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Search Results: 1 - 10 of 104635 matches for " Daniel Almeida da Costa "
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Photodynamic Therapy in the Healing of the Areolo-Papillary Complex after Mastectomy—Case Report  [PDF]
Maria da Glória Karan Marquetti Marquetti, Marcus Vinícius de Mello Pinto, Aline Ronis, Lamara Laguardia Valente Rocha, Julio Guilherme Silva, Anny Chi, Daniel Almeida Costa
Health (Health) , 2018, DOI: 10.4236/health.2018.103026
Abstract: Some breast reconstruction surgeries after mastectomy, or even reductive mammoplasty, may evolve unexpectedly when the areolopapillary complex heals and develop dehiscences, necrosis and delayed healing. The purpose of this case report was to verify the efficacy of photodynamic therapy in wound healing of the areolopapillary complex. This was a case report of a female patient with diabetes, fibromyalgia and diagnosed with breast cancer, with necrotic areolopapillary complex, after debridement, photodynamic therapy started with clobetasol propionate associated with methylene blue and low power laser application. At the beginning of the treatment with photodynamic therapy, the wound had 6 centimeters of diameter, and after 19 sessions, the wound was closed completely with normalization of the color of the nipple. The photodynamic therapy is advancing a lot in healing of infected wounds and complex wounds. It can be said that in this case report, photodynamic therapy was fundamental for the complete healing, being considered a promising treatment and another alternative for dermatofunctional physiotherapists.
Evaluation of the Therapeutic Response and Improvement in the Quality of Life of the Patient with Darier Disease to Acitretin through an Analogy between Close Relatives  [PDF]
Thiago Sande Miguel, Mateus de Oliveira Reis, Bruno Fonseca dos Santos, Aline da Silva Rocha, Nayrton Kalys Cruz dos Anjos, Lívia Cristina de Melo Pino, Daniel Almeida da Costa
Journal of Biosciences and Medicines (JBM) , 2017, DOI: 10.4236/jbm.2017.58004
Abstract: Darier disease (DD), also known as follicular keratosis, is a rare autosomal dominant hereditary acantholytic dermatosis caused by a mutation in the ATP2A2 gene. Skin lesions are characterized by persistent confluent papules, preferentially located on the seborrheic areas of the face, chest and back. The hands, feet and nails are also commonly affected. DD has a chronic course with frequent relapses. Their treatment is often difficult and unsatisfactory. We present the case of a 54-year-old male with a history of keratotic papules with a brownish-black color, with a foul-smelling, pruritic and ardent appearance on the back and trunk, since the age of 19, which worsen in the summer. His 27-year-old daughter has a similar picture with her skin lesions started at age of 17 in the region below the breast, back, trunk, feet and hands. After the skin biopsy, the diagnosis was confirmed and acitretin 30 mg/day was instituted. The importance of this case report is to alert health professionals that the diagnosis of DD should be considered in family members of patients, especially those in the first degree, and also in patients with follicular keratolytic dermatoses, being an important differential diagnosis of this group of patients diseases.
Ulcerated Lesion in Buccal Mucosa in a Patient with Paracoccidioidomycosis—Case Report  [PDF]
Giovanna Lima Vaz, Lívia Cristina de Melo Pino, Aline Gabriela Santos Costa, Ibrahim Yahia El Somailli, Jo?o Roberto Resende Fernandes, Elayne Christina Meireles Martins, Daniel Cohen Goldemberg, Aline Hellen da Silva Camacho, Rhanna Neves Cirqueira, Daniel Almeida da Costa
Journal of Biosciences and Medicines (JBM) , 2017, DOI: 10.4236/jbm.2017.510005
Abstract: Paracoccidioidomycosis is the most prevalent systemic mycosis in Latin America. It is a fungal infection caused by the dimorphic fungus Paracoccidioides brasiliensis. This microorganism can penetrate the human body through direct contact and can cause intense lymphadenopathy, ulcerated lesions in the oral cavity and in the skin among other alterations. In this study, we report a case of paracoccidioidomycosis with unusual clinical presentation, as it manifested in the female sex and although it did not present any relevant complaints of respiratory focus, it presented a single ulcerated lesion in the buccal mucosa. A biopsy of the lesion and a mycological examination revealed Paracoccidioidesbrasiliensis infection.
