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Search Results: 1 - 10 of 4713 matches for " Complications "
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Chronic Graft versus Host Disease after Allogeneic Bone Marrow Transplantation; An Analysis of Incidence and Risk Factors.
Ghavamzadeh A,Alimoghaddam K,Bahar B,Foroughi F
International Journal of Hematology-Oncology and Stem Cell Research , 2004,
Abstract: Chronic graft versus host disease (cGVHD) is one of the most serious potential complications of"nallogeneic bone marrow transplantation."nStudy design and method: We analyzed the incidence of cGVHD and its associated risk factors in a group of 161"nIranian recipients of HLA-identical sibling transplants, with at least 90 days post-transplantation survival. In the"nmajority of cases (n=73), cGVHD occurred in the first year after the transplant (median 273 days). The actual"nprobability of cGVHD within 1 year was 45.3±7% (CI 95%)."nResults: In a univariate analysis, the most important risk factor was the type of transplant. Peripheral blood stem cell"ntransplants (PBSCT) showed a significant increase in cGVHD compared with bone marrow transplants (BMT)"n(RR=2.34, p<0.001). In addition, male recipients were at a greater risk than female recipients (RR=2.08, p=0.004)."nOther risk factors were the presence of prior acute GVHD (RR=2.37, p=0.04) and the previous acute GVHD grade"n(p=0.03); The probabilities of cGVHD in patients with grade 0, Ι, Ι , ΙΙΙ, ΙV acute GVHD were 24%, 44.7%, 42.6%,"n56.8%, 64.3%, respectively."nConclusion: In a multivariate analysis, the only independent predictive factors for the development of cGVHD were the type of transplant (PBSC>BM, p<0.001) and male recipient (p=0.005). The survival rate was 88.8% and there was no significant difference in the probability of survival between BPSCT vs BMT (93.8% vs 86.6%, p=0.5).
Pregnancy complications and outcomes in women with epilepsy  [PDF]
Mirzaei Fatemeh, Ebrahimi B. Nazanin
Open Journal of Obstetrics and Gynecology (OJOG) , 2012, DOI: 10.4236/ojog.2012.23047
Abstract: Epilepsy is the most common serious neurological disorder. This is prospective study to investigate whether women with epilepsy have an increased risk of fetal and maternal complications during pregnancy. In this descriptive cross-sectional study, 50 pregnant women who were presented for delivery at Afzalipour Hospital, Kerman, Iran during 2003 to 2009 were assessed. The groups were compared using the Student’s t-test, and one-way-ANOVA for continuous variables and the chisquare test (or Fisher’s exact test if required) for categorical variables. P values of 0.05 or less were considered statistically significant. All the statistical analyses were performed using SPSS version 13 (SPSS Inc, Chicago, IL, USA) for Windows.In 32 (64%) of cases no fetal complication was found, in 5 cases (10.0%) intrauterine growth retardation (IUGR), in 2 cases (4.0%) post-term labor, in 2 cases (4.0%) fetal distress and in 9 cases (18.0%) preterm labor were found. In 15 patients (30.0%) no maternal complication was found; in 2 cases (4.0%) pregnancy induced hypertension (PIH), in 12 cases (24.0%) preterm labor , in 4 cases (8.0%) bleeding, in 14 cases (28.0%) premature rupture of the membranes (PROM) and in 3 cases (6.0%) other complications were detected. Given these findings and previous studies, it seems that epileptic women required more care during pregnancy and the rate of maternal, fetal and obstetrical complications are relatively high among them.
Relationship between prenatal care and the outcome of pregnancy in low-risk pregnancies  [PDF]
Tehereh Ashraf-Ganjoei, Fatemeh Mirzaei, Fatemeh Anari-Dokht
Open Journal of Obstetrics and Gynecology (OJOG) , 2011, DOI: 10.4236/ojog.2011.13019
Abstract: Introduction: This study was conducted to evaluate the relationship between prenatal care and outcome of pregnancy. Method: This is a cross-sectional study on 210 pregnant women referring to Afzalipour Hospital for their labor, consisting of 140 women with adequate care and 70 with inadequate care. The outcome of pregnancy for mother and newborn was compared between the two groups. Data were analyzed using SPSS software version 15. P value ≤ 0.05 was considered as significant and the power of statistical test was 80%. Findings: The findings indicate that the age of women with inadequate care was lower compared to those receiving adequate care (p = 0.003). Furthermore, women with inadequate care had lower education (p = 0.00007) and their prenatal care started in more advanced gestational ages (p = 0.0003). Neonates born to women with inadequate care tended to have lower birth weights (p = 0.05) and higher rates of admission to NICU (p = 0.02). Conclusion: Our findings indicate that women with lower age and education received less prenatal care and adequate prenatal care results in better birth weights and decreased rate of admission in NICU.
Fatal Complications and Early Death after Surgical Treatment of Lung Cancer in 2000 and 2010. A Population Based Study  [PDF]
Hans Rostad
Surgical Science (SS) , 2013, DOI: 10.4236/ss.2013.41019

