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Search Results: 1 - 10 of 7074 matches for " Daniela Palomba "
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Posttraumatic and Depressive Symptoms in Victims of Occupational Accidents
Giulia Buodo,Caterina Novara,Marta Ghisi,Daniela Palomba
Depression Research and Treatment , 2012, DOI: 10.1155/2012/184572
Abstract: The present descriptive study was aimed at evaluating posttraumatic and depressive symptoms and their cooccurrence, in a sample of victims of workplace accidents. Also, posttraumatic negative cognitions were assessed. Eighty-five injured workers were evaluated, using the PTSD Symptom Scale, the Beck Depression Inventory II, and the posttraumatic Cognitions Inventory. 49.4% of injured workers reported both depressive and posttraumatic symptoms of clinical relevance. 20% only reported posttraumatic, but not depressive, symptoms, and 30.6% did not report either type of symptoms. The group with both posttraumatic and depressive symptoms displayed greater symptom severity and more negative cognitions about the self and about the world than the other two groups. The obtained findings indicate that workplace accidents can have a major impact upon the mental health of victims. Early interventions should be focused not only on the prevention or reduction of posttraumatic and depressive symptoms but also on restructuring specific maladaptive trauma-related cognitions. 1. Introduction It has been consistently demonstrated that in some individuals exposure to traumatic events is followed by full or partial posttraumatic stress disorder (PTSD; see [1]). However, in a substantial proportion of cases PTSD is not the only psychological disorder occurring after a traumatic event. Indeed, survey studies report that lifetime comorbidity of PTSD with at least one other psychiatric disorder is found in about 70–80% of affected individuals [2, 3]. Among axis I disorders, major depression has the highest comorbidity rate with PTSD, with 30–50% of individuals affected by PTSD showing significant depressive symptoms [2, 4]. In order to explain the frequent cooccurrence of PTSD and depression, different hypotheses have been proposed. The possibility of a common underlying vulnerability to both disorders is suggested by the apparent bidirectional relationship between PTSD and depression, where preexisting depression can increase an individual’s susceptibility to develop PTSD after a trauma and, on the other hand, PTSD can increase the onset probability of depression [2, 5–7]. The hypothesis of a shared diathesis is further strengthened by data showing an increased risk for major depression in individuals with PTSD, but not in trauma-exposed individuals without PTSD [1]. Therefore, these findings suggest that exposure to traumatic events in itself does not increase the risk for developing depression independent of PTSD effects. Although the cooccurrence of PTSD and depression
Detectability of Gravitational Radiation from Prompt and Delayed Star Collapse to a Black Hole
Cristiano Palomba
Physics , 2000,
Abstract: We consider the emission of gravitational waves in the two proposed models for the collapse of a massive star to a black hole: the prompt collapse, in which nearly all the star collapses to a black hole in a dynamical time scale, and the delayed collapse, in which a light black hole, or a neutron star, which subsequently accretes matter, forms due to the fall-back achieving, in the neutron star case, the critical mass for black hole formation. Recent simulations strongly support this last scenario. We show that, due to the slowness of fall-back, in the delayed collapse the main burst of gravitational radiation is emitted depending on the parameters, mass and angular momentum, of the initial, light, black hole. We estimate, under different assumptions, the detectability of the emitted gravitational waves showing that such kind of collapse is not particularly suited for detection by forthcoming interferometric detectors. Detectors with high sensitivity at frequencies greater than ~4-5 kHz would be well suited for this kind of sources. We calculate also the final mass distribution function of single black holes.
Pulsars ellipticity revised
Cristiano Palomba
Physics , 1999,
Abstract: We derive new upper limits on the ellipticity of pulsars whose braking index has been measured, more tightening than those usually given, assuming that both a gravitational torque and an electromagnetic one act on them. We show that the measured braking indexes of pulsars are recovered in this model. We consider the electromagnetic torque both constant and varying with time. At the same time constraints on the pulsars initial period and on the amplitude of the gravitational waves emitted are obtained.
