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Search Results: 1 - 10 of 586002 matches for " Carlos R.M.;Rebou?as "
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Holmes tremor in association with bilateral hypertrophic olivary degeneration and palatal tremor: chronological considerations. Case report
Rieder, Carlos R.M.;Rebou?as, Ricardo Gurgel;Ferreira, Marcelo Paglioli;
Arquivos de Neuro-Psiquiatria , 2003, DOI: 10.1590/S0004-282X2003000300028
Abstract: hypertrophic olivary degeneration (hod) is a rare type of neuronal degeneration involving the dento-rubro-olivary pathway and presents clinically as palatal tremor. we present a 48 year old male patient who developed holmes' tremor and bilateral hod five months after brainstem hemorrhage. the severe rest tremor was refractory to pharmacotherapy and botulinum toxin injections, but was markedly reduced after thalamotomy. magnetic resonance imaging permitted visualization of hod, which appeared as a characteristic high signal intensity in the inferior olivary nuclei on t2- and proton-density-weighted images. enlargement of the inferior olivary nuclei was also noted. palatal tremor was absent in that moment and appears about two months later. the delayed-onset between insult and tremor following structural lesions of the brain suggest that compensatory or secondary changes in nervous system function must contribute to tremor genesis. the literature and imaging findings of this uncommon condition are reviewed.
Holmes tremor in association with bilateral hypertrophic olivary degeneration and palatal tremor: chronological considerations. Case report
Rieder Carlos R.M.,Rebou?as Ricardo Gurgel,Ferreira Marcelo Paglioli
Arquivos de Neuro-Psiquiatria , 2003,
Abstract: Hypertrophic olivary degeneration (HOD) is a rare type of neuronal degeneration involving the dento-rubro-olivary pathway and presents clinically as palatal tremor. We present a 48 year old male patient who developed Holmes' tremor and bilateral HOD five months after brainstem hemorrhage. The severe rest tremor was refractory to pharmacotherapy and botulinum toxin injections, but was markedly reduced after thalamotomy. Magnetic resonance imaging permitted visualization of HOD, which appeared as a characteristic high signal intensity in the inferior olivary nuclei on T2- and proton-density-weighted images. Enlargement of the inferior olivary nuclei was also noted. Palatal tremor was absent in that moment and appears about two months later. The delayed-onset between insult and tremor following structural lesions of the brain suggest that compensatory or secondary changes in nervous system function must contribute to tremor genesis. The literature and imaging findings of this uncommon condition are reviewed.
Head tremor and progressive multifocal leukoencephalopathy in AIDS patients: report of two cases
Rieder, Carlos R.M.;Ziomkowski, Sofia C.;
Arquivos de Neuro-Psiquiatria , 2005, DOI: 10.1590/S0004-282X2005000100027
Abstract: progressive multifocal leukoencephalopathy (pml) is caused by replication of jc virus in oligodendrocytes of immunocompromised patients. common manifestations are focal motor and sensory deficits, gait abnormalities, speech and language disturbances, cognitive disorders, headache, and visual impairment. although the occurrence of movement disorders is rare in pml, bradykinesia, rigidity, dystonia, myoclonic jerks and myoclonic ataxia have been described. head tremor associated with pml has not been previously reported. we report two cases of pml in whom head tremor was present.
Reliability and validity of a scale for measurement of trunk mobility in Parkinson's disease: Trunk Mobility Scale
Franco, Clarissa R.C.;Le?o, Paula;Townsend, Raquel;Rieder, Carlos R.M.;
Arquivos de Neuro-Psiquiatria , 2011, DOI: 10.1590/S0004-282X2011000500012
Abstract: axial rigidity is an important motor manifestation in parkinson's disease (pd). trunk mobility impairment can cause gait, balance and postural problems. however, only few instruments analyze the trunk mobility in pd patients. the aim of this study is to present a new trunk mobility scale (tms) and its validation in pd. the tms constituted of dynamic tests involving trunk movements in sagittal, transversal and coronal planes. ninety eight pd patients and 31 normal controls were analyzed. a strong correlation was found between the tms scores and the hoehn & yahr staging scale (r: 0.72; p<0.01), motor unified parkinson's disease rating scale (r: 0.84; p<0.01) and schwab and england activities of daily living (r: -0.72; p<0.01). the scale showed a satisfactory reliability rate (αcronbach: 0.85, icc: 099). tms is a simple and reliable instrument to evaluate trunk mobility impairment in patients with pd.
