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Search Results: 1 - 10 of 36281 matches for " Ci-Hong Liou "
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Single or in Combination Antimicrobial Resistance Mechanisms of Klebsiella pneumoniae Contribute to Varied Susceptibility to Different Carbapenems
Yu-Kuo Tsai, Ci-Hong Liou, Chang-Phone Fung, Jung-Chung Lin, L. Kristopher Siu
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0079640
Abstract: Resistance to carbapenems has been documented by the production of carbapenemase or the loss of porins combined with extended-spectrum β-lactamases or AmpC β-lactamases. However, no complete comparisons have been made regarding the contributions of each resistance mechanism towards carbapenem resistance. In this study, we genetically engineered mutants of Klebsiella pneumoniae with individual and combined resistance mechanisms, and then compared each resistance mechanism in response to ertapenem, imipenem, meropenem, doripenem and other antibiotics. Among the four studied carbapenems, ertapenem was the least active against the loss of porins, cephalosporinases and carbapenemases. In addition to the production of KPC-2 or NDM-1 alone, resistance to all four carbapenems could also be conferred by the loss of two major porins, OmpK35 and OmpK36, combined with CTX-M-15 or DHA-1 with its regulator AmpR. Because the loss of OmpK35/36 alone or the loss of a single porin combined with blaCTX-M-15 or blaDHA-1-ampR expression was only sufficient for ertapenem resistance, our results suggest that carbapenems other than ertapenem should still be effective against these strains and laboratory testing for non-susceptibility to other carbapenems should improve the accurate identification of these isolates.
Synthesis and Characterization of Novel Hybrid Poly(methyl methacrylate)/Iron Nanowires for Potential Hyperthemia Therapy  [PDF]
Huey-Wen Liou, Hong-Ming Lin, Yeu-Kuang Hwu, Wen-Chang Chen, Wei-Jen Liou, Li-Chung Lai, Wei-Syuan Lin, Wen-An Chiou
Journal of Biomaterials and Nanobiotechnology (JBNB) , 2010, DOI: 10.4236/jbnb.2010.11007
Abstract: Externally applied magnetic fields have been used in this study to fabricate bamboo-like iron nanowires with or without a layer of Poly(methyl methacrylate) (PMMA). The hybrid PMMA/Fe nanowires were synthesized via hard X-ray synchrotron radiation polymerization with various treatment parameters. The results of XRD show that an oxide layer formed on the surface of the iron nanowires. The Fe2O3 and Fe3O4 phases coexist in the iron nanowires without X-ray irradiation. After X-ray irradiation, the Fe2O3 phase transformed into Fe3O4, which stabilized the iron nanowires. The results of XAS proved this phase transformation. TGA analysis confirmed the thermal properties and solid contents in these specimens. Their ferromagnetic behaviors were examined by magnetic hysteresis measurement, which indicated that the magnetic and structural properties of the nanowires can be manipulated by irradiation treatment. This may lead to a novel synthesis for iron nanowires that can be used in high thermal efficiency hyperthermia therapy.
The Development of Electricity Grid, Smart Grid and Renewable Energy in Taiwan  [PDF]
Hwa Meei Liou
Smart Grid and Renewable Energy (SGRE) , 2017, DOI: 10.4236/sgre.2017.86011
Abstract: The grid has played a vital role in the evolution of the electricity market; from traditional to smart grids; from fossil fuel power generated electricity grid connections to the integration of other renewable energy forms such as solar and wind power; the grid has played a key role in each step in Taiwan’s move towards energy transition. This study includes Taiwan’s construction of its transmission and distribution network, the recently passed newly revised version of the Electricity Act with its revisions to its transmission and distribution related content, and policies promoting the smart grid as well as issues that the renewable energy grid has raised in both the technical and legal aspects. Taiwan’s electricity supply system is made up of the northern, central and southern systems. The Transmission and distribution grid have been defined as a common carrier, maintaining state-owned monopoly. The smart grid has 6 main facets to promote, including smart generation and dispatch, smart transmission, smart consumers, smart grid electricity grid industry and the establishment of a smart grid environment. Due to the possible effects of the integration of renewable energy generated electricity, there is a vital need for the regulation of the grid’s management and skills.
Experimental Investigation of the Cross-Sensitivity and Size Effects of Polyvinylidene Fluoride Film Sensors on Modal Testing
Kuo-Chih Chuang,Chien-Ching Ma,Hong-Cin Liou
Sensors , 2012, DOI: 10.3390/s121216641
Abstract: Due to advantages such as light weight, flexibility, and low cost, polyvinylidene fluoride (PVDF) films have been widely used in engineering applications as sensors for detecting strain, pressure, or micro-force. However, it is known that PVDF strain sensors have strain cross-sensitivity in mutually orthogonal directions. Furthermore, the size of the PVDF film sensor would also affect the dynamic strain sensing performance. In this paper, to investigate the cross-sensitivity and size effects experimentally, we employ PVDF film sensors to perform dynamic measurements on a cantilever beam. Since the vibrations of the cantilever beam are excited by impacts of a steel ball, the induced highly repeatable transient responses contain a wide range of resonant frequencies and thus can be used to investigate both the size and cross-sensitivity effects of the PVDF film sensors in a dynamic sensing environment. Based on the experimental results of the identified resonant frequencies compared with results obtained from a strain gauge, finite element calculations, and theoretical predictions, suggestions for the use of the PVDF strain sensor in modal testing are given in this paper.