Role of BRCA2 mutation status on overall survival among breast cancer patients from Sardinia
Mario Budroni, Rosaria Cesaraccio, Vincenzo Coviello, Ornelia Sechi, Daniela Pirino, Antonio Cossu, Francesco Tanda, Marina Pisano, Grazia Palomba, Giuseppe Palmieri
BMC Cancer , 2009, DOI: 10.1186/1471-2407-9-62
Abstract: Among incident cases during the period 1997–2002, a total of 512 breast cancer patients gave their consent to undergo BRCA mutation screening by DHPLC analysis and automated DNA sequencing. The Hakulinen, Kaplan-Meier, and Cox regression methods were used for both relative survival assessment and statistical analysis.In our series, patients carrying a germline mutation in coding regions and splice boundaries of BRCA1 and BRCA2 genes were 48/512 (9%). Effect on overall survival was evaluated taking into consideration BRCA2 carriers, who represented the vast majority (44/48; 92%) of mutation-positive patients. A lower breast cancer-specific overall survival rate was observed in BRCA2 mutation carriers after the first two years from diagnosis. However, survival rates were similar in both groups after five years from diagnosis. No significant difference was found for age of onset, disease stage, and primary tumour histopathology between the two subsets.In Sardinian breast cancer population, BRCA2 was the most affected gene and the effects of BRCA2 germline mutations on patients' survival were demonstrated to vary within the first two years from diagnosis. After a longer follow-up observation, breast cancer-specific rates of death were instead similar for BRCA2 mutation carriers and non-carriers.The breast cancer is a complex disease with high biological heterogeneity and wide spectrum of responsiveness to different treatments. The well-established prognostic factors currently used into the management of patients with breast carcinoma include the disease stage (which takes into account tumour size, axillary lymph node involvement, and distant tumour dissemination) as well as the histological type, the degree of differentiation (tumour grade), the proliferation index, and the receptor status [estrogen receptor (ER), progesterone receptor (PR), and, recently, HER2] of the primary tumours [1]. Among them, the expression levels of hormone receptors seem to better predict the
Pain-related somatosensory evoked potentials and functional brain magnetic resonance in the evaluation of neurologic recovery after cardiac arrest: a case study of three patients
Paolo Zanatta, Simone Messerotti Benvenuti, Fabrizio Baldanzi, Matteo Bendini, Marsilio Saccavini, Wadih Tamari, Daniela Palomba, Enrico Bosco
Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine , 2012, DOI: 10.1186/1757-7241-20-22
Abstract: Early and accurate prognostic assessment of neurological functional outcomes in comatose patients after cardiac arrest is a relevant medical, ethical, and economic issue. It has been shown that beyond the Glasgow Coma Scale (GCS), a patient's pupil light reactivity, corneal reflexes, myoclonus status epilepticus, and serum neuron-specific enolase, short latency somatosensory-evoked potentials (SEPs) (N20/P25) improve the accuracy of neurological prognosis in comatose patients after cardiac arrest [1]. SEPs have shown high sensitivity and specificity in predicting poor outcomes. Indeed, that the bilateral disappearance of cortical N20/P25 is well-established to be associated with adverse outcomes such as death or survival in a vegetative state. Nonetheless, the presence of N20/P25 may not be sensitive enough to predict a good neurological outcome [2]. In fact, only the event-related evoked potentials (i.e., mismatched negativity and novelty P300), middle latency cortical somatosensory-evoked potentials (MLCEPs), and reactivity electroencephalogram (EEG) background have been associated with a favourable neurological prognosis [3-7].In recent years, brain functional neuroimaging has been used in order to clarify the diagnosis of the vegetative state, suggesting that brain activation imaging may reflect awareness and/or cognition and provide reliable prognostic information [8,9]. However, given that this methodology is based on imagery and communication task paradigms, this approach is only feasible in the chronic phase of consciousness disorders. Moreover, studies using positron emission tomography have shown that minimally conscious state patients, compared to vegetative state patients, may show brain processing activation elicited by noxious electrical stimulation of the median nerves similar to that seen in healthy controls, suggesting a possible cortical processing of pain [10-12]. However, the intensity of electrical stimuli applied in vegetative patients (i.e., 1
Evaluating the Impact of Different Sequence Databases on Metaproteome Analysis: Insights from a Lab-Assembled Microbial Mixture
Alessandro Tanca, Antonio Palomba, Massimo Deligios, Tiziana Cubeddu, Cristina Fraumene, Grazia Biosa, Daniela Pagnozzi, Maria Filippa Addis, Sergio Uzzau
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0082981
Abstract: Metaproteomics enables the investigation of the protein repertoire expressed by complex microbial communities. However, to unleash its full potential, refinements in bioinformatic approaches for data analysis are still needed. In this context, sequence databases selection represents a major challenge. This work assessed the impact of different databases in metaproteomic investigations by using a mock microbial mixture including nine diverse bacterial and eukaryotic species, which was subjected to shotgun metaproteomic analysis. Then, both the microbial mixture and the single microorganisms were subjected to next generation sequencing to obtain experimental metagenomic- and genomic-derived databases, which were used along with public databases (namely, NCBI, UniProtKB/SwissProt and UniProtKB/TrEMBL, parsed at different taxonomic levels) to analyze the metaproteomic dataset. First, a quantitative comparison in terms of number and overlap of peptide identifications was carried out among all databases. As a result, only 35% of peptides were common to all database classes; moreover, genus/species-specific databases provided up to 17% more identifications compared to databases with generic taxonomy, while the metagenomic database enabled a slight increment in respect to public databases. Then, database behavior in terms of false discovery rate and peptide degeneracy was critically evaluated. Public databases with generic taxonomy exhibited a markedly different trend compared to the counterparts. Finally, the reliability of taxonomic attribution according to the lowest common ancestor approach (using MEGAN and Unipept software) was assessed. The level of misassignments varied among the different databases, and specific thresholds based on the number of taxon-specific peptides were established to minimize false positives. This study confirms that database selection has a significant impact in metaproteomics, and provides critical indications for improving depth and reliability of metaproteomic results. Specifically, the use of iterative searches and of suitable filters for taxonomic assignments is proposed with the aim of increasing coverage and trustworthiness of metaproteomic data.
