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Search Results: 1 - 10 of 55418 matches for " Chien-Liang Huang "
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Template Matching using Statistical Model and Parametric Template for Multi-Template  [PDF]
Chin-Sheng Chen, Jian-Jhe Huang, Chien-Liang Huang
Journal of Signal and Information Processing (JSIP) , 2013, DOI: 10.4236/jsip.2013.43B009

This paper represents a template matching using statistical model and parametric template for multi-template. This algorithm consists of two phases: training and matching phases. In the training phase, the statistical model created by principal component analysis method (PCA) can be used to synthesize multi-template. The advantage of PCA is to reduce the variances of multi-template. In the matching phase, the normalized cross correlation (NCC) is employed to find the candidates in inspection images. The relationship between image block and multi-template is built to use parametric template method. Results show that the proposed method is more efficient than the conventional template matching and parametric template. Furthermore, the proposed method is more robust than conventional template method.

Corner-Based Image Alignment using Pyramid Structure with Gradient Vector Similarity  [PDF]
Chin-Sheng Chen, Kang-Yi Peng, Chien-Liang Huang, Chun-Wei Yeh
Journal of Signal and Information Processing (JSIP) , 2013, DOI: 10.4236/jsip.2013.43B020

This paper presents a corner-based image alignment algorithm based on the procedures of corner-based template matching and geometric parameter estimation. This algorithm consists of two stages: 1) training phase, and 2) matching phase. In the training phase, a corner detection algorithm is used to extract the corners. These corners are then used to build the pyramid images. In the matching phase, the corners are obtained using the same corner detection algorithm. The similarity measure is then determined by the differences of gradient vector between the corners obtained in the template image and the inspection image, respectively. A parabolic function is further applied to evaluate the geometric relationship between the template and the inspection images. Results show that the corner-based template matching outperforms the original edge-based template matching in efficiency, and both of them are robust against non-liner light changes. The accuracy and precision of the corner-based image alignment are competitive to that of edge-based image alignment under the same environment. In practice, the proposed algorithm demonstrates its precision, efficiency and robustness in image alignment for real world applications.

Computer Tomography and Ultrasonography Image Registration Based on the Cooperation of GPU and CPU  [PDF]
Ying-Chih Lin, Chien-Liang Huang, Chin-Sheng Chen, Wen-Chung Chang, Yu-Jen Chen, Chia-Yuan Liu
Journal of Signal and Information Processing (JSIP) , 2013, DOI: 10.4236/jsip.2013.43B014

Image registration is wildly used in the biomedical image, but there are too many textures and noises in the biomedical image to get a precise image registration. In order to get the excellent registration performance, it needs more complex image processing, and it will spend expensive computation cost. For the real time issue, this paper proposes edge gradient direction image registration applied to Computer Tomography(CT) image and Ultrasonography (US) image based on the cooperation of Graphic Processor Unit (GPU) and Central Processor Unit (CPU). GPU can significantly reduce the computation time. First, the CT image slice is extracted from the CT volume by the region growing and the interpolation algorithm. Secondly, the image pre-processing is employed to reduce the image noises and enhance the image features. There are two kinds of the image pre-processing algorithms invoked in this paper: 1) median filtering and 2) anisotropic diffusion. Last but not least, the image edge gradient information is obtained by Canny operator, and the similarity measurement based on gradient direction is employed to evaluate the similarity between the CT and the US images. The experimental results show that the proposed architecture can distinctively improve the efficiency and are more suitably applied to the real world.

Local Anesthetics Induce Apoptosis in Human Thyroid Cancer Cells through the Mitogen-Activated Protein Kinase Pathway
Yuan-Ching Chang, Yi-Chiung Hsu, Chien-Liang Liu, Shih-Yuan Huang, Meng-Chun Hu, Shih-Ping Cheng
PLOS ONE , 2014, DOI: 10.1371/journal.pone.0089563
Abstract: Local anesthetics are frequently used in fine-needle aspiration of thyroid lesions and locoregional control of persistent or recurrent thyroid cancer. Recent evidence suggests that local anesthetics have a broad spectrum of effects including inhibition of cell proliferation and induction of apoptosis in neuronal and other types of cells. In this study, we demonstrated that treatment with lidocaine and bupivacaine resulted in decreased cell viability and colony formation of both 8505C and K1 cells in a dose-dependent manner. Lidocaine and bupivacaine induced apoptosis, and necrosis in high concentrations, as determined by flow cytometry. Lidocaine and bupivacaine caused disruption of mitochondrial membrane potential and release of cytochrome c, accompanied by activation of caspase 3 and 7, PARP cleavage, and induction of a higher ratio of Bax/Bcl-2. Based on microarray and pathway analysis, apoptosis is the prominent transcriptional change common to lidocaine and bupivacaine treatment. Furthermore, lidocaine and bupivacaine attenuated extracellular signal-regulated kinase 1/2 (ERK1/2) activity and induced activation of p38 mitogen-activated protein kinase (MAPK) and c-jun N-terminal kinase. Pharmacological inhibitors of MAPK/ERK kinase and p38 MAPK suppressed caspase 3 activation and PARP cleavage. Taken together, our results for the first time demonstrate the cytotoxic effects of local anesthetics on thyroid cancer cells and implicate the MAPK pathways as an important mechanism. Our findings have potential clinical relevance in that the use of local anesthetics may confer previously unrecognized benefits in the management of patients with thyroid cancer.
Evaluation of Cathodic Arc Deposited Thick CrAlSiN Coatings by Erosion Test  [PDF]
Wei-Yu Ho, Yen-Sho Chang, Bo-Yi Chou, Chien-Liang Lin
Journal of Materials Science and Chemical Engineering (MSCE) , 2015, DOI: 10.4236/msce.2015.31010

