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Search Results: 1 - 10 of 63441 matches for " Denilson Jose Silva Feitosa-Junior "
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Comparison of Three Experimental Models for Rat Osteoarthritis Induction  [PDF]
Henrique Ribeiro Rodrigues-Neto, Edilson Ferreira Andrade-Junior, Denilson Jose Silva Feitosa-Junior, André Lopes Valente, Thiago Cesar Xavier, Bianca Caroline do Nascimento Alho, Renan Kleber Costa Teixeira, Fabio Vidal Moriya, Rui Sérgio Monteiro de Barros
Journal of Biosciences and Medicines (JBM) , 2016, DOI: 10.4236/jbm.2016.412010
Abstract: Background: Osteoarthritis is a slowly progressive and debilitating disease with high prevalence in adult population. Knee is one of the joints most affected by this disorder. There are several models for animals’ osteoarthritis induction, however it is not identified any paper that compares these techniques. The present study was aimed to define the most appropriate model for rats osteoarthritis induction. Material and Methods: 40 Wistar rats were distributed into 4 groups of 10 animals each: normality group (NG); meniscectomy group (MG); quinolone group (QG) and iodoacetate group (IG). Radiographic images of the rat’s knees were analyzed as well as the amount of chondrocytes in the epiphyseal and articular cartilage. Results: In the radiographic analysis, there was a low correlation between the raters. Regarding the amount of chondrocytes in the epiphyseal cartilage, it was noticed that the IG and QG groups had fewer chondrocytes than NG, in contrast to MG that reported similar results to normality (p > 0.05). There was no significant difference between IG and QG groups (p > 0.05). Regarding the amount of chondrocytes in articular cartilage, it was noticed that the IG group showed fewer chondrocytes than NG (p < 0.01), in contrast to the QG and MG groups that showed similar results to normality (p > 0.05). There was no significant difference between QG and MG groups (p > 0.05). Conclusion: Intraarticular injection of iodoacetate in rats is the model with greatest effect on reduction of chondrocytes amount.
Jose Otavio Carrera Silva Junior et al.
International Journal of Pharmaceutical Sciences and Research , 2011,
Abstract: Studies have been demonstrating that Vismia guianensis (Aubl.) Choisy, popularly known as seal, a species native to South America has high anticancer and antimicrobial potential. The objective of this study was to evaluate the antimicrobial activity of the ethanolic extract obtained from the leaves of V. guianensis, and trace its chemical profile. The phytochemical screening showed the presence of different phenolic compounds in the extract. The high performance liquid chromatography performed on the sub-fractions A and B from the ethyl acetate fraction traced the chemical composition profile of the ethanol extract, composed by benzophenone, xanthones and anthraquinones. The antimicrobial activity of the extract evaluated by agar diffusion method showed inhibition against Gram-positive bacteria: Streptococcus mitis (ATCC 903), Streptococcus sanguis (ATCC 10557) and Staphylococcus aureus (ATCC 6538) and the fungi: Candida albicans (ATCC 40175), Candida krusei (ATCC 40147) and Candida parapsilosis (ATCC 40038).
Jose Otavio Carrera Silva Junior et al.
International Journal of Pharmaceutical Sciences and Research , 2012,
Abstract: Vismia guianensis (Aubl.) Choisy is a tree that belongs to the secondary vegetation in rainforests. This study aimed to perform anatomy analysis by light microscopy; scanning and microchemistry of the leaves of V. guianensis. Tri stratified upper epidermis with intense cutinization and unistratified inferior epidermis was observed. The stomata found are paracytic and the trichomes arranged in rosettes are glandular, multicellular, stellate shape covered with cuticle, which were present on the abaxial surface. Parenchyma cells with idioblasts containing druses of calcium oxalate crystals were also found. The mesophyll is dorsiventral and the midrib is concave on the adaxial surface and convex on the opposite surface. The microchemical tests detected the presence of starch grains in the chlorophyll cells and phenolic compounds dispersed in the palisade tissue and abaxial surface. Alkaloids in the epidermis and in the sclerenchyma cells surrounding the vascular bundles and the midrib xylem, dispersed flavonoid in the palisade parenchyma and trichomes, fatty substances as content of the secretory ducts and reducing sugars in the palisade and epidermal cells were found. These anatomical features were fundamental in the identification and characterization of the species.
Jose Otavio Silva Junior Race et al.
