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Search Results: 1 - 10 of 52108 matches for " Carlos Esquivel-Lacroix "
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Genetic Diversity of Great Dane Breed Using Ten Microsatellites: Impact of Breeding Control over the Breeding Line  [PDF]
Gino Noris, Carla Santana, Mariana Herrán-Aguirre, Marco Antonio Meraz-Ríos, Mario Pérez-Martínez, Carlos Esquivel-Lacroix, Leonor C. Acosta-Saavedra, Eduardo Rodríguez, María de la Paz Juaréz, Emma S. Calderón-Aranda, Rocío Gómez
Open Journal of Genetics (OJGen) , 2014, DOI: 10.4236/ojgen.2014.42011
Abstract:

The American Kennel Club and the Fédération Cynologique Internationale recognize two phenotypic variants of Great Dane breed denominated American and European varieties. Historically, these varieties have been segregated according to morphological characteristics. In an attempt to obtain a better characterization, breeders have been interested in the genetic parameters that could evaluate the within-breed diversity. In this document, we studied the genetic structure of Great Dane breed with 10 STR markers in 88 dogs using capillary electrophoresis. Cluster analysis, population differentiation and phylogenetic analyses revealed that American and European varieties are genetically independent. Nevertheless, within the American variety a genetic stratification was found. Additionally, a high misclassification (28%) was detected, which could be due to wrong registration or false paternity. Our results support the importance to deem genetic markers as useful tools in breeding control. Similarly, these studies serve as an accurate reference to establish standards by dog breeding associations and for choosing among dogs for inter-breeding. Nevertheless, genetic tools are only a complement of morphological methods, since both are reshuffling the control over the breeding line. Notwithstanding, this database provides an overall and scape concerning the impact of genetic diversity within-breed. Unmistakably, more databases are needed to increase the quality of the breeding line as well as the number of STR in order to study, with more detail, the genetic structure in the Great Dane race.

Dosimetric Comparison of Craniospinal Axis Irradiation (CSI) Treatments Using Helical Tomotherapy, SmartarcTM, and 3D Conventional Radiation Therapy  [PDF]
Pamela Myers, Sotirios Stathakis, Alonso N. Gutiérrez, Carlos Esquivel, Panayiotis Mavroidis, Niko Papanikolaou
International Journal of Medical Physics,Clinical Engineering and Radiation Oncology (IJMPCERO) , 2013, DOI: 10.4236/ijmpcero.2013.21005
Abstract:
Purpose: Craniospinal axis irradiation (CSI) is a method of treating various central nervous system malignancies. The large target volume typically includes entire spinal cord and whole brain. Dosimetric comparison was performed between tomotherapy, volumetric modulated arc therapy (VMAT), and 3D conformal radiation therapy (3D-CRT) for CSI. Methods and Materials: Five (n = 5) CSI patients were planned using 3D-CRT, VMAT, and tomotherapy (normalized such that 95% of PTV received at least 23.4 Gy in 13 fractions). Plans were compared using PTV conformity number (CN) and homogeneity index (HI), normal tissue (NT) dose statistics, integral dose, and treatment time. Results: On average, tomotherapy plans showed higher CN (0.932 vs. 0.860 and 0.672 for SmartArc and 3D-CRT). In terms of HI, VMAT plans consistently showed better dose homogeneity (1.07 vs. 1.15 and 1.13 for tomotherapy and 3D-CRT). SmartArc delivered lower maximum dose for majority of NT, but higher mean dose. 3D-CRT plans delivered higher maximum dose but lower mean dose to NT. Conclusions: SmartArc treatments achieved better PTV homogeneity and reduced maximum dose to NT. Tomotherapy showed better target conformity, but 3D-CRT was shown to reduce mean dose to NT. Integral doses were similar between treatment modalities, but tomotherapy treatment times were much longer.
