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Search Results: 1 - 10 of 26735 matches for " DX Jin "
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Reverse LISS plating for intertrochanteric Hip Fractures in elderly patients
CQ Zhang, Y Sun, DX Jin, C Yao, SB Chen, BF Zeng
BMC Musculoskeletal Disorders , 2010, DOI: 10.1186/1471-2474-11-166
Abstract: We treated 28 elderly patients with a mean age of 82.3 years. According to the Evens classification, there were 2 Type I fractures, 2 Type II fractures, 3 Type III fractures, 13 Type IV fractures, 6 Type V fractures and 2 Type R fractures. All fractures were treated using the reverse LISS. Radiographic and clinical evidence of functional outcome and complications were evaluated.Mean perioperative blood loss was 92.4 milliliters (range 35 to 245 milliliters), and the mean postoperative hospital stay was 8.7 days (range 3 to 14 days).Complications included one minor wound hematoma. Radiographically, no collapses, screw cutouts, or head penetrations were seen. All surviving patients (28 of 28; 100 percent) had uneventful fracture healing with union achieved by six months in all patients.Use of the Reverse LISS plating for intertrochanteric hip fractures resulted in event-free fracture healing.Hip fractures are a leading cause of death and disability among the elderly. Approximately 50% of hip fractures are intertrochanteric fractures, a large percentage of which are unstable [1,2]. Treatment goals for this patient population include early rehabilitation, restoration of the anatomic alignment of the proximal part of the femur, and maintenance of the fracture reduction [3]. Different approaches have been used to solve this problem, including trochanteric osteotomy techniques, cementing, and different types of fixation devices. Despite improved techniques and devices, failure of fixation is still a problem in unstable intertrochanteric fractures[4].In recent years, the minimally invasive surgical techniques have led to a widespread use of many new implants [5,6]it has been shown that they can reduce operative complications and postoperative morbidity. As such, the present study evaluates the treatment of intertrochanteric hip fractures with the reverse LISS plating system.The present study was reviewed and approved by our institutional review board, and informed consent w
Polymorphism of the VEGF gene and its association with growth traits in four goat breeds
QJ Jin, XT Fang, CL Zhang, L Yang, JJ Sun, DX Chen, XY Shi, Y Du, XY Lan, H Chen
South African Journal of Animal Science , 2010,
Abstract: The vascular endothelial growth factor (VEGF) is a regulator of angiogenesis which is an important physiological adaptation to increased metabolic demand. Thus, mutations of this gene may exert a significant influence on animal growth. We screened the exons of the caprine VEGF gene using PCR-SSCP and DNA sequencing methods in 459 individuals from four goat breeds to identify sequence variations that may have an effect on protein structure and function, and might be related to different phenotypes of growth traits. Two single nucleotide polymorphisms (SNPs) (GU014696:g.49 G>C and GU014696:g.270G>A) were identified in the P3 locus of the caprine VEGF gene. Significant associations were observed between the genotypes of the P3 locus and body length, body height and chest circumference. Individuals with genotype P3-B had a significantly longer body length and higher body height than individuals containing genotype P3-AB. Thus, animals of genotype P3-AB should be culled in a selection programme for fast growth. It is suggested that P3-B could be used as a molecular marker in marker-assisted selection (MAS).
Spatial-temporal dynamic change of land resource degradation in China

Zhang Ke-feng,Li Xian-wen,Zhang Ding-xiang,Peng Jin-fu,Chen Jian,Yu Zhen-rong,
Zhang KF
,Li XW,Zhang DX,Peng JF,Chen J,Yu ZR

环境科学 , 2006,
Abstract: Large scale spatial and temporal land use survey data were used to study the dynamics of land use change in China recently. With the aid of GIS, the spatial-temporal dynamic change of land resource degradation at the national level was investigated using authoritative datasets from detailed land use surveys (early 1990s approximately 2003). As a result, seven major types of land degradation processes were identified, including sandy desertification, rocky desertification, secondary salinification, non-agricultural land occupation, deforestation, natural grassland degradation and wetlands shrinking. This paper comprehensively explored the characteristics of these land degradation processes and revealed the status and trend of the holistic land resource degradation in China. Results shows that: (1) Although land degradation has been controlled in local area, but it is still continuing to spread in the whole country. The total degradation index of the holistic land resource presented fluctuating trend. Indexes of non-agricultural construction occupation and wetland shrinking process are far more than that of other process, which are two primary causes contribution to heading straight towards full-scale land resource deterioration in China. (2) Land resource degradation process of China focused on natural grass land, and non-agricultural construction land, which attained 66.27%; Land resource degradation rehabilitation mainly focused on desertification and forest restoration, which accounts for 57.5%. (3) Sandy desertification and rocky desertification process have been reversing greatly. The total net change of their quantities was decreased by 15,578km2. But most of the rehabilitation of land desertification was concentrated on the originally ecological vulnerable northwestern zone, whereas newly added desertified land has been expanding and aggravating in eastern zone, especially around river watersheds. (4) Over two-thirds of non-agriculture land expansion came from cultivated land. In addition, almost 60 percent of the loss cultivated land occupied by non-agricultural land was appeared in the Northeast, the Eastern coast and Central China where have many high productive agricultural lands of China. This kind of land degradation has threatened food security of China seriously. (5) However, large scale reclamation of ecological land transferred into cultivated land was the most dominant factor of degradation. For example, the conversion of wetland resource to croplands by reclamation accounts for over 50 percent of wetland shrinking.
