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Search Results: 1 - 10 of 2895 matches for " Chandra Kanti Chakraborti "
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PHYTOCHEMICAL SCREENING AND ANTIBACTERIAL ACTIVITY STUDY OF SARACA INDICA LEAVES EXTRACT
Nayak Sarojini,Sahoo Anjulata Manjari,Chakraborti Chandra Kanti
International Research Journal of Pharmacy , 2011,
Abstract: To know the role of different phytochemicals in relation to the in vitro antibacterial activity of both the ethanolic and methanolic extracts of Saraca indica (Family-Caesalpinaceae), present study was conducted. Following standard methods, phytochemical screening of each extract was performed. For antibacterial activity study, both the extracts were used at 100 μg /ml and 200 μg /ml concentrations. The largest zone of inhibition was produced when ethanolic extract (100 μg/ml and 200 μg/ml) was used against Escherichia coli, whereas the zone was least in case of Staphylococcus aureus. However, methanolic extract (100 μg /ml and 200 μg /ml) gave maximum zone of inhibition against Staphylococcus aureus and it was minimum in case of Bacillus subtilis. Although our extracts were inferior to the positive control (chloramphenicol) as far as zones of inhibition were concerned, the differences between the zones of inhibition produced by the positive control and the extracts against Escherichia coli and Bacillus subtilis were not remarkable .So, it may be noted that both the extracts, even at lower concentration, possess antibacterial activity. From the results of both the studies, it may be concluded that the ethanolic extract showed antibacterial activity was probably due to the presence of alkaloids, tannins, saponins, flavonoids and glycosides. On the other hand, due to different phytochemicals such as steroids, saponins and glycosides, the methanolic extract indicated antibacterial activity. Preliminary phytochemical studies revealed the presence of glycosides and saponins as the phytochemical classes present in both the extracts.
PHYTOCHEMICAL SCREENING AND ANTHELMINTIC ACTIVITY STUDY OF SARACA INDICA LEAVES EXTRACTS
Nayak Sarojini,Sahoo Anjulata Manjari,Chakraborti Chandra Kanti
International Research Journal of Pharmacy , 2011,
Abstract: To know the anthelmintic property of leaves of Saraca indica, we used both maceration and soxhelet methods of extraction using solvents like ethanol and methanol. Each extract was tested for its anthelmintic activity by following standard method. The ethanolic and methanolic extracts (obtained from both the methods of extractions) of Saraca indica displayed anthelmintic property in a dose-dependant manner. In both the methods of extraction, we found that the ethanolic as well as the methanolic extracts were more potent than the positive control as far as anthelminthic property was concerned. To correlate phytochemical screening with anthelmintic activity, phytochemical evaluation of the extracts was also performed. From our result, it may be mentioned that the ethanolic extract was relatively more potent as an anthelmintic agent due to the presence of alkaloids, glycosides, tannins and flavonoids. On the other hand, the methanolic extract was effective as an anthelmintic agent probably due to the involvement of glycosides and flavonoids. The presence of alkaloids, glycosides, terpenoids, tannins and flavonoids seems to be the responsible phytochemical constituents for demonstrating anthelmintic activities of our extracts.
CORRELATION BETWEEN PHYTOCHEMICAL SCREENING, ANTIBACTERIAL AND ANTHELMINTIC ACTIVITIES OF ELAEOCARPUS SERRATUS
Kayal Sriti,Sahoo Anjulata Manjari,Chakraborti Chandra Kanti
International Research Journal of Pharmacy , 2011,
Abstract: The petroleum ether, benzene, chloroform and acetone extracts of Elaeocarpus serratus were prepared by following Soxhlet method of extraction. Subsequently, phytochemical screening of the extracts was performed by following standard methods. While from the chloroform extract, alkaloids and anthraquinone glycosides were found, flavonoids and anthraquinone glycosides were present in the acetone extract. In addition, from petroleum ether extract, flavonoids were detected. On the other hand, anthraquinone glycosides were found in the benzene extract. None of the extracts showed any antibacterial and anthelmintic activities.
