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Search Results: 1 - 10 of 5318 matches for " Candice Anderson "
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Molecular Markers Associated with Ph-3 Gene Conferring Late Blight Resistance in Tomato  [PDF]
Dilip R. Panthee, Randy G. Gardner, Ragy Ibrahem, Candice Anderson
American Journal of Plant Sciences (AJPS) , 2015, DOI: 10.4236/ajps.2015.613216
Abstract: Late blight (LB), caused by the oomycete Phytophthora infestans, is one of the most devastating diseases of tomato. Three major genes Ph-1, Ph-2 and Ph-3 conferring resistance to LB have been identified and mapped to the chromosomes 7, 10 and 9, respectively. However, PCR-based molecular markers associated with these genes are limited. Molecular markers are extremely useful in the screening and selection of tomato lines for the development of LB resistant genotypes. The objective of this study was to identify molecular markers associated with Ph-3 gene conferring LB resistance in tomato. Four co-dominant markers were found to be associated with Ph-3, all of which were sequence characterized amplified region (SCAR) type. Breeding lines and cultivars were inoculated with a field isolate of Phytophthora infestans to collect phenotypic data on disease resistance. Genotypic data from molecular markers associated with Ph-3 were in close agreement with the phenotypic data for the lines tested. With the verification of genotypic data from novel molecular markers in known genotypes supported by phenotypic data, the novel molecular markers may be useful in screening tomato populations aiming to develop LB resistant genotypes or cloning the LB resistant genes.
Diallel Analysis for Lycopene Content in the Hybrids Derived from Different Colored Parents in Tomato  [PDF]
Dilip R. Panthee, Penelope Perkins-Veazie, Candice Anderson, Ragy Ibrahem
American Journal of Plant Sciences (AJPS) , 2015, DOI: 10.4236/ajps.2015.69147
Abstract: Lycopene is a red pigment in tomato with purported antioxidant properties. As the amount of lycopene has been reported to differ in different colored tomatoes or even absent in non-red tomatoes, the objective of this study was to investigate the inheritance of lycopene content and the color parameters of hybrids using a 10 parent diallel excluding reciprocals. Parents differed in general combining ability (GCA) for lycopene and color parameters. “Chocolate Stripe” (purple and brown striped) had the highest lycopene content followed by NC 1CS (red colored with the crimson gene) with the best general combining ability among parental lines. Hybrids differed in lycopene content and color parameters across two summer and greenhouse experiments, with no interaction between experiments indicating that the lycopene content was consistent. Narrow-sense heritability for lycopene was only 9% whereas broad-sense heritability was estimated to be 25%. The order of dominance for lycopene content was found as purple-brown > red > blue > yellow > green. Heritability estimates for color parameters were close to those for lycopene. This information may be useful in developing specialty type tomatoes or increasing lycopene content in tomatoes.
HLA-DM Mediates Epitope Selection by a “Compare-Exchange” Mechanism when a Potential Peptide Pool Is Available
Andrea Ferrante, Matthew W. Anderson, Candice S. Klug, Jack Gorski
PLOS ONE , 2008, DOI: 10.1371/journal.pone.0003722
Abstract: Background HLA-DM (DM) mediates exchange of peptides bound to MHC class II (MHCII) during the epitope selection process. Although DM has been shown to have two activities, peptide release and MHC class II refolding, a clear characterization of the mechanism by which DM facilitates peptide exchange has remained elusive. Methodology/Principal Findings We have previously demonstrated that peptide binding to and dissociation from MHCII in the absence of DM are cooperative processes, likely related to conformational changes in the peptide-MHCII complex. Here we show that DM promotes peptide release by a non-cooperative process, whereas it enhances cooperative folding of the exchange peptide. Through electron paramagnetic resonance (EPR) and fluorescence polarization (FP) we show that DM releases prebound peptide very poorly in the absence of a candidate peptide for the exchange process. The affinity and concentration of the candidate peptide are also important for the release of the prebound peptide. Increased fluorescence energy transfer between the prebound and exchange peptides in the presence of DM is evidence for a tetramolecular complex which resolves in favor of the peptide that has superior folding properties. Conclusion/Significance This study shows that both the peptide releasing activity on loaded MHCII and the facilitating of MHCII binding by a candidate exchange peptide are integral to DM mediated epitope selection. The exchange process is initiated only in the presence of candidate peptides, avoiding possible release of a prebound peptide and loss of a potential epitope. In a tetramolecular transitional complex, the candidate peptides are checked for their ability to replace the pre-bound peptide with a geometry that allows the rebinding of the original peptide. Thus, DM promotes a “compare-exchange” sorting algorithm on an available peptide pool. Such a “third party”-mediated mechanism may be generally applicable for diverse ligand recognition in other biological systems.
