oalib

Publish in OALib Journal

ISSN: 2333-9721

APC: Only $99

Submit

Any time

2019 ( 182 )

2018 ( 322 )

2017 ( 305 )

2016 ( 408 )

Custom range...

Search Results: 1 - 10 of 234071 matches for " Daniela C. Fernandes "
All listed articles are free for downloading (OA Articles)
Page 1 /234071
Display every page Item
Baru almonds from different regions of the Brazilian Savanna: Implications on physical and nutritional characteristics  [PDF]
Ludmila P. Czeder, Daniela C. Fernandes, Jullyana B. Freitas, Maria Margareth V. Naves
Agricultural Sciences (AS) , 2012, DOI: 10.4236/as.2012.35090
Abstract: While some reports show that physical characteristics of the baru fruits (Dipteryx alata Vog.) differ within and among the Brazilian Savanna regions, a study shows that there are differences in the nutritional composition of baru almonds from different trees from the same Savanna area. It is unknown, however, whether the Savanna’s region influences the nutritional quality of this native almond. Thus, we evaluated the influence of East, Southeast and West regions of the Brazilian Savanna on physical characteristics, nutrient composition and protein quality of the baru almond. Chemical composition and amino acid profile were analyzed, and Amino Acid Score (AAS), Net Protein Ratio (NPR), and Protein Digestibility–Corrected Amino Acid Score (PDCAAS) were estimated. The physical characteristics significantly differed within but not among regions. The protein (310 g kg-1), lipid (410 g·kg-1), fiber (120 g·kg-1) and calcium (1,300 mg·kg-1) contents of baru almonds were high, with significant differences among regions for insoluble fiber content (94.3 - 128.3 g·kg-1) and amino acid profile (AAS = 77% - 89%). The relative NPR (RNPR) values were similar among regions (mean value of RNPR = 71%), and the PDCAAS values ranged from 65 to 73%. The region of the Brazilian Savanna influences the fiber and amino acid profiles, but not the total content of nutrients, the protein quality and the physical characteristics of the native baru almonds. The baru almond is a potential food as source of complementary protein for healthy diets and as a nutritious raw material for various food systems.
Edible Seeds and Nuts Grown in Brazil as Sources of Protein for Human Nutrition  [PDF]
Jullyana B. Freitas, Daniela C. Fernandes, Ludmila P. Czeder, Jean Carlos R. Lima, Amanda G. O. Sousa, Maria Margareth V. Naves
Food and Nutrition Sciences (FNS) , 2012, DOI: 10.4236/fns.2012.36114
Abstract: Edible seeds and nuts can contribute to an adequate intake of protein, particularly in vegetable-based diets. However, there are relatively few reports with insufficient data regarding the protein quality of these foods, especially of edible seeds and nuts from Brazil. The aim of this study was to investigate the chemical composition and in vivo protein quality of two edible seeds (baru almond and peanut) and two nuts (Brazil nut and cashew nut) grown in Brazil. The proximate composition and the amino acid profile were analyzed. The true protein digestibility and the protein quality of these foods were evaluated by bioassay with male weanling Wistar rats over a period of 14 days, and the Protein Digestibility Corrected Amino Acid Score (PDCAAS) was estimated. Edible seeds and nuts presented high contents of proteins (16.3 to 32.3 g/100g), lipids (42.7 to 57.9 g/100g) and dietary fibers (6.5 to 14.3 g/100g). Lysine was found to be the limiting amino acid in baru almond, peanut and Brazil nut, which had amino acid scores ranging from 71% to 76%. Cashew nut had no limiting amino acid. These foods showed high protein digestibility (around 90%) except for baru almond (75%), and their PDCAAS values varied significantly (57%, for baru almond, and 90%, for cashew nut). The edible seeds and nuts grown in Brazil provide a high density of energy and nutrients and they can be used as complementary sources of proteins.
Behcet’s disease and IgA nephropathy: report of this association in a patient from Brazil and literature review Enfermedad de Behcet y nefropatía por IgA: reporte de tal asociación en un paciente de Brasil y revisión de literatura
