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Search Results: 1 - 10 of 1824 matches for " Diabetic retinopathy "
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Diabetic retinopathy quiz
Community Eye Health Journal , 2011,
Abstract: Classify these photographs and say which patients must be referred to a retinal clinic.
CPD: test yourself (Diabetic retinopathy)
Community Eye Health Journal , 2011,
Abstract: Topic-based quiz designed to test your understanding.
Recognising and managing diabetic retinopathy
Anthony Hall
Community Eye Health Journal , 2011,
Abstract: The management of diabetic retinopathy (DR) depends on accurately recognising or classifying the different types of DR and knowing what treatment to give the patient.DR has clinical signs which can be seen with an ophthalmoscope or with a slit lamp and a 90- or 78-dioptre lens. The advantage of the slit lamp is that it allows you to visualise the retina with both eyes. This stereoscopic vision provides a sense of depth which aids diagnosis, particularly of macular oedema. Other aids to DR diagnosis are fundus photography, fluorescein angiography, and optical coherence tomography.
Diabetic retinopathy (DR): management and referral
Community Eye Health Journal , 2011,
Abstract: This diabetic retinopathy (DR) grading system is based on the International Council of Ophthalmology's diabetic retinopathy and diabetic macular oedema disease severity scales. At whatever level you work, you must encourage everyone with diabetes to manage their blood sugar and blood pressure. Refer them to available services for help if they are not sure how to do this, or if their control is poor.
Comparison of Established Risk Factors among Type 2 Diabetic Patients with or without Retinopathy in Golestan Hospital, Ahvaz 2010  [PDF]
Homeira Rashidi, Ali Kasiri, Seyed Mahmoud Latifi, Ferdos Zaman, Hajieh Shahbazian, Armaghan Moravej Aleali
Open Journal of Endocrine and Metabolic Diseases (OJEMD) , 2014, DOI: 10.4236/ojemd.2014.410022

The aim of this study was to establish diabetic retinopathy correlation with several risk factors. A prospective study including 256 type II diabetic patients who referred to diabetes’s clinic was designed. All patients underwent physical & retina examination and then completed questionnaire including duration of DM, cardiovascular disease, stroke, chronic kidney disease, smoking, and kind of treatment, blood pressure, BMI, abdominal & hip circumference. Results of HbA1C, total cholesterol, HDL & LDL cholesterol, TG, FBS, creatinine, 24-h urine microalbumin were recorded. Data were analyzed by SPSS version 17 with K2, independent samples T, and logistic regression. Of 256 types II diabetic patients 81 & 175 were men and women respectively. Mean age of subject was 54 ± 10.27. Prevalence of diabetic retinopathy was 22.3% & macula edema 0.5% & PDR 6% & NPDR 14%; diabetic retinopathy was associated with duration of DM & BMI (P = 0, P = 0.43 respectively). Mean of FBS 191 ± 83 vs. 165.7 ± 74.5 (P = 0.03), HbA1c 9.1 ± 2 vs. 8.5 ± 1.9 (P = 0.02), 24-h urine microalbumin 181.2 ± 404.7 vs. 60.2 ± 236 (P = 0.03), Systolic blood pressure 124.3 ± 21.3 vs. 118.5 ± 17.8 (p = 0.04) differed between diabetic patients with or without diabetic retinopathy. There were no significant difference between subject with & without diabetic retinopathy in total cholesterol LDL, HDL, TG, Cr, Diastolic BP, types of treatment, cardiovascular disease, chronic kidney disease, stroke & smoking. This study showed prevalence of diabetic retinopathy was high and it associated with duration of DM, BMI, FBS, HbA1C, 24-h urine albumin, and systolic blood pressure.

IL-4, IL-6, IL-10, IL-17A and vascular endothelial growth factor in the vitreous of patients with proliferative diabetic retinopathy  [PDF]
Valery Chernykh, Evgeny Smirnov, Yegor Varvarinsky, Dmitry Chernykh, Olga Obukhovа, Aleksandr Trunov
Advances in Bioscience and Biotechnology (ABB) , 2014, DOI: 10.4236/abb.2014.53023

In current article, results of the determination of the concentrations of vascular endothelial growth factor (VEGF), and some interleukins (IL-4, IL-6, IL-10, IL-17А) in the vitreous of patients with proliferative diabetic retinopathy are presented. We have found that in the mechanism of development of diabetic retinopathy, significant role plays an activation of local inflammation process and vascular proliferation. This is evidenced by a significant increase in the vitreous concentration of IL-4, IL-6, IL-10, IL-17A and vascular endothelial growth factor. Identified correlations between VEGF and IL-17A, between VEGF and IL-4, and between IL-17A and IL-4 show the relationship of inflammation and proliferation processes in the pathogenesis of diabetic retinopathy.

