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Search Results: 1 - 10 of 50044 matches for " Dong-Hyo Lee "
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Cupping for Treating Pain: A Systematic Review
Jong-In Kim,Myeong Soo Lee,Dong-Hyo Lee,Kate Boddy,Edzard Ernst
Evidence-Based Complementary and Alternative Medicine , 2011, DOI: 10.1093/ecam/nep035
Abstract: The objective of this study was to assess the evidence for or against the effectiveness of cupping as a treatment option for pain. Fourteen databases were searched. Randomized clinical trials (RCTs) testing cupping in patients with pain of any origin were considered. Trials using cupping with or without drawing blood were included, while trials comparing cupping with other treatments of unproven efficacy were excluded. Trials with cupping as concomitant treatment together with other treatments of unproven efficacy were excluded. Trials were also excluded if pain was not a central symptom of the condition. The selection of studies, data extraction and validation were performed independently by three reviewers. Seven RCTs met all the inclusion criteria. Two RCTs suggested significant pain reduction for cupping in low back pain compared with usual care (P < .01) and analgesia (P < .001). Another two RCTs also showed positive effects of cupping in cancer pain (P < .05) and trigeminal neuralgia (P < .01) compared with anticancer drugs and analgesics, respectively. Two RCTs reported favorable effects of cupping on pain in brachialgia compared with usual care (P = .03) or heat pad (P < .001). The other RCT failed to show superior effects of cupping on pain in herpes zoster compared with anti-viral medication (P = .065). Currently there are few RCTs testing the effectiveness of cupping in the management of pain. Most of the existing trials are of poor quality. Therefore, more rigorous studies are required before the effectiveness of cupping for the treatment of pain can be determined. 1. Introduction Pain is the most common reason for seeking therapeutic alternatives to conventional medicine [1] and the more severe the pain, the more frequent is the use of such therapies [1, 2]. Frequently used treatments include acupuncture, massage and mind-body therapies [1, 2]. Cupping is a physical treatment used by acupuncturists or other therapists, which utilize a glass or bamboo cup to create suction on the skin over a painful area or acupuncture point [3]. It is mostly used in Asian and Middle Eastern countries and has been claimed to reduce pain as well as a host of other symptoms [4]. There are two types of cupping. Dry cupping pulls the skin into the cup without drawing blood. In wet cupping the skin is lacerated so that blood is drawn into the cup. A recent systematic review included five trials (two randomized clinical trials (RCTs) and three controlled clinical trials (CCTs)) on the effects of wet cupping on musculoskeletal problems [5]. Its findings suggested
Moxibustion for ulcerative colitis: a systematic review and meta-analysis
Dong-Hyo Lee, Jong-In Kim, Myeong Soo Lee, Tae-Young Choi, Sun-Mi Choi, Edzard Ernst
BMC Gastroenterology , 2010, DOI: 10.1186/1471-230x-10-36
Abstract: We searched the literature using 18 databases from their inception to February 10, 2010, without language restrictions. We included randomized clinical trials (RCTs), in which human patients with UC were treated with moxibustion. Studies were included if they were placebo-controlled or controlled against a drug therapy or no treatment group. The methodological quality of all RCTs was assessed using the Cochrane risk of bias.In total, five RCTs were included. All were of low methodological quality. They compared the effects of moxibustion with conventional drug therapy. Three tested moxibustion against sulfasalazine and two against sulfasalazine plus other drugs. A meta-analysis of five RCTs showed favorable effects of moxibustion on the response rate compared to conventional drug therapy (n = 407; risk ratio = 1.24, 95% CI = 1.11 to 1.38; P < 0.0001; heterogeneity: I2 = 16%).Current evidence is insufficient to show that moxibustion is an effective treatment of UC. Most of included trials had high risk of bias. More rigorous studies seem warranted.Ulcerative colitis (UC) is a common, chronic idiopathic inflammatory bowel disease (IBD) [1]. Patients typically present with bloody diarrhea, passage of pus, mucus, or both, and abdominal cramping during bowel movements [2]. UC often requires lifelong medication, but poor adherence to medication has been an important barrier to successful management. Relapse rates are high, and the risk of colorectal cancer has increased [3,4].Complementary and alternative medicine (CAM) is increasingly used for treatment of IBD [5], and acupuncture and moxibustion are particularly popular options. Moxibustion is a traditional Oriental medicine that uses the heat generated by burning herbal preparations containing Artemisia vulgaris to stimulate acupuncture points. Direct moxibustion is applied directly to the skin surface at an area around an acupuncture point, whereas indirect moxibustion is performed with some insulating materials (e.g.
