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Search Results: 1 - 10 of 139583 matches for " Corin K. Nishimura "
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Computational Analysis of Theacrine, a Purported Nootropic and Energy-Enhancing Nutritional Supplement  [PDF]
Bradley O. Ashburn, Diana J. Le, Corin K. Nishimura
Computational Chemistry (CC) , 2019, DOI: 10.4236/cc.2019.71002
Herein is the first reported conceptual density functional theory (DFT) investigation of the purine alkaloid theacrine and the comparison of quantum chemical properties to the closely related stimulant caffeine. DFT global chemical reactivity descriptors (chemical hardness/softness, chemical potential/ electronegativity, and electrophilicity) and local reactivity descriptors (Fukui functions and dual descriptor) were calculated for both compounds using Spartan ‘16 software. All calculations were carried out at the B3LYP/6-31G* level of theory. Reactivity analysis of the Fukui dual descriptor calculations reveals sites of nucleophilic and electrophilic attack. The results provide a solid chemical foundation for understanding how theacrine interacts with cellular systems.
Hyperbilirubinaemia after major thoracic surgery: comparison between open-heart surgery and oesophagectomy
Kikumi K Hosotsubo, Masaji Nishimura, Shinya Nishimura
Critical Care , 2000, DOI: 10.1186/cc691
Abstract: Hyperbilirubinaemia was detected in 51% of the open-heart surgery patients (n = 133) and in 64% in the oesophagectomy group (n = 74). The incidence of hyperbilirubinaemia was significantly related to the duration of surgery (P< 0.05). In the open-heart surgery group, duration of surgery was 465 ± 24 min for the patients without hyperbilirubinaemia and 571 ± 26 min for the patients with hyperbilirubinaemia. In the oesophagectomy group, the procedure durations were 415 ± 17 min and 493 ± 20 min, respectively. The overall mortality rate was 8% in the open-heart surgery group; the rate was 12% in those with hyperbilirubinaemia, but 5% in those without hyperbilirubinaemia. No members of the oesophagectomy group died, with or without hyperbilirubinaemia. Infection significantly affected both the occurrence of hyperbilirubinaemia and mortality in the open-heart surgery group. In the subgroups from the open-heart surgery group, 5% (three out of 65) of those without hyperbilirubinaemia (or evidence of infection) died; of the patients with hyperbilirubinaemia, 3% (one out of 38) of those without infection died and 23% (seven out of 30) with detected infection died.After open-heart surgery and oesophagectomy, approximately half of the patients studied had higher levels of serum total bilirubin. Time spent in surgery was significantly related to the occurrence of hyperbilirubinaemia. Infection significantly affected mortality and total bilirubin levels after open-heart surgery. Control of infection plays a crucial role in the prevention of hyperbilirubinaemia and in reducing mortality.Researchers have reported rates of hyperbilirubinaemia after cardiac operations involving cardiopulmonary bypass (CPB) that range from approximately 5% [1] to 20% or even as high as 40% [2]. Hypoperfusion, haemodilution and other factors that reduce the delivery of oxygen to the liver or increase the bilirubin load are thought to cause postoperative hyperbilirubinaemia. Most reports, however, have
Urmuz, précurseur de l’Avant-garde roumaine
Corin Braga
Synergies Roumanie , 2007,
Abstract: Urmuz est considéré par les historiens contemporains de la littérature comme le précurseur de l’Avant-garde roumaine. Dans l’article, l’auteur essaye de faire une psychocritique de la littérature d’Urmuz, de cerner les mécanismes psychanalytiques qui pourraient expliquer la paralogique de ses récits.
Norman Manea et les univers concentrationnaires
Corin Braga
Synergies Roumanie , 2010,
Abstract: Norman Manea est un écrivain roumain, prosateur et romancier, naturalisé aux Etats-Unis. Ses livres, traduits dans plus de vingt langues, s’apparentent par leur vision et leur thématique à ceux de Herta Müller, écrivain allemand d’origine roumaine, lauréate du prix Nobel en 2009, reflétant la persécution de l’individu sous un régime totalitaire. Juif roumain, Norman Manea a subi deux univers concentrationnaires qui se sont succédé en Roumanie au XXe siècle, le fascisme, pendant la deuxième guerre mondiale, et le communisme, instauré après l’invasion soviétique. Cette étude analyse le mode de transfiguration esthétique des traumas biographiques présentés dans quelques-uns des romans les plus connus de Norman Manea, Octombrie, ora opt (1981), Plicul negru (1986), Despre clovni (1997).
