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Search Results: 1 - 10 of 483784 matches for " Elba Cristina Sá de Camargo;Camargo "
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Avalia??o pré-cirúrgica de epilepsia neocortical de lobo temporal com utiliza??o de FDG-18F SPECT: relato de caso
Bilevicius, Elizabeth;Etchebehere, Elba Cristina Sá de Camargo;Camargo, Edwaldo E.;Yasuda, Clarissa L.;Cendes, Fernando;
Journal of Epilepsy and Clinical Neurophysiology , 2006, DOI: 10.1590/S1676-26492006000500010
Abstract: introduction: several patients with partial epilepsies do not present an easily identified epileptogenic focus on scalp eeg or visible lesion on mri. there are some useful functional neuroimaging techniques that could be considered in these cases, such as interictal positron emission tomography (pet) scan and ictal single-photon emission computed tomography (spect). these techniques can guide the placement of deep electrodes or even prevent their use in some situations. unfortunately, pet scanners are not easily available in a great number of epilepsy centers because of its cost. objective: to demonstrate that 18f-fdg spect could be a good alternative replacing pet scan on localization of epileptic focus and surgical planning in places where this technology is not available. materials and methods: case report of a patient with refractory neocortical temporal lobe epilepsy, with normal mri and nuclear eeg localization. results: the patient was submitted to interictal 18f-fdg spect scan, that showed hypometabolism in the anterior, mesial and lateral parts of the right temporal lobe. these areas were surgically resected and the patient outcome after 24 moths has been very good (engel ib). conclusion: we suggest that in some situations an interictal 18f-fdg spect scan could replace 18f-fdg pet scan where this technique is not available.
Brain hypoperfusion in adolescents dependent of multiple drugs
Etchebehere, Elba Cristina Sá de Camargo;Oliveira, Felipe Martins;Amorim, Bárbara Juarez;Serrat, Saulo Monte;Camargo, Edwaldo Eduardo;
Arquivos de Neuro-Psiquiatria , 2010, DOI: 10.1590/S0004-282X2010000200002
Abstract: brain spect imaging (bsi) with statistical parametric mapping (spm) offers a clear and accurate vision of perfusion changes. objective: to study brain perfusion abnormalities in adolescents' dependent of multiple drugs. method: sixteen male patients (15.1±2.1 years) were submitted to 99mtc-hmpao bsi with spm. results: cortical hypoperfusion occurred in 7/16 patients (44%). there was a significant inverse correlation between the number of hypoperfused regions and the patient's age (p= -0.6737; p=0.004) and with the age when the drug dependence began (p= -0.5616; p=0.023). there was also a tendency towards an inverse correlation between regions of hypoperfusion and the duration of the drug dependence. conclusion: bsi with spm can help detect hypoperfusion in adolescents dependent on multiple drugs. the younger the patients, the more regions of hypoperfusion are noted. probably, the neuronal plasticity has an important role in this phenomenon because the highest neural activity occurs in childhood.
Statistical voxel-wise analysis of ictal SPECT reveals pattern of abnormal perfusion in patients with temporal lobe epilepsy
Amorim, Bárbara Juarez;Etchebehere, Elba Cristina Sá de Camargo;Camargo, Edwaldo Eduardo;Rio, Pablo Augusto;Bonilha, Leonardo;Rorden, Chris;Li, Li Min;Cendes, Fernando;
Arquivos de Neuro-Psiquiatria , 2005, DOI: 10.1590/S0004-282X2005000600014
Abstract: objective: to investigate the pattern of perfusion abnormalities in ictal and interictal brain perfusion spect images (bsi) from patients with temporal lobe epilepsy (tle). method: it was acquired interictal and ictal bsi from 24 patients with refractory tle. bsis were analyzed by visual inspection and statistical parametric mapping (spm2). statistical analysis compared the patients group to a control group of 50 volunteers. the images from patients with left-tle were left-right flipped. results: it was not observed significant perfusional differences in interictal scans with spm. ictal bsi in spm analysis revealed hyperperfusion within ipsilateral temporal lobe (epileptogenic focus) and also contralateral parieto-occipital region, ipsilateral posterior cingulate gyrus, occipital lobes and ipsilateral basal ganglia. ictal bsi also showed areas of hypoperfusion. conclusion: in a group analysis of ictal bsi of patients with tle, voxel-wise analysis detects a network of distant regions of perfusional alteration which may play active role in seizure genesis and propagation.
