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Search Results: 1 - 10 of 17322 matches for " Chao Wan "
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Analytical Method and Semianalytical Method for Analysis of Scattering by Anisotropic Sphere: A Review
Chao Wan,Hongning Li
International Journal of Antennas and Propagation , 2012, DOI: 10.1155/2012/782320
Abstract: The history of methods for the electromagnetic scattering by an anisotropic sphere has been reviewed. Two main methods, angular expansion method and T-matrix method, which are widely used for the anisotropic sphere, are expressed in Cartesian coordinate firstly. The comparison of those and the further exploration on the scattering field are illustrated afterwards. Based on the most general form concluded by variable separation method, the coupled electric field and magnetic field of radial anisotropic sphere can be derived. By simplifying the condition, simpler case of uniaxial anisotropic media is expressed with confirmed coefficients for the internal and external field. Details of significant phenomenon are presented.
Hepatoprotective Diterpenoids Isolated from Andrographis paniculata  [PDF]
Wen-Wan Chao, Bi-Fong Lin
Chinese Medicine (CM) , 2012, DOI: 10.4236/cm.2012.33022
Abstract: Andrographis paniculata (Burm.f.) Nees (Acanthaceae), a plant widely used as traditional herbal medicine in many countries, has drawn attention of the researchers in recent years. Its major constituents are diterpenoids and flavonoids. This article reviews the anti-hepatotoxic effects of A. paniculata extract and derivative compounds, such as andrographolide, the major active compound, most studied for its bioactivities. Neoandrographolide shows anti-inflammatory and anti-hepatoxic properties. 14-deoxy-11,12-didehydroandrographolide and 14-deoxyabdrographolide have immunostimulatory, anti-atherosclerotic, and anti-hepatotoxic activities. The hepatoprotective activities include (1) inhibiting carbontetrachloride (CCl4), tert-butylhydroperoxide (t-BHP)-induced hepatic toxicity, (2) acting as cytochrome P450 enzymes (CYPs) inducers, (3) modulating glutathione (GSH) content, (4) influence glutathione S-transferase (GSTP) activity and phosphatidylinositol-3-kinase/Akt (PI3k/Akt) pathway, (5) synergistic effect with anti-cancer drugs induced apoptosis contributing to the bioactivities of A. paniculata extracts and isolated bioactive compounds. The articles reviewed suggest that the above compounds could be candidates for research and development as potential hepatoprotective drugs.
Establishment of Real-Time Fluorescent PCR Method for Detection of D Epizootic Hemorrhagic Disease of Deer  [PDF]
Bin Wu, Chao Wan, Liming Su, Peng Guan
Advances in Microbiology (AiM) , 2018, DOI: 10.4236/aim.2018.87032
Abstract: Epizootie hemorrhagic disease of deer virus (EHDV), is a member of the family Reoviridae virus (Orbi virus), and a double-stranded RNA virus from arthropods (mainly Culicoides), which is very similar in morphology and structure to Blue tongue virus (BTV). Serologically, there is a clear cross between the blue tongue virus and EHDV. EHD (caused by EHDV) is a seasonal, non-contact viral infectious disease. Under natural conditions, EHDV can cause infection of cattle, sheep and other domestic animals as well as many domesticated and wild ruminants such as white tail deer, Mi, large horned antelope and so on. The virus has been isolated from white-tailed deer, black-tailed deer, sheep, goats, cattle, bison and Culicoides. White tail deer infection is the most serious, and clinical characteristics are transient elevated body temperature, symptoms of shock, mucosal, serous bleeding and death in a coma [1]. At present, there is no effective vaccine and treatment for this disease. To control and eliminate EHD, it is necessary to spend a lot of manpower and material resources. Export trade is restricted, which brings great economic losses to the countries with EHD epidemic. Moreover, because of the complexity of antigen structure and the diversity of clinical symptoms of EHDV, it is difficult to diagnose in laboratory. Therefore, developing a quick and precise laboratory diagnostic method becomes more and more significant among researchers.