In the year 2000 lung cancer was operated in 349 patients in Norway, in 2010 the number was 461. In the first period fatal surgical hemorrhage occurred in eight patients, in four of them peroperatively. Postoperative hemorrhage occurred in four patients in the year 2000 and in two in 2010. Ten patients died intra- or postoperatively in the two periods which is a mortality rate within 30 days after surgery of 4.3% in the first and 1.1% in the second period. Pneumonectomy was performed in 34 patients in 2000 and eight in 2010, respectively. Altogether 19 patients died within six months after surgery without having experienced surgical complications. Pneumonectomy should not be performed in elderly and debilitated persons.

Impact of obesity and diabetes on arthritis: An update  [PDF]
Rajesh Pandey, Narendra Kumar, Seema Paroha, Ram Prasad, Mukesh Yadav, Shalini Jain, Hariom Yadav
Health (Health) , 2013, DOI: 10.4236/health.2013.51019

The incidence of obesity and diabetes has been increased with alarming rate in recent years and became a common problem around the globe including developing as well as in developed countries with incalculable social costs. Obesity and type 2 diabetes are two common co-morbidities occur together. Obesity and diabetes is closely associated with many diseases, osteoarthritis, hypertension, certain form of cancer, sleep-breathing disorders and coronary heart disease. Impacts of obesity and diabetes (insulin resistance) on arthritis have been seen in patients that we associated with combination of various factors like increased availability of high-energy foods, genetic susceptibility and decreased physical activity in modern society. Arthritis is becoming pandemic around the globe and its occurrence with obesity and diabetes has been observed more common than ever. Combination of these two chronic conditions makes these diseases more vulnerable for human health. Till now very limited information is established about the pathological and mechanistic correlation among these health ailments. In this review article we aimed to survey the literature covering the influence of obesity and diabetes on arthritis pathology and tried to establish correlation with these diseases.

Complications of venepuncture  [PDF]
Omiepirisa Yvonne Buowari
Advances in Bioscience and Biotechnology (ABB) , 2013, DOI: 10.4236/abb.2013.41A018

Venepuncture is the commonest procedure performed in health care settings. A review of literature and search on complications of venepuncture and blood collection. This procedure is without complications, which sometime can be fatal. Complications that can arise from venepuncture include haematoma formation, nerve damage, pain, haemaconcentration, extravasation, iatrogenic anaemia, arterial puncture, petechiae, allergies, fear and phobia, infection, syncope and fainting, excessive bleeding, edema and thrombus.

Excellent femoral outcomes when all access attempts and closure devices are performed by experienced cardiologists  [PDF]
Kevin S. Kang, Quentin Orlando, Robert Maholic, Richard Petrella, Gurjaipal S. Kang
World Journal of Cardiovascular Diseases (WJCD) , 2013, DOI: 10.4236/wjcd.2013.39089

Femoral access is considered less safe for access site complications than the radial access. Cardiovascular procedures have not been studied taking operator experience, defined as American Board of Internal Medicine, Interventional Cardiology certification or equivalent qualification in another country, into account. We hypothesize that the procedural results are operator dependent and excellent results are obtained when procedures are performed by experienced operators. Femoral access is higher risk than radial access based on American College of Cardiology (ACC) guidelines. Femoral access is less forgiving, as opposed to radial, as it is an end-artery, lacks easy compressibility and is more likely to cause morbidity when injured. Hence, radial is recommended over the femoral approach according to ACC practice guidelines. These guidelines are often based on the randomized studies from academic centers where trainees, with variable arterial access experience, perform the initial access stick and arterial closure device deployment. Methods: We performed a single center retrospective review of 32,446 consecutive patients undergoing invasive cardiovascular procedures done from the femoral approach using American College of Cardiology/National Cardiovascular Data Registry (ACC/NCDR) from January 1, 2006 to June 30, 2013. Only experienced operators performed the actual access site stick and the reminder of the invasive procedure. Results: Total bleeding and vascular complications were less than 1%. We define outcomes as excellent if the total bleeding and vascular complication risk is less than 1% based on previous studies discussed in the ACC guidelines. Conclusion: Excellent outcomes can be obtained from the femoral access if experienced cardiologists perform the procedure. Hence, radial arterial access over the femoral access may be selectively rather than universally recommended considering the possibility of varying level of femoral access expertise of different practices.