Olfactory function and Parkinson's disease in Southern Brazil
Santin, Ricardo;Fonseca, Vicente Faraon;Bleil, Cristina Birlen;Rieder, Carlos R.M.;Hilbig, Arlete;
Arquivos de Neuro-Psiquiatria , 2010, DOI: 10.1590/S0004-282X2010000200019
Abstract: the idiopathic parkinson disease (ipd) is traditionally diagnosed by motor signs, but non-motor symptoms and signs are frequent and may help in the clinical diagnosis. purpose: to evaluate the olfactory function in brazilian healthy subjects, patients with early-onset pd (eopd) and late-onset pd (lopd) using the sniffin' sticks odor-identification test (sst). method: we studied 70 patients with ipd (19 eopd and 51 lopd) and 70 controls matched for gender, age and years of schooling. subjects with dementia and loss of smell for other reasons were excluded. results: the sst showed a significant difference (p<0.001) between groups: control groups (12.0±0.3), eopd (8.3±0.7), and lopd (6.7±0.4) when the groups were adjusted for gender, age, disease duration, and years of schooling. conclusion: both groups of ipd patients presented olfactory impairments, but those whose symptoms started before 45 years-old (eopd) had better sense of smell than the lopd patients.
Intoxica??o experimental por Asclepias curassavica (Asclepiadaceae) em bovinos. Dados complementares
Tokarnia, Carlos Hubinger;Brito, Marilene F.;Cunha, Bernardo R.M.;
Pesquisa Veterinária Brasileira , 2001, DOI: 10.1590/S0100-736X2001000100002
Abstract: in experiments in bovines, which received repeated daily sublethal doses of asclepias curassavica (2.5 and 5.0 g/kg/day during 12 days) till reaching the lethal dose or more, the fresh leaves of the plant did not show a cumulative effect. one animal developed tolerance against a dose which previously caused symptoms (5 g/kg), but not against a larger one (10 g/kg) which was given subsequently. the dried plant continued toxic up to 2 months after collection, but after 6 months had lost its toxicity. a mixture of the hacked fresh plant with fresh hacked grass, was not eaten by the animals in amounts that possibly could cause symptoms of poisoning, when given in proportions that varied from 1:2 to 1:6, plant:grass. a mixture of the recently dried hacked plant with dried hacked grass, in the proportion of 1:3, was eaten only by one of four bovines in amounts that possibly could cause symptoms; but even that animal did not show symptoms of poisoning.
Experimentos com a polpa cítrica em ovinos e coelhos
Tokarnia, Carlos Hubinger;Peixoto, Paulo Vargas;Cunha, Bernardo R.M.;
Pesquisa Veterinária Brasileira , 2001, DOI: 10.1590/S0100-736X2001000400008
Abstract: citrus pulp was fed to sheep and rabbits in high doses and during long periods, in order to find an experimental model. the citrus pulp used in the experiments in sheep was the same used by a cattle breeder in lorena, state of s?o paulo, who lost out of a total of 56 lactating cows during a period of a few weeks 5 animals by a disease characterized histologically by granulomatous lesions. the 4 sheep used in the experiments received 800g/day/animal of this citrus pulp during 10 to 11 months. they were euthanized at the end of the experiment. none of the sheep showed the clinical-pathological picture of citrus pulp poisoning seen in cattle or other alterations. in the experiments in rabbits citrus pulp of two procedures were used. in one series (6 rabbits) the same citrus pulp was given as used in the experiments in sheep; in the other series (6 rabbits) the citrus pulp used in experiments in dogs, in which it caused granulomatous lesions, was given. the rabbits of the first series ingested an average of 51.5 g/day/animal; the rabbits of the second series ingested an average of 35.2 g/kg/animal of the citrus pulp. the rabbits were euthanized 2, 3, 6 and 12 months after the beginning of the experiments. none of the rabbits showed the clinical and pathological picture of citrus pulp poisoning or any other alterations.