Thyroid uptake and scintigraphy using 99mTc pertechnetate: standardization in normal individuals
Ramos, Celso Darío;Wittmann, Denise Engelbrecht Zantut;Etchebehere, Elba Cristina Sá de Camargo;Tambascia, Marcos Antonio;Silva, Cleide Aparecida Moreira;Camargo, Edwaldo Eduardo;
Sao Paulo Medical Journal , 2002, DOI: 10.1590/S1516-31802002000200004
Abstract: context: thyroid uptake and scintigraphy using 99mtc-pertechnetate has proven to be more advantageous than with 131i-iodide, since the images have better quality, the procedure is faster and the patient is submitted to a lower radiation dose. objective: the purpose of this study was to standardize a simple and fast methodology for performing thyroid uptake and scintigraphy and to determine the normal values for 99mtc- pertechnetate uptake. type of study: prospective, non-randomized. setting: division of nuclear medicine, department of radiology, school of medical sciences, campinas state university. participants: the study consisted of 47 normal individuals, 30 women and 17 men, with ages ranging from 19 to 61 years (mean of 33 years). procedures: the laboratory assessment of thyroid function consisted of serum dosages of ultra-sensitive thyroxin and thyrotrophin. twenty minutes after an intravenous injection of 10 mci (370 mbq) of 99mtc-pertechnetate, the images were obtained on a computerized scintillation camera equipped with a low-energy high-resolution parallel hole collimator. results: all the individuals were euthyroid both on clinical and laboratory evaluation. the baseline thyroid 99mtc-pertechnetate uptake ranged from 0.4 to 1.7%. the uptake values obtained in these normal individuals showed that 95% presented a thyroid uptake that ranged from 0.4 to 1.5% of the injected dose. conclusion: the assessment of thyroid structure and function using 99mtc-pertechnetate is a simple, fast and efficient method, which could easily become a part of the routine studies in nuclear medicine laboratories.
Gallium-67 imaging in a patient with paracoccidioidomycosis: a case report
TEIXEIRA Ana Beatriz Marinho de Jesus,ETCHEBEHERE Elba Cristina Sá de Camargo,LIMA Mariana Cunha Lopes de,SANTOS Allan de Oliveira
Revista do Instituto de Medicina Tropical de S?o Paulo , 2000,
Abstract: A 26 year-old female was admitted with abdominal pain, fever and weight loss. The clinical and laboratory investigations led to the diagnosis of paracoccidioidomycosis. Gallium-67 whole body images correlated well with the clinical course of the disease and with the patient's prognosis.
Estimation of absolute renal uptake with technetium-99m dimercaptosuccinic acid: direct comparison with the radioactivity of nephrectomy specimens
Lima, Mariana da Cunha Lopes de;Ramos, Celso Darío;Brunetto, Sérgio Quirino;Lima, Marcelo Lopes de;Ferreira, Ubirajara;Etchebehere, Elba Cristina Sá Camargo;Santos, Allan de Oliveira;Netto Júnior, Nelson Rodrigues;Camargo, Edwaldo Eduardo;
Sao Paulo Medical Journal , 2008, DOI: 10.1590/S1516-31802008000300003
Abstract: context and objective: studies using radionuclides are the most appropriate method for estimating renal function. dimercaptosuccinic acid chelate labeled with technetium-99m (99mtc-dmsa) is the radiopharmaceutical of choice for high-resolution imaging of the renal cortex and estimation of the functional renal mass. the aim of this study was to evaluate a simplified method for determining the absolute renal uptake (aru) of 99mtc-dmsa prior to nephrectomy, using the radioactivity counts of nephrectomy specimens as the gold standard. design and setting: prospective study at the division of nuclear medicine, department of radiology, universidade estadual de campinas. methods: seventeen patients (12 females; range 22-82 years old; mean age 50.8 years old) underwent nephrectomy for various reasons. renal scintigraphy was performed three to four hours after intravenous administration of a mean dose of 188.7 mbq (5.1 mci) of 99mtc-dmsa, which was done six to 24 hours before surgery. the in vivo renal uptake of 99mtc-dmsa was determined using the radioactivity of the syringe before the injection (measured using a dose calibrator) and the images of the syringe and kidneys, obtained from a scintillation camera. after surgery, the reference value for renal uptake of 99mtc-dmsa was determined by measuring the radioactivity of the nephrectomy specimen using the same dose calibrator. results: the aru measurements were very similar to those obtained using the reference method, as determined by linear regression (r-squared = 0.96). conclusion: aru estimation using the proposed method before nephrectomy seems to be accurate and feasible for routine use.
