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Search Results: 1 - 10 of 191346 matches for " D Iya "
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Urinary Retention Caused by Foreign Body
N. K. Dakum, D. Iya
Nigerian Journal of Surgical Research , 2001,
Abstract: A 54-year-old man was referred from a private hospital with recurrent episodes of urinary tract infection and urinary retention, 18 months following transvesical prostatectomy for benign prostatic hyperplasia. A retained gauze embedding a stone was removed from the bladder neck at exploration. Adherence to sound surgical principle will avoid the hazards of retained gauze and other instruments. (Nig J Surg Res 2001; 3: 90 – 92) KEY WORDS: Retained Gauze, Prevention
Mass casualty management: Jos University Teaching Hospital experience
HC Nwadiaro, D Iya, SJ Yiltok, AT Kidmas
West African Journal of Medicine , 2003,
Abstract: Three experiences of management of mass casualties in Jos University Teaching Hospital were analysed. Classification into minor, moderate and major mass casualties was done using multiple criteria of number of casualties, number of doctors required to contain the situation, number of nurses and paramedical staff, degree of distruption of hospital services and time required to handle the immediate stabilisation of the casualties. The classification recognises a category called “regional disaster” and attempts to enunciate a principle of initiation, mobilisation and co-ordination of management of such disasters among hospitals and human and material resources within the region. It is envisaged that coalescence of “regional disaster preparedness” would from the bedrock of national ambulance services system.
Male breast malignancy in Jos University Teaching Hospital
AT Kidmas, BT Ugwu, AN Manasseh, D Iya, AS Opaluwa
West African Journal of Medicine , 2005,
Abstract: Background: Male breast malignancies are rare. Cancer of the male breast accounts for about 1% of all breast cancers. Poor level of awareness often results in late presentation and delayed diagnosis in our environment. Patients and Methods: A retrospective study of all cases of male breast cancer (MBC) managed in Jos University Teaching Hospital over a 17-year period (January 1987-December 2003.) Results: A total of 302 cases of breast malignancies were managed over the study period. Twenty-six (8.6%) of these were males giving a male:female ratio of 1:10.6. The ages of the 26 MBC cases ranged from 12 years to 85 years, with a mean of 57.9 years and median age of 67 years. The right breast was affected in 15 and the left in 11. Mean duration of symptoms before presentation was 6 months with a range of 3 months to 4 years. All the patients had history of breast lumps, 21 (80.8%) of which were painless. Skin ulceration and axillary node enlargement were present in 19(73.1%) and 24(92.3%) respectively. Five (19.2%) were stage II; 15(57.7%) stage III and 6(23.1%) stage IV. There were 23 (88.5%) carcinomas, 2 (7.7%) fibrosarcomas and a case of Hodgkin's lymphoma. Invasive ductal carcinoma was the most common histological type in 20 (76.9%) of all breast malignancy and 20 (87.0%) of all breast carcinomas. Modified radical mastectomy (mastectomy with axillary clearance with or without division of the pectoralis minor muscle) was done in 10(38.5%) patients. Two of these were fibrosarcomas. Simple mastectomy was done in 13 (50%) as toilet procedures for advanced disease. The only case of Hodgkin's lymphoma had chemotherapy. Bilateral orchidectomy (BO), Tamoxifen, chemotherapy and radiotherapy were offered in 7(26.9%), 13(50%), 17(65.4%) and 7(26.9%) patients respectively. Wound infection was the most common complication in 14(53.8%) patients. There was no case of hospital mortality. Conclusion: MBC accounts for 8.6% of all breast cancers in our centre. It affects elderly males. Late presentation with advanced disease and ulceration is a common feature in our environment.