CrAlSiN with thickness up to 16 μm was deposited on tungsten carbide via multi-deposition process by cathode arc deposition technique. Scratch and water-sand jet impingement erosion tests were carried out to evaluate the adhesion by determining the worn surface of the coatings. Results showed that the failure mode of the adhesion can be concluded that the weak bond of each CrAlSiN layer as compared to the strong bond between the coating and substrate. The average surface roughness of the coatings before the erosion test was about the same level. After the erosion test of 30 minutes, the eroded CrAlSiN coatings exhibited improved average surface roughness as compared to the original CrAlSiN coatings. Further increasing the erosion up to 60 minutes, the wear and minor peeling of the CrAlSiN coating between each layer was observed. A further research to improve the bond strength between each layer was needed.

Using SiO2 Nanopowders in Anode Catalyst Layer to Improve the Performance of a Proton Exchange Membrane Fuel Cell at Low Humidity  [PDF]
Chien-Liang Lin, Shih-Chieh Hsu, Wei-Yu Ho
Journal of Materials Science and Chemical Engineering (MSCE) , 2015, DOI: 10.4236/msce.2015.31011

In this study, the transfer method is employed to add hydrophilic SiO2 nanopowders to a Pt/C catalyst ink to form an anode catalyst layer on a proton exchange membrane (PEM). The SiO2-layered membrane electrode assembly improves the performance of the PEM under low- or zero-humidification conditions. When the PEM fuel cell (PEMFC) undergoes electrochemical reaction, the moisture content of the PEM exhibits a substantial influence on the transmission of protons. To ensure the moisture content remains high, an external humidifier is typically employed to humidify the majority of PEMFCs. However, self-humidifying PEMFCs could utilize the water produced by the fuel cell reaction, thereby eliminating the need for an external humidifier. In this study, various SiO2 loadings were added to an anode catalyst layer, and the cell temperature and gas humidification conditions were adjusted to determine the influence of the SiO2 loadings on the fuel cell performance. The results show that adding SiO2 is preferable to not adding SiO2 when the fuel cell temperature is 50°C.