Acupuncture for the treatment of tinnitus: a systematic review of randomized clinical trials
Jong-In Kim, Jun-Yong Choi, Dong-Hyo Lee, Tae-Young Choi, Myeong Soo Lee, Edzard Ernst
BMC Complementary and Alternative Medicine , 2012, DOI: 10.1186/1472-6882-12-97
Abstract: Fourteen databases were searched from the dates of their creation to July 4th, 2012. Randomized clinical trials (RCTs) were included if acupuncture was used as the sole treatment. The Cochrane risk of bias tool was used to assess the risk of bias.A total of 9 RCTs met all the inclusion criteria. Their methodological quality was mostly poor. Five RCTs compared the effectiveness of acupuncture or electroacupuncture with sham acupuncture for treating tinnitus. The results failed to show statistically significant improvements. Two RCTs compared a short one-time scalp acupuncture treatment with the use of penetrating sham acupuncture at non-acupoints in achieving subjective symptom relief on a visual analog scale; these RCTs demonstrated significant positive effects with scalp acupuncture. Two RCTs compared acupuncture with conventional drug treatments. One of these RCTs demonstrated that acupuncture had statistically significant effects on the response rate in patients with nervous tinnitus, but the other RCT did not demonstrate significant effects in patients with senile tinnitus.The number, size and quality of the RCTs on the effectiveness of acupuncture for the treatment of tinnitus are not sufficient for drawing definitive conclusions. Further rigorous RCTs that overcome the many limitations of the current evidence are warranted.
Bojungikgitang and banhabaekchulchonmatang in adult patients with tinnitus, a randomized, double-blind, three-arm, placebo-controlled trial - study protocol
Nam-Kwen Kim, Dong-Hyo Lee, Jung-Hun Lee, Yong-Leol Oh, In-Hwan Yoon, Eun-Sung Seo, Chung-Ho Lee
Trials , 2010, DOI: 10.1186/1745-6215-11-34
Abstract: We aim to establish basic clinical efficacy and safety data for bojungikgitang and banhabaekchulchonmatang, which are approved as herbal medications by the Korea Food and Drug Administration in adult patients with tinnitus.This study was a randomised, double-blind, placebo-controlled trial with three parallel arms (bojungikgitang, banhabaekchulchonmatang, and a placebo). Participants included in the study met the following criteria: typical conditions of intermittent or continuous tinnitus, for more than three months, with involuntary perceptions of the concept of a sound in the absence of an external source. Participants received bojungikgitang, banhabaekchulchonmatang, or a placebo-drug for eight weeks. The total duration of each arm was eleven weeks. Each participant was examined for signs and symptoms of tinnitus before and after taking medication. Post-treatment follow-up was performed two weeks after the final administration of medication.This trial provided evidence for the efficacy and safety of bojungikgitang and banhabaekchulchonmatang in adult patients with tinnitus. The primary outcome measure was the Tinnitus Handicap Inventory, an assessment used to identify difficulties that may be experienced due to tinnitus. The secondary measures were included an Acoustic Examination and the Visual Analogue Scale. We employed the Euro-Qol 5-Dimension and the Health Utilities Index Mark 3, a health-related quality of life questionnaire. Safety was assessed by complete blood cell count, erythrocyte sedimentation rate, blood chemistry, urine analysis, PA chest film, brain computed tomography, otologic examination, and vital signs.Current Controlled Trials ISRCTN23691284Tinnitus is a common disorder,[1] with approximately 5-15% of the general population experiencing an unremitting sensation of tinnitus [2]. Of patients who suffer with the condition, 1 to 2% are seriously impaired. Hearing loss, regardless of the cause, is the most important risk factor for the developm
Hwangryunhaedoktang in adult patients with Atopic Dermatitis: a randomised, double-blind, placebo-controlled, two-centre trial - study protocol
Nam-Kwen Kim, Dong-Hyo Lee, Hyung-Sik Seo, Seung-Ho Sun, Yong-Leol Oh, Ji-Eun Kim, In-Hwan Yoon, Eun-Sung Seo, Gye-Seon Shim, Christopher Zaslawski
