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Search Results: 1 - 10 of 120356 matches for " Chunlei Wang "
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Rapid Separation of Five Cyclosporin Analogs by Supercritical Fluid Chromatography  [PDF]
Yuefei Shao, Chunlei Wang, Atsu Apedo, Oliver Mcconnell
Journal of Analytical Sciences, Methods and Instrumentation (JASMI) , 2016, DOI: 10.4236/jasmi.2016.62004
Abstract: Recently there has been a resurgence of interest in cyclic peptides due to their therapeutic advantages in terms of potency, permeability, proteolytic stability, and unique selectivity relative to traditional smaller drug molecules. Cyclosporin is a family of cyclic peptides widely used as autoimmune suppression agents. Cyclosporin analogs consist of eleven amino acids with the main difference lying at the side chain of its amino acid residues. In this study, a single step separation method was developed utilizing Supercritical Fluid Chromatography (SFC) to resolve five naturally occurring cyclosporin analogs (Cyclosporin A, B, C, D, and H) on a bare silica-packed column. The optimized method involved use of ethanol-modified carbon dioxide as mobile phase on a bare silica column at 80 °C and UV detection at 220 nm. Although column temperature and back pressure generally had insignificant effect on SFC separation, it was found in our study that increasing temperature and pressure greatly improved peak shape and resolution.
Spectral Analysis of Water Reflectance for Hyperspectral Remote Sensing of Water Quailty in Estuarine Water  [PDF]
Chunlei Fan
Journal of Geoscience and Environment Protection (GEP) , 2014, DOI: 10.4236/gep.2014.22004
Abstract: Hyperspectral remote sensing offers an effective approach for frequent, synoptic water quality measurements over a large spatial extent. However, the optical complexity of case 2 water makes the water quality monitoring by remote sensing in estuarine water a challenge. The prime objective of this study was to develop algorithms for hyperspectral remote sensing of water quality based on in situ spectral measurement of water reflectance. In this study, water reflectance spectra R(λ) were acquired by a pair of Ocean Optic 2000 spectroradiometers during the summers from 2008 to 2011 at Patuxent River, a tributary of Chesapeake Bay, USA. Simultaneously, concentrations of chlorophyll a and total suspended solids (TSS), as well as absorption of colored dissolved organic matter (CDOM) were measured. Empirical models that based on spectral features of water reflectance generally showed good correlations with water quality parameters. The retrieval model that using spectral bands at red/NIR showed a high correlation with chlorophyll a concentration (R2 = 0.81). The ratio of green to blue spectral bands is the best predictor for TSS (R2 = 0.75), and CDOM absorption is best correlated with spectral features at blue and NIR regions (R2 = 0.85). These empirical models were further applied to the ASIA Eagle hyperspectral aerial imagery to demonstrate the feasibility of hyperspectral remote sensing of water quality in the optical complex estuarine waters.
A Compressible High-Order Unstructured Spectral Difference Code for Stratified Convection in Rotating Spherical Shells
Junfeng Wang,Chunlei Liang,Mark S. Miesch
Physics , 2015, DOI: 10.1016/j.jcp.2015.02.047
Abstract: We present a novel and powerful Compressible High-ORder Unstructured Spectral-difference (CHORUS) code for simulating thermal convection and related fluid dynamics in the interiors of stars and planets. The computational geometries are treated as rotating spherical shells filled with stratified gas. The hydrodynamic equations are discretized by a robust and efficient high-order Spectral Difference Method (SDM) on unstructured meshes. The computational stencil of the spectral difference method is compact and advantageous for parallel processing. CHORUS demonstrates excellent parallel performance for all test cases reported in this paper, scaling up to 12,000 cores on the Yellowstone High-Performance Computing cluster at NCAR. The code is verified by defining two benchmark cases for global convection in Jupiter and the Sun. CHORUS results are compared with results from the ASH code and good agreement is found. The CHORUS code creates new opportunities for simulating such varied phenomena as multi-scale solar convection, core convection, and convection in rapidly-rotating, oblate stars.