IN VITRO ANTIBACTERIAL ACTIVITIES STUDY OF POLYMERIC CIPROFLOXACIN SUSPENSIONS
Sahoo Subhashree,Chakraborti Chandra Kanti,Behera Pradipta Kumar
International Research Journal of Pharmacy , 2012,
Abstract: To study the in vitro antibacterial activities of mucoadhesive suspensions containing Ciprofloxacin, three different formulations were prepared by using three polymers, such as Hydroxypropyl methylcellulose (HPMC) (S1), Carbapol934 (S2) and Carbapol940 (S3), along with some common ingredients (bases). For the investigation, agar well diffusion method was performed taking Staphylococcus aureus (ATCC 25923), Bacillus subtilis and Escherichia coli (ATCC 25922). Apart from S. aureus, S1 and Ciprofloxacin in distilled water (S4) produced more or less similar zones of inhibition against all the strains used. S2 was more potent than S4 against S. aureus, while S3 was not more effective than S4 as far as their antibacterial activities were concerned. Moreover, S4 was not inferior to Ciprofloxacin in citrate buffer, marketed product containing Ciprofloxacin and Ciprofloxacin disc. The negative controls of the study, i.e., the different bases, distilled water and citrate buffer did not show any antibacterial activity. Considering the overall antibacterial activity pattern of different formulations, it may be concluded that S1 was the most potent, while S2 was more effective than S3. In addition, S1 and S4 were almost equally potent against all the strains.
IN VITRO ANTIBACTERIAL ACTIVITY STUDY OF ROSA INDICA LINN. LEAVES EXTRACTS
Sahoo Anjulata Manjari,Chakraborti Chandra Kanti,Nayak Sarojini,Kayal Sriti
International Research Journal of Pharmacy , 2011,
Abstract: To know the in vitro antibacterial activity of both the ethanolic and methanolic extracts of the leaves of both Pink Rose and Maroon Rose varieties of Rosa indica (Family-Rosaceae), present study was conducted. Both the extracts of each variety were used at 1mg/ml, 5mg/ml and 20mg/ml concentrations. While both the extracts of Pink Rose variety did not produce antibacterial activity at 1mg/ml, Staphylococcus aureus and Escherichia coli were sensitive to both the extracts at 5mg/ml and 20mg/ml in a dose-dependent manner. However, both ethanolic and methanolic extracts of Maroon Rose variety were only effective against Staphylococcus aureus at 20mg/ml. Bacillus subtilis was resistant to both the extracts of Pink Rose and Maroon Rose varieties. Moreover, like tetracycline (positive control) both the extracts of Pink Rose variety were more or less equally effective against Escherichia coli at 20 mg/ml.
IN VITRO ANTIBACTERIAL ACTIVITIES STUDY OF ALBIZZIA LEBBECK (L) BENTH LEAF EXTRACTS
Sahoo Anjulata Manjari,Chakraborti Chandra Kanti,Nayak Sarojini,Rajgaria Akshay
International Research Journal of Pharmacy , 2012,
Abstract: To know the in vitro antibacterial activities of benzene, chloroform, acetone, ethyl acetate, ethanol and methanol extracts of the leaves of Albizzia lebbek(L) Benth. (Shirish), Family: Mimosaceae, present study was conducted. All the extracts were used at 3mg/ml and 6mg/ml concentrations. Against Staphylococcus aureus, Bacillus subtilis and Escherichia coli, antibacterial activities of the different extracts were studied. Considering the overall antibacterial activity pattern, it can be mentioned that both the chloroform and ethanol extracts possessed antibacterial activities against all the strains used. Out of these two extracts, chloroform extract was more potent than the ethanol extract as far as their antibacterial activities were concerned. The extracts, which displayed antibacterial activity, produced such activity in a dose dependent manner. For the study Tetracycline (25μg/ml) was used as positive control, while DMSO was the negative control.
CORRELATION BETWEEN THE PHYTOCHEMICAL CONSTITUENTS AND ANTHELMINTIC ACTIVITY OF LAWSONIA INERMIS LEAF EXTRACTS
Nayak Sarojini,Chakraborti Chandra Kanti,Jaiswal Priyanka,Sah Usha Kumari
International Journal of Research in Ayurveda and Pharmacy , 2012,
Abstract: To know the anthelmintic activity of leaves of Lawsonia inermis, we used maceration method of extraction using solvents like ethanol and methanol. Each extract was tested for anthelminthic activity by following standard method .The ethanolic and methanolic extract displayed anthelmintic activity in dose dependant manner. We found that the ethanolic as well as methanolic extracts were more potent than the positive control as far as their anthelmintic activity was concerned. To correlate phytochemical screening with anthelmintic activity, phytochemical evaluation of the extract was also performed. From our result it may be mentioned that the ethanolic extract was potent as anthelmintic agent due to the presence of glycosides, terpenoids and flavonoids. On the other hand, the methanolic extract was effective probably due to the involvement of alkaloids, glycosides, terpenoids and flavonoids.