Archetipo versus anarchetipo
Corin Braga
LEA : Lingue e Letterature d'Oriente e d'Occidente , 2013,
Abstract: In this paper, I try to coin a new concept: the anarchetype. The anarchetype is, from a formal point of view, a dissolute or exploded archetype. Generally speaking, archetypal literary works have a structure, a logos, a homogenous pattern which gives them a global meaning. This pattern could be inherited from the cultural tradition (O’Neill revisiting the Electra legend, James Joyce rewriting the Odyssey, etc.), or generated by the genre during its evolution (the Bildungsroman, etc.). Symmetrically, anarchetypal works or bodies of texts appear as anarchical and chaotic. They do not accept a central organizing meaning, they evolve on different contradictory levels. Using a cosmological metaphor, I would compare the archetype with a solar system, in which the planets harmoniously move around the central sun, while an anarchetype is similar to a galactic cloud of dust before its accretion in a solar system or resulting from the explosion of a supernova. The complementary terms archetype/anarchetype partially recall Deleuze’s opposition between “root” and “rhizomes”.
”Imagination”, ”imaginaire”, ”imaginal” Three concepts for defining creative fantasy
Corin Braga
Journal for the Study of Religions and Ideologies , 2007,
Abstract: This paper comparatively presents three notions related to the concept of creative fantasy. These three terms (”imagination”, ”imaginaire”, ”imaginal”) have been developed by the French school of research on the imagination (“recherches sur l’imaginaire”), which is little known in the Anglo-Saxon academic field. As such, the terms don’t even have convenient translations and linguistic equivalents. Briefly, imagination is fantasy conceived as a combinatory faculty of the psyche. French rationalistic “philosophes” saw it as a misleading and rather weakly creative ability. ”L’imaginaire” is the resourceful and inventive aspect of fantasy, as conceived by the Romantics and then theorized by psychoanalysis and contemporary French philosophers. ”L’imaginal”, or ”mundus imaginalis” is a concept defined by Henry Corbin in order to designate fantasies as self-sustained, ontological beings.
Psychoanalytical Geography
Corin Braga
Journal for the Study of Religions and Ideologies , 2008,
Abstract: The constructing principles of ancient cartography were for most of the time non-mimetic and non-empirical, so that the maps build on their basis had a most fantastic shape. We could safely call this kind of non-realistic geography – symbolic geography. In this paper, I focus on the psychological projections that shaped the form of pre-modern maps. The main epistemological instrument for such an approach is offered by Freudian psychoanalysis and Jungian analytical psychology. In ”psychoanalytical geography”, Freudian schemes of interpretation (the oral, anal and genital stages of evolution) are put to work for explaining the complex mechanisms of identification and transference at work in ancient cartography.
Carlos Castaneda: The Uses and Abuses of Ethnomethodology and Emic Studies
Corin Braga
Journal for the Study of Religions and Ideologies , 2011,
Abstract: Carlos Castaneda’s books and his New Age shamanistic religion raise, beyond the controversy regarding the counterfeit character of his ethnographic narrative and charlatanism, several methodological problems. Educated within the emerging paradigm of emic studies and ethnomethodoly of the 1960s, Castaneda used it in order to set a very clever methodological trap: Can an ethnologist and historian of religions discard a religious movement on account that its initiator is a charlatan or, at best, an enlightened or self-deluded individual? In order to tackle this dilemma, in this article I successively rally several methods and hermeneutics: reader-response theory, phenomenological anthropology, ethnomethodology and emic studies, psychoanalysis, fictional worlds theory, and “make believe / make belief” theatrical theory.
A new approach to the complex-action problem and its application to a nonperturbative study of superstring theory
K. N. Anagnostopoulos,J. Nishimura
Physics , 2001, DOI: 10.1103/PhysRevD.66.106008
Abstract: Monte Carlo simulations of a system whose action has an imaginary part are considered to be extremely difficult. We propose a new approach to this `complex-action problem', which utilizes a factorization property of distribution functions. The basic idea is quite general, and it removes the so-called overlap problem completely. Here we apply the method to a nonperturbative study of superstring theory using its matrix formulation. In this particular example, the distribution function turns out to be positive definite, which allows us to reduce the problem even further. Our numerical results suggest an intuitive explanation for the dynamical generation of 4d space-time.
New Physics Prospects in Mixing and CP Violation at Belle II
K. Nishimura,for the Belle II Collaboration
Physics , 2012,
Abstract: The Belle II experiment at the SuperKEKB electron-positron collider will provide a large sample of charm mesons in addition to its primary goal of B meson production. The large data sample and wide variety of accessible D meson decay modes in a clean experimental environment provide sensitivity to new physics via D meson mixing and CP violation measurements. This contribution briefly describes selected components of the upgrade from Belle to Belle II and KEKB to SuperKEKB, and some prospects for new physics searches in the areas of charm mixing and CP violation.
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