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Search Results: 1 - 10 of 309 matches for " Eiichiro Tominaga "
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Oncofertility in Gynecologic Malignant Tumors  [PDF]
Masataka Adachi, Kouji Banno, Iori Kisu, Megumi Yanokura, Moito Iijima, Takashi Takeda, Kiyoko Umene, Yuya Nogami, Eiichiro Tominaga, Daisuke Aoki
Journal of Cancer Therapy (JCT) , 2015, DOI: 10.4236/jct.2015.614128
Abstract: Long-term survival is the priority in treatment of patients with malignant tumors. In the field of gynecology, fertility preservation has also recently become an important objective due to improved treatment outcomes and different needs of patients. Methods for fertility preservation include cervical conization, ovarian protection against radiation or chemotherapy for ovarian cancer since the ovary is hypersensitive to cancer therapies, treatment of gynecological cancer during pregnancy, and cryopreservation of oocytes, embryos or ovarian tissue before treatment of malignant tumors. Radical trachelectomy for early cervical cancer and treatment with medroxy progesterone acetate for early endometrial carcinoma are also options for fertility preservation, but the efficacy and risk of recurrence have yet to be fully evaluated. The first childbirth following uterine transplantation was also achieved last year and this success has expanded the potential for pregnancy and delivery among cancer survivors.
Hunting for Primordial Non-Gaussianity in the Cosmic Microwave Background
Eiichiro Komatsu
Physics , 2010, DOI: 10.1088/0264-9381/27/12/124010
Abstract: Since the first limit on the (local) primordial non-Gaussianity parameter, fNL, was obtained from COBE data in 2002, observations of the CMB have been playing a central role in constraining the amplitudes of various forms of non-Gaussianity in primordial fluctuations. The current 68% limit from the 7-year WMAP data is fNL=32+/-21, and the Planck satellite is expected to reduce the uncertainty by a factor of four in a few years from now. If fNL>>1 is found by Planck with high statistical significance, all single-field models of inflation would be ruled out. Moreover, if the Planck satellite finds fNL=30, then it would be able to test a broad class of multi-field models using the four-point function (trispectrum) test of tauNL>=(6fNL/5)^2. In this article, we review the methods (optimal estimator), results (WMAP 7-year), and challenges (secondary anisotropy, second-order effect, and foreground) of measuring primordial non-Gaussianity from the CMB data, present a science case for the trispectrum, and conclude with future prospects.
The Pursuit of Non-Gaussian Fluctuations in the Cosmic Microwave Background
Eiichiro Komatsu
Physics , 2002,
Abstract: We present theoretical and observational studies of non-Gaussian fluctuations in CMB, by using the angular bispectrum and trispectrum. We predict the primary angular bispectrum from inflation, and forecast how well we can measure the primordial non-Gaussian signal. In addition to that, secondary anisotropy sources in the low-redshift universe also produce non-Gaussianity, so do foreground emissions from extragalactic or interstellar microwave sources. We study how well we can measure these non-Gaussian signals, including the primordial signal. We find that slow-roll inflation produces too small bispectrum to be detected by any experiments; thus, any detection strongly constrains this class of models. We also find that the secondary bispectrum from coupling between the SZ effect and the weak lensing effect, and the foreground bispectrum from extragalactic point sources, give detectable non-Gaussian signals on small angular scales. We test Gaussianity of the COBE DMR sky maps, by measuring all the modes of the angular bispectrum down to the DMR beam size. We find no significant signal of the bispectrum. We also find that the previously reported detection of the bispectrum is consistent with a statistical fluctuation. By fitting the theoretical prediction to the data for the primary bispectrum, we put a constraint on non-linearity in inflation. We conclude that the angular bispectrum finds no significant non-Gaussian signals in the DMR data. We present the first measurement of the angular trispectrum on the DMR sky maps, further testing Gaussianity of the DMR data. We find no significant non-Gaussian signals in the trispectrum. Therefore, the angular bispectrum and trispectrum show that the DMR sky map is comfortably consistent with Gaussianity.
