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Search Results: 1 - 10 of 1057 matches for " Edna;GAYOTTO "
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Size of gastroesophageal varices: its behavior after the surgical treatment of portal hypertension
Strauss, Edna;Sakai, Paulo;Gayotto, Luiz Carlos da Costa;Cardoso, Rita Antonelli;Forster, Sonia;Raia, Silvano;
Revista do Hospital das Clínicas , 1999, DOI: 10.1590/S0041-87811999000600005
Abstract: the size of gastroesophageal varices is one of the most important factors leading to hemorrhage related to portal hypertension. an endoscopic evaluation of the size of gastroesophageal varices before and after different operations for portal hypertension was performed in 73 patients with schistosomiasis, as part of a randomized trial: proximal splenorenal shunt (pss n=24), distal splenorenal shunt (dss n=24), and esophagogastric devascularization with splenectomy (egds n=25). the endoscopic evaluation was performed before and up to 10 years after the operations. variceal size was graded according to palmer's classification: grade 1 ? up to 3 mm, grade 2 ? from 3 to 6 mm, grade 3 ? greater than 6 mm, and were analyzed in four anatomical locations: inferior, middle or superior third of the esophagus, and proximal stomach. the total number of points in the pre-operative grading minus the number of points in the post-operative grading gave a differential grading, allowing statistical comparison among the surgical groups. good results, in terms of disappearance or decrease of variceal size, were observed more frequently after pss than after dss or egds - 95.8%, 83.3%, and 72%, respectively. when differential grading was analyzed, a statistically significant difference was observed between pss and egds, but not between proximal and distal splenorenal shunts. in conclusion, shunt surgeries were more efficient than devascularization in diminishing variceal size.
An ELISA method using serum derived HDAg for the sorological detection of HDV antigens and antibodies
Granato, Celso;Strauss, Edna;Vitvitsky, Ludmila;Gayotto, Luiz Carlos da Costa;Trepo, Christian;
Revista do Instituto de Medicina Tropical de S?o Paulo , 1987, DOI: 10.1590/S0036-46651987000600010
Abstract: one of the main difficulties related to the detection of the hepatitis delta virus (hdv) antigen and antibody has been the source of the needed hd antigen since hdv containing human and animal livers are very difficult to obtain and since yield is low. this fact prompted us to try to use the serum of patients in the acute phase of hdv infection as a source of hdag and turn to enzyme immunoassays (eia) instead of ria for the sake of easiness and economy in the amount of hdag needed. the antigen for eia was obtained from patients during the acute phase of hdv infection and the antibody from patients who have been carriers for many years. for the detection of the antigen, a sandwich type method was employed, whereas for the antibody a competition assay was developed. in order to assess the relative specificity and sensibility of the test, the antibody assay was compared to a commercial ria (c. ria, abbott) and to a non-commercial ria (nc ria). forty-two sera were tested by the two methods and only in two cases discrepant results were obtained. its is concluded that: 1) sera from patients in the acute and chronic phases of hdv infection can be used as source of both antigen and antibody, for immunoassays; 2) eia and ria have comparable relative specificity and sensibility and 3) eia is easier to perform, cheaper, non-hazardous, has a longer shelf-life and saves scarce hdag.
Size of gastroesophageal varices: its behavior after the surgical treatment of portal hypertension
Strauss Edna,Sakai Paulo,Gayotto Luiz Carlos da Costa,Cardoso Rita Antonelli
Revista do Hospital das Clínicas , 1999,
Abstract: The size of gastroesophageal varices is one of the most important factors leading to hemorrhage related to portal hypertension. An endoscopic evaluation of the size of gastroesophageal varices before and after different operations for portal hypertension was performed in 73 patients with schistosomiasis, as part of a randomized trial: proximal splenorenal shunt (PSS n=24), distal splenorenal shunt (DSS n=24), and esophagogastric devascularization with splenectomy (EGDS n=25). The endoscopic evaluation was performed before and up to 10 years after the operations. Variceal size was graded according to Palmer's classification: grade 1 -- up to 3 mm, grade 2 -- from 3 to 6 mm, grade 3 -- greater than 6 mm, and were analyzed in four anatomical locations: inferior, middle or superior third of the esophagus, and proximal stomach. The total number of points in the pre-operative grading minus the number of points in the post-operative grading gave a differential grading, allowing statistical comparison among the surgical groups. Good results, in terms of disappearance or decrease of variceal size, were observed more frequently after PSS than after DSS or EGDS - 95.8%, 83.3%, and 72%, respectively. When differential grading was analyzed, a statistically significant difference was observed between PSS and EGDS, but not between proximal and distal splenorenal shunts. In conclusion, shunt surgeries were more efficient than devascularization in diminishing variceal size.
Liver histology in co-infection of hepatitis C virus (HCV) and Hepatitis G virus (HGV)
STRAUSS Edna,GAYOTTO Luiz Carlos da Costa,FAY Fabian,FAY Oscar
Revista do Instituto de Medicina Tropical de S?o Paulo , 2002,
Abstract: As little is known about liver histology in the co-infection of hepatitis C virus (HCV) and hepatitis G virus (HGV), HGV RNA was investigated in 46 blood donors with hepatitis C, 22 of them with liver biopsy: co-infection HCV / HGV (n = 6) and HCV isolated infection (n = 16). Besides staging and grading of inflammation at portal, peri-portal and lobular areas (Brazilian Consensus), the fibrosis progression index was also calculated. All patients had no symptoms or signs of liver disease and prevalence of HGV / HCV co-infection was 15.2%. Most patients had mild liver disease and fibrosis progression index, calculated only in patients with known duration of infection, was 0.110 for co-infection and 0.130 for isolated HCV infection, characterizing these patients as "slow fibrosers". No statistical differences could be found between the groups, although a lesser degree of inflammation was always present in co-infection. In conclusion co-infection HCV / HGV does not induce a more aggressive liver disease, supporting the hypothesis that HGV is not pathogenic.
