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Search Results: 1 - 10 of 2879 matches for " Edson;Mazer "
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Al?a da artéria pulmonar: relato de dois casos e revis?o da literatura
Santana, Pablo Rydz Pinheiro;Irion, Klaus Loureiro;Escuissato, Dante Luiz;Porto, Nelson da Silva;Fisher, Gilberto Bueno;Mocelin, Helena Terezinha;Marchiori, Edson;Mazer, Sérgio;
Radiologia Brasileira , 2005, DOI: 10.1590/S0100-39842005000400014
Abstract: the authors report two cases of pulmonary artery sling diagnosed by three-dimensional reconstruction of images of the tracheobronchial tree and the esophagus acquired using magnetic resonance imaging or helical computer tomography. the typical clinical findings of this congenital abnormality, which may not be as rare as previously believed, include those related to severe tracheobronchial obstruction, although asymptomatic or mild symptomatic cases have been reported. early diagnosis of this anomaly is extremely important, since in most cases immediate surgical correction is indicated due to its high lethality. the use of three-dimensional reconstruction allows simultaneous identification of the associated tracheobronchial and cardiovascular malformations, in addition to a clear visualization of the anomaly. thus, the diagnosis can usually be established non-invasively, avoiding the use of the selective angiocardiography, considered the gold-standard.
Hologram devouration: reflections from mediagenic spaces revisited by Norval Baitello Junior A devora o do holograma: reflex es sobre os espa os midiáticos revisitados por Norval Baitello Junior
Alberto Klein,Dulce Mazer
Discursos Fotográficos , 2011,
Abstract: Resenha do livro BAITELLO JúNIOR, Norval. A serpente, a ma e o holograma: esbo os para uma teoria da mídia. S o Paulo: Paulus, 2010. 120p.
IL-13 GENE TRANSLATION IS ARRESTED BY A NOVEL OLIGONUCLEOTIDE IN CULTURED HUMAN B- LYMPHOCYTES
Tahere Mousavi,Bruce Mazer
Iranian Journal Of Allergy, Asthma and Immunology , 2003,
Abstract: Antisense oligodeoxynucleotides (oligos) are the tools that bind to complemen tary sequence of targeted mRNA and block specifically protein translation. In the present study, a novel 20 mer oligo as an antisense for human IL-13 is introduced. This oligo is designed according to the IL-13 mRNA coding region and synthesized in two HPLC purified and FITC conjugated forms. Fluorescence oligo cell uptake is confirmed using flowcytometry and confocal microscopy, and cytotoxicity evaluation is performed us ing BrdU proliferation assay. Human tonsilar B-lymphocytes are purified by positive selection using magnetic cell sorting method and cultured with anti CD40 monoclonal antibody plus rIL-4 to induce IL-13 production. IL-13 antisense is added to medium and Real Time PCR for mRNA, and ELISA for protein assays. Data indicate that antisense application leads to down regulation and complete suppression of IL-13 pro tein with no significant effects on mRNA, suggesting in vitro protein translation arrest. Since 11-13 is a crucial cytokine in allergic conditions, we conclude that interference with the protein synthesis by a nontoxic and efficient antisense oligo can provide an available tool for the investigators on allergic diseases.
Recurrent Pregnancy Loss in Patients with Polycystic Ovary Syndrome: A Case Control Study  [PDF]
Lulwa Ashaq, Yousef Al Mazer, Nourah Al Qahtani
Open Journal of Obstetrics and Gynecology (OJOG) , 2017, DOI: 10.4236/ojog.2017.711108
Abstract: Objectives: To identify different biophysical and hormonal factors that could contribute to recurrent pregnancy loss in Saudi women who have been diagnosed with polycystic ovary syndrome. Study Design: Case-control study. Settings: Infertility clinic in Dammam Maternity and Children Hospital. Cases: PCOS patients with recurrent pregnancy loss. Controls: PCOS patients without recurrent pregnancy loss. Results: The prevalence of recurrent abortion in PCOS patients was 31%. There was no significant difference between the cases and the controls in the age, 33.1 years versus 31.9 years, BMI, 31.4 kg/m2 versus 31.6 kg/m2 respectively. There was no significant difference in the successful pregnancies outcome in cases and controls, term deliveries 84% versus 90%, preterm deliveries 10% versus 5%, twin pregnancy 6% versus 5% respectively. There was no significant difference in the hormonal profile (prolactin, LH, FSH, LH/FSH ratio, TSH, progesterone, testosterone) between cases and controls. Serum estradiol level was significantly lower in the cases compared to the controls, 55.5 pg/mL versus 83.9 pg/mL respectively (p < 0.01). Conclusion: PCOS patients with recurrent abortions had no significant increase in the age, BMI, preterm pregnancy, multiple gestation and ectopic pregnancy. The hormonal profile (prolactin, LH, FSH, LH/FSH ratio, TSH, progesterone, testosterone) was comparable between the cases and the controls, except for serum estradiol level, which was significantly lower in PCOS patients with recurrent abortions.