A New Type of Damper and Its Field Tests on Ice-coating Transmission Lines  [PDF]
Wan-li Zhong, Wei Wang, Hang-Hang Chen, Wei Luo, Yun-Chao Song
Engineering (ENG) , 2013, DOI: 10.4236/eng.2013.51B018
Abstract: The paper developed a type of damper with damping additive, of which the field tests were performed on 220kV transmission line to study its damping effects on vibration of transmission lines. First, based on the common damping measurements, a scheme of filling the damping agent in conventional damper is proposed to suppress the vibration amplitude of the phase/ground line, thus reduce the dynamic stress of the towers and lines and decrease the fatigue damage of the system. Finally, the developed dampers were installed on a 220kV transmission line in GuangdongProvince. The on-line monitoring data show that and the dampers are capable of suppressing the variation of pitch angle and yaw angle of the line, thus verify the effectiveness of the proposed damper.
WEI Chao,DUAN Wan-Suo
大气和海洋科学快报 , 2010,
Isolation and identification of bioactive compounds in Andrographis paniculata (Chuanxinlian)
Wen-Wan Chao, Bi-Fong Lin
Chinese Medicine , 2010, DOI: 10.1186/1749-8546-5-17
Abstract: Andrographis paniculata (Burm. f.) Nees (Acanthaceae) (A. paniculata, Chuanxinlian), native to Taiwan, Mainland China and India, is a medicinal herb with an extremely bitter taste used to treat liver disorders, bowel complaints of children, colic pain, common cold and upper respiratory tract infection [1-3]. The aerial part of A. paniculata is commonly used in Chinese medicine. According to Chinese medicine theory, A. paniculata 'cools' and relieves internal heat, inflammation and pain and is used for detoxication [4-6].The herb contains diterpenoids, flavonoids and polyphenols as the major bioactive components [7,8]. This article reviews the constituents and pharmacological properties of A. paniculata, including its chemical components, biological activities and possible mechanisms. The literature search was conducted in Pubmed database (1984-2010), focused on language literature in English. The keywords used were selected from andrographolide, A. paniculata and its compounds with bioactivities. In comparison with other Chinese medicinal herbs, this well studied herb not only shows a wide variety of health benefits, but many bioactive compounds are also being identified. Furthermore, several derivatives have been semi-synthesized to enhance their bioactivity than original compounds, suggesting a potential for drug development. The authors read more than 200 full articles and a total of 124 peer-reviewed papers focused on anti-inflammation, anti-cancer, immunomodulation, anti-infection, anti-hepatotoxicity, anti-atherosclerosis, anti-diabetes and anti-oxidation were selected for this review.Active compounds extracted with ethanol or methanol from the whole plant, leaf and stem [9-11] include over 20 diterpenoids and over ten flavonoids have been reported from A. paniculata [12,13]. Andrographolide (C20H30O5) is the major diterpenoid in A. paniculata, making up about 4%, 0.8~1.2% and 0.5~6% in dried whole plant, stem and leaf extracts respectively [9,11,14]. The othe
Bioactivities of major constituents isolated from Angelica sinensis (Danggui)
Wen-Wan Chao, Bi-Fong Lin
Chinese Medicine , 2011, DOI: 10.1186/1749-8546-6-29
Abstract: Angelica sinensis (Oliv.) Diels (Apiaceae) (AS), the root of which is known in Chinese as Danggui (Figure 1), was first documented in Shennong Bencao Jing (Shennong's Materia Medica; 200-300AD) and has been used as a blood tonic to treat menstrual disorders [1]. Danggui is marketed in various forms worldwide [2,3]. Over 70 compounds have been identified from Danggui, including essential oils such as ligustilide, butylphthalide and senkyunolide A, phthalide dimers, organic acids and their esters such as ferulic acid, coniferyl ferulate, polyacetylenes, vitamins and amino acids. Z-ligustilide (water insoluble and heat stable), among which Z-butylidenephthalide and ferulic acid are thought to be the most biologically active components in AS [4] and are often used in quality control and pharmacokinetic studies of Danggui [3-6].Z-ligustilide is the main lipophilic component of the essential oil constituents