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Search Results: 1 - 10 of 5779 matches for " Douglas Moote "
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The Impact of Enteric Contrast on Radiologist Confidence in Intravenously Enhanced MDCT of the Abdomen and Pelvis: A Randomized Controlled Trial  [PDF]
Christopher M. Garcia, Steven Boe, Bret Coughlin, David M. O’Sullivan, Douglas Moote, Michael T. O’Loughlin, Devika Jajoo, Steve Lee
Advances in Computed Tomography (ACT) , 2014, DOI: 10.4236/act.2014.32004
Abstract:

After Institutional Review Board approval, 109 patients ≥ 18 years old undergoing intravenously enhanced Computed Tomography (CT) of the abdomen and pelvis were prospectively enrolled and randomized into two arms. Patients with a history of inflammatory bowel disease, Crohn disease and ulcerative colitis were excluded. The control arm received routine enteric contrast and intravenous contrast. The experimental arm did not receive oral contrast, but received the standard dose of intravenous (IV) contrast. One of four experienced body radiologists reviewed the studies and rated his/her confidence on a scale of 1 (no confidence) to 10 (all confident findings have been made). Confidence levels were compared between groups. The 109 subjects were distributed 54 (49.5%) in the control arm and 55 (50.5%) in the experimental arm. The average confidence level in the control arm was 8.7 ± 0.9 versus 8.4 ± 1.1 in the experimental arm, which is not statistically significant (p value = 0.09). Among radiologists, the average confidence levels ranged from 6 - 10 in the control arm and 7 - 10 in the experimental arm. No examinations were repeated for technical considerations in either group. No studies were repeated in the experimental group in order to administer oral contrast. When each radiologist was compared to the others, there were no differences in confidence level between pairs in the control arm; however, there were statistically significant differences in confidence level among three pairs of radiologists for the experimental arm. There was no statistically significant difference in radiologist confidence level between intravenously enhanced abdomen and pelvis CTs with enteric contrast and without enteric contrast.

