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Search Results: 1 - 10 of 82 matches for " Dionyssia-Pinelopi Carrer "
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Compartmentalization of lipid peroxidation in sepsis by multidrug-resistant gram-negative bacteria: experimental and clinical evidence
Chryssoula Toufekoula, Vassileios Papadakis, Thomas Tsaganos, Christina Routsi, Stylianos E Orfanos, Anastasia Kotanidou, Dionyssia-Pinelopi Carrer, Maria Raftogiannis, Fotini Baziaka, Evangelos J Giamarellos-Bourboulis
Critical Care , 2013, DOI: 10.1186/cc11930
Abstract: Lethal sepsis was induced in rats by the intraperitoneal injection of one MDR isolate of Pseudomonas aeruginosa. Produced malondialdehyde (MDA) was measured in tissues 5 hours after bacterial challenge with the thiobarbiturate assay followed by high-performance liquid chromatography (HPLC) analysis. Results were compared with those from a cohort of patients with ventilator-associated pneumonia (VAP) and sepsis by MDR Gram-negative bacteria. More precisely, serum MDA was measured on 7 consecutive days, and it was correlated with clinical characteristics.MDA of septic rats was greater in the liver, spleen, and aortic wall, and it was lower in the right kidney compared with sham operated-on animals. Findings were confirmed by the studied cohort. Circulating MDA was greater in patients with hepatic dysfunction and acute respiratory distress syndrome (ARDS) compared with patients without any organ failures. The opposite was found for patients with acute renal dysfunction. No differences were found between patients with ARDS without or with cardiovascular (CV) failure and patients without any organ failure. Serial measurements of MDA in serum of patients indicated that levels of MDA were greater in survivors of hepatic dysfunction and ARDS and lower in survivors of acute renal dysfunction.Animal findings and results of human sepsis are complementary, and they suggest a compartmentalization of lipid peroxidation in systemic infections by MDR gram-negative bacteria.Oxidative stress results from an imbalance between production of reactive oxygen and nitrogen species (ROS and RNS) and endogenous antioxidant defense mechanisms [1]. A growing body of evidence suggests that many of the effects of cellular dysfunction under oxidative stress are mediated by products of nonenzymatic reactions, such as the peroxidative degradation of polyunsaturated fatty acids. Aldehyde molecules generated during lipid peroxidation are considered ultimate mediators of toxic effects elicited by oxid
Isolation of Aerobic Bacteria in Internal Specimens from Domesticated Pigs Used in Biomedical Research and the Association with Bacterial Translocation
Evangelia Gkiza,Evangelos Giamarellos-Bourboulis,Thomas Tsaganos,Theodoros Xanthos,Laskarina- Maria Korou,Dionyssia- Pinelopi Carrer,Spyros Stergiopoulos,Evangelia Kouskouni,Despina N. Perrea,Ismene A. Dontas
Journal of Animal and Veterinary Advances , 2012, DOI: 10.3923/javaa.2012.539.546
Abstract: Swine are extensively used in biomedical research as animal models. Although, ideally they are procured from specialized breeders of pathogen-free animals, animals from meat production farms may be used. The aim of the present study was to investigate the potential existence of subclinical disease of domestic pigs used for research. In order not to sacrifice additional animals, 46 pigs from two other studies in progress were investigated: group A, n = 24, aseptic minor procedures; group B, n = 22, similar procedures plus induction of ventricular fibrillation leading to Cardiac Arrest (CA). Microbiological cultures of blood, liver and lung tissues were execute. Overall 60% samples contained pathogenic or opportunistic pathogens protocol comparison demonstrated positive blood cultures in one animal of group A (4.2%) and 5 of group B (22.7%, p>0.05). Liver cultures were positive in two animals of group A (8.3%) and 15 of group B (68.2%, p = 0.0041). Lung cultures were positive in 10 animals of group A (41.7%) and 17 of group B (77.3%, p>0.05). Bordetella bronchiseptica was isolated in liver (10.8%) and lung cultures (26%) overall. There was a significant difference regarding Stenotrophomonas maltophilia, isolated at a greater rate in group B (liver p = 0.00007, lung p = 0.0043). This consisted an unexpected finding, leading to the assumption that group B animals may have sustained Bacterial Translocation (BT) through an intestinal ischemia/reperfusion mechanism due to CA. These results not only showed the impact the use of non pathogen-free animals may have on the results in research but also provided for the first time indication that CA may contribute to systemic infection early after successful resuscitation, by BT.
