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Search Results: 1 - 10 of 532 matches for " Delphine Kerebel "
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A French multicenter randomised trial comparing two dose-regimens of prothrombin complex concentrates in urgent anticoagulation reversal
Delphine Kerebel, Luc-Marie Joly, Didier Honnart, Jeannot Schmidt, Damien Galanaud, Claude Negrier, Friedrich Kursten, Pierre Coriat, Lex206 Investigator Group
Critical Care , 2013, DOI: 10.1186/cc11923
Abstract: We performed a phase III, prospective, randomised, open-label study including patients with objectively diagnosed VKA-associated intracranial haemorrhage between November 2008 and April 2011 in 22 centres in France. Patients were randomised to receive 25 or 40 IU/kg of 4-factor PCC. The primary endpoint was the International Normalised Ratio (INR) 10 minutes after the end of 4-factor PCC infusion. Secondary endpoints were changes in coagulation factors, global clinical outcomes and incidence of adverse events (AEs).A total of 59 patients were randomised: 29 in the 25 IU/kg and 30 in the 40 IU/kg group. Baseline demographics and clinical characteristics were comparable between the groups. The mean INR was significantly reduced to 1.2 - and [lessthan or equal to] 1.5 in all patients of both groups - 10 min after 4-factor PCC infusion. The INR in the 40 IU/kg group was significantly lower than in the 25 IU/kg group 10 min (p=0.001), 1 hour (p=0.001) and 3 hours (p=0.02) after infusion. The 40 IU/kg dose was also effective in replacing coagulation factors such as PT (p=0.038), FII (p=0.001), FX (p<0.001), protein C (p=0.002) and protein S (0.043), 10 min after infusion. However, no differences were found in hematoma volume or global clinical outcomes between the groups. Incidence of death and thrombotic events was similar between the groups.Rapid infusion of both doses of 4-factor PCC achieved an INR of 1.5 or less in all patients with a lower INR observed in the 40 IU/kg group. No safety concerns were raised by the 40 IU/kg dose. Further trials are needed to evaluate the impact of the high dose of 4-factor PCC on functional outcomes and mortality. Trial registration: Eudra CT number 2007-000602-73.
Evaluation of early mini-bronchoalveolar lavage in the diagnosis of health care-associated pneumonia: a prospective study
Guillaume Lacroix, Bertrand Prunet, Julien Bordes, Nathalie Cabon-Asencio, Yves Asencio, Tiphaine Gaillard, Sandrine Pons, Erwan D'aranda, Delphine Kerebel, Eric Meaudre, Philippe Goutorbe
Critical Care , 2013, DOI: 10.1186/cc12501
Abstract: We prospectively included all patients presenting with HCAP in the emergency department. Blood cultures and fiberoptic bronchoscope-guided distal protected small volume bronchoalveolar lavage (FODP mini-BAL) were performed in each patient. Empiric antibiotic therapy was adapted microbiological findings were available. The primary objective was to assess that FODP mini-BAL is more efficient than blood cultures to identify pathogens with the ratio of identification between both techniques as principal criteria.We included 54 patients with HCAP. Pathogens were identified in 46.3% of cases using mini-BAL, and in 11.1% of cases using blood cultures (p < 0.01). When patient did not receive antibiotic therapy before the procedure, pathogens were identified in 72.6% of cases using mini-BAL, and in 9.5% of cases using blood cultures (p<0.01). We noted multidrug-resistant pathogens in 16% of cases. All bronchoscopic procedures could be performed in patients without complications.FODP mini-BAL was more efficient than blood cultures for identifying pathogens in patients presenting with HCAP. When bacteriological identification was obtained, antibiotic therapy was adapted in 100% of cases.