Periodicity Detection Method for Small-Sample Time Series Datasets
Daisuke Tominaga
Bioinformatics and Biology Insights , 2012, DOI: 10.4137/BBI.S5983
Abstract: Time series of gene expression often exhibit periodic behavior under the influence of multiple signal pathways, and are represented by a model that incorporates multiple harmonics and noise. Most of these data, which are observed using DNA microarrays, consist of few sampling points in time, but most periodicity detection methods require a relatively large number of sampling points. We have previously developed a detection algorithm based on the discrete Fourier transform and Akaike’s information criterion. Here we demonstrate the performance of the algorithm for small-sample time series data through a comparison with conventional and newly proposed periodicity detection methods based on a statistical analysis of the power of harmonics. We show that this method has higher sensitivity for data consisting of multiple harmonics, and is more robust against noise than other methods. Although “combinatorial explosion” occurs for large datasets, the computational time is not a problem for small-sample datasets. The MATLAB/GNU Octave script of the algorithm is available on the author’s web site: http://www.cbrc.jp/%7Etominaga/piccolo/.
Rings decomposed into direct sums of J-rings and nil rings
Hisao Tominaga
International Journal of Mathematics and Mathematical Sciences , 1985, DOI: 10.1155/s0161171285000230
Abstract: Let R be a ring (not necessarily with identity) and let E denote the set of idempotents of R. We prove that R is a direct sum of a J-ring (every element is a power of itself) and a nil ring if and only if R is strongly €-regular and E is contained in some J-ideal of R. As a direct consequence of this result, the main theorem of [1] follows.
Periodicity Detection Method for Small-Sample Time Series Datasets
Daisuke Tominaga
Bioinformatics and Biology Insights , 2010,
Urban and spatial planning in Japan
Marin Tominaga
Urbanism. Arhitectura. Constructii , 2011,
Abstract: This paper aims to introduce the urban and spatial planning inJapan. According to the national planning system of Japan, chapter 2, the planning system has 3 administrative levels and each territorial region has its own regulation. This paper introduces especially about planning and regulation system in city region in Japan.
The upper bound of a reserve H lder's type operator inequality and its applications
Tominaga Masaru
Journal of Inequalities and Applications , 2002,
Abstract: In our previous paper, we obtained a reverse H lder's type inequality which gives an upper bound of the difference: with a parameter , for -tuples and of positive numbers and for , satisfying . In this paper for commutative positive operators and on a Hilbert space and a unit vector , we give an upper bound of the difference As applications, considering special cases, we induce some difference and ratio operator inequalities. Finally, using the geometric mean in the Kubo-Ando theory we shall give a reverse H lder's type operator inequality for noncommutative operators.
Borehole Seismic and Strain Observatories in Seafloor Settings—Experiences after ODP Legs 186, 191, 195 and Future Plans
Eiichiro Araki,Kiyoshi Suyehiro
Scientific Drilling , 2007, DOI: 10.2204/iodp.sd.s01.13.2007
Cosmic Shears Should Not Be Measured In Conventional Ways
Jun Zhang,Eiichiro Komatsu
Physics , 2010, DOI: 10.1111/j.1365-2966.2011.18436.x
Abstract: A long standing problem in weak lensing is about how to construct cosmic shear estimators from galaxy images. Conventional methods average over a single quantity per galaxy to estimate each shear component. We show that any such shear estimators must reduce to a highly nonlinear form when the galaxy image is described by three parameters (pure ellipse), even in the absence of the point spread function (PSF). In the presence of the PSF, we argue that this class of shear estimators do not likely exist. Alternatively, we propose a new way of measuring the cosmic shear: instead of averaging over a single value from each galaxy, we average over two numbers, and then take the ratio to estimate the shear component. In particular, the two numbers correspond to the numerator and denominators which generate the quadrupole moments of the galaxy image in Fourier space, as proposed in Zhang (2008). This yields a statistically unbiased estimate of the shear component. Consequently, measurements of the n-point spatial correlations of the shear fields should also be modified: one needs to take the ratio of two correlation functions to get the desired, unbiased shear correlation.
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