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Search Results: 1 - 10 of 48765 matches for " Chun-Pyo Hong "
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Ulmus davidiana var. japonica Nakai Upregulates Eosinophils and Suppresses Th1 and Th17 Cells in the Small Intestine
Han-Sung Lee, Min Seong Jang, Jung-Hwan Kim, Chun-Pyo Hong, Eun-Jung Lee, Eun Ji Jeun, Chan Kim, Eun-Kyung Kim, Kwang-Seong Ahn, Bo-Gie Yang, Kwang Seok Ahn, Young Pyo Jang, Kyoo-Seok Ahn, You-Me Kim, Myoung Ho Jang
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0076716
Abstract: The bark of Ulmus davidiana var. japonica Nakai (Ulmaceae) has been used in traditional Korean medicine for chronic inflammation in the gastrointestinal tract. Here we investigated the frequency and cytokine profile of the major immune cells in the small intestinal lamina propria (SI LP), spleen, and mesenteric lymph nodes (MLNs) of mice treated orally with Ulmus davidiana var. japonica Nakai bark water extract (UDE) to address the immunomodulatory role of this herb in intestinal homeostasis. B6 mice were given 5g/kg UDE once daily for 14 days. They were then sacrificed, and cells were isolated from the spleen, MLNs, and SI LP. The proportion of B versus T lymphocytes, CD4+ versus CD8+ T lymphocytes, Th1 and Th17 cells, and Foxp3+ regulatory T cells in the spleen, MLNs, and SI LP were analyzed. The frequency of antigen-presenting cells (APCs), including dendritic cells, macrophages, and eosinophils in the SI LP and the expression of costimulatory molecules on APCs were also evaluated. The numbers and frequencies of Th1 and Th17 cells in the SI LP were significantly reduced in the UDE-treated mice compared with PBS controls. In addition, the proportion of IL-4-producing eosinophils in the SI LP was significantly elevated in the UDE-treated mice compared with controls. Taken together, these data indicate that UDE up-regulates the number and frequency of SI LP eosinophils, which can down-regulate the Th1 and Th17 responses via IL-4 secretion and contribute to intestinal homeostasis.
Clinical significance of clusterin expression in pancreatic adenocarcinoma
Junshuo Jin, Joon-Mee Kim, Yoon-Seok Hur, Won Pyo Cho, Keon-Young Lee, Seung-Ik Ahn, Kee Chun Hong, In-Sun Park
World Journal of Surgical Oncology , 2012, DOI: 10.1186/1477-7819-10-146
Abstract: Immunohistochemical staining was performed for clusterin in tumor tissues obtained from patients who received pancreatic resection with radical intent, and the associations of clusterin expression with various clinicopathologic parameters were analyzed in addition to the relation between its expression and survival.Immunoreactivity for clusterin was observed in 17 of the 52 (33%) pancreatic adenocarcinomas examined. In addition, clusterin positivity was found to be associated with preoperative serum carcinoembryonic antigen level, perineural invasion, and, most strongly, lymph node metastasis. The survival analysis identified tumor differentiation and lymph node metastasis as the only significant prognostic factors.Although not an independent prognostic factor, clusterin immunoreactivity can be used in conjunction with lymph node metastasis to predict survival in cases of pancreatic adenocarcinoma.
Characterization of Corydalis (Papaveraceae s. l.) and Dioscorea (Dioscoreaceae) Species: 1. Root Anatomical Characters
Sophia Wan-Pyo Hong
International Journal of Biology , 2012, DOI: 10.5539/ijb.v4n3p1
Abstract: Resin embedding methodology was evaluated for authentic herbal medicinal identification using tubers or rhizomes of Corydalis and Dioscorea in the current study. Dealing with hard herbal drug materials for anatomical works can be challenging, but using the resin embedding approach makes easier to dissect the herbal drugs. Corydalis and Dioscorea tubers are secondary organs considering the fact that they have main roots as well as the tubers or rhizomes. The tuber anatomical characters are not complicated; however, the characteristic anatomical features can be useful as identification tools for those well-known Oriental herbal medicines.
Random Local Clock and Molecular Evolution Studies on Corydalis (Papaveraceae s. l.)
Sophia Wan-Pyo Hong
International Journal of Biology , 2012, DOI: 10.5539/ijb.v4n4p31
Abstract: Molecular evolutionary rate and dating studies have been carried out on nuclear ribosomal DNA (nrDNA ITS I and II) and non-coding plastid DNA (rps16 intron) nucleotide sequences from Corydalis and other related genera in the poppy family Papaveraceae s. l. Strict, relaxed, and local clock models have been compared. Although it has been suggested that the nrDNA ITS I and II regions evolved in concert, they may have evolved at different evolutionary rates under differential constraints. Based on random local clock and uncorrelated relaxed lognormal clock Bayesian analyses using BEAST v.1.6.2, the ITS II region may have evolved in a clock-like fashion.
