oalib

Publish in OALib Journal

ISSN: 2333-9721

APC: Only $99

Submit

Any time

2020 ( 35 )

2019 ( 227 )

2018 ( 241 )

2017 ( 242 )

Custom range...

Search Results: 1 - 10 of 144398 matches for " Egid B. Mubofu "
All listed articles are free for downloading (OA Articles)
Page 1 /144398
Display every page Item
Fatty Acid Profile and Physico-Chemical Parameters of Castor Oils in Tanzania  [PDF]
Athumani Omari, Quintino A. Mgani, Egid B. Mubofu
Green and Sustainable Chemistry (GSC) , 2015, DOI: 10.4236/gsc.2015.54019
Abstract: This paper reports on the assessment of the quality and quantity of castor oil from castor seeds collected from different regions in Tanzania. The castor seeds from Arusha, Dar es Salaam, Dodoma, Iringa, Kagera and Morogoro regions in Tanzania were extracted by Soxhlet method using n-hexane and the oil yields were determined. The yields were 52.78%, 49.95%, 47.89%, 44.23%, 43.71% and 43.69% for Dodoma, Arusha, Iringa, Morogoro, Kagera and Dar es Salaam respectively. The physico-chemical parameters that were determined were refractive index (1.468 - 1.473), pH 5.7- 6.3, viscosity (0.943 - 0.954), specific gravity (165.50 - 187.46 mg KOH/g Oil), saponification value (76.68 - 80 mg KOH/g Oil), iodine value (76.68 - 80.12 g I2/100 g Oil), acid value (0.44 - 1.97 mg NaOH/g Oil), free fatty acid (0.22 - 0.99) and peroxide value (10.79 - 13.73). Fatty acid profile of castor oil was analysed using Shimadzu GCMS and ricinoleic acid ranged from 83.5% to 92.3% of the total fatty acids in the castor oils.
In Silico Evaluation of Anti-Malarial Agents from Hoslundia opposita as Inhibitors of Plasmodium falciparum Lactate Dehydrogenase (PfLDH) Enzyme  [PDF]
Daniel M. Shadrack, Stephen S. Nyandoro, Joan J. E. Munissi, Egid B. Mubofu
Computational Molecular Bioscience (CMB) , 2016, DOI: 10.4236/cmb.2016.62002
Abstract: Malaria has continued to be a health and economic problem in Africa and the world at large. Many anti-malarial drugs have been rendered ineffective due to the emergence of resistant strains of Plamodium falciparum. A key malaria parasite enzyme in glycolytic pathway, P. falciparum lactate dehydrogenase (PfLDH) is specially targeted for anti-malarial drugs development. Thus, the aim of this investigation was to determine the in silico inhibition effects of antimalarial compounds from Hoslundia opposita Vahl. namely hoslundin, hoslundal and hoslunddiol on PfLDH enzyme. The compounds were docked to the three-dimensional structure of PfLDH as enzyme using AutoDock Vina in PyRx virtual screening software. Binding affinity and position of the inhibitors were evaluated using PyMol software. The PfLDH enzyme showed two binding sites: the cofactors binding site (Site A) and secondary binding site (Site B). In the absence of the cofactor all ligands showed higher affinity than NADH, and were bound to the cofactors binding site (Site A). When docked in the presence of the cofactor, site B was the preferred binding site. Binding to cofactor site with higher binding energy than NADH suggests that these ligands could act as preferential competitive inhibitors of PfLDH. However, the binding to site B also suggests that they may be non-competitive allosteric inhibitors. Amino acid residues Gly99, Asn140, Phe100 and Thr97 were indicated to form hydrogen bonds with Hoslundin. Hoslunddiol showed hydrogen bonding with Thr97 and Met30, while Hoslundal formed hydrogen bond with Thr101 and Asn140.
Meticulous Overview on the Controlled Release Fertilizers
Siafu Ibahati Sempeho,Hee Taik Kim,Egid Mubofu,Askwar Hilonga
Advances in Chemistry , 2014, DOI: 10.1155/2014/363071
Abstract: Owing to the high demand for fertilizer formulations that will exhaust the possibilities of nutrient use efficiency (NUE), regulate fertilizer consumption, and lessen agrophysicochemical properties and environmental adverse effects instigated by conventional nutrient supply to crops, this review recapitulates controlled release fertilizers (CRFs) as a cutting-edge and safe way to supply crops’ nutrients over the conventional ways. Essentially, CRFs entail fertilizer particles intercalated within excipients aiming at reducing the frequency of fertilizer application thereby abating potential adverse effects linked with conventional fertilizer use. Application of nanotechnology and materials engineering in agriculture particularly