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Search Results: 1 - 10 of 12093 matches for " Chris Nadège Nganou-Gnindjio "
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Blood Pressure Response to Cold Stress in Black Cameroonian Adults  [PDF]
Sylvie Ndongo Amougou, Hamadou Ba, Chris Nadège Nganou-Gnindjio, Dieudonné Danwe, Jingi Musa Ahmadou, Liliane Kuate Mfeukeu, Jérome Hilaire Boomhbi, Christian Ngongang Ouankou, Samuel Kingue
Open Access Library Journal (OALib Journal) , 2017, DOI: 10.4236/oalib.1104111
Introduction: The cold test is known as a predictor of essential hypertension. The hemodynamic response to this test has rarely been studied in black African adults. Black Africans also suffer cold stress. But whether they suffer it the same way as other populations is still to be determined. Equipment and Method: We studied the response of blood pressure (BP) during the cold test in 62 black normotensive adults and hypertensive Cameroonians aged between 21 and 59 years. Those with an increase in systolic blood pressure (SBP) > 20 mmHg and/or diastolic blood pressure > 15 mmHg were considered to be hyper-reactors. Results: SBP increased significantly in hyper-reactors compared with normo-reactors in both hypertensive and normotensive subjects (176 ± 20 vs. 154 ± 11, p = 0.01 and 148 ± 17 vs. 125 ± 11, p < 0.001, respectively) and this increment persisted up to two minutes after the end of the stress exposure although the difference was no more statistically significant. We found the same result for the DBP (111 ± 13 vs. 99 ± 10, p = 0.04 and 95 ± 11 vs. 81 ± 10, p = 0.001, respectively). However, the DBP stayed higher in hyper reactors compared to normal reactors in the normotensive group up to four minutes after cessation of the stress exposure. The recovery time of the baseline BP was considerably longer in hyper reactors compared with the normal reactors (2.1 ± 0.9 vs. 1.1 ± 0.4 minutes, p = 0.01 and 1.9 ± 1.0 vs. 1.3 ± 0.5 minutes, p = 0.03 respectively in hypertensive and normotensive). Conclusion: Hyper reactors in the cold test have a more pronounced and prolonged reactivity. They are thus predisposed to develop hypertension.
Effect of Therapeutic Group Education on Adherence and Blood Pressure Control among Uncontrolled Hypertensive Patients in Sub Saharan Africa  [PDF]
Chris Nadège Nganou-Gnindjio, Hélo?se Guidelle Kenmogne Domning, Liliane Mfeukeu-Kuate, Ba Hamadou, Félicité Kamdem, Georges Bediang, Aurel T. Tankeu, Alain Patrick Menanga, Samuel Kingue
World Journal of Cardiovascular Diseases (WJCD) , 2018, DOI: 10.4236/wjcd.2018.83018
Abstract: Background: Hypertension is the leading cardiovascular risk factor worldwide, with the greatest burden in low-income settings. Blood pressure (BP) control is usually low resulting in high rates of uncontrolled patients and complications. Low awareness resulting in poor therapeutic adherence represents an important factor for insufficient blood pressure control in developing countries. Methods: This was a three months non-randomized control trial at the cardiology clinic of the Yaoundé Central Hospital. We included adults with essential and uncontrolled hypertension. The intervention consisted of group educative sessions every week focusing on knowledge of hypertension risk factors, complications, treatment, comorbidities, home self-monitoring of BP. Home blood pressure figures, drug compliance, and knowledge regarding hypertension were evaluated before and after. Results: 17 participants (8 women) with a mean age 56.2 ± 8.1 years. During intervention, mean SBP decreased by 30 mmHg while mean DBP drooped by 11 mmHg using home BP measures. Knowledge regarding hypertension, adherence and drug compliance increased by 36.5%, 88.2% and 81.4% respectively. Conclusion: Therapeutic group education resulted in a significant improvement in BP control amongst uncontrolled hypertensive patients in sub Saharan Africa.