Psychological Distress and Post-Traumatic Symptoms Following Occupational Accidents
Marta Ghisi,Caterina Novara,Giulia Buodo,Matthew O. Kimble,Simona Scozzari,Arianna Di Natale,Ezio Sanavio,Daniela Palomba
Behavioral Sciences , 2013, DOI: 10.3390/bs3040587
Abstract: Depression and post-traumatic stress disorder frequently occur as a consequence of occupational accidents. To date, research has been primarily focused on high-risk workers, such as police officers or firefighters, and has rarely considered individuals whose occupational environment involves the risk of severe, but not necessarily life-threatening, injury. Therefore, the present study was aimed at assessing the psychological consequences of accidents occurring in several occupational settings (e.g., construction and industry). Thirty-eight victims of occupational accidents (injured workers) and 38 gender-, age-, and years of education-matched workers who never experienced a work accident (control group) were recruited. All participants underwent a semi-structured interview administered by a trained psychologist, and then were requested to fill in the questionnaires. Injured workers reported more severe anxious, post-traumatic and depressive symptoms, and poorer coping skills, as compared to controls. In the injured group low levels of resilience predicted post-traumatic symptomatology, whereas the degree of physical injury and the length of time since the accident did not play a predictive role. The results suggest that occupational accidents may result in a disabling psychopathological condition, and that a brief psychological evaluation should be included in the assessment of seriously injured workers.
Quella certa età: l’invecchiare delle donne
Rossella Palomba,Nicoletta Signoretti
Storia delle Donne , 2006,
Abstract: In the article we analysed attitudes of women over 60 towards the last phase of life and the changes perceived in their body and in their social role as compared to when they were young, their expectations towards the family, work ,voluntary work, and hobbies. A survey of 2344 women carried out by IRPPS is used. We also analysed if the image of older women hold by Italian society has changed because the attitudes of the “others” influence the way we live the ageing process and its changes. For this purpose we will use recent studies on TV advertisements and the image of older women they convey.
Psicopatologia Psychopatology
Guido Arturo Palomba
Jornal Brasileiro de Psiquiatria , 2008, DOI: 10.1590/s0047-20852008000100014
Abstract:
Evaluation of homeopathic treatments in early lactation in buffalo cows and neonatal mortality in buffalo calf  [PDF]
Fiorella Sarubbi, Rodolfo Baculo, Raffaele Palomba, Giuseppe Auriemma
Open Journal of Animal Sciences (OJAS) , 2012, DOI: 10.4236/ojas.2012.23027
Abstract: The trial was conducted on thirty buffalo cows subdivided in three groups. In the immediate pre-calving, 2.5 ml of Echinacea purpurea were orally administered to the first group (A) and, after calving, Nux vomica, Chelidonium and Lycopodium were administered at 7 days intervals. The second group (B) was only subjected to the post-calving treatment, while the third group (C) represented the control group. Immediately after calving two groups of calves were formed. The first group received 5 granules of Pyrogenium in the first days of life and then for 10 days the 0.5 ml of E. purpurea. The second group did not receive any remedy. Before the calving, in conventional farm twenty buffalo cows (D group) were vaccinated. Remedies administration did not affect milk protein content, milk lipid contents and the achievement of the lactation peak. Blood samples showed that total protein, albumin and globulin levels were lower in group A, compared to groups B and C. Cholesterol and urea were lower in the treated groups than in the control. We therefore conclude that the use of homeopathic remedies are a chance to improve animal welfare and their productive characteristics.
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