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Cross-Family Translational Genomics of Abiotic Stress-Responsive Genes between Arabidopsis and Medicago truncatula
Daejin Hyung, Chaeyoung Lee, Jin-Hyun Kim, Dongwoon Yoo, Young-Su Seo, Soon-Chun Jeong, Jai-Heon Lee, Youngsoo Chung, Ki-Hong Jung, Douglas R. Cook, Hong-kyu Choi
PLOS ONE , 2014, DOI: 10.1371/journal.pone.0091721
Abstract: Cross-species translation of genomic information may play a pivotal role in applying biological knowledge gained from relatively simple model system to other less studied, but related, genomes. The information of abiotic stress (ABS)-responsive genes in Arabidopsis was identified and translated into the legume model system, Medicago truncatula. Various data resources, such as TAIR/AtGI DB, expression profiles and literatures, were used to build a genome-wide list of ABS genes. tBlastX/BlastP similarity search tools and manual inspection of alignments were used to identify orthologous genes between the two genomes. A total of 1,377 genes were finally collected and classified into 18 functional criteria of gene ontology (GO). The data analysis according to the expression cues showed that there was substantial level of interaction among three major types (i.e., drought, salinity and cold stress) of abiotic stresses. In an attempt to translate the ABS genes between these two species, genomic locations for each gene were mapped using an in-house-developed comparative analysis platform. The comparative analysis revealed that fragmental colinearity, represented by only 37 synteny blocks, existed between Arabidopsis and M. truncatula. Based on the combination of E-value and alignment remarks, estimated translation rate was 60.2% for this cross-family translation. As a prelude of the functional comparative genomic approaches, in-silico gene network/interactome analyses were conducted to predict key components in the ABS responses, and one of the sub-networks was integrated with corresponding comparative map. The results demonstrated that core members of the sub-network were well aligned with previously reported ABS regulatory networks. Taken together, the results indicate that network-based integrative approaches of comparative and functional genomics are important to interpret and translate genomic information for complex traits such as abiotic stresses.
On the capacity limit of wireless channels under colored scattering
Wooseok Nam,Dongwoon Bai,Jungwon Lee,Inyup Kang
Mathematics , 2012,
Abstract: It has been generally believed that the multiple-input multiple-output (MIMO) channel capacity grows linearly with the size of antenna arrays. In terms of degrees of freedom, linear transmit and receive arrays of length $L$ in a scattering environment of total angular spread $|\Omega|$ asymptotically have $|\Omega| L$ degrees of freedom. In this paper, it is claimed that the linear increase in degrees of freedom may not be attained when scattered electromagnetic fields in the underlying scattering environment are statistically correlated. After introducing a model of correlated scattering, which is referred to as the colored scattering model, we derive the number of degrees of freedom. Unlike the uncorrelated case, the number of degrees of freedom in the colored scattering channel is asymptotically limited by $|\Omega| \cdot \min \{L, 1/\Gamma}$, where $\Gamma$ is a parameter determining the extent of correlation. In other words, for very large arrays in the colored scattering environment, degrees of freedom can get saturated to an intrinsic limit rather than increasing linearly with the array size.
Beam Selection Gain Versus Antenna Selection Gain
Dongwoon Bai,Saeed S. Ghassemzadeh,Robert R. Miller,Vahid Tarokh
Mathematics , 2009,
Abstract: We consider beam selection using a fixed beamforming network (FBN) at a base station with $M$ array antennas. In our setting, a Butler matrix is deployed at the RF stage to form $M$ beams, and then the best beam is selected for transmission. We provide the proofs of the key properties of the noncentral chi-square distribution and the following properties of the beam selection gain verifying that beam selection is superior to antenna selection in Rician channels with any $K$-factors. Furthermore, we find asymptotically tight stochastic bounds of the beam selection gain, which yield approximate closed form expressions of the expected selection gain and the ergodic capacity. Beam selection has the order of growth of the ergodic capacity $\mathnormal{\Theta}(\log(M))$ regardless of user location in contrast to $\mathnormal{\Theta}(\log(\log(M)))$ for antenna selection.
Epithelioid sarcoma of the spine: a case report and review  [PDF]
Jeong Hyun Yoo
Open Journal of Clinical Diagnostics (OJCD) , 2011, DOI: 10.4236/ojcd.2011.11001
Abstract: Epithelioid sarcoma is a rare malignant soft tissue neoplasm commonly involving extremities of young adults and rarely occurring in the trunk area. It re-sembles a chronic inflammatory process and mimics benign reactive granuloma or other benign diseases. Despite its indolence and slow growth, the prognosis is poor with high recurrence and early lymph node spreading and hematogeneous distant metastasis. Involvement of the spine is extremely rare and diffi-cult to diagnose correctly in clinical presentation and pathology. We describe our experience a case of epi-thelioid sarcoma involving lumbar spine. A pre-ope- rative spine MRI showed a large solid and necrotic paraspinal mass which extended into the spinal canal with cord compression, and bone destruction. Final correct diagnosis was confirmed by immunohisto-chemical studies. When young adults present with a spinal lesion that has unusual large necrotic soft tissue mass, immunohistochemical studies are recommended for promptly determining the possibility of spinal epithelioid sarcoma.
Gender differences of health behaviors and quality of life of Koreans with asthma  [PDF]
Yeonsoo Jang, Hyera Yoo
Open Journal of Nursing (OJN) , 2013, DOI: 10.4236/ojn.2013.36057