Accuracy of the Small Field Dosimetry Using the Acuros XB Dose Calculation Algorithm within and beyond Heterogeneous Media for 6 MV Photon Beams  [PDF]
Sotirios Stathakis, Carlos Esquivel, Luis Vazquez Quino, Pamela Myers, Oscar Calvo, Panayiotis Mavroidis, Alonso N. Gutiérrez, Niko Papanikolaou
International Journal of Medical Physics,Clinical Engineering and Radiation Oncology (IJMPCERO) , 2012, DOI: 10.4236/ijmpcero.2012.13011
Abstract: Purpose: The dosimetric accuracy of the recently released Acuros XB advanced dose calculation algorithm (Varian Medical Systems, Palo Alto, CA) is investigated for single radiation fields incident on homogeneous and heterogeneous geometries, as well as for two arc (VMAT) cases and compared against the analytical anisotropic algorithm (AAA), the collapsed cone convolution superposition algorithm (CCCS) and Monte Carlo (MC) calculations for the same geometries. Methods and Materials: Small open fields ranging from 1 × 1 cm2 to 5 × 5 cm2 were used for part of this study. The fields were incident on phantoms containing lung, air, and bone inhomogeneities. The dosimetric accuracy of Acuros XB, AAA and CCCS in the presence of the inhomogeneities was compared against BEAMnrc/DOSXYZnrc calculations that were considered as the benchmark. Furthermore, two clinical cases of arc deliveries were used to test the accuracy of the dose calculation algorithms against MC. Results: Open field tests in a homogeneous phantom showed good agreement between all dose calculation algorithms and MC. The dose agreement was +/?1.5% for all field sizes and energies. Dose calculation in heterogenous phantoms showed that the agreement between Acuros XB and CCCS was within 2% in the case of lung and bone. AAA calculations showed deviation of approximately 5%. In the case of the air heterogeneity, the differences were larger for all calculations algorithms. The calculation in the patient CT for a lung and bone (paraspinal targets) showed that all dose calculation algorithms predicted the dose in the middle of the target accurately; however, small differences (2% - 5%) were observed at the low dose region. Overall, when compared to MC, the Acuros XB and CCCS had better agreement than AAA. Conclusions: The Acuros XB calculation algorithm in the newest version of the Eclipse treatment planning system is an improvement over the existing AAA algorithm. The results are comparable to CCCS and MC calculations especially for both stylized and clinical cases. Dose discrepancies were observed for extreme cases in the presence of air inhomogeneities.
Características epidemiológicas y percepción de la población que asiste a los Equipos Básicos de Atención Integral en Salud (EBAIS)
Ramos-Esquivel,Allan; León-Céspedes,Carlos;
Acta Médica Costarricense , 2008,
Abstract: aim: epidemiological characteristics of the patients who attend the basic teams of global health attention( equipos básicos de atención integral en salud, known as ebais) are little known. the perception about the attention received at the social security centers in costa rica is also overlooked. objective: to find out the socio-economical characteristics and patients? satisfaction in each health region. methods: the data from the first national health interview (2006) were analyzed with the statistic program spss (statistical package for the social sciences) viewer 12.0 for windows?. some variables such as age, sex, nationality, health region, social security coverage, income and attention quality, were adjusted according to the population who were seen at the one ebais during the study period. results: seventy one percent of the inhabitants of costa rica, during the study period had attended an ebais, out of which 97.5% were costarricans. besides, 70% perceived an income less than two hundred thousand "colones" a month. fifty percent of the population had not attended high-school. the attention received at the ebais was perceived as good or excellent by a 66%. conclusion: attention quality received by the patients who attended an ebais was good or excellent; there were few cases of patients who complained about the attention received. at the same time, these patients are characterized by their low education level and their limited income.
Efectos no hipolipemiantes de las estatinas
Ramos-Esquivel,Allan; León-Céspedes,Carlos;
Acta Médica Costarricense , 2007,
Abstract: statins have become one of the most prescribed drugs in theworld.this medications are in the treatment of dyslipidemia and in the prevention of cardiovascular diseases. recently, new evidence has emerged about their mechanisms of action and their pleiotropic properties well beyond lowering cholesterol levels. this pharmacodynamic action has called the attention of many investigators who suggest their use in several diseases centered on inflammation, immune disorders and cell proliferation. although there is wide evidence that recognizes its efficacy in several disease models, there is still a lack of studies to approve their use in clinical practice. we present a review of their pharmacodynamic properties focusing on the pathophysiology that suggests their clinical use in the treatment of several diseases.