CORRELATION BETWEEN PHYTOCHEMICAL SCREENING AND IN VITRO ANTIBACTERIAL ACTIVITY STUDY OF ROSA INDICA LINN. LEAVES
Sahoo Anjulata Manjari,Chakraborti Chandra Kanti,Nayak Sarojini,Kayal Sriti
International Journal of Research in Ayurveda and Pharmacy , 2011,
Abstract: To know the role of different phytochemicals in relation to the in vitro antibacterial activity of both the ethanolic and methanolic extracts of Pink Rose and Maroon Rose varieties of Rosa indica leaves (Family- Rosaceae), present study was conducted. Following standard methods, phytochemical screening of each extract was performed. For antibacterial activity study, both the extracts were used at 1 mg /ml, 5 mg/ml and 20 mg /ml concentrations. From our study it seems that the Pink Rose variety was effective against both Staphylococcus aureus and Escherichia coli. Moreover, the zone of inhibition produced by this variety of rose plant and tetracycline (positive control) was found to be more or less similar against Escherichia coli. On the other hand, both the extracts of the Maroon Rose variety displayed antibacterial activity against Staphylococcus aureus only. From our antibacterial activity study, it is clear that the Pink Rose variety possesses more antibacterial activity than the Maroon Rose variety. Our phytochemical screening and antibacterial activity study indicated that alkaloids, flavonoids, saponins, tannins and phenols were present in both the extracts of the Pink Rose variety. Probably those phytochemicals were responsible for its antibacterial activity. On the other hand, the both the extracts of the Maroon Rose variety seemed to be antibacterially effective due to the presence of flavonoids, saponins, tannins, steroids and phenols.
CORRELATION BETWEEN PHYTOCHEMICAL SCREENING AND SOME BIOLOGICAL ACTIVITIES USING PLANT EXTRACTS
Nayak Sarojini,Sahoo Anjulata Manjari,Chakraborti Chandra Kanti
International Journal of Research in Ayurveda and Pharmacy , 2011,
Abstract: In order to correlate phytochemical screening with in vitro antibacterial and anthelmintic activities of the ethanolic and methanolic extracts of Saraca indica leaves, this study was undertaken. Standard methods were followed for the investigation. Tests for alkaloids, amino acids, carbohydrates, flavonoids, glycosides, saponins, proteins, steroids, tannins and triterpenoides were performed for the phytochemical evaluation of the extracts. While alkaloids, amino acids, flavonoids, glycosides, saponins, tannins and triterpenoids were detected from the ethanolic extract, amino acids, carbohydrates, flavonoids, glycosides, saponins and steroids were found in the methanolic extract. The zone of inhibition was largest when ethanolic extract (100 μg/ml and 200 μg/ml) was used against Escherichia coli, whereas it was least in case of Staphylococcus aureus. The methanolic extract (100 μg/ml and 200 μg/ml) produced maximum zone of inhibition against Staphylococcus aureus and the minimum zone was found in case of Bacillus subtilis. Chloramphenicol (positive control) produced maximum and minimum zones of inhibition against Staphylococcus aureus and Bacillus subtilis, respectively. The methanolic and ethanolic extracts of Saraca indica displayed anthelmintic property in a dose-dependant manner. We found that the methanolic as well as the ethanolic extracts had more potent anthelmintic property than the positive control (Piperazine citrate) when the extracts were obtained from both the methods of extraction.
SCANNING ELECTRON MICROSCOPY AS AN ANALYTICAL TOOL FOR PARTICLE SIZE DISTRIBUTION AND ASPECT RATIO ANALYSIS OF CIPROFLOXACIN MUCOADHESIVE POLYMERIC SUSPENSION
Subhashree Sahoo, Chandra Kanti Chakraborti, Subash Chandra Mishra & Upendra Nath Nanda
International Journal of Research and Reviews in Applied Sciences , 2011,
Abstract:
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