in the design of CRFs, the distinctions and classification of CRFs, and the economical, agronomical, and environmental aspects of CRFs has been revised putting into account the development and synthesis of CRFs, laboratory CRFs syntheses and testing, and both linear and sigmoid release features of CRF formulations. Methodical account on the mechanism of nutrient release centring on the empirical and mechanistic approaches of predicting nutrient release is given in view of selected mathematical models. Compositions and laboratory preparations of CRFs basing on in situ and graft polymerization are provided alongside the physical methods used in CRFs encapsulation, with an emphasis on the natural polymers, modified clays, and superabsorbent nanocomposite excipients. 1. Introduction Controlled release fertilizers (CRFs) are fertilizer granules intercalated within carrier molecules commonly known as excipients to control nutrients release thereby improving nutrient supply to crops and minimize environmental, ecological, and health hazards [1]. In that sense, CRFs usage is an advanced way to supply crop’s nutrients (cf. conventional ways) due to gradual pattern of nutrient release, which improves fertilizer use efficiency (FUE) [2]. In other words, depending on the thickness of the coatings within the formulation, CRFs enable nutrients to be released over an extended period leading to an increased control over the rate and pattern of release [3], consequently the excipients play a role in regulating nutrients release time and eliminate the need for constant fertilization and higher efficiency rate than conventional soluble fertilizers [1]. Occasionally the terms controlled release fertilizers (CRFs) and slow release fertilizers (SRFs) have been used interchangeably, yet they are different. Typically, the endorsed differences between
Post harvest changes in physico-chemical properties and levels of some inorganic elements in off vine ripened orange (Citrus sinensis) fruits cv (Navel and Valencia) of Tanzania
GP Mbogo, EB Mubofu, CC Othman
African Journal of Biotechnology , 2010,
Abstract: Two orange (Citrus sinensis) fruit varieties, Navel and Valencia, from Muheza in Tanga, were analyzed for their proximate composition (ash, acidity, crude fat, crude fibre, sugars and moisture content), ascorbic acid, sugars, concentrations of four macro elements (Ca, Mg, K, Na) and seven heavy metals (Al, Cd, Cu, Fe, Mn, Pb, Zn). The oranges had high moisture content (>68%), moderate titratable acidity (0.60 – 1.65% c.a.), low crude fat content (0.60 – 0.66 g/100 g-fresh weight (fw)), low crude fibre amounts (0.63 – 0.75 g/100 g-fw), low ash content (0.68 – 0.72 g/100 g-fw), high reducing sugars (6.6 – 13.1%), high total sugars (11.4 – 33.4%), high total soluble solids (11.5 – 31.8%) and high ascorbic acid (22.5 – 50.4%). Very low concentrations of the seven heavy metals were detected in the fruits. Ascorbic acid, moisture, titratable acidity, sugars content varied within the season and with storage-ripening time. The high moisture content suggests the usefulness of these fruits in the treatment of obesity. The citric acid which these fruits contain makes them to be used as acid foods when required. The value of ascorbic acid which is above 30 mg/day in these fruits allows them to be considered as good sources of ascorbic acid for human nutrition.
Hospital use of systemic antifungal drugs
Katja de With, Michaela Steib-Bauert, Holger Knoth, Frank D?rje, Egid Strehl, Ulrich Rothe, Ludwig Maier, Winfried V Kern
BMC Pharmacology and Toxicology , 2005, DOI: 10.1186/1472-6904-5-1
Abstract: Hospital pharmacy records for the years 2001 to 2003 were evaluated, and the number of prescribed daily doses (PDD, defined according to locally used doses) per 100 patient days were calculated to compare systemic antifungal drug use density in different medical and surgical service areas between five state university hospitals.The 3-year averages in recent antifungal drug use for the five hospitals ranged between 8.6 and 29.3 PDD/100 patient days in the medical services (including subspecialties and intensive care), and between 1.1 and 4.0 PDD/100 patient days in the surgical services, respectively. In all five hospitals, systemic antifungal drug use was higher in the hematology-oncology service areas (mean, 48.4, range, 24 to 101 PDD/100 patient