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Search Results: 1 - 10 of 474673 matches for " Dalton A.;Lima "
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Utiliza??o de saponina em citometria de fluxo: uma alternativa factível para permeabiliza??o celular
Pereira, Juliana;Brocardo-Lima, Graciela A.;Beitler, Beatriz;Chamone, Dalton A. F.;
Revista Brasileira de Hematologia e Hemoterapia , 2007, DOI: 10.1590/S1516-84842007000200006
Abstract: intracellular antigen investigations by means of flow cytometry are essential for immune phenotypical studies of oncohematological diseases. the use of saponin for cellular permeabilization has proved to be cost-effective. due to its detergent properties, saponin permeabilizes the cytoplasmatic membrane without harming it or altering membrane antigen expressions, thus allowing simultaneous detection of intracellular and surface antigens. the objective was to analyze the efficiency of the cell permeabilization technique using saponin as a permeabilizing agent. thirty-six samples of peripheral blood and bone marrow underwent an immune phenotypical study at the immune pathology laboratory of the hospital das clínicas of the university of s?o paulo. direct immunofluorescence was accomplished using the cellquest program (becton dickinson, san jose, ca) of the facscalibur flow cytometer (becton dickinson, san jose, ca) to acquire and analyze the data. excessive cell loss was observed when using rinsing buffers stored for more than seven days at temperatures ranging from 2oc to 8oc. minimal cell loss was found when rinsing buffers were used immediately after preparation or frozen at the time of preparation and thawed just before use. in order to eliminate excessive cell loss, a systematic analysis of the technique stages was carried out, allowing us to restructure the technique to our purposes and its use in our laboratory. in a country with scarce resources, a viable, faster, more cost-effective technique (35% reduction in cost) aimed at investigating intracellular antigens by flow cytometry has been standardized.
MI-SBTVD: a proposal for the Brazilian digital television system SBTVD
Mendes, Luciano L.;Brito, José Marcos C.;Cardoso, Fabbryccio A.;Guimar?es, Dayan A.;Lima, Gustavo C.;Gomes, Geraldo G. R.;Arantes, Dalton S.;Souza, Richard D.;
Journal of the Brazilian Computer Society , 2007, DOI: 10.1590/S0104-65002007000100007
Abstract: the objective of this paper is to present a general overview of the innovative modulation system project -mi-sbtvd - developed for the brazilian digital tv system. the mi-sbtvd project includes an ldpc high performance error correcting code, an advanced transmit spatial diversity and an efficient multi-carrier modulation scheme. the building blocks of the system, its characteristics and most relevant innovations are presented. the performance of the whole system under different channels is compared with the performance of the present-day digital television standards. the complete system was implemented in fpga using vhdl language and rapid prototyping tools for dsp algorithms.
Fraturas diafisárias de fêmur em crian?as e adolescentes
Cunha, Fernando Milton da;Figueiredo, Leandro Azevedo de;Coelho, Luís Felipe Albeny;Malheiros, Dorotéa Starling;Terra, Dalton Lopes;Lima, César Luís Ferreira Andrade;
Acta Ortopédica Brasileira , 2007, DOI: 10.1590/S1413-78522007000200004
Abstract: seventy one patients below the age of 16, with 72 shaft femur fractures occurred between january 1995 and december 1998, were evaluated. the purpose of the study was to understand the descriptive aspects of the fractures and appraise the employed treatment. age was the key criterion for treatment choice, with those under 3 years old (group i) being treated with immediate spica cast; those between 3 and 10 years (group ii) were treated with traction followed by spica cast, and those over 11 years old (group iii) with conservative or surgical therapy. mean age was 6.3±3.8 years with a prevalence of males and closed fractures. traffic accident was the most common injury cause. the fracture was in the middle third in 60.6% of the cases, in the proximal third in 23.9%, and in the distal third in 15.5%. ninety three percent were simple trace fractures, 4.2% comminutive and 2.8% segmental. associated injuries were identified in 35.2% of the patients. all fractures in groups i, ii and 60.0% of those in group iii were treated conservatively. complications seen until bone union were: discrepancy, infection at the wire path, vicious union and limited knee motion. the average time for union was 8.6±3.4 weeks, varying with age. we conclude that the studied fractures' characteristics were similar to those described by current literature and that the employed treatment showed good outcomes.