Rapid and Non-Invasive Screening System for Early Detection of Diabetic Retinopathy via Auto Fluorescence of Falvin Proteins  [PDF]
Bin Gao, Yang Li, Qifeng Jiang
Journal of Biomedical Science and Engineering (JBiSE) , 2018, DOI: 10.4236/jbise.2018.118017
Abstract: Diabetic retinopathy is one of the most serious complications of diabetes, which is also one of the most important causes of blindness around the world. Autofluorescence of flavin protein in retinal pigment epithelial cells is considered as a marker of early tissue damage. This study was designed to image spontaneous fluorescence of falvin proteins in fundus macular center area. The average intensity of the fluorescence signal and the characteristics of the histogram distribution were obtained and the significant differences in the fluorescence signals between the diabetic and the normal people were also compared with statistical methods, and then a rapid and non-invasive screening method and equipment for early detection of diabetic retinopathy were developed.
Retinopatia diabética
Bosco, Adriana;Lerário, Antonio Carlos;Soriano, Danilo;Santos, Rosa Ferreira dos;Massote, Píndaro;Galv?o, Daniela;Franco, Ana Cristina H. M.;Purisch, Saulo;Ferreira, Ant?nio Rodrigues;
Arquivos Brasileiros de Endocrinologia & Metabologia , 2005, DOI: 10.1590/S0004-27302005000200007
Abstract: diabetic retinopathy is a frequently observed complication in both type 1 and type 2 diabetes, specially in patients with long term disease and poor glicemic control. irreversible visual loss appears at the final stages of diabetic retinopathy and it is considered one of the most tragic of diabetic complications. it is also considered an important factor of morbidity and has a high economical impact once it is the leading cause of blindness. the pathophysiology of the retinal microvascular alterations is related to the chronic hyperglycemia that leads to the following circulatory disturbances: loss of vascular tonus, increase in vascular permeability, edema and exudation, with vascular obstruction and ischemia that stimulates neovascularization, which may lead to fibrous retraction and vitreous hemorrhages with retinal detachment. recent studies have indicated that the strict glicemic and blood pressure controls are effective in reducing or blocking the progression of retinopathy. up to now no pharmacological agents have shown to be effective in preventing or reducing neovascularization and visual loss. presently, the most effective available treatment for proliferative retinopathy is laser photocoagulation. further studies are needed to obtain new products and technologies that could effectively prevent or block retinopathy progression.
Relationship between diabetic retinopathy severity and the timespan between the endocrinopathy diagnosis and the first ophthalmic examination
Preti, Rony Carlos;Motta, Augusto Alves Lopes;Maia Júnior, Otacílio de O.;Morita, Celso;Nascimento, Vinícius Paganini;Monteiro, Mário Luiz Ribeiro;Takahashi, Walter Yukihiko;
Arquivos Brasileiros de Oftalmologia , 2010, DOI: 10.1590/S0004-27492010000300006
Abstract: purpose: to investigate whether the time interval between type 2 diabetes mellitus (dm) diagnosis and the first fundoscopic examination is related with the presence and the severity of diabetic retinopathy (dr) observed. methods: a survey of 105 type 2 dm patients referred to ophthalmologic evaluation in the "hospital das clinicas" (hc), university of s?o paulo medical school (uspms). results: regarding classification of dr in the 105 patients, 15 (14.28%) did not show signs of dr, and 90 (85.72%) exhibited them on fundoscopy. sixty patients underwent laser therapy, and 46.66% reported poor control of dm. only 15.23% of dm patients were adequately screened for dr on the first year of their dm diagnosis. among the 36 patients (34.30%) examined within five years of dm diagnosis, 58.33% did not present or demonstrate signs of mild dr and 22.20% of proliferative dr; 30 patients underwent an ophthalmologic examination after more than eleven years of dm diagnosis, 21.62% did not exhibit signs of dr and 59.46% were classified as proliferative dr. conclusion: this study showed a statistically significant relationship between the time interval from the diagnosis of type 2 dm and the first fundoscopic examination with the severity of dr.
Intravenous sodium fluorescein enhances the visibility of vitreous during vitrectomy surgery for diabetic retinopathy
Siqueira, Rubens Camargo;Jorge, Rodrigo;Canamary, Fabio;
Revista Brasileira de Oftalmologia , 2008, DOI: 10.1590/S0034-72802008000400005
Abstract: objective: to observe the effectiveness of intravenous sodium fluorescein visibility in the vitreous during vitrectomy surgery in patients with diabetic retinopathy. methods: fourteen consecutive cases of vitreoretinal surgery for vitreous hemorrhage and tractional retinal detachment secondary to diabetic retinopathy underwent intravenous injection of sodium fluorescein to 20% 1 hour before the surgery. the images of the steps of the surgeries were recorded. results: the sodium fluorescein stained green from the vitreous peripheral, vitreous base, posterior hyaloid, further improving visibility to a complete and more secure vitrectomy. the sodium fluorescein also stained fibrous points (sites of neovascularization) with high intensity making it easier its visibility. no complications associated with the dye injection were observed in all cases. conclusion: intravenous sodium fluorescein can be used safely for facilitating the observation of the vitreous, vitreous base, posterior hyaloid and sites of neovascularization. this technique can facilitate the process of vitrectomy in patients with diabetic retinopathy.
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