days, data for the year 2003) than in the medical intensive care units (mean, 18.3, range, 10 to 33 PDD/100) or in the surgical intensive care units (mean, 10.7, range, 6 to 18 PDD/100). Fluconazole was the most prescribed antifungal drug in all areas. In 2003, amphotericin B consumption had declined to 3 PDD/100 in the hematology-oncology areas while voriconazole use had increased to 10 PDD/100 in 2003.Hematology-oncology services are intense antifungal drug prescribing areas. Fluconazole and other azol antifungal drugs are the most prescribed drugs in all patient care areas while amphotericin B use has considerably decreased. The data may be useful as a benchmark for focused interventions to improve prescribing quality.There has been a major increase in the prescription of antifungal drugs after the introduction of fluconazole into the market in the late 1980s, and again in the late 1990s. The systemic antifungal market has continued to experience growth since 1999, increasing in value from $2.1 billion to $3.3 billion in 2003. The azoles dominate the systemic antifungal market, accounting for 52% of total sales in 2003 [1-8]. The reasons for the increasing antifungal drug use are manifold. Among hospitalized patients, t
The Mélange of Innovation and Tradition in Maltese Law: The Essence of the Maltese Mix?
B Andò
Potchefstroom Electronic Law Journal/Potchefstroomse Elektroniese Regsblad , 2012,
Abstract: Aim of this paper is to provide valuable insights into the Maltese legal system with a special focus on private law. The assumption is that this legal system is the byproduct of the "mixing" of innovation and tradition, resulting from the interaction of English law and continental law. A major role in the development of the system is played by courts. Some examples (moral damages and pre-contractual liability) are considered which highlight the importance of the function displayed by Maltese judges. KEYWORDS: Tradition; English law; continental law; hybridity; mixed legal systems; Maltese courts; moral damages; pre-contractual liability; lacunae
PROBLEMS OF FLIGHT PERSONNEL PREPARATION FOR MODERN AIRCRAFTS П ДГОТОВКА ЛЬОТНОГО СКЛАДУ НА СУЧАСН ПОВ ТРЯН СУДНА П ДГОТОВКА ЛЬОТНОГО СКЛАДУ НА СУЧАСН ПОВ ТРЯН СУДНА
B. Харченко,О. Ал?кс??в,Д. Бабейчук,М. Повознюк
Proceedings of National Aviation University , 2011,
Abstract: At present, the problem who can and who should solve the question concerning the preparationand recurrent training of pilots of Ukrainian civil aviation is not solved. The necessity of updatingof aircraft’s park in aviation branch and aircraft operation, which was ripened 10 years ago,demands a corresponding infrastructure. It is necessary to understand, that the pilots ready toperform the flights on modern aircrafts, will not appear by themselves, therefore the real actions onmodernization of existing system of aircrew and the aviation personnel preparation as a whole arerequired. Main objective of this work is the determination of the basic components concerning thesolving of the problematic questions on preparation of aircrew on modern types of aircrafts. Duringthe problem analysis it was specified that the present development of system of aircrew preparationin Ukraine is not perfect, and does not correspond the ICAO and EU requirements, therefore needsan immediate intervention at the highest State level. Trainings are not complex, as do not containthe elements of selection of aircrew members cooperation. Programs of recurrent training ofaircrew, courses of pilots training flight preparation were not reconsidered for many years Розглянуто проблему п дготовки п лот в цив льно ав ац Уккра ни, яка на сьогодн нев дпов да вимогам ICAO та С. Визначено основн складов п дготовки льотного складу насучасн пов трян судна.Ключов слова: аеронав гац йне обслуговування, керована множина, керован об’ кти,рад олокац йне та рад онав гац йне забезпечення польот в, системи керування пов трянимрухом. Розглянуто проблему п дготовки п лот в цив льно ав ац Уккра ни, яка на сьогодн нев дпов да вимогам ICAO та С. Визначено основн складов п дготовки льотного складу насучасн пов трян судна.
METHOD OF SYNTHESIS OF PROBLEM QUALITY OF THE COMPLEX NONLINEAR DYNAMIC SYSTEM CONTROL МЕТОД ГАРАНТОВАНОГО ОЦ НЮВАННЯ ОБЛАСТ ПОВН СТЮКЕРОВАНОГО СТАНУ СКЛАДНО НЕЛ Н ЙНО ДИНАМ ЧНО СИСТЕМИ МЕТОД ГАРАНТОВАНОГО ОЦ НЮВАННЯ ОБЛАСТ ПОВН СТЮ КЕРОВАНОГО СТАНУ СКЛАДНО НЕЛ Н ЙНО ДИНАМ ЧНО СИСТЕМИ