Low-Thermal-Conductivity (MS)1+x(TiS2)2 (M = Pb, Bi, Sn) Misfit Layer Compounds for Bulk Thermoelectric Materials
Chunlei Wan,Yifeng Wang,Ning Wang,Kunihito Koumoto
Materials , 2010, DOI: 10.3390/ma3042606
Abstract: A series of ( MS) 1+x(TiS 2) 2 ( M = Pb, Bi, Sn) misfit layer compounds are proposed as bulk thermoelectric materials. They are composed of alternating rock-salt-type MS layers and paired trigonal anti-prismatic TiS 2 layers with a van der Waals gap. This naturally modulated structure shows low lattice thermal conductivity close to or even lower than the predicted minimum thermal conductivity. Measurement of sound velocities shows that the ultra-low thermal conductivity partially originates from the softening of the transverse modes of lattice wave due to weak interlayer bonding. Combined with a high power factor, the misfit layer compounds show a relatively high ZT value of 0.28~0.37 at 700 K.
A General Framework for Network Survivability Testing and Evaluation
Chunlei Wang,Liang Ming,Jinjing Zhao,Dongxia Wang
Journal of Networks , 2011, DOI: 10.4304/jnw.6.6.831-841
Abstract: The survivability of network is of vital importance with respect to the normal operation of information infrastructure. The current research works in the area of network survivability generally aimed at the definitions and quantifications of specific survivability attributes or metrics for distinct network objects. Unfortunately, there is a lack of research concerning how to model, test and evaluate the survivability of network in a consistent manner, and it is helpful to the unification of network survivability testing and evaluation and the promotion of related research works in the area of network survivability. Furthermore, the requirements for network survivability testing and evaluation are variable among different application domains. Therefore, a flexible mechanism to support the customizable
Study on the Qiang’s Costume Culture—A Case Study of the Qiang’s Costumes in Li County  [PDF]
Chunlei Song, Bing Zhao
Open Journal of Social Sciences (JSS) , 2018, DOI: 10.4236/jss.2018.66020
Abstract: As a part of fifty-six ethnic minorities, the Qiang ethnic has long-established national culture and is also an important part of intangible cultural heritage. The article outlines the connotation of the Qiang’s culture, elaborates the aesthetic characteristics, pattern characteristics, color characteristics, and compositional characteristics of the Qiang’s costumes. Taking the Qiang’s costumes in the Mao County area as an example, through analysing the materials of Qiang’s costumes in the Mao County, the paper deeply analyzes the differences in cultural customs and dressing habits between different regions. The unique geographical features of Li County’s clothing are summarized based on these differences. The Qiang ethnic calls itself “er ma” or “er mie”, and it is also being called “nation on the cloud”. They are mainly distributed in Maoxian, Wenchuan, Lixian, Songpan and Heishui counties in Aba Tibetan and Qiang Autonomous Prefecture of Sichuan Province and Beichuan Qiang Autonomous County in Mianyang City. The rest are scattered in Danba County in Ganzi Tibetan Autonomous Prefecture of Sichuan Province, Pingwu County in Mianyang City and Jiangkou County and Shiji County in Tongren Prefecture of Guizhou Province. This article focuses on Qiang costume culture in Li County of Aba Tibetan and Qiang Autonomous Prefecture in Sichuan Province.
