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Search Results: 1 - 10 of 19256 matches for " CRISTINA;LEGEY "
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Desafios e oportunidades da era do conhecimento
LASTRES, HELENA MARIA MARTINS;ALBAGLI, SARITA;LEMOS, CRISTINA;LEGEY, LIZ-REJANE;
S?o Paulo em Perspectiva , 2002, DOI: 10.1590/S0102-88392002000300009
Abstract: this article addresses the need to identify the main characteristics of the information age, as well as to monitor and guide the new standards for accumulating and disseminating knowledge. it further underscores the urgency of developing new policy tools to manage the challenges and enhance the opportunities associated with brazil's entrance into the information age.
Specific antibody levels and antigenic recognition of Wistar rats inoculated with distinct isolates of Trypanosoma evansi
Queiroz, Adriana O;Legey, Ana P;Xavier, Samanta CC;Jansen, Ana M;
Memórias do Instituto Oswaldo Cruz , 2001, DOI: 10.1590/S0074-02762001000700014
Abstract: "mal de cadeiras", an enzootic disease caused by trypanosoma evansi, is one of the most important trypanosomiases in the brazilian pantanal region. the disease affects mainly horses, which are widely used in extensive cattle production, an activity of greatest economical significance for the region. the parasite also infects sylvan (coatis and capybaras) and domestic (dogs) animals, respectively considered wild and domestic reservoirs of t. evansi. for a better understanding of the interaction of t. evansi with its rodent host, we evaluated the differences in the specific antibody level patterns and in the parasitic peptides recognition patterns of experimentally infected wistar rats. the rats experimentally infected with t. evansi isolates obtained from coatis, dogs and horses were submitted to indirect immunofluorescence test (igm e igg) and western blotting. the serological titers for igm and igg ranged between 1:40 and 1:160. the most recognized polypeptide profiles were in a range of 17 and 74 kda. our data suggest that the humoral immune response in wistar rats is not sufficient for granting an effective control of t. evansi infections.
METODOLOGIA FUZZY PARA AVALIA O DE ATIVOS INTANG VEIS EMPRESARIAIS
Pedro Paulo Silva Legey J?onior,Lamounier Erthal Villela,Jos?? Geraldo Pereira Barbosa
Revista de Administra??o FACES Journal , 2010,
Abstract: O objetivo desse artigo apresentar uma metodologia que permita quantificar os ativos intang -veis empresariais, a fim de contribuir nas decis μes sobre investimentos. Para tanto, a metodologia desenvolvida foi aplicada em grande empresa de navega § £o para medir seus indicadores de capital humano, estrutural e de relacionamento em sua rea de tecnologia da informa § £o. A L 3gica Fuzzy foi empregada para quantificar a percep § £o dos grupos sobre os indicadores e reduzir as incertezas oriundas da linguagem natural. Os resultados representaram um apoio para tomadas de decis £o sobre investimentos em ativos intang -veis. A aplica § £o peri 3dica da metodologia permitir avaliar os efeitos das decis μes dos gestores em outros momentos, contribuindo para o planejamento e controle gerencial, e colaborando para a valoriza § £o dos ativos intang -veis da empresa. Os resultados obtidos s £o espec -ficos da empresa estudada, mas validaram a aplica § £o e o uso da metodologia em outras empresas.
Trypanosoma cruzi in marsupial didelphids (Philander frenata and Didelhis marsupialis): differences in the humoral immune response in natural and experimental infections
Legey Ana Paula,Pinho Ana Paula,Xavier Samanta C.C.,Marchevsky Renato
Revista da Sociedade Brasileira de Medicina Tropical , 2003,
Abstract: Philander frenata and Didelphis marsupialis harbor parasitism by Trypanosoma cruzi without developing any apparent disease and on the contrary to D. marsupialis, P. frenata maintains parasitism by T. cruzi II subpopulations. Here we compared the humoral immune response of the two didelphids naturally and experimentally infected with T. cruzi II group, employing SDS-PAGE/Western blot techniques and by an Indirect immunofluorescence assay. We also studied the histopathological pattern of naturally and experimentally infected P. frenata with T. cruzi. P. frenata sera recognized more antigens than D. marsupialis, and the recognition pattern did not show any change over the course of the follow up of both didelphid species. Polypeptides of 66 and 90kDa were the most prominent antigens recognized by both species in the soluble and enriched membrane fractions. P. frenata recognized intensely also a 45kDa antigen. Our findings indicate that: 1) there were no quantitative or qualitative differences in the patent or subpatent phases in the recognition pattern of P. frenata; 2) the significant differences in the recognition pattern of parasitic antigens by P. frenata and D. marsupialis sera suggest that they probably "learned" to live in harmony with T. cruzi by different strategies; 3) although P. frenata do not display apparent disease, tissular lesions tended to be more severe than has been described in D. marsupialis; and 4) Both didelphids probably acquired infection by T. cruzi after their evolutionary divergence.