Localiza o Varejista: Um Estudo sobre a Utiliza o do Modelo de Huff para a Tomada de Decis es sobre Localiza o
Andre Giffoni Pellizzaro Lima,Dalton Jorge Teixeira
Revista Gest?o & Tecnologia , 2008,
Abstract: O objetivo desta pesquisa foi desenvolver um estudo sobre estratégia de localiza o de lojas. Utilizou-se o modelo desenvolvido por Huff, que permite escolher, entre as prováveis localiza es de um ponto comercial, a melhor op o para a abertura de uma loja. Foi realizada uma pesquisa descritiva, e a coleta de dados foi feita por meio da aplica o de questionário estruturado. A regi o escolhida para a pesquisa concentra número relevante de drogarias. A pesquisa de campo foi realizada com aplica o do questionário a indivíduos residentes no bairro. O modelo permitiu identificar a área de influência da loja estudada. Este estudo revelou-se um trabalho original ao focar a localiza o de drogarias por meio da utiliza o do Modelo de Huff, permitindo, assim, contribuir para a realiza o de novas pesquisas acadêmicas e dar suporte aos varejistas nas quest es relativas à localiza o.
Localiza o Varejista: Um Estudo sobre a Utiliza o do Modelo de Huff para a Tomada de Decis es sobre Localiza o
Andre Giffoni Pellizzaro Lima,Dalton Jorge Teixeira
Revista Gest?o & Tecnologia , 2010,
Abstract: O objetivo desta pesquisa foi desenvolver um estudo sobre estratégia de localiza o de lojas. Utilizou-se o modelo desenvolvido por Huff, que permite escolher, entre as prováveis localiza es de um ponto comercial, a melhor op o para a abertura de uma loja. Foi realizada uma pesquisa descritiva, e a coleta de dados foi feita por meio da aplica o de questionário estruturado. A regi o escolhida para a pesquisa concentra número relevante de drogarias. A pesquisa de campo foi realizada com aplica o do questionário a indivíduos residentes no bairro. O modelo permitiu identificar a área de influência da loja estudada. Este estudo revelou-se um trabalho original ao focar a localiza o de drogarias por meio da utiliza o do Modelo de Huff, permitindo, assim, contribuir para a realiza o de novas pesquisas acadêmicas e dar suporte aos varejistas nas quest es relativas à localiza o.
Functional electrical stimulation improves brain perfusion in cranial trauma patients
Amorim, Bárbara Juarez;Santos, Allan de Oliveira;Oberg, Telma Dagmar;Romanato, Juliana;Anjos, Dalton A.;Lima, Mariana da Cunha Lopes de;Ramos, Celso Darío;Honorato, Donizete Cesar;Camargo, Edwaldo Eduardo;Etchebehere, Elba Cristina de Sá Camargo;
Arquivos de Neuro-Psiquiatria , 2011, DOI: 10.1590/S0004-282X2011000500020
Abstract: objective: demonstrate brain perfusion changes due to neuronal activation after functional electrical stimulation (fes). method: it was studied 14 patients with hemiplegia who were submitted to a program with fes during fourteen weeks. brain perfusion spect was performed before and after fes therapy. these patients were further separated into 2 groups according to the hemiplegia cause: cranial trauma and major vascular insults. all spect images were analyzed using spm. results: there was a significant statistical difference between the two groups related to patient's ages and extent of hypoperfusion in the spect. patients with cranial trauma had a reduction in the hypoperfused area and patients with major vascular insult had an increase in the hypoperfused area after fes therapy. conclusion: fes therapy can result in brain perfusion improvement in patients with brain lesions due to cranial trauma but probably not in patients with major vascular insults with large infarct area.
The Stellar Black Hole  [PDF]
Kenneth Dalton
Journal of High Energy Physics, Gravitation and Cosmology (JHEPGC) , 2018, DOI: 10.4236/jhepgc.2018.44037
Abstract: A black hole model is proposed in which a neutron star is surrounded by a neutral gas of electrons and positrons. The gas is in a completely degenerate quantum state and does not radiate. The pressure and density in the gas are found to be much less than those in the neutron star. The radius of the black hole is far greater than the Schwarzschild radius.
What can we learn from study of Alzheimer's disease in patients with Down syndrome for early-onset Alzheimer's disease in the general population?