Isolation of dimorphic chloroplasts from the single-cell C4 species Bienertia sinuspersici
Shiu-Cheung Lung, Makoto Yanagisawa, Simon DX Chuong
Plant Methods , 2012, DOI: 10.1186/1746-4811-8-8
Abstract: The majority of terrestrial plants house chloroplasts primarily in one major cell type of leaves (i.e. mesophyll cells), and perform C3 photosynthesis to assimilate atmospheric CO2 into a 3-carbon product, 3-phosphoglyceric acid. In C4 species, on the other hand, a Kranz-type leaf anatomy featuring the second type of chlorenchyma cells surrounding the vascular bundles (i.e. bundle sheath cells) was reported as early as in the late 1800's [1]. In these species, the initial carbon fixation into 4-carbon acids was first documented in the 1960's [2,3]. The physiological relevance of the Kranz anatomy in relation to the C4 photosynthetic pathways, however, had not been elucidated until the successful separation of the two types of chlorenchyma cells and their respective dimorphic chloroplasts. With the development of various mechanical and enzymatic methods for separating the mesophyll and bundle sheath cells, the biochemistry of C4 cycles has been intensively studied over the past few decades focusing explicitly on characterizing the enzymatic properties and determining their precise subcellular locations in these cell types (for review, see [4]), leading to the current C4 models. In the C4 model, atmospheric CO2 is initially converted into C4 acids by phosphoenolpyruvate carboxylase (PEPC) in mesophyll cells. The C4 acids are broken down by a C4 subtype-specific decarboxylation enzyme in bundle sheath cells, and the liberated CO2 is subsequently re-fixed by ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco). The C4 pathway concentrates CO2 at the site of Rubisco and minimizes the photorespiration process, an unfavorable oxygenase activity of Rubisco with O2.The indispensable relationship between the Kranz anatomy and C4 photosynthesis has been an accepted feature until the discovery of three terrestrial single-cell C4 species, Suaeda aralocaspica (formerly called Borszczowia aralocaspica) [5], Bienertia cycloptera [6,7], and B. sinuspersici [8] in the Chenopodia
Egg white-mediated green synthesis of silver nanoparticles with excellent biocompatibility and enhanced radiation effects on cancer cells
Lu RQ, Yang DP, Cui DX, Wang ZY, Guo L
International Journal of Nanomedicine , 2012, DOI: http://dx.doi.org/10.2147/IJN.S29762
Abstract: g white-mediated green synthesis of silver nanoparticles with excellent biocompatibility and enhanced radiation effects on cancer cells Original Research (4604) Total Article Views Authors: Lu RQ, Yang DP, Cui DX, Wang ZY, Guo L Published Date April 2012 Volume 2012:7 Pages 2101 - 2107 DOI: http://dx.doi.org/10.2147/IJN.S29762 Received: 08 January 2012 Accepted: 21 February 2012 Published: 24 April 2012 Renquan Lu1, Dapeng Yang2, Daxiang Cui2, Zhongyang Wang3, Lin Guo1 1Department of Clinical Laboratory, Fudan University Shanghai Cancer Center, Shanghai, 2Department of Bio-Nano-Science and Engineering, National Key Laboratory of Nano/Micro Fabrication Technology, Key Laboratory for Thin Film and Microfabrication of Ministry of Education, Institute of Micro-Nano Science and Technology, Shanghai Jiao Tong University, Shanghai, 3College of Chemistry and Chemical Engineering, Yantai University, Shan Dong Province, People's Republic of China Abstract: A simple, cost-effective, and environmentally friendly approach to the aqueous-phase synthesis of silver (Ag) nanoparticles was demonstrated using silver nitrate (AgNO3) and freshly extracted egg white. The bio-conjugates were characterized by UV-visible spectroscopy, transmission electron microscopy, Fourier transform infrared spectrometry, and dynamic light scattering. These results indicated that biomolecule-coated Ag nanoparticles are predominantly spherical in shape with an average size of 20 nm. The proteins of egg white, which have different functional groups, played important roles in reducing Ag+ and maintaining product attributes such as stability and dispersity. In vitro cytotoxicity assays showed that these Ag-protein bio-conjugates showed good biocompatibility with mouse fibroblast cell lines 3T3. Furthermore, X-ray irradiation tests on 231 tumor cells suggested that the biocompatible Ag-protein bio-conjugates enhanced the efficacy of irradiation, and thus may be promising candidates for use during cancer radiation therapy.