Etiology of renal failure and peritoneal dialysis complications in Isfahan  [PDF]
Soheila Mojdeh, Shirin Karimi, Ali Mehrabi, Soheila Bakhtiari
Health (Health) , 2013, DOI: 10.4236/health.2013.510229

Introduction: Worldwide specific diseases are jeopardizing people’s health in the world as well as in Iran. Chronic renal failure as a developed and irreversible failure is usually progressive. End Stage Renal Disease (ESRD) is a situation when renal function is not sufficient to preserve one’s life leading to acute uremia resulting in dialysis and/or kidney transplantation for the patients. Although dialysis methods bring about complications for the patients, peritoneal dialysis is relatively cost-effective and more convenient to survive. The present study aimed to investigate (the) Etiologic factor of renal failure and imposed complications of peritoneal dialysis in the patients of Isfahan Alzahra hospital. Materials and Methods: It was a cross-sectional descriptive study conducted on 67 patients in Isfahan Peritoneal Dialysis Center. The data from the patients were collected through a two-section questionnaire whose first section was allocated to demographic information and the second part was related to the disease and complications of peritoneal dialysis. The collected data were analyzed by SPSS version 18. Results: The findings showed that there were 39 (58%) males and 28 (42%) females. Mean age of the subjects was 48 (18.8) years old. Regarding marital status, 65% were married and 35% were single. Considering complications, 28 subjects (53.5%) had infectious complications while 24 subjects (46.2%) had non-infectious complications. The highest frequency in etiologic factor of renal failure was diabetes mellitus in 29 subjects (43.9%) and the lowest for polycystic kidney in 2 subjects (3%); in addition, hypertension was observed in 51 subjects (77.3%). Discussion: The most frequent and important complication of peritoneal dialysis catheters is infection, whic

Ocular Complications of Strabismus Surgery  [PDF]
Nazife Sefi Yurdakul, Feray Ko?
Surgical Science (SS) , 2014, DOI: 10.4236/ss.2014.59064

Background: To evaluate ocular complications of strabismus surgery at the Department of Strabismus and Neuroophthalmology in our clinic. Methods: The medical records of patients who underwent strabismus surgery between March 1999 and February 2013 were retrospectively reviewed. Patients with minor ocular complications such as wound irregularities, conjunctivitis, subconjunctival hemorrhage, and less than six-month follow-up periods were excluded from the study. Employed strabismus surgeries included recessions, resections, muscle advancements, inferior oblique myectomies, and muscle transpositions. Results: Our case series are comprised of 1468 patients who underwent strabismus surgery. The ages of the patients ranged from 6 to 80 years. Recognized primary ocular complications were noted in eight patients (0.5%). Scleral perforation with retinal break was observed in one myopic patient during retrobulbar anesthesia. Medial rectus rupture occurred during medial rectus recession in one patient with chronic complete sixth nerve palsy. Conjunctival cyst occured postoperatively in one patient with partially refractive accommodative esotropia who had bilateral medial rectus recession. Corneal dellen developed postoperatively in five patients with exotropia. Conclusion: Ocular complications of strabismus surgery are usually treatable. Damage to ocular structures can be prevented by meticulous surgical approach. Close postoperative follow-up is required in all cases.

Diabetes Complications and Associated Factors in Type 2 Diabetic Patients in Cotonou  [PDF]
Fran?ois Djrolo, No?l M. Para?so, Oumou Diarra, Michel Makoutode
Journal of Diabetes Mellitus (JDM) , 2014, DOI: 10.4236/jdm.2014.44043
Abstract: Long-term complications are the main sources of morbidity and mortality in diabetic patients. Aims: The aims of the study were to determine the rate of long-term complications in type 2 diabetic patients and to identify factors associated to these complications. Patients and method: Successive type 2 diabetic patients attending the diabetic center were submitted to a questionnaire and to clinical examination. Data were completed by consulting their medical reports. Chi square test was used for statistical analysis. Results: In 150 diabetic patients included in the study, the global rate of complications was 78.0%. Specific rate for itch complication investigated was 57.7% for peripheral neuropathy, 75.0% for erectile dysfunction, 20.0% for nephropathy, 36.6% for retinopathy, 40% for macroangiopathy and 8.0% for foot ulcer. Factors significantly associated with high rate of complications were age above or equal to 50 years (p = 0.001), the male gender (p = 0.000), high blood pressure (p = 0.0001), the absence of familial history of diabetes (p = 0.02), the duration of the disease above 5 years (p = 0.001) and high HbA1c level (p = 0.001). Conclusion: This study revealed that type 2 diabetic patients followed up in the diabetic center in Cotonou showed a high rate of chronic complications which often occurred in a younger age than in developed countries. Numerous socio-demographic and biological factors were significantly associated with the high rate of complications.
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