Vertical Heterogeneity of Genotypic Structure and Toxic Potential within Populations of the Harmful Cyanobacterium Microcystis aeruginosa  [PDF]
Benjamin Misson, Delphine Latour
Advances in Microbiology (AiM) , 2013, DOI: 10.4236/aim.2013.36A004
Abstract: We investigated the vertical variability of toxic potential (i.e. proportions of cells containing microcystin genes) and genotypic structure within different populations of Microcystis aeruginosa that developed in deep artificial reservoirs on the Loire River (France). We demonstrated that a great qualitative vertical heterogeneity could exist within a single bloom of this cyanobacterium in deep lakes. Indeed, we observed important vertical shifts of both toxic potential and genotypic structure, whatever the bloom magnitude. These variations occurred mainly within the euphotic zone and proved to occur independently from abundance vertical shifts. One of the most striking results of this study is that the genotypic structure of a population of M. aeruginosa was more variable between different depths sampled at a single site than between different sites of the same reservoir sampled on top of the water column. In the same way the proportion of potentially toxic cells was sometimes more variable vertically than horizontally. The occurrence of such vertical heterogeneity in three different blooms suggests that this could be a frequent pattern within populations of M. aeruginosa.
Palynological and Physicochemical Characterization of Honey in the Sudano-Guinean Zone of Cameroon  [PDF]
Dongock Nguemo Delphine, Tchoumboue Joseph
Food and Nutrition Sciences (FNS) , 2015, DOI: 10.4236/fns.2015.615140
Abstract: The palynological and physico-chemical characterization of honey was investigated in the Sudano- Guinean zone of Cameroon through the melissopalynology analysis. Results showed that honey with the dark amber color was the most represented. Sweet honey with less odour considered as pleasant highly predominate. The pH of honey is low and varies from 3.95 to 5.00; this ranking confirms the hypothesis that honey is from plant through visit of honeybees. The sugar content is very high ranging from 77.93% to 83.13%; the mean value is 78.90% and this value confirms that the honey is floral honey. The density value ranges from 1.39 to 1.43 and does not exceed the average standard (1.39 to 1.44 at 20). Water contents correspond to the standards norms. For free acidity, the highest value is 48.68 ± 0.28. There is a low positive correlation (r = 0.2) between free acidity and the pH of honey. Pollen analysis of honeys led to the identification of 41 pollen species belonging to 25 families. The highly represented families are Asteraceae and Myrtaceae. Two thirds of honey is monofloral and characteristics of three dominant species: Nymphaea maculata, Terminalia avicennioides and Syzygium guineense. The pollens of Syzygium guineense are present in all honey samples analysed.
Sweet Sweetback’s Baadasssss Song de Melvin Van Peebles (1971) : exégèse d’un film militant Sweet Sweetback’s Baadasssss Song by Melvin Van Peebles (1971): An Analysis of a Militant Movie
Delphine Letort
Revue LISA / LISA e-journal , 2009, DOI: 10.4000/lisa.790
Abstract: Sweet Sweetback’s Baadasssss Song represented a turning point in filmmaking when it was released in 1971. This article focuses on the interplay of the political and the aesthetic in a film that was conceived as a means of furthering change in the representation of African Americans. Not only did it support the emergence of black cinema by opening up filmmaking to black crews, but it also broached taboo subjects while depicting black sexuality (miscegenation) and police brutality. Melvin Van Peebles proposed a new heroic figure through the character of Sweetback, whose hypersexuality was to become a mercantile asset in Hollywood blaxploitation films. Nevertheless, the narrative’s reliance on a stereotypical Sweetback undermined its political message.
Houellebecq and the Novel as Site of Epistemic Rebellion
Delphine Grass
Opticon1826 , 2006, DOI: 10.5334/opt.010609
Abstract: Michel Houellebecq is a writer who cultivates an incongruous literary garden, where the necessity of describing contemporary objects as equipment for the manufacture of individuals can be said to precede his concern for literary conventions. This has been at the centre of much criticism formulated around Houellebecq’s novels. One book in particular by Eric Naulleau called Au Secour, Houellebecq Revient! attacks his novels on the grounds that their success relies on his charming the reader by using recognisable elements of everyday life and incorporating them in the novels, in such a way that they could no longer be distinguished from the world of everyday life.
