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Search Results: 1 - 10 of 40909 matches for " Chang-Shen Qiu "
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Pavlovian fear memory induced by activation in the anterior cingulate cortex
Jianrong Tang, Shanelle Ko, Hoi-Ki Ding, Chang-Shen Qiu, Amelita A Calejesan, Min Zhuo
Molecular Pain , 2005, DOI: 10.1186/1744-8069-1-6
Abstract: Pain in humans is an unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage [1]. The pain experience contains at least two major components: the first is the encoding and perception of sensory noxious stimulus (e.g., pain intensity); and the second is the encoding of the unpleasantness of the noxious stimuli [2,3]. Exploration of the centers for pain-related unpleasantness has recently been carried out in human studies using modern imaging techniques [4-8]. Among many central regions investigated, the anterior cingulate cortex (ACC) is believed to be a key structure that contributes to pain affect or unpleasantness. Early human observations showed that surgical ablation of the ACC significantly reduced pain unpleasantness without influencing the ability to detect the intensity or location of the pain [9,10]. Rainelle et al [5] reported that specific manipulation of pain unpleasantness produced significant changes in the imaged activity of the ACC, while the manipulation of pain intensity produced changes mainly in the primary somatosensory cortex (S1) [2,5]. More recently, electrophysiological recordings from the ACC in humans found that some ACC neurons respond to noxious stimuli [6]. More interestingly, a recent study reported that the ACC was also activated during social exclusion [11]. In addition to pain, the ACC has been proposed as the neurobiological substrate for executive control of cognitive and motor processes [12]. Human imaging studies demonstrate that the ACC region is activated by different factors including motivational drive, reward, gain or loss, conflict-monitoring or error prediction, and attention or anticipation [13-23]. The neuronal mechanisms for these different functions within the ACC remain mostly unknown due to the limitation of human studies.Studies from our group and other investigators, using animal models, provide evidence for the importance of the ACC in be
Metabotropic glutamate receptor 5 (mGluR5) regulates bladder nociception
Lara W Crock, Kristina M Stemler, David G Song, Philip Abbosh, Sherri K Vogt, Chang-Shen Qiu, H Henry Lai, Indira U Mysorekar, Robert W Gereau IV
Molecular Pain , 2012, DOI: 10.1186/1744-8069-8-20
Abstract: Using a combination of genetic and pharmacologic approaches, we provide evidence indicating that mGluR5 is necessary for the full expression of VMR in response to bladder distention in the absence of inflammation. Furthermore, we observed that mice infected with a uropathogenic strain of Escherichia coli (UPEC) develop inflammatory hyperalgesia to bladder distention, and that the selective mGluR5 antagonist fenobam [N-(3-chlorophenyl)-N'-(4,5-dihydro-1-methyl-4-oxo-1H-imidazole-2-yl) urea], reduces the VMR to bladder distention in UPEC-infected mice.Taken together, these data suggest that mGluR5 modulates both inflammatory and non-inflammatory bladder nociception, and highlight the therapeutic potential for mGluR5 antagonists in the alleviation of bladder pain.Interstitial cystitis/painful bladder syndrome (IC/PBS) is a serious and painful condition of unknown etiology that affects 3-6% of women in the United States [1,2]. The major clinical symptom of IC/PBS is pain upon bladder filling (distention) leading to urinary frequency and urinary urgency [3]. The current available treatments are often ineffective and do not treat the underlying pathology. Rodent bladder-injury models that induce some of the symptoms observed in IC/PBS have been used to evaluate potential treatments for IC/PBS [4-9]. One injury model, bacterial cystitis (urinary tract infection, UTI) is known to cause a similar constellation of symptoms as observed in IC/PBS (i.e. urinary frequency and urgency [10-12]). In addition, bacterial cystitis can be modeled in rodents through bladder exposure to uropathogenic Escherichia Coli (UPEC) [13,14]. Bladder infections due to UPEC are responsible for approximately 80% of UTIs in otherwise healthy women [15,16]. Understanding the underlying molecular mechanisms of both non-inflammatory bladder pain and inflammatory bladder pain due to UPEC infection could lead to the development of novel treatments for painful bladder infections as well as for IC/PBS and po
FIR Noise Prediction Algorithm and Simulation Model of Read/Write Channel in Hard Disk
硬盘读写通道的FIR噪声预测算法与仿真模型

