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Search Results: 1 - 10 of 16623 matches for " Charles Douglas;Steiner "
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Plant density and nitrogen fertilization in Swiss chard
Echer, Márcia de M;Zoz, Tiago;Rossol, Charles Douglas;Steiner, Fábio;Castagnara, Deise D;Lana, Maria do C;
Horticultura Brasileira , 2012, DOI: 10.1590/S0102-05362012000400023
Abstract: an experiment was conducted to evaluate the effect of plant spacing and nitrogen fertilization on swiss chard's yield, from september to november 2009. the experimental design was of randomized blocks in split plot with four replications. in the plots were allocated the two plant spacings (0.30 and 0.50 m) and in the subplots the five doses of nitrogen (0, 40, 80, 120 and 160 kg ha-1). the crop was harvested 90 days after transplanting. the plant spacing of 0.50 m provided increased production of total fresh weight of shoot (961.7 g plant-1) and marketable (873.1 g plant-1). however, the highest total yield (77.8 t ha-1) and marketable (64.5 t ha-1) was achieved with the smaller spacing between plants (0.30 m). the n rates applied in coverage until 160 kg ha-1 increased in a linear form the total and marketable production of fresh mass of shoots, the total and marketable yield, the n content and the n accumulation in the shoots of swiss chard plants on the evaluated plant spacings.
Ananas-kultuur in Suriname
Charles Douglas
Nieuwe West-Indische Gids , 1930,
Abstract:
Aanteekeningen over de landbouw in Suriname
Charles Douglas
Nieuwe West-Indische Gids , 1928,
Abstract:
The Detection of 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanol and Ethyl Glucuronide in Human Umbilical Cord  [PDF]
Joseph Jones, Mary Jones, Charles Plate, Douglas Lewis
American Journal of Analytical Chemistry (AJAC) , 2012, DOI: 10.4236/ajac.2012.312106
Abstract: In utero exposure to ethanol continues to be a significant public health issue and neonatal healthcare professionals are in need of objective means to identify exposed newborns. The aim of this study was to fully validate two methods for the detection of two direct alcohol biomarkers, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanol (POPE) and ethyl glucuronide (EtG), in umbilical cord and apply the assays to a group of authentic specimens. The limits of detections were 2 and 1 ng/g for POPE and ETG and the limits of quantitation were 4 and 3 ng/g, respectively. Inter and intra-day precision and accuracy measurements were within 15%. The assays were applied to 308 authentic specimens where we detected POPE in five (1.6%) specimens and EtG in twelve (3.9%) specimens. The mean concentrations were 11.4 ng/g ± 9.4 ng/g and 127.2 ± 227.7 ng/g for POPE and EtG, respectively. This study suggested that umbilical cord was a suitable specimen type for the identification of newborns exposed to ethanol in the womb and the prevalence of POPE and EtG detected in umbilical cord were consistent with the prevalence of self-reported binge drinking reported by the National Birth Defect Prevention Study (NBDPS) and Behavioral Risk Factor Surveillance System (BRFSS). Further studies are required to fully describe the association between the observed concentrations of POPE and EtG in umbilical cord to the level of maternal consumption of ethanol.
The Detection of THCA Using 2-Dimensional Gas Chromatography-Tandem Mass Spectrometry in Human Fingernail Clippings: Method Validation and Comparison with Head Hair  [PDF]
Joseph Jones, Mary Jones, Charles Plate, Douglas Lewis
American Journal of Analytical Chemistry (AJAC) , 2013, DOI: 10.4236/ajac.2013.410A2001
Abstract:

Marijuana use as well as abuse is a significant public health and public safety concern in the United States and using hair to identify marijuana users and abusers has been gaining acceptance in a number of venues including workplace, court ordered, and substance abuse treatment monitoring. After the presentation of a fully validated 2-dimensional gas chromatography-tandem mass spectrometry method for the detection of 11-nor-9-carboxy-Δ9-tetrahydrocannabinol (THCA), the chief metabolite of the main psychoactive compound in marijuana, Δ9-tetrahydrocannabinol (THC), we evaluated the usefulness of fingernail clippings as an alternative specimen type to hair by the analysis of a set of 60 matched pairs of head hair and fingernail clippings. The limit of detection was 10 fg/mg, the limit of quantitation was 20 fg/mg, and the assay was linear from 20 fg/mg to 500 fg/mg. The intra- and inter-assay imprecision and bias studies at 4 different concentrations (50, 100, 500, and 1000 fg/mg) were acceptable where all % Target observations were within 16% of their expected concentrations and all %CV calculations were less than 13.5%. THCA was detectable in more fingernail specimens (53.3%) than hair specimens (46.7%) and the mean concentrations in nails were on average 4.9 times higher than in hair (1813 fg/mg and 364 fg/mg, respectively). The THCA concentrations in hair and nail were strongly associated (r = 0.974, P < 0.01, n = 60) and the association was significant. The study demonstrated that fingernail clippings are a suitable alternative specimen type to hair to monitor for marijuana use and abuse.