International Journal of Pharmaceutical Sciences and Research , 2012,
Abstract: Vismia guianensis is a plant species of high occurrence in the Amazon and northeastern Brazil, which has been studied lately, because of its antimicrobial and anticancer properties. In order to make an herbal medicine, National Agency for Sanitary Surveillance of Brazil, recommends the production of a drug and plant extracts analysis report indicating: method, specifications and results obtained. The drug was characterized by particle size, amount of water and the total ash content; and plant extract through its density, pH and dry residue. The quantification of total anthraquinones and method validation was done by UV-VIS spectroscopy. The drug in this study produced a coarse powder whose determination of water is within the acceptable limits and the total ash content was 1.64%. The extractive solution showed a low pH, density of 0.89 mg/mL and 9.5% on yields from solids. HPLC found that the EtOAc fraction of the plant extract is consisted of phenolic compounds and anthraquinones. And the method of quantification of total anthraquinones, using emodin as external standard, was validated by UV-VIS spectroscopy at λ 290 nm, determining that in 1 g of extractive solution there are 42.85 mg of total anthraquinones. The results obtained served as reference for the quality control of drug and plant derivative of this species; and the validation of the quantification method showed a high performance.
Green Fertilization Enhances the Photosynthetic Performance and the Growth of Leguminous Trees for Restoration Plantation in Central Amazon  [PDF]
Roberto Kirmayr Jaquetti, José Francisco de Carvalho Gon?alves, Jo?o Baptista Silva Ferraz, Marciel J. Ferreira, Ulysses Moreira dos Santos Junior, Claudivan Feitosa de Lacerda
American Journal of Plant Sciences (AJPS) , 2014, DOI: 10.4236/ajps.2014.516264

The leguminous tree species Dipteryx odorata (Aubl.) Willd. and Inga edulis Mart. were grown in the field to reforest a degraded area. To investigate the photosynthetic responses and the initial growth of Amazonian forest species under fertilization, the study species were subjected to different treatments: T1 = unfertilized-control, T2 = chemical fertilization, T3 = green fertilization and T4 = green and chemical fertilization. D. odorata showed the highest absolute growth rates in height under treatments T4 (10.2 cm·month-1) and T2 (12.2 cm·month-1). I. edulis exhibited the best performance for this same parameter in T4 (23.0 cm·month-1). The highest photosynthesis values (Pn) for both D. odorata (13.1 μmol·m-2·s-1) and I. edulis (20.6 μ

Current indications of free gingival grafts
Daniela da Silva Feitosa,Mauro Pedrini Santamaria,Enilson Antonio Sallum,Francisco Humberto Nociti Junior
RGO : Revista Gaúcha de Odontologia , 2008,
Abstract: The aim of this report is to show three cases treated by the free gingival graft technique. Two patients presented multiple andisolated Miller’s Class II and III gingival recessions, localized in the anterior region of mandible. The third patient showed absence ofqueratinized gingiva on the buccal aspect of an osseointegrated implant. All patients received free gingival grafts, and the palate was the donor area. The patients were followed up to one year. After the healing period, all cases showed an increase of the queratinized gingival width and, in cases 1 and 2, a reduction in gingival recession. During follow-up period, no signs of gingival inflammation and bleeding on probing were seen. The patients maintained appropriate plaque control and were satisfied with the final esthetics. This report indicates that free gingival graft technique can be used for successful treatment of multiple and isolated gingival recessions, as well as to increase periimplantar queratinized gingival width.
Eduardo Porto Santos,Alexandre Sérgio Silva,Maria Jose de Carvalho Costa,James Silva Moura Junior
Biology of Sport , 2012,
Abstract: The effects of omega-3 (n-3) polyunsaturated fatty acid (PUFA) supplementation on the serum concentration of C-reactive protein (CRP) and activity of creatine kinase (CK) were investigated in military personnel. The concentrations of CRP and CK were used as inflammatory and muscle damage markers, respectively. Twenty subjects were divided into two groups and were given capsules containing either n-3 PUFA (SUP) (n=10) or placebo (PLA) (n=10) for four weeks. During the fourth week of supplementation, the subjects participated in a military boot camp that restricted both their calorie intake and rest, and increased their physical stress. Blood samples were taken in four instances: 1) pre-supplementation; 2) pre-camp; 3) during camp; 4) after camp. During the three weeks of supplementation and prior to boot camp, a significant reduction was observed in the serum concentration of CRP (50% only in group SUP (p=0.04). Significant increases in CK activity of 103.9% in SUP (p=0.0001) and 225.5% in PLA (p=0.004) after camp confirmed the strenuous nature of this procedure. Serum CRP increased during camp in both groups but the SUP group presented a significantly lower concentration of CRP at the end of boot camp in comparison to the PLA group (6.18 ± 2.6 U · L-1 and 8.6 ± 2.1 U · L-1 for SUP and PLA respectively, when p=0.04). These results suggest that supplementation with n-3 PUFA can exhibit a protective effect against the inflammatory process induced by a regimen of intense physical stress and food restriction.