and a characteristic phthalide component of a number of Umbelliferae plants. Z-ligustilide is considered to be the main active ingredient of many medicinal plants, such as Danggui [7] and Ligusticum chuangxiong [8].Phthalides (Figure 2) consist of monomeric phthalides such as Z-ligustilide and phthalide dimers. In 1990 Danggui was reported in the literature when the Z-ligustilide dimer E-232 was isolated [9]. The majority of the phthalides identified is relatively non-polar, the fraction of which can be extracted with solvents such as hexanes, pentane, petroleum ether, methanol, 70% ethanol and dichloromethane. The amount of Z-ligustilide in Danggui varies between 1.26 and 37.7 mg/g dry weight [6,10,11]. Z-ligustilide facilitates blood circulation, penetrates the blood brain barrier to limit ischemic brain damage in rats and attenuates pain behaviour in mice [12-14]. Preclinical studies have indicated that AS and Z-ligustilide may also relax smooth muscle in the circulatory, respiratory and gastrointestinal systems [15].Danggui contains many organic acids. For example
Application of RVM in SoC verification and coverage-driven technology

WAN Chao,SHEN Min,

重庆邮电大学学报(自然科学版) , 2007,
Abstract: 介绍了RVM的层次化验证平台的结构,描述了RVM提供的基类和它们相互之间的关系。并且以USB 为例,给出了利用RVM搭建模块级验证平台的方法,阐述了基于代码覆盖率和功能覆盖率的覆盖率驱动技术。
Inhibitory effects of amiodarone on simvastatin metabolism in human liver microsomes

Chao Wan,Jiang wei Zhang,Ning Zhu,Ling Yang,

老年心脏病学杂志(英文版) , 2009,
Abstract: Objective To investigate the effects ofamiodarone (AMD) on simvastatin (SV) in human liver microsomes and the possible underlying mechanisms. Methods Time-, NADPH- and concentration-dependent inhibitions were tested in HLM. The logarithm of relative inhibition values was plotted versus preincubation time (0, 5, 10, 15, 20min) for a series concentration of AMD used (0, 2, 5,25, 50 μ mol/L), and the slopes determined by linear regression. These slope values represente the observed inactivation rate constants (kobs). A double-reciprocal plot was then constructed using the reciprocal of the ko~ (y-axis) and the reciprocal of the associated inhibitor concentration (x-axis) to estimate the values ofkinact and K, which were two principal kinetic constants that were specific for mechanism-based inhibition (MBI).drug-drug interactions (DDI) potential was predicted based on in vitro data and by using the in vitro-in vivo extrapolation. Results The time-, concentration- and NADPH-dependent charactga'istics confirmed that when SV was the substrate of CYP3A4, the inhibition of AMD to CYP3A4 is MBI. Kj and kinact value were calculated to be 5.1 μ mol/L and 0.018min-1 The Clint of SV was reduced 2.96-5.63 fold when it was administrated with AMD. Conclusion Based on the results, AMD would inhibit SV metabolism via the mechanism-based manner, which would lead to DDI when they are taken together. Careful clinical observation is recommended when AMD and SV have to be simultaneously prescribed.
Analyzing the Utility of a Support Pin in Sequential Robotic Manipulation
Chao Cao,Weiwei Wan,Jia Pan,Kensuke Harada
Computer Science , 2015,
Abstract: Pick-and-place regrasp is an important grasp and manipulation skill for a robot. It helps a robot to achieve tasks that cannot be achieved within a single grasp, due to constraints such as robot kinematics or collisions between the robot and the environment. Previous work on pick-and-place regrasp only leveraged flat surfaces for intermediate placements, and thus is limited in the capability to reorient an object. In this paper, we extend the reorientation capability of a pick-and-place regrasp by adding a vertical pin on the working surface and using it as the intermediate location for regrasping. In particular, our method automatically computes the stable placements of an object leaning against a vertical pin, finds several force-closure grasps, generates a graph of regrasp actions, and searches for regrasp sequences. To compare the regrasping performance with and without using pins, we evaluate the success rate and the length of regrasp sequences while performing tasks on various models. Experiments on reorientation and assembly tasks validate the benefit of using support pins for regrasp.
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