Delayed presentation of blunt traumatic diaphragmatic hernia: A case report
AT Kidmas, D Iya, ES Isamade, E Ekedigwe
Nigerian Journal of Surgical Research , 2005,
Abstract: Blunt traumatic diaphragmatic rupture is an uncommon but severe problem that is usually seen in poly-traumatized patients. Diagnosis is often difficult resulting in delayed presentation and increased morbidity. We report a case of blunt traumatic diaphragmatic hernia in a 39-year-old man presenting 10 years after the initial abdomino-thoracic injury sustained in a road traffic accident. He had herniation of the spleen and stomach. Through a left thoracotomy, the herniated organs were reduced and diaphragmatic defect closed with interrupted nylon sutures. A high index of suspicion would minimize the morbidity and mortality associated with delayed diagnosis.
Spontaneous scrotal faecal fistula in a neonate: report of a case
LB Chirdan, AF Uba, D Iya, NK Dakum
Nigerian Journal of Surgical Research , 2004,
Abstract: A 21 day old boy with spontaneous scrotal faecal fistula following a neglected strangulated right inguinal hernia is reported. He had necrotizing fasciitis of the right scrotum with sparing of the testis. He successfully had debridement, herniotomy and bowel resection with end-to-end anastomosis. This is a rare occurrence in infants and seems to result from late presentation. Health education coupled with early referral and prompt repair of inguinal hernia in neonates and infants would reduce this complication.
Prostate specific antigen in Africans: a study in Nigerian men
D Iya, S Chanchani, J Belmonte, D Morris, RH Glew, DJA Van der Jagt
Nigerian Journal of Surgical Research , 2003,
Abstract: Background: Since the reference range of prostate specific antigen (PSA) that are used for the screening, diagnosis and management of prostate disease are based on studies of PSA range in Caucasians and African-Americas, they may not be applicable to other ethnicities, especially indigenous African populations. Methods: In a hospital-based study, we measured total PSA levels using an immunoassay (DSL-10-9700 Active Enzyme-Linked Immunosorbent Assay, Webster, TX) in patients with prostate disease (n = 48) and age-matched controls (n = 64). Results: The mean total PSA value for healthy Nigerians was significantly lower than the established values for African-Americans (2.22+/- 2.90 ng/ml versus 7.56+/- 1.11 ng/ml, respectively). PSA values in the controls did not increase with age. Severity of symptoms was not age-dependent; however, PSA levels did increase with severity of symptoms (p = 0.002). Conclusion: The PSA range of healthy Nigerian men were significantly lower than those of African-American or Caucasian men. This underscores the need for a population-specific reference range for African men. Key Words: Prostate specific antigen, benign prostatic hyperplasia, prostate cancer Nigerian Journal of Surgical Research Vol.5(1&2) 2003: 114-119
Ring Entrapment of the Finger in a Psychiatric Patient
V. M. Ramyil, N. K. Dakum, L. N. Ayuba, D. Iya
Nigerian Journal of Surgical Research , 2001,
Abstract: Ring entrapment of the finger is an uncommon occurrence in our environment and is usually amenable to conservative treatment by removal of the entrapped ring. Gangrene of the affected digit is rare. This is a report of a 57-year-old schizophrenic who developed ulceration, severe oedema and gangrene of the right middle finger following entrapment by a ring like motor spare part. Disarticulation at the metacarpophalangeal joint was necessary. The gangrene was possibly due to a combination of severe oedema, infection or a Raynaud's like phenomenon. (Nig J Surg Res 2001;3:37-40) KEY WORDS: Ring, finger entrapment, gangrene, psychiatric illness
Urological Tumours in Jos University Teaching Hospital, Jos, Nigeria
B. M. Mandong, D. Iya, P.O. Obekpa, K. S. Orkar
Nigerian Journal of Surgical Research , 2000,