Prevalence, Awareness, and Control of Hypertension in Health Workers of Two Teaching Hospitals of Yaounde-Cameroon: The Hypertension Awareness Initiative (THAI) Pilot Survey  [PDF]
Sylvie Ndongo Amougou, Karen Kamgoum Tchokote, Ba Hamadou, Ahmadou Musa Jingi, Chris Nadège Nganou-Gnindjio, Marie Ntep Ngwet, Liliane Mfeukeu Kuaté, Bonaventure Jemea, Lucie Ebah Epok, Dieudonné Danwé, Samuel Kingue
Open Access Library Journal (OALib Journal) , 2018, DOI: 10.4236/oalib.1104820
Introduction: High blood pressure is a public problem worldwide because of its high morbidity and mortality. The greatest burden is in low-income set-tings. The burden of disease has not been studied in health workers in our setting. Methods: Between December 2016 and June 2017, we carried out a cross-sectional descriptive and analytic study in two teaching hospitals in Yaounde, using the WHO STEP wise approach. Participants were consenting Physicians, Nurses, Midwives, and Nursing assistants of both sex, aged ≥ 21 years. Results: A total of 266 health workers were screened—31 Physicians, 144 Nurses, 80 Nursing assistants, and 11 Midwives. Their mean age was 41.1 ± 7.6 years (25 to 66 years), and 84.6% were females. The prevalence of Hypertension was 13.9%, of which 54.1% were newly diagnosed—Awareness rate of 45.9%. The control rate of known cases of hy-pertension was 64.7% (64.3% in those on monotherapy, and 66.7% in those on bitherapy). Age > 40 years, and adiposity were significantly associated with hypertension. Conclusion: Compared to the general population, the prevalence of hypertension amongst health workers was low, but with a high rate of un-awareness.
Epidemiologic Aspects of Atrial Fibrillation in a Tertiary Hospital in a Sub-Saharan Africa Setting  [PDF]
Félicité Kamdem, Ba Hamadou, Marius Kamdem, Christ Nadège Nganou, Anastase Dzudie, Yves Monkam, Samuel Kingue
Open Access Library Journal (OALib Journal) , 2017, DOI: 10.4236/oalib.1103384
Background: Atrial fibrillation (AF) is the most frequent sustained arrhythmia. The prevalence is increasing with that of other cardiovascular risk factors in our low-income setting. It is potentially serious due to the associated complications. Few data exist on the epidemiology of AF in Sub-Saharan Africa (SSA). Methodology: We carried out a cross-sectional study between 2005 and 2009 in the Cardiology Unit of the Douala General Hospital. Patients were adults ≥ 18 years of both sex, who had an ECG diagnosis of Atrial Fibrillation and a comprehensive investigation of the cause of AF. Results: A total of 2581 patients were seen in this unit, of whom 182 (7.1%, [95%: 6.1-8.1]) had AF. Their mean age was 59.2 ± 15.4 years, and there were 100 (58.2%, [95% CI: 51-65.6], p = 0.002) females. Hypertension was the most frequent risk factor (77.3%, [95% CI: 70.3-82.8]), and 163 (95.3%, [95% CI: 90.7-97.8]) of the patients were symptomatic. Hypertensive heart disease (45.6%, [95% CI: 38.3-53.1]), idiopathic dilated cardiomyopathy (19.3%, [95% CI: 14.1-25.9]), and valvular heart disease (16.4%, [95% CI: 11.6-22.6]) were the main etiologic factors of AF. The most frequent complications were heart failure seen in 77 (45%, [37.8-52.5]) and ischemic stroke in 27 (15.5%, [95% CI: 11.1 - 22]) of patients. Digoxine was prescribed in 121 (70.8%, [95% CI: 63.6-77.1]) patients to control heart rate, while amiodarone was prescribed in 67 (29.2%, [95% CI: 32.2-46.7]) patients to revert to sinus rhythm. No electrical cardioversion was carried out. Aspirine was prescribed in 119 (69.6%, [95% CI: 62.3-76]) patients, and anti-vitamin K in 53 (30.4%, [95% CI: 24.5-38.3]) patients. Conclusion: Atrial fibrillation was seen in seven percent of patients in the Cardiology Unit of this low-income setting. Patients were relatively young compared with high income settings. Hypertension, idiopathic dilated cardiomyopathy, and valvular heart disease were the main causes. Rate control was the main treatment strategy. Oral anti-coagulants were less frequently used.