Paula FCBC Fernandes,Geraldo B Silva Júnior,Fernando AS Barros,Daniela C Sousa
Investigación Clínica , 2006,
Abstract: Behcet’s disease (BD) is associated with renal involvement in about one-third of the cases and a variety of renal lesions have been reported. A 27-year-old man presented a history of recurrent oral and genital ulcers, associated with pseudofoliculitis and arthritis in his left knee. The first laboratory tests revealed: urea = 53mg/dL, creatinine = 1.8mg/dL. The urinalysis showed leukocyturia. Initial treatment with ceftriaxone, thalidomide and prednisone was instituted. He became clinically stable, with normal renal function, but presenting hematuria and proteinuria. One year later the patient presented dark urine. The new laboratory tests showed urea = 58mg/dL, creatinine = 1.4mg/dL, and mild proteinuria (500-1000mg/24h). Two years later the proteinuria was 2230mg/day. The renal biopsy showed one glomerulus with severe glomerular sclerosis, mild tubular atrophy, mild interstitial fibrosis and thickening of arterial walls. Treatment with captopril was started to decrease proteinuria. Two years later, the patient presented creatinine = 1.7mg/dL and proteinuria = 2509mg/day. A new renal biopsy evidenced proliferative crescentic glomerulonephritis, with diffuse granullary deposits of IgA, IgM and C3. It was instituted pulsotherapy with metilprednisolone, monthly endovenous cyclophosphamide and maintenance prednisone. The patient became clinically stable, with creatinine of 1.3mg/dL and proteinuria of 500mg/day. BD could be one of the various causes of secondary IgA nephritis. It is important to periodically perform renal function evaluation in patients with BD, through urinalysis and measurement of serum creatinine and its clearance, in order to detect any abnormality and provide an early adequate treatment. La enfermedad de Behcet (EB) está asociada a da o renal en cerca de un tercio de los casos y una variedad de lesiones renales han sido descritas. Un hombre de 27 a os presentaba historia de ulceraciones orales y genitales, en asociación con pseudofoliculitis y artritis en su rodilla izquierda. Los primeros exámenes evidenciaban urea = 53mg/dL, creatinina = 1,8mg/dL. El análisis de orina presentaba leucocituria. El tratamiento inicial fue ceftriaxone, talidomida y prednisona. El enfermo se quedó clínicamente estable, con función renal normal, pero presentando hematuria y proteinuria. Pasado un a o, su orina resultó oscura. Nuevos exámenes mostraban urea = 58mg/dL, creatinina = 1,4mg/dL y proteinuria (500-1000mg/día). Dos a os después la proteinuria aumentó para 2230mg/día. La biopsia renal mostraba uno glomérulo con esclerosis severa, atrofia tubular bl
The Role of Heme and Reactive Oxygen Species in Proliferation and Survival of Trypanosoma cruzi
Marcia Cristina Paes,Daniela Cosentino-Gomes,Cíntia Fernandes de Souza,Natália Pereira de Almeida Nogueira,José Roberto Meyer-Fernandes
Journal of Parasitology Research , 2011, DOI: 10.1155/2011/174614
Abstract: Trypanosoma cruzi, the protozoan responsible for Chagas disease, has a complex life cycle comprehending two distinct hosts and a series of morphological and functional transformations. Hemoglobin degradation inside the insect vector releases high amounts of heme, and this molecule is known to exert a number of physiological functions. Moreover, the absence of its complete biosynthetic pathway in T. cruzi indicates heme as an essential molecule for this trypanosomatid survival. Within the hosts, T. cruzi has to cope with sudden environmental changes especially in the redox status and heme is able to increase the basal production of reactive oxygen species (ROS) which can be also produced as byproducts of the parasite aerobic metabolism. In this regard, ROS sensing is likely to be an important mechanism for the adaptation and interaction of these organisms with their hosts. In this paper we discuss the main features of heme and ROS susceptibility in T. cruzi biology. 