Abstract: This is a hospital based retrospective histopathological study of urological tumours in 10 years. Specimens consisted of all surgical excisions, trucut and fine needle biopsies of kidney, prostate, urinary bladder, testis and penis. Urological tumours accounted for 11.45% of all malignant tumours during the period of study. Prostate cancer accounted for 44.1%, urinary bladder 31.7%, kidney 17.3%, testis 5.8% and penis 1%. The study also showed that urinary bladder tumour and malignant tumours of the kidney were found predominantly in males in the ratio of 3:1. There was a high rate of prostate cancer, changing pattern of urinary bladder cancer from squamous cell carcinoma to transitional cell carcinoma. This finding is in contrast to what has been reported in some African countries. Urological tumours appear common in our surgical specimens and constitute significant proportion of malignancies in Jos University Teaching Hospital. This study forms the bases for further evaluation and epidemiological studies (Nig J Surg Res 2000; 2:108-113) KEY WORDS: Urological tumours, prostate, urinary bladder, changing pattern
Taurocholate Binding Capacity and Water Holding Capacity of Some Wild Leafy Vegetables of Northern Nigeria
H.A. Umaru,S.A. Iya,W. Obidah,D. Dahiru
Pakistan Journal of Nutrition , 2010,
Abstract: Taurocholate binding capacity (TBC) and water holding capacity (WHC) of twelve wild leafy vegetables commonly consumed in northern Nigeria were studied. Taurocholate binding capacity varied between 17.36±2.58 to 31.02±1.21mg/g. Results obtained showed that Celtis africana had the highest taurocholate binding value of 31.02±1.21 mg/g followed by Hibiscus cannabimis (30.02±1.23) and Balanite aegyptiaca (30.12±3.23mg/g). The lowest taurocholate binding capacity value was observed in Apuim gravealens (21.73±0.25mg/g). While the highest water holding capacity value was observed in Celtis africana (2.24±0.28mg/g), closely followed by Balanite aegyptiaca (2.08±0.11mg/g) and Moringa oleifera (1.88±0.13mg/g). Corchorus oloitoms, Solanium nigrum and Mormodica basalmina had the lowest water holding capacity value (1.02±0.04, 1.21±0.01 and 1.27±0.05mg/g respectively). Thus indicating that these wild vegetables contain high fiber and have the potential to reduce cholesterol considerably from the body and other related diseases.
Causal Modeling Using Network Ensemble Simulations of Genetic and Gene Expression Data Predicts Genes Involved in Rheumatoid Arthritis
Heming Xing,Paul D. McDonagh ,Jadwiga Bienkowska,Tanya Cashorali,Karl Runge,Robert E. Miller,Dave DeCaprio,Bruce Church,Ronenn Roubenoff,Iya G. Khalil,John Carulli
PLOS Computational Biology , 2011, DOI: 10.1371/journal.pcbi.1001105
Abstract: Tumor necrosis factor α (TNF-α) is a key regulator of inflammation and rheumatoid arthritis (RA). TNF-α blocker therapies can be very effective for a substantial number of patients, but fail to work in one third of patients who show no or minimal response. It is therefore necessary to discover new molecular intervention points involved in TNF-α blocker treatment of rheumatoid arthritis patients. We describe a data analysis strategy for predicting gene expression measures that are critical for rheumatoid arthritis using a combination of comprehensive genotyping, whole blood gene expression profiles and the component clinical measures of the arthritis Disease Activity Score 28 (DAS28) score. Two separate network ensembles, each comprised of 1024 networks, were built from molecular measures from subjects before and 14 weeks after treatment with TNF-α blocker. The network ensemble built from pre-treated data captures TNF-α dependent mechanistic information, while the ensemble built from data collected under TNF-α blocker treatment captures TNF-α independent mechanisms. In silico simulations of targeted, personalized perturbations of gene expression measures from both network ensembles identify transcripts in three broad categories. Firstly, 22 transcripts are identified to have new roles in modulating the DAS28 score; secondly, there are 6 transcripts that could be alternative targets to TNF-α blocker therapies, including CD86 - a component of the signaling axis targeted by Abatacept (CTLA4-Ig), and finally, 59 transcripts that are predicted to modulate the count of tender or swollen joints but not sufficiently enough to have a significant impact on DAS28.
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