Root Anatomical Characters of Herbal Drug Sophora (Fabaceae) Using Resin Embedding
Sophia Wan-Pyo Hong
International Journal of Biology , 2012, DOI: 10.5539/ijb.v4n3p56
Abstract: Sophora root has been used for many years in traditional herbal medicine both as a pain reliever and also as a treatment for cancer and thus there is a need for rapid and accurate identification of individual species. Other workers have shown that stem xylem characteristics of Sophora are informative at intraspecific levels. As stem and root woods share similar properties, we report studies based on anatomical characteristics of root specimens from Sophora to develop an identification tool for individual Sophora species. Light microscopy was employed. A resin embedding approach was chosen instead of wax embedding because herbal drug materials are very dry and difficult to section thinly. It is shown that root xylem characteristics of Sophora may be used for identification. Root anatomical characters of Sophora can be used for herbal drug identification at intra- (e.g. species) and infra (e.g. varieties)-specific levels. Quantitative data will be gathered in further studies.
Algorithm as Defining Dynamic Systems
Keehang Kwon,Hong Pyo Ha
International Journal of Computer Science and Information Security , 2009,
Abstract: This paper proposes a new view to algorithms: Algorithms as defining dynamic systems. This view extends the traditional, deterministic view that an algorithm is a step-by-step procedure with nondeterminism. As a dynamic system can be designed by a set of its defining laws, it is also desirable to design an algorithm by a (possibly nondeterministic) set of defining laws. This observation requires some changes to algorithm development. We propose a two-step approach: the first step is to design an algorithm via a set of defining laws of dynamic system. The second step is to translate these laws (written in a natural language) into a formal language such as linear logic.
Algorithm as Defining Dynamic Systems
Keehang Kwon,Hong Pyo Ha
Computer Science , 2009,
Abstract: This paper proposes a new view to algorithms, Algorithms as defining dynamic systems. This view extends the traditional, deterministic view that an algorithm is a step by step procedure with nondeterminism. As a dynamic system can be designed by a set of its defining laws, it is also desirable to design an algorithm by a (possibly nondeterministic) set of defining laws. This observation requires some changes to algorithm development. We propose a two step approach, the first step is to design an algorithm via a set of defining laws of dynamic system. The second step is to translate these laws (written in a natural language) into a formal language such as linear logic.
Single port laparoscopic hysterectomy: Feasibility and safety  [PDF]
Soon Pyo Lee, Sun Hye Yang, Chun Hoe Ku, Sung Ho Lee, Jin Woo Shin
Open Journal of Obstetrics and Gynecology (OJOG) , 2013, DOI: 10.4236/ojog.2013.37A2001
Abstract:

Objective: To evaluate the feasibility and safety of single-port laparoscopic hysterectomy comparing with multi-port laparoscopic hysterectomy in treatment of benign uterine diseases. Methods: Data were collected retrospectively by review of the medical records of 252 patients who underwent multi-port or single-port laparoscopic surgery for treatment of benign gynecologic diseases. Laparoscopy assisted vaginal hysterectomy (LAVH) was performed for single-port surgery and LAVH and total laparoscopic hysterectomy (TLH) were performed for multi-port surgery. Demographic variables were collected and analyzed by independent t-test and Pearson Chi-Square test. The primary outcome was analyzed by independent t-test and Fisher’s Exact test. Results: A longer operative time was observed in the multi-port surgery group compared with that of the single-port group (p < 0.05). No difference with respect to change of Hemoglobin between the preoperative level and that of the postoperative first day, the number of days from the operation to discharge, uterine weight, and the rate of laparotomy conversion and complications were observed between the two groups. Conclusion: Single-port laparoscopic hysterectomy for treatment of benign uterine diseases is a safe and feasible method.

Investigation on Propagation Characteristics of Super-Gaussian Beam in Highly Nonlocal Medium
Manoj Mishra;Woo-Pyo Hong
PIER B , 2011, DOI: 10.2528/PIERB11051302
Abstract: We investigate the propagation characteristics of super-Gaussian beam in highly nonlocal nonlinear media. The optical beam propagation has been modeled by well known nonlocal nonlinear Schr dinger equation. The variational method is employed to find the initial beam propagation parameters and then split step Fourier method is used for numerical simulations. A generalized exact analytical solution of the model is obtained and critical power of soliton is determined. The evolution of super-Gaussian beam has shown oscillatory propagation.
Does high-stakes testing increase cultural capital among low-income and racial minority students?
Won-Pyo Hong,Peter Youngs
Education Policy Analysis Archives , 2008,
Abstract: This article draws on research from Texas and Chicago to examine whether high-stakes testing enables low-income and racial minority students to acquire cultural capital. While students' performance on state or district tests rose after the implementation of high-stakes testing and accountability policies in Texas and Chicago in the 1990s, several studies indicate that these policies seemed to have had deleterious effects on curriculum, instruction, the percentage of students excluded from the tests, and student dropout rates. As a result, the policies seemed to have had mixed effects on students' opportunities to acquire embodied and institutionalized cultural capital. These findings are consistent with the work of Shepard (2000), Darling-Hammond (2004a), and others who have written of the likely negative repercussions of high-stakes testing and accountability policies.
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