1. Trypanosoma cruzi and Its Biological Cycle Trypanosoma cruzi comprises a complex group of parasite populations circulating among humans, vectors, reservoirs, and wild and domestic animals [1]. This parasite is the causative agent of Chagas disease or American trypanosomiasis [2] and is transmitted through triatomine vectors, which are blood-sucking insects, when they feed on the vertebrate host. After an insect feeds on the blood of an infected vertebrate, the development cycle of the parasite begins in the intestinal tract of triatomines. In the anterior midgut, most blood trypomastigotes transform into epimastigotes a few hours after ingestion. Some epimastigotes multiply by longitudinal binary fission, and in the insect rectum, a new differentiation occurs (metacyclogenesis process) in which epimastigotes are transformed into metacyclic trypomastigotes. These metacyclic trypomastigotes (highly infectious) are shed in feces and reach the bloodstream of a new vertebrate host after this host scratches an insect bite. The organisms penetrate the mucosa where there are many macrophages; after intense multiplication in the host cell in the form of amastigotes, they transform into trypomastigotes again, returning to the vertebrate circulation and completing the cycle [3]. These series of morphological and biochemical transformations in the life cycle may occur in response to external stimuli [4]. Recently, reactive oxygen species (ROS) and heme have been hypothesized to be important signaling molecules. In this way, protozoan parasites, which are specifically located in places where these
Inventário de Depress?o de Beck - BDI: valida??o fatorial para mulheres com cancer
Gandini, Rita de Cássia;Martins, Maria do Carmo Fernandes;Ribeiro, Marjorie de Paula;Santos, Daniela Torres Gon?alves;
Psico-USF , 2007, DOI: 10.1590/S1413-82712007000100004
Abstract: this study refers to the factor analysis of the beck depression inventory - bdi in a population composed by 208 women with cancer. the extraction method was principal components and the rotation procedure was oblimin. the bdi factorial analysis was done through the oblimin rotation, finding two solutions possibilities. one with two factors solution - the first one with 8 items (a = 0,82), called "negative view of self", explaining 32,4% of the variance and the second factor with 5 items (a = 0,77), called "physical function", explaining 8% of the variance - and other with one factor solution with 13 items, with really satisfactory reliability of 0,86, called "depression" and explaining 38% of the total variance.
Interaction between Shiga Toxin and Monoclonal Antibodies: Binding Characteristics and in Vitro Neutralizing Abilities
Letícia B. Rocha,Daniela E. Luz,Claudia T. P. Moraes,Andressa Caravelli,Irene Fernandes,Beatriz E. C. Guth,Denise S. P. Q. Horton,Roxane M. F. Piazza
Toxins , 2012, DOI: 10.3390/toxins4090729
Abstract: Monoclonal antibodies (MAbs) have been employed either for diagnosis or treatment of infections caused by different pathogens. Specifically for Shiga toxin-producing Escherichia coli (STEC), numerous immunoassays have been developed for STEC diagnosis, showing variability in sensitivity and specificity when evaluated by reference laboratories, and no therapy or vaccines are currently approved. Thus, the aim of this work was the characterization of the interaction between MAbs against Stx1 and Stx2 toxins and their neutralizing abilities to enable their use as tools for diagnosis and therapy. The selected clones designated 3E2 (anti-Stx1) and 2E11 (anti-Stx2) were classified as IgG1. 3E2 recognized the B subunit of Stx1 with an affinity constant of 2.5 × 10?10 M, detected as little as 6.2 ng of Stx1 and was stable up to 50 oC. In contrast, 2E11 recognized the A subunit of Stx2, was stable up to 70 oC, had a high dissociation constant of 6.1 × 10?10 M, and detected as little as 12.5 ng of Stx2. Neutralization tests showed that 160 ng of 3E2 MAb inhibited 80% of Stx1 activity and 500 μg 2E11 MAb were required for 60% inhibition of Stx2 activity. These MAb amounts reversed 25 to 80% of the cytotoxicity triggered by different STEC isolates. In conclusion, these MAbs show suitable characteristics for their use in STEC diagnosis and encourage future studies to investigate their protective efficacy.