BMC Complementary and Alternative Medicine , 2011, DOI: 10.1186/1472-6882-11-68
Abstract: We aim to establish basic clinical efficacy and safety data for Hwangryunhaedoktang, which is approved as an herbal medication by the Korean Food and Drug Administration, in adult patients with Atopic Dermatitis.This study is a randomised, double blind, placebo-controlled, two-centre trial with two parallel arms (Hwangryunhaedoktang and a placebo). The diagnosis of Atopic Dermatitis will be made according to the criteria of Hanifin and Rajka by two different Oriental medicine doctors. We will include participants experiencing typical conditions of intermittent or continuous Atopic Eczema for six or more months. Participants will receive Hwangryunhaedoktang or a placebo-drug for eight weeks. The total duration of each arm is eleven weeks. Each participant will be examined for signs and symptoms of Atopic Dermatitis before and after taking medication. A follow-up to evaluate the maintenance of safety will be performed two weeks after the final administration of medication.This trial will utilize high quality trial methodologies in accordance with consolidated standards of reporting trials guidelines. It will provide evidence for the clinical efficacy and safety evaluation of Hwangryunhaedoktang in adult patients with Atopic Dermatitis. Moreover, we will also employ health-related quality of life questionnaires to assess the changes in quality of life.Current Controlled Trials ISRCTN26218532Atopic Dermatitis (AD) is a chronic inflammatory pruritic skin disease that is often associated with other atopic disorders such as allergic rhinitis and asthma[1]. It is characterised by poorly defined erythema with oedema, vesiculation, and weeping in the acute stage and skin thickening (lichenification) in the chronic stage[2]. These irritating symptoms result in a severely reduced quality of life (QOL). In particular, itching that continues throughout the day and worsens at night causes sleep loss and impacts everyday activities and psychosocial well being [3,4].The prevalence o
Unexplained Perioperative Hypotension in a Patient Treated with Pine Needle Extract  [PDF]
Heeseung Lee, Heehun Jeon, Jong In Han, Youn Jin Kim, Chi Hyo Kim, Dong Yeon Kim
Open Journal of Anesthesiology (OJAnes) , 2013, DOI: 10.4236/ojanes.2013.31003

Pine needle-based products are popular dietary supplements in East Asia for health promotion. Pine needle extract (PNE) are especially known as potential anti-hypertensive and anti-lipidemic agents. We report a case of profound, long-lasting unexplained hypotension during and after anesthesia in a patient treated with PNE. Bedside transthorasic echocardiography (TTE) was used as a part of useful diagnostic modality.

Investigation on the insecticidal limonoid content of commercial biopesticides and neem extract using solid phase extraction  [PDF]
Ji-Won Lee, Cho-Long Jin, Ki Chang Jang, Geun-Hyoung Choi, Hee-Dong Lee, Jin Hyo Kim
Journal of Agricultural Chemistry and Environment (JACEN) , 2013, DOI: 10.4236/jacen.2013.24012
Abstract: Neem extract is an alternative insecticide for organic farming and is an allowed component for commercial biopesticide in Korea. However, crop protection properties are not consistent in commercial products. In this report, quantitative analysis of commercial biopesticides for the four insecticidal limonoids of neem extract-azadirachtin A, azadirachtin B, deacetylsalannin and salannin, was conducted through solid phase extraction method with lipophilic-hydrophilic balanced material. The recoveries of the four limonoids ranged from 80.5% to 105%, and their limit of quantitation ranged from 0.028 mg/L to 0.356 mg/L. On the five imported neem extracts, the total contents of the four bioactive limonoids extracted were from 321 mg/L to 5810 mg/L, but there were big variations in the relative composition of the limonoids. The total limonoidal concentrations in 23 commercial bio-pesticides made from neem showed from below LOQ to 7190 mg/L with significant differences in the relative composition. These differences determine the biopesticide’s efficacy on pests, therefore, tracking the active ingredients is necessary for the quality control of commercial bio-pesticides.