Intoxica o experimental por Asclepias curassavica (Asclepiadaceae) em bovinos. Dados complementares
Tokarnia Carlos Hubinger,Brito Marilene F.,Cunha Bernardo R.M.
Pesquisa Veterinária Brasileira , 2001,
Abstract: Em experimentos com bovinos, que receberam diariamente doses subletais repetidas (2,5 e 5,0 g/kg/dia durante 12 dias) até alcan ar a dose letal e/ou ultrapassá-la, A. curassavica recém-coletada n o demonstrou efeito acumulativo. Em um animal houve desenvolvimento de tolerancia contra a dose que anteriormente causou sintomas de intoxica o (5,0 g/kg), mas n o contra uma dose maior (10 g/kg). A planta dessecada continuou tóxica até 2 meses após a coleta, mas após 6 meses tinha perdido a sua toxidez. A mistura da planta fresca picada com capim fresco picado n o foi ingerida pelos animais em quantidades que pudessem causar sintomas de intoxica o, em nenhuma das propor es que variaram de 1:2 a 1:6, planta : capim. A planta recentemente dessecada picada em mistura com capim fenado picado, na propor o de 1:3, só foi consumida por um de quatro bovinos em quantidades que poderiam provocar sintomas de intoxica o; mas mesmo esse bovino n o chegou a adoecer.
Experimentos com a polpa cítrica em ovinos e coelhos
Tokarnia Carlos Hubinger,Peixoto Paulo Vargas,Cunha Bernardo R.M.
Pesquisa Veterinária Brasileira , 2001,
Abstract: Ovinos e coelhos receberam em sua alimenta o polpa cítrica em quantidades elevadas durante períodos prolongados, com a finalidade de estabelecer um modelo experimental. A polpa cítrica para os experimentos realizados nos ovinos era a mesma usada por criador do município de Lorena, SP, que perdeu 5 de um total de 56 vacas em lacta o, em um período de poucas semanas; a doen a caracterizava-se histologicamente por les es granulomatosas. Os 4 ovinos usados nos experimentos receberam 800g/dia/animal desta polpa cítrica durante 10 a 11 meses. Nenhum dos ovinos mostrou o quadro clínico-patológico da intoxica o pela polpa cítrica observado nos bovinos ou outras altera es. Nos experimentos com os coelhos foi usada polpa cítrica de duas procedências. Na primeira série de experimentos com 6 coelhos foi usada a mesma polpa cítrica dos experimentos com os ovinos; na segunda série de experimentos com mais 6 coelhos utilizou-se a polpa cítrica que causou les es granulo-matosas em c es. Os coelhos da primeira série ingeriram em média 51,5 g/dia/animal, os da segunda série em média 35,2 g/dia/animal da polpa cítrica. Os coelhos foram sacrificados 2, 3 , 6 e 12 meses após o início dos experimentos. Nenhum dos coelhos mostrou o quadro clínico-patológico da intoxica o pela polpa cítrica ou outras altera es.
Synthesis of enaminones with stationary stereochemistry
Wisniewski Junior Alberto,Oliveira Alfredo R.M.,Cunha Carlos Jorge da,Simonelli Fabio
Journal of the Brazilian Chemical Society , 1999,
Abstract: Five enaminones 4a-e derived from the reaction of 2,4,4-trimethyl-2-oxazoline anion with ethyl acetate, ethyl benzoate, ethyl cyclohexanoate, ethyl hexanoate and ethyl p-methyl benzoate, respectively, were obtained and characterized by 13C-NMR, 1H-NMR, FTIR, and mass spectral analysis. The enaminones 4a and 4b were also analysed by X-ray diffraction. Enaminone 4a crystallized in the monoclinic P2(1)/n space group with a = 9.1450(20) , b = 10.5150(20) , c = 9.5670 (20) , beta= 106.21(30)°, Z = 4. Enaminone 4b crystallized in the monoclinic P2(1)/c space group with a = 16.0520(30) , b = 26.0460(50) , c = 12.3520 (20) , beta = 111.900(30)°, Z = 4. All five enaminones were found to have an extensive pi electron delocalization and to have the same configuration where the double bond is trapped by an internal hydrogen bond between the NH and the C=O.
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