Purpose: The purpose of this study was to explore gender differences in health-behaviors and quality of life (QOL) in Koreans with asthma. Methods: Participants, selected from the 2009 Korean National Health and Nutritional Examination Survey VI, included 305 individuals (men = 128, women = 177) with asthma and over 19 years old. Health behaviors were measured by questions about disease management, health choices, and functional and psychological status. QOL was measured with the European Quality of Life-5D (EQ-5D). Results: In health behaviors, 51.3% of women and 37.7% of men suffered from wheezing at rest. About 41% of men and 10% of women were smokers. One half of the participants were not taking medication and this was not significantly different by gender. The number of women with symptoms of depression was significantly higher than men. The EQ-5D index score of women was significantly lower than that of men. Conclusion: Women with asthma were more likely to have psychological problems and discomfort than men. Understanding gender differences in asthma is important to the development of effective, tailored asthma management strategies to cope with symptoms and improve health behaviors and QOL for people with asthma.

DVL/RPM Based Velocity Filter Aiding in the Underwater Vehicle Integrated Inertial Navigation System  [PDF]
Tae Suk Yoo
Journal of Sensor Technology (JST) , 2014, DOI: 10.4236/jst.2014.43015
Abstract: The purpose of this paper is to design a DVL-RPM based VKF (Velocity Kalman Filter) design for a performance improvement underwater integrated navigation system. The integrated navigation sensor using DVL (Doppler Velocity Log) is widely used to improve the underwater navigation performance. However, the DVL’s range of measuring varied depending on the characteristics of sensor. So, if the sea gets too deep suddenly, it cannot measure the velocity. To complement such a weak point, the VKF was additionally designed, which was made of DVL, RPM (Revolve Per Minutes) of motor, and ES (Echo Sounder). The proposed approach relies on a VKF, augmented by an altitude from ES based switching architecture to yield robust performance, even when DVL exceeds the measurement range and the measured value is unable to be valid. The proposed approach relies on two parts: 1) indirect feedback navigation Kalman filter design, 2) VKF design. To evaluate the proposed method, we compare the VKF aided navigation system with PINS (Pure Inertial Navigation System) and conventional INS-DVL navigation system through simulation results. Simulations illustrate the effectiveness of the underwater navigation system assisted by the additional DVL-RPM based VKF in underwater environment.
Electroencephalography Analysis Using Neural Network and Support Vector Machine during Sleep  [PDF]
JeeEun Lee, Sun K. Yoo
Engineering (ENG) , 2013, DOI: 10.4236/eng.2013.55B018
Abstract: The purpose of this paper is to analyze sleep stages accurately using fast and simple classifiers based on the frequency domain of electroencephalography(EEG) signal. To compare and evaluate system performance, the rules of Rechtschaffen and Kales(R&K rule) were used. Parameters were extracted from preprocessing process of EEG signal as feature vectors of each sleep stage analysis system through representatives of back propagation algorithm and support vector machine (SVM). As a result, SVM showed better performance as pattern recognition system for classification of sleep stages. It was found that easier analysis of sleep stage was possible using such simple system. Since accurate estimation of sleep state is possible through combination of algorithms, we could see the potential for the classifier to be used for sleep analysis system.
Synthesizing Nanoparticles Using Reactions Occurring in Aerosol Phases  [PDF]
Ho Yeon Yoo, Stanley Bruckenstein
Advances in Nanoparticles (ANP) , 2013, DOI: 10.4236/anp.2013.24042

Our ultimate objective is to form nanoparticles by merging oppositely charged nanodroplets containing different constituents of the nanoparticle and construct a desktop apparatus to do this. These nanodroplets will be in oppositely charged aerosols originating from oppositely charged solutions containing the different component of the nanoparticle. In this paper, as the first stage in establishing the feasibility of this concept, we demonstrate that droplets formed from uncharged solutions will merge and the product of such reactions is the same as when their bulk solutions are mixed. We demonstrate that this is the case for three classes of reactions: the chemiluminescent reaction between Luminol and Potassium Ferricyanide, the pH sensitive fluorescence of Umbelliferone and the precipitation of Silver Chromate by reaction of Silver Nitrate with Potassium Chromate. We present arguments that our future goal using oppositely charged droplets is more efficient synthetically and will produce a narrow distribution of nanoparticle sizes.

Compactness in product spaces
WonSok Yoo
Pure Mathematical Sciences , 2012,
Isocurvature Constraints and Gravitational Ward Identity
Hojin Yoo
Physics , 2013,
Abstract: Axions and WIMPZILLAs are well-motivated dark matter candidates with interesting cos- mological implications, such as isocurvature perturbations and non-Gaussianities. How- ever, these predicted implications in the literature are based on the assumption that the cross-correlation between curvature and CDM isocurvature is negligible. This contribution discusses the cross-correlation in the axion and the WIMPZILLA scenarios. Particularly, it is shown that the gravitational Ward identity associated with diffeomorphism invariance plays an important role in this cross-correlation calculation confirming the assumption.
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