JZhang,DX Zou,ZZ Zhang,Z Y Zhong,

金属学报(英文版) , 1996,
Abstract: ACOMPONENT-SPECIFICALLOYDESIGNOFTiAlINTERMETALLICSJ.Zhang;D.X.Zou;Z.Z.ZhangandZ.YZhong(CentralIron&SteelResearchInstitute,Bei...
Improvement of Mechanical Properties of Martensitic Stainless Steel by Plasma Nitriding at Low Temperature

YT Xi,DX Liu,D Han,ZF Han,

金属学报(英文版) , 2008,
Abstract: A series of experiments were carried out to study the influence of low temperature plasma nitriding on the mechanical properties of AISI 420 martensitic stainless steel. Plasma nitriding ezperiments were carried out for 15 h at 350℃ by means of DC-pulsed plasma in 25%N2 75%H2 atmosphere. The microstructure, phase composition, and residual stresses profiles of the nitrided layers were determined by optical microscopy and X-ray diffraction. The microhardness profiles of the nitridied surfaces were also studied. The fatigue life, sliding wear, and erosion wear loss of the untreated specimens and plasma nitriding specimens were determined on the basks of a rotating bending fatigue tester, a ball-on-disc wear tester, and a solid particle erosion tester. The results show that the 350℃ nitrided surface is dominated by ε-Fe3N and αN, which is supersaturated nitrogen solid solution. They have high hardness and chemical stabilities. So the low temperature plasma nitriding not only increases the surface hardness values but also improves the wear and erosion resistance. In addition, the fatigue limit of AISI 420 steel can also be improved by plasma nitriding at 350℃ because plasma nitriding produces residual compressive stress inside the modified layer.
The peroxisomal multifunctional protein interacts with cortical microtubules in plant cells
Simon DX Chuong, Nam-Il Park, Michelle C Freeman, Robert T Mullen, Douglas G Muench
BMC Cell Biology , 2005, DOI: 10.1186/1471-2121-6-40
Abstract: We demonstrate that MFP is an authentic microtubule-binding protein, as it localized to the cortical microtubule array in vivo, in addition to its expected targeting to the peroxisome matrix. MFP does not, however, interact with the three mitotic microtubule arrays. Microtubule co-sedimentation assays of truncated versions of MFP revealed that multiple microtubule-binding domains are present on the MFP polypeptide. This indicates that these regions function together to achieve high-affinity binding of the full-length protein. Real-time imaging of a transiently expressed green fluorescent protein-MFP chimera in living plant cells illustrated that a dynamic, spatial interaction exits between peroxisomes and cortical microtubules as peroxisomes move along actin filaments or oscillate at fixed locations.Plant MFP is associated with the cortical microtubule array, in addition to its expected localization in the peroxisome. This observation, coupled with apparent interactions that frequently occur between microtubules and peroxisomes in the cell cortex, supports the hypothesis that MFP is concentrated on microtubules in order to facilitate the regulated import of MFP into peroxisomes.Peroxisomes are single-membrane-bound organelles that lack a genome and, therefore, must import their entire complement of constituent proteins. All proteins that are targeted to the peroxisome are synthesized on free polyribosomes in the cytosol and are imported post-translationally. Several distinct import pathways exist for membrane and matrix proteins (reviewed in [1]). For example, peroxisomal membrane proteins can be targeted either directly to the peroxisome from their sites of synthesis in the cytosol, or indirectly to peroxisomes via the endoplasmic reticulum ([2,3], and references therein). On the other hand, peroxisomal matrix proteins can be imported from the cytosol in their fully-folded conformation and as oligomeric protein complexes. Two types of peroxisomal matrix protein imp
RGD-conjugated gold nanorods induce radiosensitization in melanoma cancer cells by downregulating αvβ3 expression
Xu WC, Luo T, Li P, Zhou CQ, Cui DX, Pang B, Ren QS, Fu S
International Journal of Nanomedicine , 2012, DOI: http://dx.doi.org/10.2147/IJN.S28314