Liver histology in co-infection of hepatitis C virus (HCV) and Hepatitis G virus (HGV)
STRAUSS, Edna;GAYOTTO, Luiz Carlos da Costa;FAY, Fabian;FAY, Oscar;FERNANDES, Helena Sabino;CHAMONE, Dalton de Alencar Fischer;
Revista do Instituto de Medicina Tropical de S?o Paulo , 2002, DOI: 10.1590/S0036-46652002000200003
Abstract: as little is known about liver histology in the co-infection of hepatitis c virus (hcv) and hepatitis g virus (hgv), hgv rna was investigated in 46 blood donors with hepatitis c, 22 of them with liver biopsy: co-infection hcv / hgv (n = 6) and hcv isolated infection (n = 16). besides staging and grading of inflammation at portal, peri-portal and lobular areas (brazilian consensus), the fibrosis progression index was also calculated. all patients had no symptoms or signs of liver disease and prevalence of hgv / hcv co-infection was 15.2%. most patients had mild liver disease and fibrosis progression index, calculated only in patients with known duration of infection, was 0.110 for co-infection and 0.130 for isolated hcv infection, characterizing these patients as "slow fibrosers". no statistical differences could be found between the groups, although a lesser degree of inflammation was always present in co-infection. in conclusion co-infection hcv / hgv does not induce a more aggressive liver disease, supporting the hypothesis that hgv is not pathogenic.
Expans?o da fronteira, megaprojetos de infraestrutura e integra??o sul-americana
Castro, Edna;
Caderno CRH , 2012, DOI: 10.1590/S0103-49792012000100004
Abstract: the analysis of the relationship between developmentalist policies and social and territorial dynamics in the amazon usually focuses on a brazilian national perspective. this article aims to reveal an increase of interest in the exploitation of the region's natural resources, beyond its political borders, thus turning the pan-amazon into a vital zone in brazilian geopolitics. the brazilian growth acceleration programs (pac i and ii) and the initiative for the integration of the regional infrastructure of south america (iirsa) follow the same direction of a competitive integration, adopting a modernization model based on investment megaprojects. the iirsa, carried on in south america as a regional block, and the pac, developed nationwide, are programs that aim to boost transport, energy and communication logistics. continent-wise, they both indicate irreversible social and territorial dynamics and represent the common interests of brazil and the other countries, based on the 1970's dominant model of border expansion in the amazon.
Hepatite C
Strauss, Edna;
Revista da Sociedade Brasileira de Medicina Tropical , 2001, DOI: 10.1590/S0037-86822001000100011
Abstract: it has been estimated that 3% of the world population is infected with the hepatitis c virus. those who are blood product recipients or have been illicit drug users are at risk. dental and medical procedures as well as tattooing and acupuncture are also risk factors. chronic infection occurs in up to 85% of infected cases but they may remain without symptoms during years or even decades, and clinical presentation varies. determination of anti-hcv in sera is a fairly sensitive tool for the diagnosis, and confirmation requires the identification of hcv-rna. staging of the liver disease as well as definition of its present activity can be graded by liver biopsy. the aim of treatment is to stop the progression of the hepatic disease by inhibiting viral replication. due to the low therapeutic efficacy combined with important side-effects, the administration of interferon and ribavirin have specific indications and contraindications. predictive factors of therapeutic response, particularly viral load and genotypes of hcv, are useful in the evaluation of patients.
Sylvia Ostrowetsky em visita a Belém
Edna Castro
Sociedade e Estado , 2004, DOI: 10.1590/s0102-69922004000200014
Abstract:
Representations of journalism on public broadcasting: the debate on the creation of Empresa Brasil de Comunica o in the press
MIOLA, Edna
Revista Compolítica , 2011,
Abstract: This paper analyzes how the press covered the process of creation of the Empresa Brasil de Comunica o (EBC) - a public broadcaster proposed and managed by the Brazilian Government. The empirical sample considers a set of pieces published in the Folha de S. Paulo (the main Brazilian newspaper) while the Congress was voting the bill. As the main conclusions, it is possible to point out that (1) the coverage emphasized the decision-making process itself, and not the substance of the bill (its implications, for example); (2) the official voices prevailed over the perspectives defended by civil society actors; finally, (3) there is a strong suspicion that readers scarcely had the opportunity to understand the meaning of the policy at stake, once the coverage was superficial and not plural.
Hepatite C
Strauss Edna
Revista da Sociedade Brasileira de Medicina Tropical , 2001,
Abstract: Estima-se que cerca de 3% da popula o mundial esteja infectada pelo vírus da hepatite C. Todos os que receberam transfus o de sangue ou seus componentes e os usuários de drogas podem estar infectados. Procedimentos odontológicos, médicos, tatuagem ou acupuntura também constituem fatores de risco. A infec o se cronifica em até 85% dos indivíduos, com evolu o assintomática durante anos ou décadas e apresenta o clínica variada. Para o diagnóstico, a determina o do anti-VHC revela-se muito sensível e a confirma o se faz pela determina o do RNA-VHC no sangue; o estadiamento da doen a e a avalia o da atividade inflamatória pela biópsia hepática. O tratamento objetiva deter a progress o da doen a hepática através da inibi o da replica o viral. Devido à baixa eficácia terapêutica aliada a importantes efeitos colaterais do interferon e da ribavirina, esses medicamentos encontram indica es e contra-indica es específicas. Vários fatores preditivos de resposta ao tratamento, principalmente a carga viral e o genótipo do VHC, mostram-se úteis na avalia o dos pacientes.
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