Robyn A Wallace, Arthur J Dalton
Alzheimer's Research & Therapy , 2011, DOI: 10.1186/alzrt72
Abstract: Human thinking depends, ultimately, on the integrity of brain cell to brain cell communication. Any process that impairs this communication - whether it is congenital or acquired, static or degenerative, anatomic or metabolic - has devastating consequences for the health and well-being of that person. People with intellectual disabilities endure socioeconomic and health disparities as a consequence of their cognitive impairment [1]. Similarly, people with acquired cognitive impairments suffer losses in work and social status with economic and familial hardships. While the biopsychosocial barriers facing people with acquired and congenital cognitive impairments must be addressed by society, knowledge of how to prevent or cure cognitive impairment also plays a role in society's responsibility for their care.Alzheimer's dementia is a neurodegenerative disease of the brain causing progressive cognitive impairment affecting three distinct population groups: most adults with Down syndrome aged >50 years; an early-onset group comprising people aged <60 years with specific genetic predispositions; and the largest, so-called late-onset group, a majority of the very older people. The onset of Alzheimer's dementia has profound implications for health, social and economic well-being of all the people in whom this disease develops. This applies equally for people with pre-existing intellectual disability as well as those starting with normal cognition [2,3]. Knowledge of the cause or causes of Alzheimer's disease contributes to understanding the processes of usual cognition and the cognitive changes, and potentially points research in the direction of disease prevention or cure.In fundamental but as yet incomplete ways, studies of the cognitive skills, brains and genetics of people with Down syndrome have contributed to understanding processes not only of both normal and abnormal thinking, but also of cognitive changes and neuropathology in Alzheimer's disease development in the
THE EFFECT OF TELE-MONITORING ON EXERCISE TRAINING ADHERENCE, FUNCTIONAL CAPACITY, QUALITY OF LIFE AND GLYCEMIC CONTROL IN PATIENTS WITH TYPE II DIABETES
Tracy Marios,Sara Dalton,Neil A. Smart
Journal of Sports Science and Medicine , 2012,
Abstract: We used tele-monitoring to attempt to improve exercise adherence (number of hours of exercise completed), peak VO2, HbA1c% and quality of life in an unsupervised, home based exercise program in people with type II diabetes, a cost analysis was also conducted. Thirty-nine patients with type II diabetes were randomized to tele-monitoring (TELE) or control (CON) groups. All patients were asked to complete 6 months exercise training and complete an exercise activity diary. The TELE group was instructed to record their exercise heart rates using a monitor and received weekly telephone calls from an exercise physiologist. Six TELE patients and seven CON patients did not complete the 6 month testing. TELE patients completed a mean weekly volume of 138 minutes, moderate intensity exercise, while CON patients completed 58 minutes weekly (p < 0.02). Neither group achieved the American Heart Association statement guideline for weekly exercise volume of 150 minutes. TELE patients improved peak VO2 (5.5 %), but neither group improved HbA1c% or quality of life. The CON group showed a 4.9% reduction in peak VO2. While tele-monitored patients completed more hours of exercise and demonstrated improved peak VO2 compared to controls, the exercise volume completed was insufficient to improve glycemic control. There is the potential via tele-monitoring to enable people with diabetes to meet exercise training guidelines.
Field Quantization, Photons and Non-Hermitean Modes
S. A. Brown,B. J. Dalton
Physics , 2001, DOI: 10.1080/09500340110095625
Abstract: Field quantization in three dimensional unstable optical systems is treated by expanding the vector potential in terms of non-Hermitean (Fox-Li) modes in both the cavity and external regions. The cavity non-Hermitean modes (NHM) are treated using the paraxial and monochromaticity approximations. The NHM bi-orthogonality relationships are used in a standard canonical quantization procedure based on introducing generalised coordinates and momenta for the electromagnetic (EM) field. The quantum EM field is equivalent to a set of quantum harmonic oscillators (QHO), associated with either the cavity or the external region NHM. This confirms the validity of the photon model in unstable optical systems, though the annihilation and creation operators for each QHO are not Hermitean adjoints. The quantum Hamiltonian for the EM field is the sum of non-commuting cavity and external region contributions, each of which is sum of independent QHO Hamiltonians for each NHM, but the external field Hamiltonian also includes a coupling term responsible for external NHM photon exchange processes. Cavity energy gain and loss processes is associated with the non-commutativity of cavity and external region operators, given in terms of surface integrals involving cavity and external region NHM functions on the cavity-external region boundary. The spontaneous decay of a two-level atom inside an unstable cavity is treated using the essential states approach and the rotating wave approximation. Atomic transitions leading to cavity NHM photon absorption have a different coupling constant to those leading to photon emission, a feature resulting from the use of NHM functions. Under certain conditions the decay rate is enhanced by the Petermann factor.
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