Population Dynamics of Large Herbivores and the Framing of Wildlife Conservation in Zimbabwe  [PDF]
Edson Gandiwa
Open Journal of Ecology (OJE) , 2014, DOI: 10.4236/oje.2014.47036
Abstract:

This article reviews: 1) The role of natural and human-induced controls in influencing large herbivore populations; 2) how human controls (i.e., policy instruments, incentives and provisions) influence human activities and wildlife conservation; and 3) media framing of wildlife conservation using Zimbabwe as a case study, in particular Gonarezhou National Park and adjacent areas. The review shows that droughts are important in influencing large herbivore populations in semi-arid ecosystems; political instability and economic collapse does not necessarily lead to increased illegal hunting in situations where policy instruments, such as laws, are enforced. A higher perceived effectiveness of Communal Areas Management Programme for Indigenous Resources was partly associated with a decline in human-wildlife conflicts and there was a spill-over effect of frames from the political domain into wildlife conservation following Zimbabwe’s land reforms in 2000. It is concluded that natural bottom-up processes (e.g., droughts) influence large herbivore population dynamics whereas policy instruments, incentives, provisions and societal frames mainly have a top-down effect on wild large herbivore populations in savanna ecosystems.

A survey of poison control centers worldwide
Ali Pourmand, Justin Wang, Maryann Mazer
DARU Journal of Pharmaceutical Sciences , 2012, DOI: 10.1186/2008-2231-20-13
Abstract: Poisonings are a major cause of morbidity and mortality worldwide and as such represent a major public health threat, especially to children, according to a World Health Organization (WHO) report [1]. Potentially toxic exposures can be pharmaceutical, chemical, occupational, or environmental in nature. Technological progress has hastened the rate at which novel chemicals are developed and made available to the public, further raising the potential for adverse effects and outcomes. Our ability to detect chemicals in the body and the environment has increased substantially over the past two decades; however, there is still a paucity of toxicology data due to a lack of controlled data. According to the Centers for Disease Control and Prevention, deaths due to poisoning surpassed deaths related to motor vehicle accidents in the United States in 2008, and this trend appears to be continuing [2].To stem the rising incidence of toxic exposure as well as the associated morbidity and mortality, the past century has seen the establishment and evolution of poison control centers (PCCs) worldwide. Depending on the location, PCCs vary in terms of staffing model, services offered, and funding sources. Numerous studies have demonstrated the cost-effectiveness of PCCs in terms of number of emergency department visits avoided and decreased hospital length of stay [3-5]. In fact, an assessment by the Institute of Medicine attributes $10 of potential healthcare spending avoided for every $1 spent on funding PCCs [6]. Additionally, the utilization of PCCs has been associated with improved patient outcomes [3-5].In the United States, the American Association of Poison Control Centers (AAPCC) oversees the nation’s 57 PCCs by providing accreditation as well as staff certification and continuing education. Healthcare professionals and the general public alike may solicit advice free of charge from PCCs 24 hours a day, 365?days a year, through a national telephone hotline [7]. PCC staff typ
Perceived ideological bias in the college classroom and the role of student reflective thinking: A proposed model
Darren L. Linvill,Joseph P. Mazer
The Journal of Scholarship of Teaching and Learning , 2011,
Abstract:
Pollen Performance in Clarkia Taxa with Contrasting Mating Systems: Implications for Male Gametophytic Evolution in Selfers and Outcrossers
Alisa A. Hove,Susan J. Mazer
Plants , 2013, DOI: 10.3390/plants2020248