Integration of Fogo Player and SAGE (Scalable Adaptive Graphics Environment) for 8K UHD Video Exhibition  [PDF]
Jane de Almeida, Guido Lemos de Souza Filho, Carlos Eduardo Coelho Freire Batista, Lucenildo Lins de Aquino Junior, Jose Ivan Vilarouca Filho, Manoel Silva Neto, Cicero Inacio da Silva, Leandro Ciuffo, Iara Machado, Clayton Reis da Silva
Journal of Computer and Communications (JCC) , 2014, DOI: 10.4236/jcc.2014.212006

After 4K, 8K UHD resolution can be considered the new challenge for film, visualization and television. Due to the dimension of 8K image, the remote micro and macro images are considered appropriate for visualization with scientific and educational purposes. This article describes the implementation of the 8K video plug-in to play UHD videos into the SAGE, a collaborative environment for the advancement of scientific research and education developed by EVL (Electronic Visualization Laboratory), upgrading its current resolution for video playing. It also presents the challenges of producing 8K content, the development of the code and introduces the features to view 8K ultra high definition videos in multiple tiles through the use of low cost computer clusters. The SAGE 8K video plug-in implementation was made possible because of the previous development of the Fogo Player, a system to run 4K and 8K content. The results were successfully presented at the CineGrid International Workshop 2013 in San Diego.

Fatores prognósticos em pacientes idosos admitidos em unidade de terapia intensiva
Stein, Francine de Cristo;Barros, Raffaelle Kasprowicz;Feitosa, Fernanda Seligman;Toledo, Diogo Oliveira;Silva Junior, Jo?o Manoel da;ísola, Alexandre Marini;Rezende, Ederlon;
Revista Brasileira de Terapia Intensiva , 2009, DOI: 10.1590/S0103-507X2009000300004
Abstract: currently, aging of the population is a widespread global phenomenon. therefore, the assessment of prognosis in elderly patients is needed. this study aims to identify risk factors in a population of elderly patients admitted in the intensive care unit methods: a prospective study in the intensive care unit of a general tertiary hospital was carried out for five months. patients with 65 years or more of age, who stayed in the intensive care unit for 24 hours or more were included and those at the-end-of-life, patients readmitted to intensive care unit during the same hospital stay were excluded. results: in this study 199 patients were involved, with a mean age of 75.4±6.8 years, and 58.8% were female. mortality was 57.3%. the mean apache ii, sofa, mods and katz index (assessment of daily activities) were respectively 20.0±5.8, 6.8±3.9, 2.4±1.9 and 5.3±1.6. most patients were postoperative 59.3% and 41.6% were under invasive mechanical ventilation. at regression analysis, the independent determinants of higher mortality were: older age (76.9±6.7 years death versus 73.3±6.5 years discharge, p<0.001, or=1.08, ci 95% 1.01-1. 16), the katz index (4.9±1.9 deaths versus 5.7±0.9 discharge, p=0.001, or=0.66, ci 95% 0.45-0.98), hyperglycemia (158.1±69.0 death versus 139.6±48.5 discharge p=0.041; or=1.02; ci 95% 1.01-1.03) and need for mechanical ventilation at admission to the intensive care unit (57.0% death versus 20.5% discharge p <0.001, or=3.57, ci 95% 1.24-10.3). conclusion: elderly patients admitted to the intensive care unit that have difficulties in performing daily activities, hyperglycemia and who are under invasive mechanical ventilation had a worse hospital prognosis.
Review of genitourinary tuberculosis with focus on end-stage renal disease
Lima, Neiberg A.;Vasconcelos, Carol C.;Filgueira, Pedro Henrique O.;Kretzmann, Meissa;Sindeaux, Ticiano A. S.;Feitosa Neto, Beni;Silva Junior, Geraldo B.;Daher, Elizabeth F.;
Revista do Instituto de Medicina Tropical de S?o Paulo , 2012, DOI: 10.1590/S0036-46652012000100011
Abstract: tuberculosis (tb) is a current public health problem, remaining the most common worldwide cause of mortality from infectious disease. recent studies indicate that genitourinary tb is the third most common form of extra-pulmonary disease. the diagnosis of renal tb can be hypothesized in a non-specific bacterial cystitis associated with a therapeutic failure or a urinalysis with a persistent leukocyturia in the absence of bacteriuria. we report on the case of a 33-year-old man who presented on admission end stage renal disease (esrd) secondary to renal tb and a past history of pulmonary tb with important radiologic findings. the diagnosis was based on clinical findings despite all cultures being negative. empiric treatment with tuberculostatic drugs was started and the patient became stable. he was discharged with no symptom, but without renal function recovery. he is on maintenance hemodialysis three times a week. tb is an important cause of kidney disease and can lead to irreversible renal function loss.
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