Behcet?s disease and IgA nephropathy: report of this association in a patient from Brazil and literature review
Fernandes,Paula FCBC; Silva Júnior,Geraldo B; Barros,Fernando AS; Sousa,Daniela C; Franco,Luciano M; Patrocínio,Régia MSV;
Investigación Clínica , 2006,
Abstract: behcet?s disease (bd) is associated with renal involvement in about one-third of the cases and a variety of renal lesions have been reported. a 27-year-old man presented a history of recurrent oral and genital ulcers, associated with pseudofoliculitis and arthritis in his left knee. the first laboratory tests revealed: urea = 53mg/dl, creatinine = 1.8mg/dl. the urinalysis showed leukocyturia. initial treatment with ceftriaxone, thalidomide and prednisone was instituted. he became clinically stable, with normal renal function, but presenting hematuria and proteinuria. one year later the patient presented dark urine. the new laboratory tests showed urea = 58mg/dl, creatinine = 1.4mg/dl, and mild proteinuria (500-1000mg/24h). two years later the proteinuria was 2230mg/day. the renal biopsy showed one glomerulus with severe glomerular sclerosis, mild tubular atrophy, mild interstitial fibrosis and thickening of arterial walls. treatment with captopril was started to decrease proteinuria. two years later, the patient presented creatinine = 1.7mg/dl and proteinuria = 2509mg/day. a new renal biopsy evidenced proliferative crescentic glomerulonephritis, with diffuse granullary deposits of iga, igm and c3. it was instituted pulsotherapy with metilprednisolone, monthly endovenous cyclophosphamide and maintenance prednisone. the patient became clinically stable, with creatinine of 1.3mg/dl and proteinuria of 500mg/day. bd could be one of the various causes of secondary iga nephritis. it is important to periodically perform renal function evaluation in patients with bd, through urinalysis and measurement of serum creatinine and its clearance, in order to detect any abnormality and provide an early adequate treatment.
Transcranial sonography as a diagnostic tool for Parkinson's disease: a pilot study in the city of Rio de Janeiro, Brazil
Fernandes, Rita de Cássia Leite;Rosso, Ana Lucia Zuma de;Vincent, Maurice Borges;Silva, Kátia Silveira da;Bonan, Claudia;Araújo, Nordeval Cavalcante;Berg, Daniela;
Arquivos de Neuro-Psiquiatria , 2011, DOI: 10.1590/S0004-282X2011000700008
Abstract: in brazil there is no systematic study on transcranial sonography (tcs), a neuroimaging method that depicts echogenic deep brain structures using ultrasound. objective: to establish the percentage of subjects with permissive temporal windows and to address the ability of tcs of the substantia nigra (sn) to distinguish parkinsonian patients in a brazilian sample. method: we performed tcs using the acuson x300 (siemens, germany) in 37 individuals: 23 with parkinson's disease (pd) and 14 healthy controls. results: 10.8% of subjects had insufficient temporal acoustic bone windows. sn echogenic areas were larger in patients (mean±sd, 0.31±0.08cm2) compared to controls (mean±sd, 0.17±0.02cm2). tcs accurately identified 88.2% of pd patients. conclusion: a large proportion of brazilians seem to be eligible for tcs. an expressive number of pd patients could be diagnosed by tcs based on an expanded sn echogenic area. however, the current data is preliminary and must be corroborated by larger studies.
Percep??es e Sentimentos de Gestantes e Puérperas sobre a Pré-Eclampsia
Azevedo,Daniela Vasconcelos de; Araújo,Ana Cristina Pinheiro Fernandes de; Costa,íris do Céu Clara; Medeiros Júnior,Ant?nio;
Revista de Salud Pública , 2009, DOI: 10.1590/S0124-00642009000300004