Serological Studies of Neurologic Helminthic Infections in Rural Areas of Southwest Cameroon: Toxocariasis, Cysticercosis and Paragonimiasis
Agathe Nkouawa,Yasuhito Sako,Sonoyo Itoh,Alida Kouojip-Mabou,Christ Nadège Nganou,Yasuaki Saijo,Jenny Knapp,Hiroshi Yamasaki,Minoru Nakao,Kazuhiro Nakaya,Roger Moyou-Somo,Akira Ito
PLOS Neglected Tropical Diseases , 2010, DOI: 10.1371/journal.pntd.0000732
Abstract: Background Both epilepsy and paragonimiasis had been known to be endemic in Southwest Cameroon. A total of 188 people (168 and 20 with and without symptoms confirmed by clinicians, respectively, 84.6% under 20 years old) were selected on a voluntary basis. Among 14 people (8.3%) with history of epilepsy, only one suffered from paragonimiasis. Therefore, we challenged to check antibody responses to highly specific diagnostic recombinant antigens for two other helminthic diseases, cysticercosis and toxocariasis, expected to be involved in neurological diseases. Soil-transmitted helminthic infections were also examined. Methodology/Principal Findings Fecal samples were collected exclusively from the 168 people. Eggs of Ascaris lumbricoides, Trichuris trichiura and hookworms were found from 56 (33.3%), 72 (42.8%), and 19 (11.3%) persons, respectively. Serology revealed that 61 (36.3%), 25 (14.9%) and 2 (1.2%) of 168 persons showed specific antibody responses to toxocariasis, paragonimiasis and cysticercosis, respectively. By contrast, 20 people without any symptoms as well as additional 20 people from Japan showed no antibody responses. Among the 14 persons with epilepsy, 5 persons were seropositive to the antigen specific to Toxocara, and one of them was simultaneously positive to the antigens of Paragonimus. The fact that 2 children with no history of epilepsy were serologically confirmed to have cysticercosis strongly suggests that serological survey for cysticercosis in children is expected to be useful for early detection of asymptomatic cysticercosis in endemic areas. Conclusions/Significance Among persons surveyed, toxocariasis was more common than paragonimiasis, but cysticercosis was very rare. However, the fact that 2 children were serologically confirmed to have cysticercosis was very important, since it strongly suggests that serology for cysticercosis is useful and feasible for detection of asymptomatic cysticercotic children in endemic areas for the early treatment.
Le Crépuscule de la chevalerie : le cycle arthurien de Rutland Boughton (1878-1960) et l’épopée nationale ”The Twilight of the Knights”: Rutland Boughton’s Arthurian cycle and national epic
Nadège Le?Lan
Revue LISA / LISA e-journal , 2009, DOI: 10.4000/lisa.1136
Abstract: “A man holding in one hand a crown of laurel, in the other a crown of thorn”. This is the closing vision of the first part of Rutland Boughton’s Arthurian cycle, composed between 1908 and 1945 (The Round Table, 1915; The Birth of Arthur, 1920; The Lily Maid, 1934; Galahad and Avalon, never produced). The work advocates communal principles with a Christian spirit and the union of human beings with nature. It intends to imitate Wagner’s Ring and faces the double goal of being national and modern. The study focuses on the libretto, through both the adaptation of the national myth and the reference to Wagner.
L’étude de la rencontre touristique en terrains africains.
Nadège Chabloz
EspacesTemps.net , 2010,
Abstract: Cette contribution décrit et analyse les différentes situations de restitutions d’enquêtes menées sur la rencontre touristique au Burkina Faso et au Gabon. Si j’ai effectué les restitutions de mes enquêtes — sous formes écrite, filmique ou de débat — dans une démarche de contre-don envers mes interlocuteurs, qui s’étaient donné la peine de jouer le jeu de l’enquête ethnographique, et qu’elle a été re ue comme telle par un certain nombre d’entre eux, il est également arrivé que des restitutions soient per ues par d’autres comme des points de vue exogènes ou comme de véritables agressions.