Abstract: We tested three predictions regarding the joint evolution of pollen performance and mating system. First, due to the potential for intense intrasexual competition in outcrossing populations, we predicted that outcrossers would produce faster-growing pollen than their selfing relatives. Second, if elevated competition promotes stronger selection on traits that improve pollen performance, then, among-plant variation in pollen performance would be lower in outcrossers than in selfers. Third, given successive generations of adaptation to the same maternal genotype in selfers, we predicted that, in selfing populations (but not in outcrossing ones), pollen would perform better following self- than cross-pollinations. We tested these predictions in field populations of two pairs of Clarkia (Onagraceae) sister taxa. Consistent with our predictions, one outcrosser ( C. unguiculata) exhibited faster pollen germination and less variation in pollen tube growth rate (PTGR) among pollen donors than its selfing sister species, C. exilis. Contrary to our predictions, the selfing C. xantiana ssp. parviflora exhibited faster PTGR than the outcrossing ssp. xantiana, and these taxa showed similar levels of variation in this trait. Pollen performance following self- vs. cross-pollinations did not differ within either selfing or outcrossing taxa. While these findings suggest that mating system and pollen performance may jointly evolve in Clarkia, other factors clearly contribute to pollen performance in natural populations.
The Ariadne's Clew Algorithm
J. M. Ahuactzin,P. Bessiere,E. Mazer
Computer Science , 2011, DOI: 10.1613/jair.468
Abstract: We present a new approach to path planning, called the "Ariadne's clew algorithm". It is designed to find paths in high-dimensional continuous spaces and applies to robots with many degrees of freedom in static, as well as dynamic environments - ones where obstacles may move. The Ariadne's clew algorithm comprises two sub-algorithms, called Search and Explore, applied in an interleaved manner. Explore builds a representation of the accessible space while Search looks for the target. Both are posed as optimization problems. We describe a real implementation of the algorithm to plan paths for a six degrees of freedom arm in a dynamic environment where another six degrees of freedom arm is used as a moving obstacle. Experimental results show that a path is found in about one second without any pre-processing.
Platelet-Activating Factor Antagonists Decrease Follicular Dendritic-Cell Stimulation of Human B Lymphocytes
Isaac Halickman, Yolande Bastien, Qianli Zhuang, Monty B Mazer, Baruch Toledano, Bruce D Mazer
Allergy, Asthma & Clinical Immunology , 2005, DOI: 10.1186/1710-1492-1-2-49
Abstract: Antigen presentation is a crucial part of any immune response. Antigen-presenting cells coordinate the interaction between antigens and effector cells such as Tlymphocytes and B lymphocytes. Follicular dendritic cells (FDCs) are specific antigen-presenting cells that interact with B lymphocytes. These cells, found in lymph node germinal centres (GCs), trap antigens in immune complexes and present them to surface immunoglobulin receptors on B lymphocytes. This leads to the interaction of B lymphocytes with antigens and is a crucial step in the generation of long-lasting antibody responses and memory B lymphocytes [1]. However, FDCs provide additional signals via adhesion receptors and through a network of channels that rescue B lymphocytes from apoptosis, allowing them to proliferate and ultimately secrete immunoglobulin. These points of attachment include adhesion molecules such as VLA-4, the complement receptor CR2, and other molecules potentially [2]. There are also multiple tight conjunction links between the B lymphocytes and the FDCs, and it is presumed that molecules such as soluble mediators or lipids pass through these tight junctions and enhance the communication between B lymphocytes and the FDCs [3].The lineage of FDCs is unclear. They may arise from bone marrow stem cells similar to those that interact with B lymphocytes in their early development. However, a second possible lineage is monocyte or macrophage lineage, similar to the lineage of dendritic cells that interact with T lymphocytes [4]. This confusion persists because FDCs have both features of stromal cells and features of monocytes such as CD14 and adhesion molecules such as VLA-4 [5,6].We have determined that platelet-activating factor (PAF), a potent lipid mediator, can abrogate apoptosis and elevate immunoglobulin levels in B-lymphoblastoid cell lines [7,8]. More recently, we demonstrated that GC-like B lymphocytes isolated from tonsils had a high level of PAF receptor (PAFR) messenger ribo
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