Pharyngeal trauma: Two unique case reports  [PDF]
Candice Colby, Charles Moore
Open Journal of Clinical Diagnostics (OJCD) , 2012, DOI: 10.4236/ojcd.2012.23013
Abstract: The neck is a complex pathway for numerous critical structures and is defined by layers of fascial planes and spaces. Traumatic interruption of these planes can occur with injury to any of the mucosal structures within the head and neck, and is often seen as a consequence of pharyngeal injury. Here, the identification and management of two interesting and unique cases of penetrating oropharyngeal trauma are discussed: oropharyngeal trauma following abuse, and a self-inflicted pharyngeal wound with subsequent foreign body ingestion. We also review the literature regarding diagnosis, treatment, and management of traumatic pharyngeal perforation, and discuss possible complications.
Ancient DNA from lake sediments: Bridging the gap between paleoecology and genetics
Lynn L Anderson-Carpenter, Jason S McLachlan, Stephen T Jackson, Melanie Kuch, Candice Y Lumibao, Hendrik N Poinar
BMC Evolutionary Biology , 2011, DOI: 10.1186/1471-2148-11-30
Abstract: We successfully sequenced DNA from 64 samples (out of 126) comprised of bulk sediment and seeds, leaf fragments, budscales, and samaras extracted from Holocene lake sediments in the western Great Lakes region of North America. Overall, DNA yields were low. However, we were able to reliably amplify samples with as few as 10 copies of a short cpDNA fragment with little detectable PCR inhibition. Our success rate was highest for sediments < 2000 years old, but we were able to successfully amplify DNA from samples up to 4600 years old. DNA sequences matched the taxonomic identity of the macrofossil from which they were extracted 79% of the time. Exceptions suggest that DNA molecules from surrounding nearby sediments may permeate or adhere to macrofossils in sediments.An ability to extract ancient DNA from Holocene sediments potentially allows exciting new insights into the genetic consequences of long-term environmental change. The low DNA copy numbers we found in fossil material and the discovery of multiple sequence variants from single macrofossil extractions highlight the need for careful experimental and laboratory protocols. Further application of these protocols should lead to better understanding of the ecological and evolutionary consequences of environmental change.Knowledge of the long term population history of a plant species provides clues to its current distribution [1-5], abundance [2,6] and genetic structure, [7-11], and can also help assess its potential response to future environmental change [12,13]. Ecological and biogeographic history have been inferred primarily from paleoecological studies (fossil pollen and macrofossils in sediments of lakes and peatlands, middens accumulated by packrats and other rodents, tree-rings from living and dead trees) and phylogeographic studies (spatial patterns of molecular and other genetic markers in living populations). These records indicate that terrestrial plant species have undergone population expansion, cont
Chomsky e a linguística cartesiana
Glenday, Candice;
Trans/Form/A??o , 2010, DOI: 10.1590/S0101-31732010000100009
Abstract: this paper intends to present and critically examine some of the main arguments provided by the north-american linguist noam chomsky to support the thesis of an innate origin of a universal grammar, which is commonly associated with the rationalist philosophical tradition, as the only possible explanation of the specific features of human language and its acquisition around early childhood. some criticisms made by thomas nagel on chomsky's so-called biological innatism will be then examined, and at the end of the paper we shall defend chomsky's arguments in favor of his innatism.