Bubble and Heat Transfer Phenomena in Viscous Slurry Bubble Column  [PDF]
Hyo Sik Kim, Jin Ho Kim, Chan Gi Lee, Suk Hwan Kang, Kwang Jae Woo, Ho Jin Jung, Dong Wook Kim
Advances in Chemical Engineering and Science (ACES) , 2014, DOI: 10.4236/aces.2014.44046
Abstract: Heat transfer and bubble phenomena were investigated by adopting the drift flux model in a viscous slurry bubble column reactor (SBCR), having a diameter of 0.0508 m(ID) and height 1.5 m. The effects of superficial gas velocity (0.002 -0.164 m/s), solid concentration (0 - 20 wt%) and liquid viscosity (paraffin oil; 16.9 mPas and squalane; 25.9 mPas) on the gas holdup and heat transfer characteristics were examined. It was observed that the gas holdup increased with increasing superficial gas velocity (UG), but decreased with increasing solid concentration (SC) or slurry viscosity. The degree of non-uniformity in a SBCR could be determined by the modified drift flux model at the heterogeneous flow regime. The local heat transfer coefficient (h) between the immersed heater and the bed decreased with increasing liquid viscosity and SC, but it increased with increasing UG. The modified Nusselt number including the gas holdup and local heat transfer coefficient was well correlated in terms of dimensionless groups such as Reynolds and Prandtl numbers.
Fault Detection of Roller-Bearings Using Signal Processing and Optimization Algorithms
Dae-Ho Kwak,Dong-Han Lee,Jong-Hyo Ahn,Bong-Hwan Koh
Sensors , 2014, DOI: 10.3390/s140100283
Abstract: This study presents a fault detection of roller bearings through signal processing and optimization techniques. After the occurrence of scratch-type defects on the inner race of bearings, variations of kurtosis values are investigated in terms of two different data processing techniques: minimum entropy deconvolution (MED), and the Teager-Kaiser Energy Operator (TKEO). MED and the TKEO are employed to qualitatively enhance the discrimination of defect-induced repeating peaks on bearing vibration data with measurement noise. Given the perspective of the execution sequence of MED and the TKEO, the study found that the kurtosis sensitivity towards a defect on bearings could be highly improved. Also, the vibration signal from both healthy and damaged bearings is decomposed into multiple intrinsic mode functions (IMFs), through empirical mode decomposition (EMD). The weight vectors of IMFs become design variables for a genetic algorithm (GA). The weights of each IMF can be optimized through the genetic algorithm, to enhance the sensitivity of kurtosis on damaged bearing signals. Experimental results show that the EMD-GA approach successfully improved the resolution of detectability between a roller bearing with defect, and an intact system.
An Objective Pronator Drift Test Application (iPronator) Using Handheld Device
Soojeong Shin, Eunjeong Park, Dong Hyun Lee, Ki-Jeong Lee, Ji Hoe Heo, Hyo Suk Nam
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0041544
Abstract: Background The pronator drift test is widely used to detect mild arm weakness. We developed an application that runs on a handheld device to objectify the pronator drift test and investigated its feasibility in stroke patients. Methods The iPronator application, which uses the built-in accelerometer in handheld devices, was developed. We enrolled acute ischemic stroke patients (n = 10) with mild arm weakness and healthy controls (n = 10) to validate the iPronator. In addition to conventional neurological examinations, the degree of average, maximum, and oscillation in drift and pronation were measured and compared using the iPronator. Follow-up tests using the iPronator were also conducted in the patient group one week later. Results There was a strong correlation between the average degree of pronation and drift measured by the iPronator (r = 0.741, p<0.001). The degrees of average and maximum in pronation were greater in the patient group than in the control group [in average, 28.9°, interquartile range (IQR) 18.7–40.3 vs. 3.8° (IQR 0.3–7.5), p<0.001], in maximum, 33.0° (IQR 24.0–52.1) vs. 6.2° (IQR 1.4–9.4), p<0.001]. The degree of oscillation in pronation was not different between the groups (p = 0.166). In drift, the degrees of average, maximum, and oscillation were greater in the patient group. In stroke patients, a follow-up study at one week revealed improvements in the degrees of pronation and drift compared with baseline parameters. Conclusions The iPronator can reliably detect mild arm weakness of stroke patients and was also useful in detecting functional recovery for one week in patients with acute stroke.
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