Profile of Patients with Stroke and Disorders of the Vocal Tract  [PDF]
Lina Claudia Pereira Lopes, Daniel Almeida da Costa, Marcus Vinicius de Mello Pinto, Aline Ronis Sampaio, Lamara Laguardia Valente Rocha, Isabela Nardoni Bernardes, Rafael Batista Ferreira, Elias Sobreira Sathler, R. R. B. T. Vieira
World Journal of Neuroscience (WJNS) , 2017, DOI: 10.4236/wjns.2017.71008
Abstract: Background: The present work aims to characterize the profile of patients with stroke treat at a hospital located in the Region of the Mata of Minas Gerais, Brazil, considering the findings of the clinical vocal tract, kind of stroke, age and gender of such patients. Methodology: To obtain data, the clinical profile of 133 patients with a clinical or tomography diagnosis of stroke was analyzed, and the results were presented in percentage. For quantitative data average and analysis the tests were done with associations that held χ2 test, and for significance it was considered p < 0.05. Results: From the total of patients, 63 were women, accounting for 47.4% and the other 52.6% were males. Clinically, they were characterized with the highest percentage for ischemic stroke (89.4%) compared to the hemorrhagic type (10.6%). Most of them were referred for computed tomography (86.5%) and remained hospitalized for an average of 6.496 ± 7.372 days. Similar percentages were obtained in the analysis of the population in question, when considering if they had (54.1%) or not (49.6%) any damage in their speech, language skills or swallowing. There were different types of disabilities in patients with stroke. Men with an average age of 69.8 ± 13.9 presents mostly ischemic stroke, and the majority of patients with stroke had hemiplegia and abnormalities of the vocal tract, dysphasia, and aphasia. While older patients had an ischemic stroke and were presented with left hemiplegia, the younger ones suffered from hemorrhagic strokes that caused a disability characterized as right hemiplegic. Conclusion: Our results show important conclusions regarding the clinical evolution of the vocal tract of patients who suffered strokes during the period of the analysis, being useful for better comprehension of how the vocal tract from these patients evolved according to the kind of stroke, sex and age also allowing a contraposition with other future statistics periods available in literature. It can also be pointed out the difficulties in diagnosing the stroke and the concern with the immediate care, but not with its continuance or with its multidisciplinary approach, giving an evident life risk through dysphasia and the increase of permanent damage when there isn’t an appropriate work done with the patients.
Effects of Gaseous Drinks in Wistar Rats Esophagus  [PDF]
Thiago Dornelas de Oliveira, Marcelli Eliotério Gaspar, Larissa Menezes Viana Braga, Joice Meire Rodrigues, Rebeca Nogueira Falc?o Santos, Suelen Gaudino Moura, Nayara Barbosa Bicalho, Lamara Laguardia Valente Rocha, Daniel Almeida da Costa, Marcus Vinicius de Mello Pinto
Journal of Biosciences and Medicines (JBM) , 2017, DOI: 10.4236/jbm.2017.55004
Abstract: The consumption of beverages and processed foods, mainly soft drinks, has been incorporated into the usual diet of children, adolescents and adults frequently in recent years. The present study aimed to study the effects of carbonated drinks on Wistar rats, based on the macroscopic and histological morphology of the esophagus. Fifteen Wistar rats were divided into three groups: control group; group fed with ration and cola-type refrigerant ad libitum and group fed with ration and gas industrialized water ad libitum, for a trial period of 90 days. For histopathology and morphology, the esophagus was removed, prepared in slides and stained with hematoxylineosin. Images of the sections were captured for analysis and classification of the inflammatory infiltrate. For morphometry, ten grid fields of 100 points were evaluated in the 40x eyepiece, totaling 3000 points per animal. The results demonstrate that the refrigerant treatment induced the following structural changes in the rats: significant reduction of weight in relation to the control group; inflammatory infiltrate predominantly diffuse mild to moderate and tissue edema. The rats treated with carbonated water had similar results to the control, besides signs of healing and tissue repair.