Alternative therapies for the holistic care of the HIV / AIDS patient: overview
Candice Bodkin
Health SA Gesondheid , 2003,
Abstract: The holistic nursing care of individuals infected with HIV / AIDS involves promoting psychological and physiological well-being as well as fostering socio-cultural relationships and supporting the fulfilment of spiritual aspirations. HIV / AIDS is a complex disease requiring complex holistic nursing care. The allopathic management of HIV / AIDS takes a biomedical approach and includes treatment with highly active antiretroviral therapy (HAART). HAART is not entirely beneficial on it own. Alternative therapies can be used as an adjunct to HAART. Alternative therapies provide a means of providing holistic nursing care to HIV / AIDS infected individuals and thus ensuring overall wellbeing of the HIV / AIDS infected individual. Alternative therapies that can be used for the holistic nursing care of HIV / AIDS infection include psychological, mental and emotional therapies, therapeutic touch, nutrition, vitamins, minerals and nutritional supplements, herbal medicine, Chinese medicine and homeopathy, traditional medicine, lifestyle changes and fostering spiritual well-being. This article provides an overview of alternative therapies that can be used in the holistic nursing care of the HIV / AIDS patient. Die holistiese verpleegsorg van individue met HIV / VIGS behels die bevordering van psigologiese en fisiologiese welsyn, sowel as die bevordering van sosio-kulturele verhoudings ten einde geestelike strewes te verwesenlik. HIV / VIGS is 'n komplekse siektetoestand wat komplekse holistiese verpleegsorg vereis. Die alopatiese behandeling van HIV / VIGS impliseer die gebruik van 'n biomediese benadering sowel as die toediening van hoogs aktiewe antiretrovirale terapie (HAART). HAART in isolasie toegedien, is nie volkome voordelig nie. Alternatiewe terapie kan saam met HAART benut word. Die gebruik van alternatiewe terapie stel verpleegkundiges in staat om holistiese verpleegsorg vir die HIV / VIGS-pasi nt aan te bied, aangesien dit tot die algehele welsyn van die HIV/ VIGS-pasi nt bydra. Alternatiewe terapie wat gebruik kan word in die holistiese verpleegsorg van die HIV / VIGS-pasi nt sluit in psigologiese terapie, terapeutiese aanraking, voeding, vitamiene, minerale-en voedingsaanvullings, kruiemedikasie, Chinese medikasie, homeopatie, tradisionele medisyne, lewenstylverandering en geestelike welsyn. Hierdie artikel verskaf 'n oorsig van die alternatiewe terapie wat benut kan word in die holistiese verpleegsorg van die HIV / VIGS-pasi nt. (Health SA Gesondheid: interdisciplinary research journal: 2003 8(3): 37-46)
Library Liaison with non-academic units: a new application for a traditional model
Candice Dahl
Partnership : the Canadian Journal of Library and Information Practice and Research , 2007,
Abstract: This paper suggests that traditional models of liaison librarianship, which focuson liaison with academic units such as teaching departments and specificcolleges within institutions, should be adapted and then expanded to include nonacademicunits as well. Although the literature demonstrates that understandingsof liaison work have evolved, it still contains almost no examples of how toextend library liaison beyond traditional academic units in a systematic way. As aresult, existing liaison programs are too narrowly conceived, and the strengths ofthe liaison model are not being fully exploited. By adapting the structures in placeto support traditional liaison, such programs can be expanded to include nonacademicunits as well. As a result, libraries gain opportunities for broadercollaboration on campus. Suggestions for identifying targets for formal nonacademicliaison are provided, as are guidelines for determining suitable liaisonactivities and ensuring administrative support within the library.
Alternative therapies for the holistic care of the HIV/AIDS patient
Candice Bodkin
Health SA Gesondheid , 2003, DOI: 10.4102/hsag.v8i3.133
Abstract: The holistic nursing care of individuals infected with HIV/AIDS involves promoting psychological and physiological well-being as well as fostering socio-cultural relationships and supporting the fulfilment of spiritual aspirations. Opsomming Die holistiese verpleegsorg van individue met HIV/VIGS behels die bevordering van psigologiese en fisiologiese welsyn, sowel as die bevordering van sosio-kulturele verhoudings ten einde geestelike strewes te verwesenlik. *Please note: This is a reduced version of the abstract. Please refer to PDF for full text.
Matière à controverse Grounds for Controversy: the Argument Surrounding the Publication of Documents diplomatiques et consulaires relatifs à l’histoire du Liban
Candice Raymond
Ateliers du LESC , 2012, DOI: 10.4000/ateliers.9042
Abstract: Cet article a pour objet la polémique qui a opposé entre les années 1980 et 2000 Adel Ismail, historien et diplomate libanais ayant édité une vaste collection de documents diplomatiques fran ais relatifs à l’histoire moderne du Liban, et Antoine Hokayem, historien universitaire à l’origine d’une critique virulente de ces publications et lui-même éditeur de recueils d’archives. L’analyse des différentes séquences du processus polémique vise à identifier les types de manipulation auxquels ces documents ont été soumis depuis leur collecte jusqu’à leur usage polémique et à étudier leurs modes d’articulation avec les logiques historiographiques, politiques et économiques qui en ont sous-tendu le développement. L’examen des dispositifs éditoriaux adoptés par les protagonistes de la polémique mettra en lumière leur r le dans le déroulement de cette dernière et les effets produits par la matérialité même de ces dispositifs. The subject of this article is the 1980-2000 controversy between Adel Ismail, a Lebanese historian and diplomat who has published a vast collection of French diplomatic documents relating to the modern history of Lebanon, and Antoine Hokayem, an academic historian behind a virulent critique of these publications, himself also the publisher of archive collections. The different stages of the controversy are analysed with the aim of identifying the types of manipulations to which these documents were subjected, from the time they were collected until they were used for polemical purposes, and to study the ways in which they connect with the historiographical, political and economic rationales that underlay their development. An examination of the editorial apparatuses adopted by the controversy’s protagonists will shed light on their role in its development and the effects produced by the very materiality of these apparatuses.
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