) and ictal (visual(ictal/inter)) studies. spm analysis consisted of comparing interictal (spm(inter)) and ictal spects (spm(ictal)) of each patient to control group and by comparing perfusion of temporal lobes in ictal and interictal studies among themselves (spm(ictal/inter)). results: for detection of the epileptogenic focus, the sensitivities were as follows: visual(inter)=68%; visual(ictal/inter)=100%; spm(inter)=45%; spm(ictal)=64% and spm(ictal/inter)=77%. spm was able to detect more areas of hyperperfusion and hypoperfusion. conclusion: spm did not improve the sensitivity to detect epileptogenic focus. however, spm detected different regions of hypoperfusion and hyperperfusion and is therefore a helpful tool for better understand pathophysiology of seizures in mtle.
Avalia??o pré-cirúrgica de epilepsia neocortical de lobo temporal com utiliza??o de FDG-18F SPECT: relato de caso
Bilevicius, Elizabeth;Etchebehere, Elba Cristina Sá de Camargo;Camargo, Edwaldo E.;Yasuda, Clarissa L.;Cendes, Fernando;
Journal of Epilepsy and Clinical Neurophysiology , 2006, DOI: 10.1590/S1676-26492006000500010
Abstract: introduction: several patients with partial epilepsies do not present an easily identified epileptogenic focus on scalp eeg or visible lesion on mri. there are some useful functional neuroimaging techniques that could be considered in these cases, such as interictal positron emission tomography (pet) scan and ictal single-photon emission computed tomography (spect). these techniques can guide the placement of deep electrodes or even prevent their use in some situations. unfortunately, pet scanners are not easily available in a great number of epilepsy centers because of its cost. objective: to demonstrate that 18f-fdg spect could be a good alternative replacing pet scan on localization of epileptic focus and surgical planning in places where this technology is not available. materials and methods: case report of a patient with refractory neocortical temporal lobe epilepsy, with normal mri and nuclear eeg localization. results: the patient was submitted to interictal 18f-fdg spect scan, that showed hypometabolism in the anterior, mesial and lateral parts of the right temporal lobe. these areas were surgically resected and the patient outcome after 24 moths has been very good (engel ib). conclusion: we suggest that in some situations an interictal 18f-fdg spect scan could replace 18f-fdg pet scan where this technique is not available.
Brain hypoperfusion in adolescents dependent of multiple drugs
Etchebehere, Elba Cristina Sá de Camargo;Oliveira, Felipe Martins;Amorim, Bárbara Juarez;Serrat, Saulo Monte;Camargo, Edwaldo Eduardo;
Arquivos de Neuro-Psiquiatria , 2010, DOI: 10.1590/S0004-282X2010000200002
Abstract: brain spect imaging (bsi) with statistical parametric mapping (spm) offers a clear and accurate vision of perfusion changes. objective: to study brain perfusion abnormalities in adolescents' dependent of multiple drugs. method: sixteen male patients (15.1±2.1 years) were submitted to 99mtc-hmpao bsi with spm. results: cortical hypoperfusion occurred in 7/16 patients (44%). there was a significant inverse correlation between the number of hypoperfused regions and the patient's age (p= -0.6737; p=0.004) and with the age when the drug dependence began (p= -0.5616; p=0.023). there was also a tendency towards an inverse correlation between regions of hypoperfusion and the duration of the drug dependence. conclusion: bsi with spm can help detect hypoperfusion in adolescents dependent on multiple drugs. the younger the patients, the more regions of hypoperfusion are noted. probably, the neuronal plasticity has an important role in this phenomenon because the highest neural activity occurs in childhood.
Statistical voxel-wise analysis of ictal SPECT reveals pattern of abnormal perfusion in patients with temporal lobe epilepsy
Amorim, Bárbara Juarez;Etchebehere, Elba Cristina Sá de Camargo;Camargo, Edwaldo Eduardo;Rio, Pablo Augusto;Bonilha, Leonardo;Rorden, Chris;Li, Li Min;Cendes, Fernando;
Arquivos de Neuro-Psiquiatria , 2005, DOI: 10.1590/S0004-282X2005000600014
Abstract: objective: to investigate the pattern of perfusion abnormalities in ictal and interictal brain perfusion spect images (bsi) from patients with temporal lobe epilepsy (tle). method: it was acquired interictal and ictal bsi from 24 patients with refractory tle. bsis were analyzed by visual inspection and statistical parametric mapping (spm2). statistical analysis compared the patients group to a control group of 50 volunteers. the images from patients with left-tle were left-right flipped. results: it was not observed significant perfusional differences in interictal scans with spm. ictal bsi in spm analysis revealed hyperperfusion within ipsilateral temporal lobe (epileptogenic focus) and also contralateral parieto-occipital region, ipsilateral posterior cingulate gyrus, occipital lobes and ipsilateral basal ganglia. ictal bsi also showed areas of hypoperfusion. conclusion: in a group analysis of ictal bsi of patients with tle, voxel-wise analysis detects a network of distant regions of perfusional alteration which may play active role in seizure genesis and propagation.
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