С. Павлова,B. Павлов,В. Чеп?женко
Proceedings of National Aviation University , 2011,
Abstract: Substantially nonlinear objects function at limitations of arbitrary kind. These limitations are not necessarily convex areas. For such objects the construction of area of the fully the fully-controlled state area is a serious problem. In the article it has been suggested to replace this task the task of the fully-controlled state area estimation from within. The secure estimation method of the fully-controlled state area has been developed for this purpose. Other dynamic system has been used as a tester (measure) of the fully-controlled state area. Construction and estimation of controllability and accessibility area of this dynamic system well methodically validate and deserved researchers confession. The descriptions concordance requirements of this new object with properties of initial object must be executed and provide property of immersion of new object in an initial object. Possibility is thus opened on the the fully-controlled state area of new object to define the the fully-controlled state area of the initial system На основ процедури мерсування м рних об’ кт в у вих дний об’ кт розроблено методгарантованого оц нювання област повн стю керованого стану.On the basis of procedure of immersion of the measuring objects in an initial object the secureestimation method of the fully controlled state area has been developed.На основе процедуры иммерсирования мерных объектов в исходный объект разработанметод гарантированного оценивания области полностью управляемого состояния. Показано, що для стотно нел н йних об’ кт в, що функц онують в умовах наявност обме-жень дов льного виду, як не обов’язково опуклими областями, побудова област повн стюкерованого стану проблематична. Запропоновано зам нити це завдання оц нюванням област повн стю керованого стану зсередини. Для цього розроблено метод гарантовано оц нюванняобласт повн стю керованого стану. Як вим рника (м ра) област повн стю керованого станувикористана нша динам чна система, п
THE SYSTEM METHOD OF IMMERSION AND VIRTUALIZATION OF MEASURED SYSTEMS IN REAL PROCESS СИСТЕМНИЙ МЕТОД МЕРСУВАННЯ ТА В РТУАЛ ЗАЦ М РНИХ СИСТЕМ У РЕАЛЬНИЙ ПРОЦЕС СИСТЕМНИЙ МЕТОД МЕРСУВАННЯ ТА В РТУАЛ ЗАЦ М РНИХ СИСТЕМ У РЕАЛЬНИЙ ПРОЦЕС
С. Павлова,B. Павлов,В. Чеп?женко
Proceedings of National Aviation University , 2012,
Abstract: The system method of immersion and virtualization of measured systems in real process is offered. The method works out problem of virtual systems formation and sets conditions at which virtual object to become measuring system for of completely controlled condition field. Here the system of interactively oriented rectangular n-dimensional parallelepipeds is used as measuring system. Imbeddedness of measuring system in real process is understood as process of approximation of a real system controlled condition cone by system of rectangular n-dimensional parallelepipeds. Запропоновано системний метод мерсування та в ртуал зац м рних систем вреальний динам чний процес як процедуру утворення вкладених в ртуальних систем,визначених на погоджено-ор нтованих прямокутних п-вим рних паралелеп педах.Ключов слова: в ртуал зац я, в ртуальний м рний процес, мерс я, складна нел н йнадинам чна система. Запропоновано системний метод мерсування та в ртуал зац м рних систем в реальний динам чний процес як процедуру утворення вкладених в ртуальних систем, визначених на погоджено-ор нтованих прямокутних п-вим рних паралелеп педах.
THE MéLANGE OF INNOVATION AND TRADITION IN MALTESE LAW: THE ESSENCE OF THE MALTESE MIX?
B Andò
Potchefstroom Electronic Law Journal/Potchefstroomse Elektroniese Regsblad , 2012,
Abstract: Aim of this paper is to provide valuable insights into the Maltese legal system with a special focus on private law. The assumption is that this legal system is the by-product of the "mixing" of innovation and tradition, resulting from the interaction of English law and continental law. A major role in the development of the system is played by courts. Some examples (moral damages and pre-contractual liability) are considered which highlight the importance of the function displayed by Maltese judges.
Page 1 /144398
Display every page Item


Home
Copyright © 2008-2017 Open Access Library. All rights reserved.