Interdependent Utilities: How Social Ranking Affects Choice Behavior
Nadège Bault, Giorgio Coricelli, Aldo Rustichini
PLOS ONE , 2008, DOI: 10.1371/journal.pone.0003477
Abstract: Organization in hierarchical dominance structures is prevalent in animal societies, so a strong preference for higher positions in social ranking is likely to be an important motivation of human social and economic behavior. This preference is also likely to influence the way in which we evaluate our outcome and the outcome of others, and finally the way we choose. In our experiment participants choose among lotteries with different levels of risk, and can observe the choice that others have made. Results show that the relative weight of gains and losses is the opposite in the private and social domain. For private outcomes, experience and anticipation of losses loom larger than gains, whereas in the social domain, gains loom larger than losses, as indexed by subjective emotional evaluations and physiological responses. We propose a theoretical model (interdependent utilities), predicting the implication of this effect for choice behavior. The relatively larger weight assigned to social gains strongly affects choices, inducing complementary behavior: faced with a weaker competitor, participants adopt a more risky and dominant behavior.
Maternal Diet Influences Offspring Feeding Behavior and Fearfulness in the Precocial Chicken
Nadège Aigueperse, Ludovic Calandreau, Aline Bertin
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0077583
Abstract: Background In chicken, oils in the maternal diet confer a specific scent to the yolk. Embryos are known to perceive and memorize chemosensory signals of the surrounding environment; however, the potential impact of the maternal diet has not previously been investigated. In the present study, we hypothesized that chicken embryos memorize the chemical signals of the maternal diet and that this perceptual learning may orient subsequent feeding behavior of the hatchlings. Methodology/Principal Findings Laying hens were fed standard food enriched with 2% menhaden oil (MH group) or 2% soybean oil (controls). The scent of menhaden was significantly more detected in MH egg yolks than in control yolks by a human panel. We analyzed the development and behavior of offspring towards different types of food, bearing or not bearing the menhaden scent. When chicks were exposed to a 3-min choice test between the familiar food bearing the menhaden scent and the familiar food without menhaden, no effect of treatment was observed. In a 3-min choice test with unfamiliar food (mashed cereals) MH chicks showed a clear positive orientation toward the unfamiliar food bearing the menhaden scent. By contrast, control chicks showed a preference for the non-odorized unfamiliar food. MH chicks expressed higher emotional reactivity level than control chicks as expressed by food neophobia and longer immobility in a restraint test. Conclusion/Significance Chicks exposed in ovo to menhaden oil via the maternal diet preferentially oriented their feeding behavior towards food containing menhaden oil, but only when the food was unfamiliar. We propose that oil in the maternal diet engenders maternal effects and contributes to the development of behavioral phenotype in the offspring. In ovo chemosensory learning may have evolved to prepare precocial offspring for their environment. This suggests a common principle of embryonic chemosensory learning across vertebrate taxa.
High resolution nuclear magnetic resonance investigation of metabolic disturbances induced by focal traumatic brain injury in a rat model: a pilot study  [PDF]
Laurent Lemaire, Fran?ois Seguin, Florence Franconi, Delphine Bon, Anne Pasco, Nadège Boildieu, Jean-Jacques Le Jeune
Journal of Biomedical Science and Engineering (JBiSE) , 2011, DOI: 10.4236/jbise.2011.42016
Abstract: Experimental models of traumatic brain injury (TBI) provide a useful tool for understanding the cerebral metabolic changes induced by this pathological condition. Here, we report on the time course of changes in cerebral metabolites after TBI using high-resolution proton magnetic resonance spectroscopy (NMR). Extracts from adult male Sprague-Dawley rats were subjected to fluid lateral percussion and were then examined by NMR at 3, 24 and 48 h after the injury. A metabolomic approach was carried out to identify the cerebral metabolites impacted by the TBI and their quantitative temporal changes. Lactate, valine and ascorbate were the three first metabolites to be significantly modified after TBI. The quantitative elevation for these compounds last for the entire experimental time explored. Within 24 hours post-TBI, a significant elevation in choline-derivates, alanine and glucose were also measured. On the other hand, N-acetyl aspartate, a neuronal marker, and myo- inositol, an important organic osmolyte in the mammalian brain, were not significantly impacted in the chronic phase of TBI.
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