LIU Chun,XIE Chang-Shen,HUANG Hao,
刘春
,谢长生,黄浩

计算机科学 , 2007,
Abstract: Because of the improvement of the storage density in the hard disk, and the decreased space between bits to bits, the noises in the read back signals of magnetic head have been nonstationary and correlative colored noises, which can not adapt to Viterbi detect algorithm. By embedding FIR Noise Prediction Maximum Likelihood (NPML) algo- rithm to the computing process of the branch metric in Viterbi, the colored noises can be effectively whiten. So it can be used to reduce the bit error rate (BER) and improve the system performance. In this paper the comparing analysis of the ordinary Viterbi detector, the noise prediction with FIR is given respectively. Furthermore a SIMULINK simula- tion model of read/write channel, a fast approaching way to acquire the FIR taps, and a method to verify the correction of the model have been constructed to analyze the different noise prediction algorithms. Simulation results show that under the same storage density NPML detector can attain SNR which is xxdb higher and BER which is xxdb lower than PRML detector.
APPLICATION OF FAULT TREE ANALYSIS TO RISK ASSESSMENT OF POTENTIAL WATER-INRUSH HAZARDS IN COAL MINING
基于事故树分析的煤矿潜在突水危险评价研究

WANG Chang-shen,SUN Ya-jun,HANG Yuan,
王长申
,孙亚军,杭 远

岩石力学与工程学报 , 2009,
Abstract: 基于事故致因理论建立煤矿突水事故模型.煤矿突水事故危险源被分为突水水源、突水通道、突水诱因和应急失效4类;建立煤矿突水事故树模型,并提出基于事故树方法的煤矿突水危险性专项评价方法.以杨庄矿及其周边6个地方煤矿为例,识别周边地方煤矿可能诱发杨庄矿发生地表洪水、太原组灰岩水等突水的4类突水事故危险源,并以此建立杨庄矿突水事故树模型,求最小割集评价最危险突水路径,利用最小径集优化最有效防治措施.研究结果表明,有306种可使杨庄煤矿发生煤矿突水的基本事件组合,防止杨庄矿突水事故发生的有效途径是加强监管,杜绝地方煤矿穿层、越界等违规操作.事故树方法可以完成复杂煤矿突水危险性专项安全评价.
A New Sequence Degree-based Clustering Algorithm and Dynamical ARMA Time Series Forecasting for I/O Requests
基于连续度聚类和动态ARMA时间序列预测I/O区域

LI Huai-Yang,XIE Chang-Shen,LIU Yan,ZHAO Zhen,
李怀阳
,谢长生,刘艳,赵振

计算机科学 , 2006,
Abstract: Storage system could optimize data distribution accordingly, on condition that it dynamically finds and predicts the storage areas requested frequently. So, this paper not only introduces a new sequence degree-based clustering algorithm to find the frequently accessed storage areas, but also adopts ARMA time series model to forecast the storage areas requested frequently by future I/O requests. To address the problem of accurate forecast, this paper adopts dynamic parameter estimation policy to ARMA model. The results of a large number of simulations validate the accuracy of the clustering algorithm and the preciseness of the ARMA time series model of dynamic parameter estimation policy.
Calculation of Skin Depths and Eddy-Current Power Losses for Magnetic Position Sensors
Chung-Ping Liu,Yeong-Hwa Chang,Tsung-Kun Lin,Kun-Tong Wu,Chang-Shen Yu,Der-Ray Huang,Tai-Fa Ying,Shyh-Jier Wang,