An exploratory study of food safety and food handling: Examining ready-to-eat foods in independent delicatessen operations  [PDF]
Douglas Murray, Charles Feldman, Lee Lee, Casey Schuckers
Advances in Bioscience and Biotechnology (ABB) , 2013, DOI: 10.4236/abb.2013.43A057
Abstract:

The US Center for Disease Control and Prevention (CDC, 2009) reports that each year 76 million cases of foodborne illness occur with over 300,000 people hospitalized and 5000 deaths. This study, phase I of a continuing study, identifies key areas for food safety improvement. This study is designed as an exploratory evaluation of independently owned and operated delicatessen operations, using Escherichia coli and Staphylococcus aureus as indicators to assess food handling and the public’s risk for pathogenic contamination from commonly served ready-to-eat/take-away foods. The analysis consisted of a comprehensive strategy of laboratory testing of samples for pathogenic contamination, informal field observation of food handling procedures, and the examination of the most recent health inspection reports for each of the 18 operations visited. The deli turkey, cream cheese and lettuce were tested using bacteria indicator plates. The results showed widespread levels of contamination. Of the 54 samples tested for Escherichia coli, 26 showed positive results which are ~45% for E. coli contamination. Of the 54 samples tested for Staphy-lococcus aureus, 31 showed positive results which are ~57% for S. aureus contamination. One issue discovered while conducting the study was the lack of consistent uniform international standards of contamination tolerance levels. The informal field observations and health report analyses revealed widespread temperature violations and numerous instances of poor food handling. The study offers independent practitioners a strategy designed to improve their health inspections scores, food handling, and mitigation of operator liability. Independent operators traditionally do not enjoy the resources of centralized supervision and expert on-staff training;

Long-Term Detection of Propofol Glucuronide in Urine Following Anesthetic Induction and Maintenance with Propofol  [PDF]
Joseph Salerno, Joseph Jones, Mary Jones, Charles Plate, Douglas Lewis
Pharmacology & Pharmacy (PP) , 2013, DOI: 10.4236/pp.2013.47076
Abstract: Propofol is the most commonly used compound for the intravenous induction and maintenance of anesthesia. Propofol addiction and abuse have become causes for concern in the healthcare community, especially among anesthesia and surgical professionals. The US Drug Enforcement Administration does not list propofol on any Schedules and most hospitals do not have inventory controls in place to prevent its misuse. Propofol is detectable in blood plasma as the parent compound for as much as 15 hours post-anesthesia. The metabolite propofol glucuronide (PPFG) has been detected in blood and urine as far out as 60 hours. Here we report the long-term renal excretion of PPFG in specimens from A) four participants following a 14-day course of orally ingested propofol dosing, and B) a female patient following anesthetic induction and 15 minutes’ maintenance with propofol. Urinary PPFG was measurable well above limits of quantitation up to 6 days following oral ingestion and 28 days post-anesthesia. We also present a third set of data evaluating the likelihood of passive exposure to aerosolized propofol in the surgical environment by analyzing the levels of urinary PPFG of healthcare workers following operating room work shifts. The results presented here demonstrate that quantitation of PPFG in urinary samples is an efficient method of long-term screening for propofol misuse and abuse.
Assessing the Suitability of the WorldClim Dataset for Ecological Studies in Southern Kenya  [PDF]
Tim J. L. Wango, Douglas Musiega, Charles N. Mundia
Journal of Geographic Information System (JGIS) , 2018, DOI: 10.4236/jgis.2018.106033
Abstract: There have been numerous efforts to generate freely available climatic datasets for use in species distribution models, the most popular being the global climatic dataset known as WorldClim. The availability of such datasets is invaluable to scientists as many studies are performed in remote areas where no weather stations are found. However, many users do not critically assess the suitability of these datasets for their applications, and errors associated with global datasets are often assumed to be negligible. Understanding what a climate dataset can or cannot deliver requires the user to have a working knowledge of what the basic spatial climate-forcing factors are at the scale of his/her study, and to have a good understanding of the uncertainty in the dataset. In geographic studies, uncertainty is often described by the degree of error (uncertainty), or degree of accuracy (certainty) in data, and thematic uncertainty refers to the uncertainty in measures made for each variable, whereas temporal uncertainty refers to the uncertainty in time period represented by each variable. Here, we used climatic data from weather stations to investigate the climate-forcing factors in southern Kenya, and then used this weather station data to investigate the uncertainty in the WorldClim dataset. Results indicated that the nineteen core Worldclim variables, known as bioclimatic variables, accurately depicted the local variations in climate in the study area. However, whereas the monthly and seasonal temperature variables represented the same time period in different locations, the same was not true for the monthly and seasonal precipitation variables. The onset of rains is a key biological indicator, and scientists studying phenomena tied to the onset of rains need to keep in mind the temporal variations represented in the WorldClim dataset.