Evaluation of Cytotoxicity of Gossypium barbadense L. Extract in Bone Cord Cells through the Micronucleus Test  [PDF]
Thiago Dornelas de Oliveira, Joice Meire Rodrigues, Thiago Sande Miguel, Nayrton Kalys Cruz dos Anjos, Juscélio Clemente de Abreu, Lamara Laguardia Valente Rocha, Raquel Xavier Ligeiro Dias, Daniel Almeida da Costa
Journal of Biosciences and Medicines (JBM) , 2017, DOI: 10.4236/jbm.2017.57008
Abstract: The cotton plant is a plant belonging to the family Malvaceae and its leaves are often used in folk medicine. The present study aimed to evaluate the mutagenic or antimutagenic activity of the ethanolic extract of Gossypium barbadense L. (EEG) and to analyze its capacity to prevent or repair mutagenic lesions caused by cyclophosphamide (CP). For the Micronucleus test, Swiss mice were divided into 5 groups: negative control; Positive control: treated with 50 mg/kg cyclophosphamide (CP), group receiving EEG 500 mg/kg for 7 days; Group receiving EEG 500 mg/kg for 7 days associated with CP24h before euthanasia; Group who received CP and EEG 500 mg/kg for 7 days. After the treatment period, the animals were euthanized, the bone marrow removed and the blood smear prepared. From this analysis, it was observed that the EEG caused a significant increase in the number of micronucleated erythrocytes, indicating mutagenic activity of the extract. In addition, it was verified that the extract did not present the capacity to prevent, but it presented the capacity of repair of the chromosomal damages caused by CP.
Subacute Cutaneous Lupus Erythematosus in Older Man: Case Report  [PDF]
Debora Trindade Martins, Thiago Sande Miguel, Nayrton Kalys Cruz dos Anjos, Sebasti?o Celio Horta Coelho Filho, Vinicius Moreira Paladino, Bruna Sande Miguel, Vinicius Sande Miguel, Daniel Almeida da Costa, Livia Cristina de Melo Pino
Journal of Biosciences and Medicines (JBM) , 2017, DOI: 10.4236/jbm.2017.510003
Abstract: Systemic lupus erythematosus (SLE) is an autoimmune disease that affects mainly women, presents several clinical manifestations and has no known exact cause. The skin is one of the organs that can be affected, with subacute cutaneous lupus erythematosus (SCLE) being one of the classifications according to cutaneous lupus erythematosus lesions. SCLE is commonly found in young to middle age women and carries characteristics related to sun exposure. In this report, there is a rare case of a male and elderly patient that presents SCLE subgroup initially asymptomatic, with subsequent appearance of macular skin lesions and vitiligo appearance. This is an important case to alert health professionals that the disease can manifest itself and open its clinical profile even in patients of sex and unusual ages.
Main Microbial Genres and Its Profile of Resistance and Sensitivity to Antimicrobials Used in the Treatment of Oncological Patients with Febril Neutropenia  [PDF]
Hélvecio Cardoso Póvoa, Richard Raphael Borges Tavares Vieira, Elias Sobreira Sathler, Isabela Nardoni Bernardes, Rafael Batista Ferreira, Mário Henrique Couto Lima, Thiago Sande Miguel, Nayrton Kalys Cruz dos Anjos, Lamara Laguardia Valente Rocha, Daniel Almeida da Costa
Journal of Biosciences and Medicines (JBM) , 2018, DOI: 10.4236/jbm.2018.61005
Abstract: Objective: To determine the main microbial genotypes and their antimicrobial resistance and susceptibility profile commonly used in the treatment of oncologic patients with febrile neutropenia, carried out through the review of the clinical histories of the patients’ medical records at the Hospital do Cancer de Muriaé-Fundacao Cristiano Varella. Methods: Quantitative research, determined the susceptibility profile of microorganisms in patients with febrile neutropenia from April 2007 to April 2008 by reviewing clinical histories of patients’ medical records at the referred hospital. Results: Of the total of 8 patients evaluated with Gram-negative microorganisms, 50% of the patients were female and 50% were male. Of the 18 patients evaluated with Gram-positive microorganisms 66% were female and 34% male. Gram-positive bacteria are prevalent and cause around 60% of documented bacteremias, although Gram-negative bacteria are more common in febrile neutropenic patientes. Conclusion: Exaggerated use of antimicrobials in hospitalized patients leads to the suppression of drug-sensitive microorganisms from the intestinal flora and promotes the persistence and growth of resistant bacteria. The antibiotic should be used in a curative manner with other therapeutic measures with the determined bacterial infection.