Schwann Cell Migration Induced by Earthworm Extract via Activation of PAs and MMP2/9 Mediated through ERK1/2 and p38
Yung-Ming Chang,Ying-Ting Shih,Yueh-Sheng Chen,Chien-Liang Liu,Wen-Kuei Fang,Chang-Hai Tsai,Fuu-Jen Tsai,Wei-Wen Kuo,Tung-Yuan Lai,Chih-Yang Huang
Evidence-Based Complementary and Alternative Medicine , 2011, DOI: 10.1093/ecam/nep131
Abstract: The earthworm, which has stasis removal and wound-healing functions, is a widely used Chinese herbal medicine in China. Schwann cell migration is critical for the regeneration of injured nerves. Schwann cells provide an essentially supportive activity for neuron regeneration. However, the molecular migration mechanisms induced by earthworms in Schwann cells remain unclear. Here, we investigate the roles of MAPK (ERK1/2, JNK and p38) pathways for earthworm-induced matrix-degrading proteolytic enzyme (PAs and MMP2/9) production in Schwann cells. Moreover, earthworm induced phosphorylation of ERK1/2 and p38, but not JNK, activate the downstream signaling expression of PAs and MMPs in a time-dependent manner. Earthworm-stimulated ERK1/2 and p38 phosphorylation was attenuated by pretreatment with U0126 and SB203580, resulting in migration and uPA-related signal pathway inhibition. The results were confirmed using small interfering ERK1/2 and p38 RNA. These results demonstrated that earthworms can stimulate Schwann cell migration and up-regulate PAs and MMP2/9 expression mediated through the MAPK pathways, ERK1/2 and p38. Taken together, our data suggests the MAPKs (ERK1/2, p38)-, PAs (uPA, tPA)-, MMP (MMP2, MMP9) signaling pathway of Schwann cells regulated by earthworms might play a major role in Schwann cell migration and nerve regeneration.
Microcrystalline-Silicon-Oxide-Based N-Type Reflector Structure in Micromorph Tandem Solar Cells
Chiung-Nan Li,Hsuan-Yin Fang,Yu-Hung Chen,Chun-Ming Yeh,Chian-Fu Huang,Yu-Chih Wang,Kai-Hsiang Hung,Yen-Yu Pan,Chien-Liang Wu,Yu-Ru Chen,Jun-Chin Liu,Chun-Heng Chen
International Journal of Photoenergy , 2012, DOI: 10.1155/2012/513238
Abstract: N-type microcrystalline silicon oxide thin films (n-c-SiO:H) have been deposited by VHF-PECVD (40 MHz) with reactant gas mixtures of CO2/SiH4 and H2. N-c-SiO thin films exhibiting low refractive index value (n600nm~2), and medium/high conductivity (≧10?9 S/cm) are suitable to be used as an “n-type reflector” in micromorph tandem solar cells. Transmission electron microscopy (TEM) results show that microstructures of n-c-SiO:H thin films contain nanocrystalline Si particles, which are randomly embedded in the a-SiO matrix. This specific microstructure provides n-c-SiO:H thin films excellent optoelectronic properties; therefore, n-c-SiO:H thin films are appropriate candidates for “n-type reflector” structures in Si tandem solar cells.
Dexamethasone to prevent postextubation airway obstruction in adults: a prospective, randomized, double-blind, placebo-controlled study
Chao-Hsien Lee, Ming-Jen Peng, Chien-Liang Wu
Critical Care , 2007, DOI: 10.1186/cc5957
Abstract: A randomized, placebo-controlled, double-blind trial was conducted in an adult medical intensive care unit of a tertiary care hospital. Eighty-six patients who had been intubated for more than 48 hours with a cuff leak volume (CLV) of less than 110 ml and who met weaning criteria were randomly assigned to receive either dexamethasone (5 mg; n = 43) or placebo (normal saline; n = 43) every six hours for a total of four doses on the day preceding extubation. CLV was measured before the first injection, one hour after each injection, and 24 hours after the fourth injection. Extubation was carried out 24 hours after the last injection. Postextubation obstruction (defined as the presence of stridor) was recorded within 48 hours of extubation.Administration of dexamethasone during the 24-hour period preceding extubation resulted in a statistically significant increase in the CLV (p < 0.05). The significant increase of CLV and change of CLV relative to baseline tidal volume (percentage) occurred not only throughout the treatment period, but also 24 hours after the last dexamethasone injection. The incidence of postextubation stridor was significantly lower in the dexamethasone group than in the placebo group (10% [4/40] versus 27.5% [11/40]; p = 0.037), whereas there was no significant difference in reintubation rate between the two groups (2.5% [1/40] versus 5% [2/40]; p = 0.561).Prophylactic administration of multiple-dose dexamethasone is effective in reducing the incidence of postextubation stridor in adult patients at high risk for postextubation laryngeal edema. The after-effect of dexamethasone may validate the reduced incidence of postextubation stridor after multiple doses of dexamethasone.NCT00452062.Laryngotracheal injury related to intubation may cause narrowing of the airway due to edema of the glottis. Laryngeal edema is more common after endotracheal intubation for more than 36 hours [1]. Edema in this region is associated with the increased risks for postex
行動學習環境中英語學習持續意圖之便利性及好奇心影響研究 The Influence of Perceived Convenience and Curiosity on Continuous English Learning Intention in Mobile Environment
Chi-Cheng Chang,Chien-Liang Lin,Chi-Fang Yan
Journal of Educational Media & Library Sciences , 2011,
Abstract: 行動學習是使用行動裝置及無線網路等行動通訊設備,搭配行動學習的數位化學習系統,使得學習者不受時間、地點的限制,以享受學習所帶來的便利性、立即性及適宜性。本研究以單組後測實驗設計以台灣中部地區125位高中學生為研究對象,在實際使用PDA進行英語學習之後,探討其持續使用意圖。研究架構上,本研究以科技接受模型為其架構,並加入學習者的知覺便利性及學習者好奇心等因素。研究結果顯示,好奇心正向影響持續使用意圖,知覺便利性正向影響知覺有用性及持續使用意圖。 Mobile learning involves the use of mobile technologies such as PDAs, Smartphones, and Wireless networks to tailor learning to a student’s cognitive ability, circumstances, and task requirements. Therefore, this study examined the influence of perceived relevance on mobile learning, and assessed whether it affected the acceptance of any particular mobile learning technology. A research study was deployed using 125 male students from a senior high school in central Taiwan. The study adopted the Technology Acceptance Model (TAM) and incorporated the factors of perceived curiosity and convenience. The results of the study revealed that perceived curiosity had a positive impact on continuous intention to use, and perceived convenience had positive effect on perceived usefulness, and continue intention to use.
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