Target volume definition in high-risk prostate cancer patients using sentinel node SPECT/CT and 18 F-choline PET/CT
Vees Hansj?rg,Steiner Charles,Dipasquale Giovanna,Chouiter Amine
Radiation Oncology , 2012, DOI: 10.1186/1748-717x-7-134
Abstract: Background To assess the influence of sentinel lymph nodes (SNs) SPECT/CT and 18 F-choline (18 F-FCH) PET/CT in radiotherapy (RT) treatment planning for prostate cancer patients with a high-risk for lymph node (LN) involvement. Methods Twenty high-risk prostate cancer patients underwent a pelvic SPECT acquisition following a transrectal ultrasound guided injection of 99mTc-Nanocoll into the prostate. In all patients but one an 18 F-FCH PET/CT for RT treatment planning was performed. SPECT studies were coregistered with the respective abdominal CTs. Pelvic SNs localized on SPECT/CT and LN metastases detected by 18 F-FCH PET/CT were compared to standard pelvic clinical target volumes (CTV). Results A total of 104 pelvic SNs were identified on SPECT/CT (mean 5.2 SNs/patient; range 1–10). Twenty-seven SNs were located outside the standard pelvic CTV, 17 in the proximal common iliac and retroperitoneal regions above S1, 9 in the pararectal fat and 1 in the inguinal region. SPECT/CT succeeded to optimize the definition of the CTV and treatment plans in 6/20 patients due to the presence of pararectal SNs located outside the standard treatment volume. 18 F-FCH PET/CT identified abnormal tracer uptake in the iliac LN region in 2/19 patients. These abnormal LNs were negative on SPECT/CT suggesting a potential blockade of lymphatic drainage by metastatic LNs with a high tumour burden. Conclusions Multimodality imaging which combines SPECT/CT prostate lymphoscintigraphy and 18 F-FCH PET/CT identified SNs outside standard pelvic CTVs or highly suspicious pelvic LNs in 40% of high-risk prostate cancer patients, highlighting the potential impact of this approach in RT treatment planning.
Liquid Chromatography-Tandem Mass Spectrometry Assay to Detect Ethyl Glucuronide in Human Fingernail: Comparison to Hair and Gender Differences  [PDF]
Joseph Jones, Mary Jones, Charles Plate, Douglas Lewis, Michael Fendrich, Lisa Berger, Daniel Fuhrmann
American Journal of Analytical Chemistry (AJAC) , 2012, DOI: 10.4236/ajac.2012.31012
Abstract: Over the past decade, the use of hair specimens for the long-term detection of the alcohol biomarker ethyl glucuronide has been increasing in popularity and usage. We evaluated the usefulness of fingernail clippings as a suitable alterna-tive to hair for ethyl glucuronide detection. A liquid chromatography-tandem mass spectrometry method for the detection of ethyl glucuronide in fingernail clippings was fully validated and used to analyze the hair and/or fingernail specimens of 606 college-aged study participants. The limit of detection was 2 pg/mg, the limit of quantitation was 8 pg/mg and the method was linear from 8 to 2000 pg/mg. Intra- and inter-assay imprecision studies at three different concentrations (20, 40, 200 pg/mg) were all within 7.8% and all intra- and inter-assay bias studies at these levels were within 115.1% of target concentration. Ethyl glucuronide levels in fingernail (mean = 29.1 ± 55.6 pg/mg) were higher than ethyl glucuronide levels in hair (mean = 9.48 ± 22.3 pg/mg) and a correlation of the matched pairs was observed (r = 0.552, P < 0.01, n = 529). Evaluating each gender separately revealed that the correlation of male fingernail to male hair was large and significant (r = 0.782, P < 0.01, n = 195) while female hair to female fingernail was small yet sig-nificant (r = 0.249, P < 0.01, n = 334). The study results demonstrated that fingernail may be a suitable alternative to hair for ethyl glucuronide detection and may be the preferred sample type due to the lack of a gender bias.
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