Allergen-specific immunotherapy
Moote William,Kim Harold
Allergy, Asthma & Clinical Immunology , 2011, DOI: 10.1186/1710-1492-7-s1-s5
Abstract: Allergen-specific immunotherapy is a potentially disease-modifying therapy that is effective for the treatment of allergic rhinitis/conjunctivitis, allergic asthma and stinging insect hypersensitivity. However, despite its proven efficacy in these conditions, it is frequently underutilized in Canada. The decision to proceed with allergen-specific immunotherapy should be made on a case-by-case basis, taking into account individual patient factors such as the degree to which symptoms can be reduced by avoidance measures and pharmacological therapy, the amount and type of medication required to control symptoms, the adverse effects of pharmacological treatment, and patient preferences. Since this form of therapy carries the risk of anaphylactic reactions, it should only be prescribed by physicians who are adequately trained in the treatment of allergy. Furthermore, injections must be given under medical supervision in clinics that are equipped to manage anaphylaxis. In this article, the authors review the indications and contraindications, patient selection criteria, and the administration, safety and efficacy of allergen-specific immunotherapy.
CSACI Position statement on the testing of food-specific IgG
Carr Stuart,Chan Edmond,Lavine Elana,Moote William
Allergy, Asthma & Clinical Immunology , 2012, DOI: 10.1186/1710-1492-8-12
Abstract:
Democratic Centralism in Revolutionary China: Tensions within a People’s Democratic Dictatorship  [PDF]
Douglas Howland
Open Journal of Philosophy (OJPP) , 2017, DOI: 10.4236/ojpp.2017.74024
Abstract: Democratic centralism was a revolutionary strategy to reorganize society in China after 1949; it was the key governing aspect of Mao Zedong’s “people’s democratic dictatorship.” This essay explores the tensions between democracy and centralization in the practice of democratic centralism in 1950s Shanghai. Youth and workers groups reports reveal a high degree of commitment to open debate, elections, self-organization, and new forms of leadership. Other priorities, however—a strong central state regime—would come to dominate and, after 1957, centralism and unity cancelled democracy.
Carl Schmitt’s Turn to Sovereignty in Jurisprudence  [PDF]
Douglas Howland
Beijing Law Review (BLR) , 2018, DOI: 10.4236/blr.2018.92015
Abstract: Carl Schmitt’s early proposal to better unify the liberal state, by locating sovereignty in the executive, proved a disaster with the National Socialist regime. But sovereignty concerns a state’s internal as well as international relations, and Schmitt came to argue in the 1940s that an authoritative and sovereign form of international law might offer standards for unifying states within an international community, much as the Catholic Church once provided an intra-state source of law and authority. Unlike recent work that emphasizes Nomos, Großraum, or “institutional thinking,” this essay argues that Schmitt sought such a sovereign jurisprudence in the decisions of judges and justified it with the conservative claims of historical continuity.
Consensus Guidelines on Practical Issues of Immunotherapy-Canadian Society of Allergy and Clinical Immunology (CSACI)
Eric Leith, Tom Bowen, Joe Butchey, David Fischer, Harold Kim, Bill Moote, Peter Small, Don Stark, Susan Waserman
Allergy, Asthma & Clinical Immunology , 2006, DOI: 10.1186/1710-1492-2-2-47
Abstract: The early phase of the immediate hypersensitivity reaction results from the release of mediators from mast cells or basophils, the key effector cells in the allergic reaction. High-affinity receptors on mast cells and basophils bind immunoglobulin E (IgE). When a multivalent allergen binds its specific IgE, the high-affinity receptors are cross-linked, leading to a cascade of events that result in mast cell and basophil degranulation. The resulting mediators and growth factors are also associated with the late-phase allergic response and with chronic inflammation. Eosinophils and neutrophils are attracted by chemotactic factors to the site of an immediate hypersensitivity reaction; in chronic allergic reactions, mononuclear cell infiltrates are also found. The inflammatory response has features of cellular and humoral immunity, and it results from a network of interacting soluble mediators, cytokines, and chemokines [7].Randomized double-blind placebo-controlled (RDBPC) studies have shown that immunotherapy is effective for the treatment of allergic rhinitis, allergic asthma, and hypersensitivity to insect stings [8]. The efficacy of subcutaneous specific immunotherapy has been documented in RDBPC studies of allergic rhinitis (and usually conjunctivitis) induced by birch, grass, ragweed, and Parietaria pollens; house dust mite; cat; and Alternaria[2]. The beneficial effects of immunotherapy on asthma have been shown in regard to grass and ragweed pollen, house dust mites, cat, Cladosporium, and Alternaria[6,9]. Venom immunotherapy has proven to be an effective treatment for individuals at risk of anaphylaxis from yellowjacket, wasp, honeybee, white-faced hornet, and yellow hornet stings. Recently, fire ant whole-body extract has become available for immunotherapy [10]. Latex, peanut, and cockroach allergens are under investigation [11-13].Once signs and symptoms consistent with an allergic disease have been identified, a skin test demonstrating allergen-specific IgE
Information Content Inclusion Relation and its Use in Database Queries  [PDF]
Junkang Feng, Douglas Salt
Journal of Software Engineering and Applications (JSEA) , 2010, DOI: 10.4236/jsea.2010.33031
Abstract: A database stores data in order to provide the user with information. However, how a database may achieve this is not always clear. The main reason for this seems that we, who are in the database community, have not fully understood and therefore clearly defined the notion of “the information that data in a database carry”, in other words, “the information content of data”. As a result, databases’ capability is limited in terms of answering queries, especially, when users explore information beyond the scope of data stored in a database, the database normally cannot provide it. The underlying reason of the problem is that queries are answered based on a direct match between a query and data (up to aggregations of the data). We observe that this is because the information that data carry is seen as exactly the data per se. To tackle this problem, we propose the notion of information content inclusion relation, and show that it formulates the intuitive notion of the “information content of data” and then show how this notion may be used for the derivation of information from data in a database.
Paradigm Consistency and the Depiction of Stiltedness: The Case of than I versus than me  [PDF]
Douglas J. Wulf
Open Journal of Modern Linguistics (OJML) , 2012, DOI: 10.4236/ojml.2012.23014
Abstract: Close adherence to prescriptive rules of grammar can sometimes produce stilted language, which can impart to language a pompous or stuffy impression. It is ironic that an island of potential unacceptability can arise within what is regarded as Standard English. In instances where prescriptive grammaticality and sociolinguistic appropriateness are in opposition, disagreements over language use can occur. Despite its impact, stiltedness has received little scholarly attention, probably because it is an intangible, subjective phenomenon. This paper investigates an indirect way to depict stiltedness through a quantitative measure. The example selected to demonstrate this approach is the rule of bare pronouns in comparative sentences. With tangible quantitative measurements of paradigm consistency and inconsistency, stiltedness may perhaps be understood more effectively.
Assessing the Sensitivity of Climate Change Targets to Policies of Land Use, Energy Demand, Low Carbon Energy and Population Growth  [PDF]
Douglas Crawford-Brown
Journal of Environmental Protection (JEP) , 2012, DOI: 10.4236/jep.2012.312178
Abstract: A reduced scale model of the coupled carbon cycle, population dynamics, energy system and land use characteristics is used to assess the sensitivity of atmospheric carbon to a variety of policies. Policies simulated include reduction of the rate of growth of the population; reduction of the rate of conversion of forested land to cropland; reduction in per capita energy demand in developed nations; reduction in per capita energy demand in developing nations; reduction in the carbon intensity of energy production in developed nations; and reduction in the carbon intensity of energy production in developing nations. For each policy, both the time to onset of the policy and the fractional annual rate of change in the associated model variable are established. Using as a measure of sensitivity the extension in years required for atmospheric carbon to reach the policy ceiling of 1160 BMT, achieved at a policy that introduces a rate of change in each affected model variable of 0.05 per year (a 5% change per year), then the policies in decreasing order of sensitivity are: Developing nations per capita growth (17 years), Developing nations carbon intensity (17 years), Population control (11 years), Developed nations carbon intensity (2.9 years), Developed nations per capita growth (2.8 years) and Land use (1.3 years). These values are all approximately doubled when population is stabilised first. An analysis of the model results also shows a convergence of the developed and developing nations per capita carbon emissions by 2100 when a portfolio of policies is selected to prevent a doubling of the pre-industrial revolution level of atmospheric carbon at any point in the future, consistent with a principle of “contract and converge”.
Does Aristotle Refute the Harmonia Theory of the Soul?  [PDF]
Douglas J. Young
Open Journal of Philosophy (OJPP) , 2013, DOI: 10.4236/ojpp.2013.31008
Abstract:

In Aristotle’s On the Soul he considers and refutes two versions of the harmonia theory of the soul’s relation to the body. According to the harmonia theory, the soul is to the body what the tuning of a musical instrument is to its material parts. Though he believes himself to have entirely dismissed the view, he has not. I argue that Aristotle’s hylomorphic account is, in fact, an instance of the harmonia theory.

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