Silent Bodies in Religion and Work: Migrant Filipinas and the Construction of Relational Power
Pinelopi Topali
Religions , 2013, DOI: 10.3390/rel4040621
Abstract: The present article explores the relationship of silences, as vocal and non-vocal bodily practices, to forms of power in religion and work. More specifically, it focuses on Filipina domestic workers in Greece who are members of Iglesia ni Cristo, an independent Filipino church. In the hierarchical contexts of the church and paid domestic work, where the church expands its influence, silence is a dominant embodied religious ethos, an ideal behavior for female workers and an expression of obedience. This silence enhances women’s subordination resulting in strict power relationships. Silencing the body, however, is also an agential practice of Filipina immigrants themselves, a tool to transform power relationships into more reciprocal ones. By reflective and unreflective practices of bodily silence, migrant Filipinas reverse subjection, transform the power relationships in which they are involved and attribute to them a more relational character.
The relationship between customer satisfaction and the demographic profile of participants in the exercise programs of health and fitness clubs for municipal youth and sport organizations
Choregia , 2007,
Abstract: The objective of this study is to analyze the satisfaction of participants in the offered programs of exercise of health and fitness clubs for municipal Youth and Sport organizations. A random sample of 320 participants was selected from 18 closed halls and responded to a questionnaire that was pre-checked for reliability, validity and objectivity (Chen, 2001). The questionnaire included questions related to demographics, participant satisfaction from the exercise programs and from the level of organisation these have, the quality of equipment the athletic halls have and the variety of services offered. Data was analysed statistically to determine the relationships and differences between the mean value of the different variables. Results show that the profile of the major customer segment is women from 26 to 35 years old with University education. Also, statistical analysis shows that there are significant differences between the average values in all 5 dimensions of participant satisfaction: the prices of exercise programs, program content, the quality of hall equipment, public relations and employee performance. Also, there are statistically significant differences between the demographic variables (age, sex, income) and the 5 participant satisfaction dimensions. However, the dimensions that present statistically significant differences vary according to the demographic variable analysed. This shows that municipal sports centres should differentiate their offers according to the dimensions of satisfaction that are more important for each customer segment as these are formed based on age, income or sex.
Individualistic and Time-Varying Tree-Ring Growth to Climate Sensitivity
Marco Carrer
PLOS ONE , 2011, DOI: 10.1371/journal.pone.0022813
Abstract: The development of dendrochronological time series in order to analyze climate-growth relationships usually involves first a rigorous selection of trees and then the computation of the mean tree-growth measurement series. This study suggests a change in the perspective, passing from an analysis of climate-growth relationships that typically focuses on the mean response of a species to investigating the whole range of individual responses among sample trees. Results highlight that this new approach, tested on a larch and stone pine tree-ring dataset, outperforms, in terms of information obtained, the classical one, with significant improvements regarding the strength, distribution and time-variability of the individual tree-ring growth response to climate. Moreover, a significant change over time of the tree sensitivity to climatic variability has been detected. Accordingly, the best-responder trees at any one time may not always have been the best-responders and may not continue to be so. With minor adjustments to current dendroecological protocol and adopting an individualistic approach, we can improve the quality and reliability of the ecological inferences derived from the climate-growth relationships.
Contributo alla stima dei beni pubblici (pp. 1-20)
Piero Carrer
Aestimum , 1988,
Aspetti estimativi connessi con l'utilizzazione del suolo
Piero Carrer
Aestimum , 1984,
Una proposta metodologica di valutazione dell'avviamento in interventi di trasformazione
Piero Carrer
Aestimum , 1983,
Contributo alla stima dei beni pubblici (pp. 52-60)
Piero Carrer
Aestimum , 1988,
Contributo alla stima dei beni pubblici (pp. 21-51)
Piero Carrer
Aestimum , 1988,
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