Les femmes Prix de Rome de Peinture et de Sculpture (1911-1968)
Delphine Sicurani
Genre & Histoire , 2009,
Abstract: Au lendemain de la révolution sexuelle, l'historienne de l'art Linda Nochlin baptise l'année 1971 par cette per ante et insolite question qui, source de nombreuses polémiques, a pour moindre mérite d'ouvrir un passionné et passionnant débat : Pourquoi n'y a-t-il pas eu de grands artistes femmes ? . Un bien curieux titre pour un article, dont le ma tre mot est incontestablement la provocation. Finalement le temps, juge impartial et intransigeant, légitimera l'intérêt de cette interrogatio...
Alexandrescu & Théis (éds.), Nature et surnaturel. Philosophies de la nature et métaphysique aux XVIe-XVIIIe siècles (2010)
Delphine Bellis
Studium : Tijdschrift voor Wetenschaps- en Universiteits-Geschiedenis , 2011,
Unsupervised learning of morphological families: comparison of methods and multilingual aspects Apprentissage non supervise de familles morphologiques : comparaison de me thodes et aspects multilingues
Delphine Bernhard
Traitement Automatique des Langues , 2011,
Abstract: This article describes MorphoClust and MorphoNet, two methods for the unsupervised acquisition of morphological families. MorphoClust builds families by iterative conflations, similarly to hierchical clustering methods. The MorphoNet method relies on community detection in lexical networks. The nodes of these networks stand for words while edges represent morphological transformation rules which are automatically acquired based on graphical similarities between words. The two methods are applied to a German-English bilingual lexicon, both in isolation and in combination. We evaluate the results using the CELEX lexical database.
Gender, migration and agency: developing a “hauntology” of new becomings in Shauna Singh Baldwin’s Devika and in Ginu Kamani’s Just between Indians = Gênero, migra o e agência: o desenvolvimento de uma ‘hauntologia’ de novas transforma es em Devika de Shauna Singh Baldwin e Just between Indians de Ginu Kamani
Delphine Munos
Acta Scientiarum : Language and Culture , 2011,
Abstract: In recent short stories written by diasporic Indian women writers, changes in terms of location or national identity are generally depicted as providing significant opportunities for Indian women to challenge and revise culturally-inscribed gender roles. In two collections of short stories written respectively by Ginu Kamani and Shauna Singh Baldwin, Junglee Girl and English Lessons and Other Stories, not only are ghosts employed to rupture boundaries between the living and the dead, but they also represent enabling presences which authorize female voices by resurrecting stories of women that have been silenced or forgotten. In these two books, the emergence of the archaic is recurrently tinged with liberating undertones since it opens up new spaces for identity by countering gendered expectations of ‘acceptable’ behaviour and by constructing alternative realities. My essay will therefore focus on the central metaphors of female ghosts and doubles as transitional figures through which women in transit empower themselves. My aim is to show how culturallydisplaced women appropriate the uncanny so as to engender new identities and assert the value of individual female experience. In these haunted narratives, I will contend, women move from a ghostly time of repetition to a ‘hauntology’ of new becomings. Nos contos contemporaneos de escritoras indianas diaspóricas, asmudan as em loca o ou identidade nacional s o em geral descritas como fatores que proporcionam oportunidades significativas para que as mulheres indianas desafiem e revisem os papeis de gênero culturalmente inscritos. Em duas cole es de contos, Junglee Girl e English Lessons and Other Stories, escritos respectivamente por Ginu Kamani e Shauna Singh Baldwin, os fantasmas s o introduzidos n o apenas para quebrar as fronteiras entre os vivos e os mortos, mas para representarem ocasi es que autorizam as vozes femininas pararessuscitar histórias de vida feminina que foram silenciadas ou suprimidas. A emergência de costumes arcaicos é constantemente tingida por contrapontos libertadores já que se abrem novos espa os de identidade por oporem expectativas de gênero caracterizadas por‘comportamentos aceitáveis’ e por construírem realidades alternativas. Focalizam-se as metáforas de fantasmas femininos e personagens duplas como figuras transitórias através das quais as mulheres diaspóricas assumem o poder. Verifica-se como as mulheresculturalmente deslocadas se apropriam do estranhamento para construírem novas identidades e afirmarem o valor da experiência feminina. Nestas narrativas de ‘fantasmas’ as
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