材料科学技术学报 , 2000,
Abstract: We present a theoretic model to calculate skin depths and eddy-current power losses for a magnetic position sensor. Eddy-current, arised from the operation of an alternating-current excitation, induces secondary currents and fields between magnetic material and magnetic position sensor. In this paper, a magnetic position sensor system is simplified to be an outer-winding toil along the axial direction of a low carbon steel bar. The analytical model is derived from basic field and circuit theory considering a linear approximation for a nonlinear permeability. Thus the skin depths and eddy-current power losses from the model in eddy-current modeling techniques at various frequencies of an excited current source can be calculated. The proposed configuration is capable of predicting the skin depths and eddy-current power losses for a magnetic position sensor and has a consistence with experiments.
On Human Experimentation: A Perspective of China’s Criminal Law  [PDF]
Chang-Qiu Liu
Beijing Law Review (BLR) , 2012, DOI: 10.4236/blr.2012.33014
Abstract: Human experimentation is important to the development of life science. There are so many problems brought about by human experimentation, which should be paid more attention to by law in order to protect the right of the subject. International as well as domestic laws are enacted in order to beat the illegitimate human experiment, while criminal countermeasures should be taken to redeem the failure of common legal measures, especially for China.
Distributed Robust Multi-Cell Coordinated Beamforming with Imperfect CSI: An ADMM Approach
Chao Shen,Tsung-Hui Chang,Kun-Yu Wang,Zhengding Qiu,Chong-Yung Chi
Mathematics , 2011, DOI: 10.1109/TSP.2012.2188719
Abstract: Multi-cell coordinated beamforming (MCBF), where multiple base stations (BSs) collaborate with each other in the beamforming design for mitigating the inter-cell interference, has been a subject drawing great attention recently. Most MCBF designs assume perfect channel state information (CSI) of mobile stations (MSs); however CSI errors are inevitable at the BSs in practice. Assuming elliptically bounded CSI errors, this paper studies the robust MCBF design problem that minimizes the weighted sum power of BSs subject to worst-case signal-to-interference-plus-noise ratio (SINR) constraints on the MSs. Our goal is to devise a distributed optimization method that can obtain the worst-case robust beamforming solutions in a decentralized fashion, with only local CSI used at each BS and little backhaul signaling for message exchange between BSs. However, the considered problem is difficult to handle even in the centralized form. We first propose an efficient approximation method in the centralized form, based on the semidefinite relaxation (SDR) technique. To obtain the robust beamforming solution in a decentralized fashion, we further propose a distributed robust MCBF algorithm, using a distributed convex optimization technique known as alternating direction method of multipliers (ADMM). We analytically show the convergence of the proposed distributed robust MCBF algorithm to the optimal centralized solution and its better bandwidth efficiency in backhaul signaling over the existing dual decomposition based algorithms. Simulation results are presented to examine the effectiveness of the proposed SDR method and the distributed robust MCBF algorithm.
Worst-Case SINR Constrained Robust Coordinated Beamforming for Multicell Wireless Systems
Chao Shen,Kun-Yu Wang,Tsung-Hui Chang,Zhengding Qiu,Chong-Yung Chi
Mathematics , 2011,
Abstract: Multicell coordinated beamforming (MCBF) has been recognized as a promising approach to enhancing the system throughput and spectrum efficiency of wireless cellular systems. In contrast to the conventional single-cell beamforming (SBF) design, MCBF jointly optimizes the beamforming vectors of cooperative base stations (BSs) (via a central processing unit(CPU)) in order to mitigate the intercell interference. While most of the existing designs assume that the CPU has the perfect knowledge of the channel state information (CSI) of mobile stations (MSs), this paper takes into account the inevitable CSI errors at the CPU, and study the robust MCBF design problem. Specifically, we consider the worst-case robust design formulation that minimizes the weighted sum transmission power of BSs subject to worst-case signal-to-interference-plus-noise ratio (SINR) constraints on MSs. The associated optimization problem is challenging because it involves infinitely many nonconvex SINR constraints. In this paper, we show that the worst-case SINR constraints can be reformulated as linear matrix inequalities, and the approximation method known as semidefinite relation can be used to efficiently handle the worst-case robust MCBF problem. Simulation results show that the proposed robustMCBF design can provide guaranteed SINR performance for the MSs and outperforms the robust SBF design.
Research on the Physical Attributes Evaluation Criterion of College Students  [PDF]
Yujie Shen, Jindong Chang
Advances in Physical Education (APE) , 2014, DOI: 10.4236/ape.2014.41002
Abstract:

Purpose: to improve the college students enthusiasm to participate in physical training and thus enhance students physical fitness; to provide the reference for the education administrative departments decisions and further improving the college physical teaching in our city. Methods: the paper did analysis with the sample of 19 - 22 years old college students’ health monitoring data in 2009 in Chongqing, applying the method of percentiles to establish the physical attributes evaluation criterion of college students in Chongqing. Results: develop the score sheets of single physical attributes index evaluation, comprehensive evaluation and physical attributes evaluation form for the Han college students in Chongqing. Conclusion: the physical attributes score sheets, evaluation form are applicable to the college students in Chongqing, and they can be popularized to other universities in Chongqing.

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