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Search Results: 1 - 6 of 6 matches for " Darlin "
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Reverse Phase High Pressure Liquid Chromatographic Determination of Rifampin Quinone and Hydrazone in Anti-tuberculosis Fixed-Dose Formulations Containing Sodium Ascorbate as Anti-oxidant
P Umapathi, J Ayyappan, Darlin Quine
Tropical Journal of Pharmaceutical Research , 2010,
Abstract: Purpose: To establish the method for the analysis of rifampin quinone and hydrazone in fixeddose combination tablets (FDC) containing rifampicin with or without sodium ascorbate as an additive. Methods: The International Pharmacopoeial (IP) method for the estimation of rifampin quinone in FDC was modified. The extraction solvent (methanol/buffer mixture) of the IP method was replaced with ethyl acetate, in order to stabilize rifampin quinone in sample solutions of FDC containing sodium ascorbate as an ingredient. Results: Rifampin quinone in FDC samples containing sodium ascorbate, which is not detectable in the IP method, was found to be 1.15 % (4-FDC), 1.52 % (3-FDC) and 1.60 % (2-FDC) using the modified method. Recovery of rifampin quinone in spiked samples of FDCs was practically nil in IP method whereas the recovery was 99.95%, 99.39 and 99.02 % for 4–FDC, 3-FDC and 2-FDC, respectively. Conclusion: This modified method was suitable for the determination of rifampin quinone in fixed-dose formulations of rifampin both in the presence and absence of sodium ascorbate. The method is specific, precise, accurate, robust, rugged and gives a linear response for the quantitative estimation of rifampin quinone and hydrazone in fixed-dose combination tablets containing rifampin.
Establecimiento de un sistema de vigilancia científico-tecnológica
Salgado Batista,Darlin; Guzmán Sánchez,María Victoria; Carrillo Calvet,Humberto;
ACIMED , 2003,
Abstract: in spite of considering the technological-scientific surveillance as a determining activities in organizations a little is known and practiced. sometimes it is confused with monitoring, technical prospective, benchmarking, etc. nevertheless, the technological-scientific surveillance show a methodology and features that distinguish it from the other refered activities. the metodology to outline a surveillance system is exposed. the experimental french pattern afnor xp x 50-053-fre only one available for this service. a proposal for the establishment of a technological scientific surveillance system for alimentary industry research center (airc) is provided.
Establecimiento de un sistema de vigilancia científico-tecnológica
Darlin Salgado Batista,María Victoria Guzmán Sánchez,Humberto Carrillo Calvet
ACIMED , 2003,
Abstract: A pesar de considerarse la vigilancia científico- tecnológica como una actividad determinante en las organizaciones, se conoce y se practica poco. A menudo, se confunde con el monitoreo, la prospectiva tecnológica, el benchmarking, etcétera. Sin embargo, la vigilancia científico- tecnológica presenta una metodología y unas especificidades que la diferencian de las demás. actividades referidas. Se expone, paso a paso, la metodología a seguir para dise ar un sistema de vigilancia como el mencionado. Para ello, se utilizó la norma experimental francesa AFNOR XP X 50-053-FRE, la única existente para la creación de esta clase de servicio. Se realiza una propuesta para el establecimiento de un sistema de vigilancia científica y tecnológica para el Instituto de Investigaciones de la Industria Alimentaria (IIIA). In spite of considering the technological-scientific surveillance as a determining activities in organizations a little is known and practiced. Sometimes it is confused with monitoring, technical prospective, benchmarking, etc. Nevertheless, the technological-scientific surveillance show a methodology and features that distinguish it from the other refered activities. The metodology to outline a surveillance system is exposed. The experimental french pattern AFNOR XP X 50-053-FRE only one available for this service. A proposal for the establishment of a technological scientific surveillance system for Alimentary Industry Research Center (AIRC) is provided.