A Korpelevich-like Algorithm for Variational Inequalities
Zhitao Wu, Yonghong Yao, Yeong-Cheng Liou and Hong-Jun Li
Journal of Inequalities and Applications , 2013, DOI: 10.1186/1029-242X-2013-76
Abstract: A Korpelevich-like algorithm has been introduced for solving a generalized variational inequality. It is shown that the presented algorithm converges strongly to a special solution of the genaralized variational inequality.
Eric Liou
Eric Liou
Revista Dental Press de Ortodontia e Ortopedia Facial , 2009, DOI: 10.1590/s1415-54192009000500005
Color-neutral heavy particle production in nucleus-nucleus collisions in the quasi-classical approximation
Tseh Liou
Physics , 2012, DOI: 10.1016/j.nuclphysa.2012.11.005
Abstract: We use a diagrammatic approach to study color-neutral heavy particle production in nucleus-nucleus collisions in a quasi-classical approximation without small-$x$ evolution. In order to treat the two nuclei symmetrically, we use the Coulomb gauge which gives the appropriate light cone gauge for each nucleus. The resulting cross section is factorized into a product of two Weizs\"{a}cker-Williams gluon distributions of the two nuclei when the transverse momentum of the produced scalar particle is around the saturation momentum. We confirm our results in covariant gauge where the transverse momentum broadening of hard gluons can be described as a diffusion process. The transverse momentum factorization manifests itself in light cone gauge but not so clearly in covariant gauge.
A Yield-Driven Gridless Router
Qiang Zhou,Yi-Ci Cai,Duo Li,Xian-Long Hong,
Qiang Zhou
,Yi-Ci Cai,Duo Li,and Xian-Long Hong

计算机科学技术学报 , 2007,
Abstract: A new gridless router to improve the yield of IC layout is presented.The improvement of yield is achieved by reducing the critical areas where the circuit failures are likely to happen.This gridless area router benefits from a novel cost function to compute critical areas during routing process,and heuristically lays the patterns on the chip area where it is less possible to induce critical area.The router also takes other objectives into consideration,such as routing completion rate and nets length.It takes advantage of gridless routing to gain more flexibility and a higher completion rate.The experimental results show that critical areas are effectively decreased by 21% on average while maintaining the routing completion rate over 99%.
Shielding Area Optimization Under the Solution of Interconnect Crosstalk
Yi-Ci Cai,Xin Zhao,Qiang Zhou,Xian-Long Hong,
Yi-Ci Cai
,Xin Zhao,Qiang Zhou,and Xian-Long Hong

计算机科学技术学报 , 2005,
Abstract: As the technology advances into deep sub-micron era, crosstalk reduction is of paramount importance for signal integrity. Simultaneous shield insertion and net ordering (SINO) has been shown to be effective to reduce both capacitive and inductive couplings. As it introduces extra shields, area minimization is also critical for an efficient SINO algorithm. In this paper, three novel algorithms using fewer shields to solve crosstalk reduction problem with RLC noise constraint are proposed, namely, net coloring (NC), efficient middle shield insertion (EMSI) and NC+EMSI two-step algorithm. Compared with the corresponding algorithms in previous work, these algorithms can reduce shielding area up to 25.77%, 46.19%, and 7.17%, respectively, with short runtime.
4,4’-Methylenebis(2-chloroaniline) (MBOCA) May Be Highly Toxic and a Carcinogen Based on an Experimental Study with Mice  [PDF]
Hong-I Chen, Tzong-Cherng Chi, Shun-Yao Ko, Yi-Chiang Hsu, I-Hsuan Lin, Ann Chen, Saou-Hsing Liou, Chien-Feng Li
Advances in Biological Chemistry (ABC) , 2014, DOI: 10.4236/abc.2014.43025
Abstract: 4,4’-Methylenebis(2-chloroaniline) (MBOCA) is a probable human carcinogen. Few studies have been performed regarding the genotoxicity of MBCOA, and the MBOCA metabolic pathway is not fully understood. We treated four-week-old ICR male mice weighing 25 - 30 g with MBOCA and observed the effects of MBOCA on the internal organs. It can be concluded that MBOCA is a carcinogen and also affects gene regulation. Oral or topical administration of 50 mg/kg, 100 mg/kg or 200 mg/kg MBOCA resulted in 56% - 81% of mice showing unusual inflammation, degeneration, and dysplasia in kidney, liver, stomach, intestine and urinary bladder based on histology. Furthermore, we investigated the association between oxidative DNA damage and MBOCA exposure by measuring plasma level of 8-hydroxydeoxyguanosine (8-OHdG). The results showed that the MBOCA-treated mice had significantly higher 8-OHdG levels than the control mice. This study confirms that MBOCA is potentially carcinogenic and highly toxic to both animals and humans.
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