Abstract: onjugated gold nanorods induce radiosensitization in melanoma cancer cells by downregulating αvβ3 expression Original Research (3276) Total Article Views Authors: Xu WC, Luo T, Li P, Zhou CQ, Cui DX, Pang B, Ren QS, Fu S Published Date February 2012 Volume 2012:7 Pages 915 - 924 DOI: http://dx.doi.org/10.2147/IJN.S28314 Received: 16 November 2011 Accepted: 29 December 2011 Published: 27 February 2012 Wencai Xu1, Teng Luo2, Ping Li1, Chuanqing Zhou2, Daxiang Cui3, Bo Pang4, Qiushi Ren4, Shen Fu1 1Department of Radiation Oncology, Shanghai Sixth People's Hospital, 2School of Biomedical Engineering, and 3National Key Laboratory of Nano/Micro Fabrication Technology, Key Laboratory for Thin Film and Microfabrication of Ministry of Education, Institute of Micro-Nano Science and Technology, Shanghai Jiao Tong University, Shanghai, 4Department of Biomedical Engineering, College of Engineering, Peking University, Beijing, People's Republic of China Background: Melanoma is known to be radioresistant and traditional treatments have been intractable. Therefore, novel approaches are required to improve the therapeutic efficacy of melanoma treatment. In our study, gold nanorods conjugated with Arg-Gly-Asp peptides (RGD-GNRs) were used as a sensitizer to enhance the response of melanoma cells to 6 mV radiation. Methods and materials: A375 melanoma cells were treated by gold nanorods or RGD-GNRs with or without irradiation. The antiproliferative impact of the treatments was measured by MTT assay. Radiosensitizing effects were determined by colony formation assay. Apoptosis and cell cycle data were measured by flow cytometry. Integrin αvβ3expression was also investigated by flow cytometry. Results: Addition of RGD-GNRs enhanced the radiosensitivity of A375 cells with a dose-modifying factor of 1.35, and enhanced radiation-induced apoptosis. DNA flow cytometric analysis indicated that RGD-GNRs plus irradiation induced significant G2/M phase arrest in A375 cells. Both spontaneous and radiation-induced expressions of integrin αvβ3 were downregulated by RGD-GNRs. Conclusion: Our study indicated that RGD-GNRs could sensitize melanoma A375 cells to irradiation. It was hypothesized that this was mainly through downregulation of radiation-induced αvβ3, in addition to induction of a higher proportion of cells within the G2/M phase. The combination of RGD-GNRs and radiation needs further investigation.
A sandwich-type DNA electrochemical biosensor for hairpin-stem-loop structure based on multistep temperature-controlling method
Hong GL, Liu YH, Chen W, Weng SH, Liu QC, Liu AL, Zheng DX, Lin XH
International Journal of Nanomedicine , 2012, DOI: http://dx.doi.org/10.2147/IJN.S35177
Abstract: sandwich-type DNA electrochemical biosensor for hairpin-stem-loop structure based on multistep temperature-controlling method Original Research (1490) Total Article Views Authors: Hong GL, Liu YH, Chen W, Weng SH, Liu QC, Liu AL, Zheng DX, Lin XH Published Date September 2012 Volume 2012:7 Pages 4953 - 4960 DOI: http://dx.doi.org/10.2147/IJN.S35177 Received: 20 June 2012 Accepted: 25 July 2012 Published: 14 September 2012 Guolin Hong,1,2,* Yinhuan Liu,1,* Wei Chen,3,5 Shaohuang Weng,3,5 Qicai Liu,4 Ailin Liu,3,5 Daoxin Zheng,1 Xinhua Lin,3,5 1Department of Laboratory Medicine, The Fuzhou Second Affiliated Hospital of Xiamen University, Fuzhou, China; 2Department of Laboratory Medicine, Medical Technology and Engineering College of Fujian Medical University, Fuzhou, China; 3Department of Pharmaceutical Analysis, Pharmacy College of Fujian Medical University, Fuzhou, China; 4Department of Laboratory Medicine, The First Affiliated Hospital of Fujian Medical University, Fuzhou, China; 5Nano Medical Technology Research Institute, Fujian Medical University, Fuzhou, China *Guolin Hong and Yinhuan Liu contributed equally to the present study Abstract: A highly sensitive and selective method for amplified electrochemical detection for hairpin-stem-loop structured target sequences was developed based on the temperature regulation of DNA hybrids on a sandwich-type electrochemical DNA sensor. Multistep hybridization was applied to promote the hybridization efficiency of each section of sandwich structure. The results showed that both multistep and temperature-controlling hybridization techniques were both especially made to fabricate the sensor for the tendency of internal hybridization of target gene sequences. This strategy provides significantly enhanced hybridization efficiency and sequence specificity of electrochemical detection.
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