La investigación en Cuba sobre evaluación de bibliotecas The investigation in Cuba about libraries evaluation
Darlin Salgado Batista,María Victoria Guzmán Sánchez,Yaidelyn Macías Rivero
ACIMED , 2012,
Abstract: Hay varias razones por las que es importante para las bibliotecas evaluar los procesos de sus organizaciones, los recursos y servicios. Conocer el estado del arte en un tema es parte del caudal del conocimiento que sobre la disciplina debe dominar un profesional de la información. Por eso, este trabajo se ha trazado como objetivo revisar y analizar la investigación en Cuba sobre evaluación de bibliotecas. Para lograrlo fue necesario crear una base de datos a partir de diversas fuentes como los trabajos presentados en los Congresos INFO′s y los publicados en la revista Acimed. Los resultados han permitido identificar las características de la evaluación bibliotecaria en Cuba y su comportamiento por tipos de bibliotecas. Se define, además, la evaluación bibliotecaria como un proceso integrador, vinculado a la gestión de la calidad y se plantean una serie de consideraciones sobre las contribuciones hechas en Cuba sobre el tema. There are several important reasons for the libraries to evaluate the processes of their organizations, the resources and services. To know the state of the art in a topic, it is part of the flow of the knowledge that it has more than enough of the discipline, a professional of the information it should dominate. For that reason, this paper aim was to analyze the investigation about libraries evaluation in Cuba. For it was necessary to create a database (BD) starting from diverse sources like the papers presented in the Congresses INFO′s and in the magazine ACIMED. The results have allowed us to identify the characteristics of the librarian evaluation in Cuba and the indicators used to make the evaluation in different kinds of libraries. Is defined, also, the librarian evaluation like an integrative process, linked to the management of the quality and bring up a series of considerations on the parts made in Cuba on the subject.
La evaluación de las bibliotecas de instituciones cubanas de investigación en biotecnología
Salgado-Batista, Darlin,Guzmán-Sánchez, Maria Victoria,Macías-Rivero, Yaidelyn
Revista Espa?ola de Documentación Científica , 2012,
Abstract: The evaluation of library performance and its relation to the effective functioning of R&D activities is unquestionable. Although there has been broad coverage of indicators for library evaluation, little has been produced about libraries attached to centres of high technology, such as biotechnology. The aim of this paper is to analyse the current situation of performance evaluations in 22 libraries of Cuban biotechnology research centres. The data introduced were gathered from a survey inquiring in to the use by library staff of this kind of study and the importance attached to it. The outputs of this paper could contribute to the development of performance indicators for libraries belonging to R&D centres. The outcome will also be useful for furthering comparative studies among different types of libraries. La evaluación del desempe o de las Bibliotecas y su vínculo con el buen funcionamiento de las actividades de Investigación y Desarrollo (I+D) es incuestionable. Aunque los indicadores para la evaluación de bibliotecas han sido ampliamente aborda dos, se ha hecho poco para las bibliotecas vinculadas a los centros de alta tecnología, tales como los dedicados a la biotecnología. El objetivo de este trabajo es analizar la situación actual de la evaluación del desempe o en 22 bibliotecas pertenecientes a instituciones cubanas de investigación en biotecnología. Los elementos aquí presentados fueron recogidos a partir de la aplicación de una encuesta, en la cual se indagó sobre el uso y la importancia que le confiere el personal bibliotecario a este tipo de estudio. Los resultados de este trabajo pueden contribuir con el desarrollo de indicadores de desempe o para las bibliotecas pertenecientes a centros de I+D. Servirán, también, para enriquecer estudios comparativos entre diferentes tipos de bibliotecas.
Anthelminthic Activity of Cansjera rheedii J. Gmelin (Opiliaceae)
V.M. Mounnissamy,S. Kavimani,V. Balu,S. Darlin Quine
Journal of Biological Sciences , 2008,
Abstract: The ethanol, water and chloroform extracts of the aerial parts of Cansjera rheedii J. Gmelin (Opiliaceae) were investigated for activity against Indian earthworms Pheretima posthuma. Various concentrations (5-40 mg mL-1) of each extract were tested, which involved determination of time of paralysis and time of death of the worms. All three extracts exhibited considerable anthelminthic activity. All the extracts (i.e., aqueous, chloroform and ethanol) at the tested dose (5-40 mg mL-1) level produced significant activity (p < 0.001) when compared with piperazine citrate (15 mg mL-1) and albendazole (20 mg mL-1) which were included as standard reference and normal saline as control. The present study indicates the potential usefulness of Cansjera rheedii aerial parts as anthelminthic activity.
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