The Relationship between Oral Squamous Cell Carcinoma and Human Papillomavirus: A Meta-Analysis of a Chinese Population (1994–2011)
Changtai Zhu, Yang Ling, Chunlei Dong, Xifa Zhou, Feng Wang
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0036294
Abstract: Background Previous studies indicated that oral squamous cell carcinomas (OSCC) might be related to human papilloma virus (HPV) infection. However, up to now, there still lacks a large sample study to analyze the relationship between OSCC in a Chinese population and oral HPV infection. In the present study, we used a meta-analysis to evaluate the relationship of OSCC with HPV infection in a Chinese population. Methods The reports on HPV and OSCC in a Chinese population published between January, 1994, and September, 2011 were retrieved via CNKI/WANFANG/OVID/MEDLINE databases. According to the inclusion criteria, we selected 18 eligible case-control studies. After testing the heterogeneity of the studies by the Cochran Q test, the meta-analyses for HPV and HPV16 were performed using the fixed effects model. Results The overall positive rates of HPV and HPV16 in OSCC were 58.0% (354/610; 95% confidence interval [CI], 54.1–61.9) and 47.47% (169/356; 95% CI: 42.3–52.7), respectively; which were significantly higher than those in normal controls 10.44% (26/249; 95% CI: 7.2–14.7) and 7.1% (13/182; 95% CI: 4.2–11.8). Quantitative meta-analysis revealed that, compared with normal controls, the combined odds ratios of OSCC with HPV or HPV16 infection were 12.7 (95% CI: 8.0–20.0) and 9.0 (95% CI: 5.1–15.6), respectively. Both Begg's test and funnel plots revealed that no publication bias was found in this present study (P>0.05). Conclusions High incidences of HPV infection (mainly involving HPV16) were found in the samples of Chinese OSCC. For the Chinese population, HPV infection elevates the risk of OSCC tumorigenesis. Prophylactic HPV-vaccination may reduce the burden of HPV-related OSCC in China.
Preparation of CdTe nanocrystal-polymer composite microspheres in aqueous solution by dispersing method
Minjie Li,Chunlei Wang,Kun Han,Bai Yang
Chinese Science Bulletin , 2005, DOI: 10.1360/04wb0127
Abstract: Highly fluorescent CdTe nanocrystals were synthesized in aqueous solution, and then processible CdTe nanocrystal-polymer composites were fabricated by coating the aqueous nanocrystals with copolymers of styrene and octadecyl-p-vinyl-benzyldimethylammonium chloride (SOV-DAC) directly. A dichloromethane solution of CdTe nanocrystal-polymer composites was dispersed in the aqueous solution o0f poly (vinyl alcohol) (PVA) generating highly fluorescent microspheres. Experimental parameters such as the concentration of nanocrystal-polymer composites, the concentration of PVA, and stirring speed which had important effect on the preparation of the microspheres were investigated in detail with fluorescent microscope characterization.
First-principle study on the physical properties of ultra-incompressible ReB2

Chunlei WANG,Qiuju SUN,Xuanyu SONG,Benhai YU,

金属学报(英文版) , 2009,
Abstract: The elastic and physical characteristics of ReB2 crystal have been predicted through a method of density functional theory within the generalized gradient approximation (GGA). Five independent elastic constants are C11=662 GPa, C12=150 GPa, C13=146 GPa, C33=1090 GPa and C44=263 GPa. The bulk modulus (B), shear modulus (G), Young's modulus (E), Poisson's ratio (γ) and the ratio of linear compressibility coefficient along the a- and c-axis crystal direction (Ka/Kc) are 356 GPa, 305 GPa, 711 GPa, 0.167 and 1.758, respectively. In addition, the dependence of bulk modulus (B) on temperature (T) and pressure (p) as well as the coefficient of thermal expansion (αL) at various temperatures are evaluated and discussed. The coefficient of thermal expansion is consistent with the famous Gruneisen's law when the temperature is less than 1500K. Our results agree well with the other experimental results.
Ling Wang,Ziqian Chang,Chunlei Ding,Hua Shao
Acta Crystallographica Section E , 2011, DOI: 10.1107/s1600536811013687
Abstract: In the title compound, C16H21BrO2, the cyclohexane ring is in a chair conformation and its least-squares plane is at an angle of 61.3 (9)° to the benzene ring. The crystal packing is stabilized by weak π–π stacking interactions [centroid–centroid distance = 3.697 (9) ] between the bromomethoxyphenyl rings of neighbouring molecules.
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