Amonoideos y bivalvos del Sinemuriano Superior en un nuevo afloramiento de la Formación Huayacocotla, Hidalgo, México, algunas consideraciones paleoambientales
Arenas Islas, Diana;Esquivel Macías, Carlos;Flores-Castro, Kinardo;
Boletín de la Sociedad Geológica Mexicana , 2009,
Abstract: to the east hidalgo state, mexico, the tenango de doria county is the main mountain valley with outcrops of the huayacocotla formation (upper sinemurian). a new outcrop with great abundance of ammonoids and bivalves is here reported. specimens were identified to the generic and specific level, including analysis of their functional morphology, hábitat spectra, index of relative abundance and measures, with emphasis on paleoecological inferences. sedimentary petrology was also described. species found in this outcrop include: paltechioceras tardecrecens, p. rothpletzi, p. burckhardti, p. harbledownense, paltechioceras sp, orthechioceras jamesdanae, o. incaguasiense, o. pauper, plesechioceras cihuacoatle, arnioceras ceratitoides, aff metophioceras sp., neocrassina sp, plagiostoma sp, bositra sp, ?parainoceramus sp, posodonotis semiplicata, one species of cryptodonta and 3 species not identified. neocrassina and an unnamed species represent infaunal elements and suggest existence of soft bottom sea. the environmental preference analysis is based on morpho-functional information from fossil material, and suggests the main facies to correspond to inner and proximal platform. the faunal composition of the outcrop was broadly dominated by ammonoids. this observation is reinforced by diversity index. these proxys and the index hábitat with the measured structure are indicative for a median neritic platform too. the fossil assemblages include some characteristics that recall jurassic communities previously described, however it possibly represent a new type of jurassic community. posodonotis semiplicata is consistent with low oxygen bottom waters, interpretation reinforced by presence of pyrite nodules. the taphonomic evidence of the outcrop reveals the low energy distal neritic platform, alternated with sedimentary soft flows from proximal neritic and medial platform.
Muerte precoz en la hemorragia subaracnoidea aneurismática
Lacerda Gallardo,ángel J; Estenoz Esquivel,Juan Carlos;
Revista Cubana de Cirug?-a , 1998,
Abstract: an observational-descriptive study was conducted on all the patients over 15 who had died from an aneurysmal subarachnoid hemorrhage and had been previously examined from the anatomical and pathological viewpoints in general teaching hospital of moron municipality from january 1st, 1986 to december 31st, 1996. 19 patients were diagnosed with aneurysmal subarachnoid hemorrhage (ash) throughout this period; 7 of them (36.84 %), 3 males and 4 females with average age 48.86 years-old, died without medical treatment in the community and our study focused on these cases. 71.43 % of patients suffered from blood hypertension and 100 % of the examined brains presented aneurysmal sacs located in the anterior segment of willi's circle. anatomical and pathological findings revealed the presence of ventricular flooding in all the cases whereas the most noted extraneurological anomaly was pulmonary edema and congestion affecting 5 patients (71.43 %)
Odonata of Costa Rica: Diversity and checklist of species
Ramírez,Alonso; Paulson,Dennis R.; Esquivel,Carlos;
Revista de Biología Tropical , 2000,
Abstract: an updated list of the odonata of costa rica is presented containing 268 species. since the last published list for the country, 41 additional species have been reported. the country is the best studied in central america. the most species-rich families are libellulidae, coenagrionidae, gomphidae, and aeshnidae, together comprising ~75% of the total fauna. most species in the country are also found in south america, indicating a tendency for wide ranges rather than endemism. however, about a fifth of the species appear to be endemic to the costa rica-panama region. estimates of the range of the proportion of total world species occurring in costa rica lead to predictions of a range of 5600-9000 species of odonata worldwide.