Importance of Primary Health Care in Medicine: Simultaneous Analysis of Two Colleges, under the Vision of Teachers and Students  [PDF]
Sebasti?o Célio Horta Coelho Filho, Thiago Sande Miguel, Nayrton Kalys Cruz dos Anjos, Mateus de Oliveira Reis, Bruna Sande Miguel, Vinicius Sande Miguel, Aline Gabriela Santos Costa, Lilian Costa Brito, Bruno Fonseca dos Santos, Ver?nica Clemente Villar Martini, Daniel Almeida da Costa
Journal of Biosciences and Medicines (JBM) , 2017, DOI: 10.4236/jbm.2017.511002
Abstract: Introduction: The involvement of undergraduate student at the beginning of their training in activities based on Primary Health Care (PHC), provides preventive and health promoting actions, and ensures the evaluation of the vulnerability of communities and people. Objectives: To analyze the opinion of students and teachers of two medicine higher education institutions on the relevance of Primary Health Care in this course. METHODS: Students and teachers should be effectively enrolled in order for the study to be conducted, being chosen in a random manner and without interferences on the part of the researchers so that the work was as reliable as possible. A cross-sectional study was conducted with interviews structured in questionnaires about what they thought about PHC. To some students and teachers of the medical course of Valen?a and Grande Rio University (UNIGRANRIO). Before receiving the questionnaire, all interviewed signed a Free and Informed Consent Term, which included the objectives and methodology of the work. Results: 310 students and 51 teachers participated in the study, where 91.43% of the students and 100% of the teachers affirmed that primary care plays a fundamental role in medical education. 94.86% of students and 97.91% of teachers, claimed that the discipline allows a greater contact between undergraduates and community. When questioned about the encouragement that teachers give to students to pursue a career in PHC, 57.87% of the students and 70.83% of the professors said they lacked in such a stimulus. Conclusion: PHC is still very neglected by governmental policies, educational institutions and by the own teachers, that often, turn they attention only to tertiary medicine and, as a consequence, a discouragement of this area occur. Therefore, a higher PHC value is necessary, allowing a more humane look at the patient, valuing their feelings, anguishes and their pathological framework.
Nodular Amyloidosis Overlapping and Polymyositis in a Patient with Skin Manifestations Lupus Fax: Case Report  [PDF]
Enéas Van Der Maas do Bem Filho, Laíza Maria dos Santos Couto, Ant?nio Luiz da Costa Soares Jr., Pedro Paulo Andrade, Thiago Sande Miguel, Sebasti?o Célio Horta Coelho Filho, Daniel Almeida da Costa, Lívia Cristina de Melo Pino, Thayro Van Der Maas do Bem
Journal of Biosciences and Medicines (JBM) , 2017, DOI: 10.4236/jbm.2017.511005
Abstract: Amyloidosis is the result of fibrous and insoluble amyloid protein deposition in extracellular spaces of tissues and organs, including the skin. Through the analysis of medical records, clinical condition and laboratory tests, this article proposes a rare case report of an adult patient with symptoms and diagnosis of polymyositis, histopathology of nodular amyloidosis with skin lesions suggestive of lupus. The patient is still being followed at the dermatology clinic of Valença Medical School, in order to improve the prognosis and prevent the progression of existing symptoms.
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