Gallium-67 imaging in a patient with paracoccidioidomycosis: a case report
TEIXEIRA, Ana Beatriz Marinho de Jesus;ETCHEBEHERE, Elba Cristina Sá de Camargo;LIMA, Mariana Cunha Lopes de;SANTOS, Allan de Oliveira;PIRES, Bruno Cunha;VALEN?A JR., José Telmo;RAMOS, Celso Darío;CAMARGO, Edwaldo E.;
Revista do Instituto de Medicina Tropical de S?o Paulo , 2000, DOI: 10.1590/S0036-46652000000300011
Abstract: a 26 year-old female was admitted with abdominal pain, fever and weight loss. the clinical and laboratory investigations led to the diagnosis of paracoccidioidomycosis. gallium-67 whole body images correlated well with the clinical course of the disease and with the patient's prognosis.
Deposi??o pulmonar de tobramicina inalatória antes e após fisioterapia respiratória e uso de salbutamol inalatório em pacientes com fibrose cística colonizados por Pseudomonas aeruginosa
Grotta, Milena Baptistella;Etchebere, Elba Cristina de Sá Camargo;Ribeiro, Antonio Fernando;Romanato, Juliana;Ribeiro, Maria ?ngela Gon?alves de Oliveira;Ribeiro, José Dirceu;
Jornal Brasileiro de Pneumologia , 2009, DOI: 10.1590/S1806-37132009000100006
Abstract: objective: to evaluate whether respiratory therapy followed by the use of inhaled albuterol modifies the pulmonary deposition of inhaled tobramycin in patients with cystic fibrosis (cf) and whether pulmonary deposition correlates with disease severity or genotype. methods: a prospective study was carried out including patients with cf older than 6 years of age and colonized with pseudomonas aeruginosa. exclusion criteria were pulmonary exacerbation, changes in therapy between the study phases and fev1 < 25%. all patients were submitted to pulmonary scintigraphy by means of a scintillation camera equipped with a low energy all purpose collimator in order to evaluate drug penetration following the administration of inhaled 99mtc-tobramycin, as well as to pulmonary perfusion with 99mtc-macroaggregated albumin (phase 1). one month later, the same procedure was performed following respiratory therapy and administration of inhaled albuterol (phase 2). results: we included 24 patients (12 males) aged 5-27 years (mean ± sd: 12.85 ± 6.64 years). the shwachman score (ss) was excellent/good in 8 patients, moderate/fair in 16 and poor in 0. genotyping revealed that 7 patients were δf508 homozygotes, 13 were δf508 heterozygotes; and 4 presented other mutations. in all patients, lung deposition of tobramycin decreased in phase 2, especially in those with moderate/fair ss (p = 0.017) and in heterozygotes (p = 0.043). conclusions: the use of a respiratory therapy technique and the administration of inhaled albuterol immediately prior to the use of inhaled tobramycin decreased the pulmonary deposition of the latter in cf patients, and this reduction correlates with disease severity and genotype.
Neuropsychological and phonological evaluation in the Apert's syndrome: study of two cases
Ciasca, Sylvia Maria;Araujo, Ana Paula;Sim?o, Adriana Nobre de Paula;Capellini, Simone Aparecida;Chiaratti, Paula Scalla;Camargo, Edwaldo Eduardo;Santos, Allan de Oliveira;Camargo, Elba Cristina Sá de;
Arquivos de Neuro-Psiquiatria , 2001, DOI: 10.1590/S0004-282X2001000300006
Abstract: this study evaluated two cases of apert's syndrome, through phonological, cognitive, and neuropsychological instruments and correlated the results to complementary exams. in short, this study reveals the necessity of application of neuropsychological, cognitive and phonological evaluation and correlation of the results with complementary testings because significant differences can be present in the apert's syndrome.
Functional electrical stimulation improves brain perfusion in cranial trauma patients
Amorim, Bárbara Juarez;Santos, Allan de Oliveira;Oberg, Telma Dagmar;Romanato, Juliana;Anjos, Dalton A.;Lima, Mariana da Cunha Lopes de;Ramos, Celso Darío;Honorato, Donizete Cesar;Camargo, Edwaldo Eduardo;Etchebehere, Elba Cristina de Sá Camargo;
Arquivos de Neuro-Psiquiatria , 2011, DOI: 10.1590/S0004-282X2011000500020
Abstract: objective: demonstrate brain perfusion changes due to neuronal activation after functional electrical stimulation (fes). method: it was studied 14 patients with hemiplegia who were submitted to a program with fes during fourteen weeks. brain perfusion spect was performed before and after fes therapy. these patients were further separated into 2 groups according to the hemiplegia cause: cranial trauma and major vascular insults. all spect images were analyzed using spm. results: there was a significant statistical difference between the two groups related to patient's ages and extent of hypoperfusion in the spect. patients with cranial trauma had a reduction in the hypoperfused area and patients with major vascular insult had an increase in the hypoperfused area after fes therapy. conclusion: fes therapy can result in brain perfusion improvement in patients with brain lesions due to cranial trauma but probably not in patients with major vascular insults with large infarct area.
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