Efectos no hipolipemiantes de las estatinas
Allan Ramos-Esquivel,Carlos León-Céspedes
Acta Médica Costarricense , 2007,
Abstract: Las estatinas se han convertido en una de las drogas más prescritas en el mundo. Este tipo de fármacos es utilizado en el tratamiento de la dislipidemia y en la prevención de la enfermedad cardiovascular. Recientemente ha surgido nueva evidencia sobre sus mecanismos de acción y son bien conocidas sus propiedades pleiotrópicas, más allá de la disminución de los niveles de colesterol. Esta característica farmacodinámica ha llamado la atención de muchos investigadores quienes sugieren su uso en diferentes enfermedades que se centran en la inflamación, en desórdenes de la inmunidad y en la proliferación celular. Aunque hay amplia evidencia que reconoce su eficacia en diversos modelos de enfermedades, todavía existe una falta de estudios que apoyen su uso en la práctica clínica. En este trabajo se revisa el mecanismo de acción de estos fármacos y de la base fisiopatológica que sugiere su uso clínico en diferentes enfermedades. Statins have become one of the most prescribed drugs in theworld.This medications are in the treatment of dyslipidemia and in the prevention of cardiovascular diseases. Recently, new evidence has emerged about their mechanisms of action and their pleiotropic properties well beyond lowering cholesterol levels. This pharmacodynamic action has called the attention of many investigators who suggest their use in several diseases centered on inflammation, immune disorders and cell proliferation. Although there is wide evidence that recognizes its efficacy in several disease models, there is still a lack of studies to approve their use in clinical practice. We present a review of their pharmacodynamic properties focusing on the pathophysiology that suggests their clinical use in the treatment of several diseases.
Características epidemiológicas y percepción de la población que asiste a los Equipos Básicos de Atención Integral en Salud (EBAIS) (Epidemiological characteristics and perception of patients seen at the Basic Teams of Global Health Care (EBAIS in Costa Rica)
Allan Ramos-Esquivel,Carlos León-Céspedes
Acta Médica Costarricense , 2008,
Abstract: Justificación y objetivos: Son poco conocidas las principales características socioeconómicas de los pacientes que asisten a los Equipos Básicos de Atención Integral en Salud (EBAIS), así como su percepción sobre la atención recibida en los centros asistenciales de la Caja Costarricense de Seguro Social. El principal objetivo de este estudio es describir tales características y el grado de satisfacción de los pacientes por la atención recibida en dichos centros. Metodología: Se utilizaron los datos obtenidos de la Primera Encuesta Nacional de Salud de 2006 y se analizaron con el programa estadístico SPSS. (Statistical Package for the Social Sciences), viewer 12.0 for Windows . Se ajustaron las variables: como edad, sexo, nacionalidad, región de salud, cobertura de seguro social, escolaridad, ingreso y calidad de la atención recibida, para la población que se aló haber asistido a un EBAIS. Resultados: Un 71.3% de los habitantes del territorio nacional durante el período de estudio había utilizado los Equipos Básicos de Atención Integral en Salud; 97.5% de ellos eran de nacionalidad costarricense. Además, un 70% del total, percibía un ingreso menor a los doscientos mil colones mensuales. Con respecto a su nivel educativo, un 50% no cuenta con educación secundaria. La atención recibida en el EBAIS fue catalogada por un 66% de los pacientes como buena o excelente. Conclusión: La mayoría de los pacientes que asisten a los EBAIS consideran la atención recibida como buena o excelente, y pocos se quejan al respecto. A su vez, estos pacientes se caracterizan por su bajo nivel educativo y salarial. Aim: Epidemiological characteristics of the patients who attend the Basic Teams of Global Health Attention( Equipos Básicos de Atención Integral en Salud, known as EBAIS) are little known. The perception about the attention received at the Social Security Centers in Costa Rica is also overlooked. Objective: To find out the socio-economical characteristics and patients’ satisfaction in each Health Region. Methods: The data from the First National Health Interview (2006) were analyzed with the statistic program SPSS (Statistical Package for the Social Sciences) viewer 12.0 for Windows . Some variables such as age, sex, nationality, health region, social security coverage, income and attention quality, were adjusted according to the population who were seen at the one EBAIS during the study period. Results: seventy one percent of the inhabitants of Costa Rica, during the study period had attended an EBAIS, out of which 97.5% were costarricans. Besides, 70% perceived an i
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