Abstract: objective the present study was aimed at understanding how pregnant and postpartum women with preeclampsia perceived and experienced their condition. materials and methods interviews and observation were conducted with 20 women having preeclampsia between february and june 2007 in the outpatients department and hospitalisation ward of a public maternity hospital in north-eastern brazil. the analysis was based on gadamer's hermeneutics, with construction of thematic categories. results the women were aware of the gravity and some of the risks to which they were exposed; however, they had little knowledge about preeclampsia and its consequences and little information was given by the health professionals who were treating them. the most present feeling among these women was fear of death, fear of miscarriage and fear caused by lack of information about the disease. conclusions the perception of the gravity of the disease coupled to the little information given during treatment increased fear amongst these women. health professionals making high risk prenatal assistance more humanised (especially regarding preeclampsia) could facilitate an approach which would take the disease's emotional dimension into account during pregnant and postpartum women's clinical appointments.
Ansiedade e necessidades dos cuidadores de crian as com e sem deficiência La ansiedad y las necesidades de los cuidadores de ni os con y sin discapacidad Anxiety and needs of caregivers of disabled and non-disabled children
Cátia Priscila Lemos Fernandes,Daniela Elisabete Angélico Santos Cordeiro do Vale,Eduarda Beatriz dos Santos Nóbrega,Mirian Martins da Silva Dias
Revista de Enfermagem Referência , 2012,
Abstract: Objetivos: comparar os níveis de ansiedade dos cuidadores de crian as com deficiência com os dos cuidadores de crian as sem deficiência e conhecer o papel do enfermeiro no auxílio do cuidado das crian as, na opini o dos cuidadores. Enquadramento: os cuidadores das crian as com deficiência possuem responsabilidades na gest o da condi o crónica da crian a. A presta o desses cuidados pode ser prejudicial para a saúde física e bem-estar psicológico (King et al., 1999). Metodologia: estudo quantitativo, com amostra do tipo n o probabilística por conveniência, constituída por 56 indivíduos. Os dados foram recolhidos através de dois questionários constituídos por características sociodemográficas da amostra, grau de capacidade da crian a deficiente, escala de avalia o do apoio social à família, questionário relativo às dificuldades e necessidades das famílias e STAI. Resultados: os cuidadores de crian as com deficiência apresentam maiores níveis de ansiedade-estado e tra o relativamente aos outros cuidadores. A idade da crian a é preditiva de ansiedade. O enfermeiro pode ajudar os cuidadores de crian as com deficiência demonstrando mais carinho e paciência na sua interven o. Conclus o: o enfermeiro deve desenvolver iniciativas nos cuidados domiciliários, apoiando e informando os cuidadores para uma melhor presta o de cuidados, aliviando a sua sobrecarga. Assim, o desafio será diminuir a sobrecarga do cuidador. Objetivos: comparar los niveles de ansiedad de los cuidadores de ni os con discapacidad con aquellos de los cuidadores de ni os sin discapacidad y conocer el papel de la enfermera en el auxilio del cuidado de los ni os, según la opinión de los cuidadores. Introducción: los cuidadores de ni os con discapacidad tienen responsabilidades en la gestión de la condición crónica de la enfermedad del ni o. La prestación de dichos cuidado puede ser perjudicial a la salud física y el bienestar psicológico (King et al. 1999). Metodología: estudio cuantitativo, con una muestra de corte no probabilístico, constituida por 56 personas. Para la recolección de datos se utilizaron dos cuestionarios con las características sociodemográficas de la muestra, el grado de capacidad del ni o con discapacidad, la escala de valoración del apoyo social a la familia, un cuestionario sobre las dificultades y necesidades de las familias y el STAI. Resultados: los cuidadores de ni os con discapacidad presentan mayores niveles de ansiedad-estado y ansiedad-rasgo que los demás cuidadores. La edad del ni o es predictiva de ansiedad. La enfermera puede ayudar a los cuidadores de ni os c
Page 1 /234071
Display every page Item


Home
Copyright © 2008-2017 Open Access Library. All rights reserved.