METODOLOGIA FUZZY PARA AVALIA O DE ATIVOS INTANGíVEIS EMPRESARIAIS
Pedro Paulo Silva Legey Júnior,Lamounier Erthal Villela,José Geraldo Pereira Barbosa
Revista de Administra??o FACES Journal , 2010,
Abstract: O objetivo desse artigo é apresentar uma metodologia que permita quantificar os ativos intangíveis empresariais, a fim de contribuir nas decis es sobre investimentos. Para tanto, a metodologia desenvolvida foi aplicada em grande empresa de navega o para medir seus indicadores de capital humano, estrutural e de relacionamento em sua área de tecnologia da informa o. A Lógica Fuzzy foi empregada para quantificar a percep o dos grupos sobre os indicadores e reduzir as incertezas oriundas da linguagem natural. Os resultados representaram um apoio para tomadas de decis o sobre investimentos em ativos intangíveis. A aplica o periódica da metodologia permitirá avaliar os efeitos das decis es dos gestores em outros momentos, contribuindo para o planejamento e controle gerencial, e colaborando para a valoriza o dos ativos intangíveis da empresa. Os resultados obtidos s o específicos da empresa estudada, mas validaram a aplica o e o uso da metodologia em outras empresas.
Humoral Immune Response Kinetics in Philander opossum and Didelphis marsupialis Infected and Immunized by Trypanosoma cruzi Employing an Immunofluorescence Antibody Test
Legey Ana Paula,Pinho Ana Paula S,Xavier Samanta C Chagas,Leon Leonor L
Memórias do Instituto Oswaldo Cruz , 1999,
Abstract: Philander opossum and Didelphis marsupialis considered the most ancient mammals and an evolutionary success, maintain parasitism by Trypanosoma cruzi without developing any apparent disease or important tissue lesion. In order to elucidate this well-balanced interaction, we decided to compare the humoral immune response kinetics of the two didelphids naturally and experimentally infected with T. cruzi and immunized by different schedules of parasite antigens, employing an indirect fluorescence antibody test (IFAT). Both didelphids responded with high serological titers to different immunization routes, while the earliest response occurred with the intradermic route. Serological titers of naturally infected P. opossum showed a significant individual variation, while those of D. marsupialis remained stable during the entire follow-up period. The serological titers of the experimentally infected animals varied according to the inoculated strain. Our data suggest that (1) IFAT was sensitive for follow-up of P. opossum in natural and experimental T. cruzi infections; (2) both P. opossum and D. marsupialis are able to mount an efficient humoral immune response as compared to placental mammals; (3) experimentally infected P. opossum and D. marsupialis present distinct patterns of infection, depending on the subpopulation of T. cruzi, (4) the differences observed in the humoral immune responses between P. opossum and D. marsupialis, probably, reflect distinct strategies selected by these animals during their coevolution with T. cruzi.
Specific antibody levels and antigenic recognition of Wistar rats inoculated with distinct isolates of Trypanosoma evansi
Queiroz Adriana O,Legey Ana P,Xavier Samanta CC,Jansen Ana M
Memórias do Instituto Oswaldo Cruz , 2001,
Abstract: "Mal de Cadeiras", an enzootic disease caused by Trypanosoma evansi, is one of the most important trypanosomiases in the Brazilian Pantanal region. The disease affects mainly horses, which are widely used in extensive cattle production, an activity of greatest economical significance for the region. The parasite also infects sylvan (coatis and capybaras) and domestic (dogs) animals, respectively considered wild and domestic reservoirs of T. evansi. For a better understanding of the interaction of T. evansi with its rodent host, we evaluated the differences in the specific antibody level patterns and in the parasitic peptides recognition patterns of experimentally infected Wistar rats. The rats experimentally infected with T. evansi isolates obtained from coatis, dogs and horses were submitted to indirect immunofluorescence test (IgM e IgG) and Western blotting. The serological titers for IgM and IgG ranged between 1:40 and 1:160. The most recognized polypeptide profiles were in a range of 17 and 74 kDa. Our data suggest that the humoral immune response in Wistar rats is not sufficient for granting an effective control of T. evansi infections.
Humoral Immune Response Kinetics in Philander opossum and Didelphis marsupialis Infected and Immunized by Trypanosoma cruzi Employing an Immunofluorescence Antibody Test
Legey, Ana Paula;Pinho, Ana Paula S;Xavier, Samanta C Chagas;Leon, Leonor L;Jansen, Ana Maria;
Memórias do Instituto Oswaldo Cruz , 1999, DOI: 10.1590/S0074-02761999000300016
Abstract: philander opossum and didelphis marsupialis considered the most ancient mammals and an evolutionary success, maintain parasitism by trypanosoma cruzi without developing any apparent disease or important tissue lesion. in order to elucidate this well-balanced interaction, we decided to compare the humoral immune response kinetics of the two didelphids naturally and experimentally infected with t. cruzi and immunized by different schedules of parasite antigens, employing an indirect fluorescence antibody test (ifat). both didelphids responded with high serological titers to different immunization routes, while the earliest response occurred with the intradermic route. serological titers of naturally infected p. opossum showed a significant individual variation, while those of d. marsupialis remained stable during the entire follow-up period. the serological titers of the experimentally infected animals varied according to the inoculated strain. our data suggest that (1) ifat was sensitive for follow-up of p. opossum in natural and experimental t. cruzi infections; (2) both p. opossum and d. marsupialis are able to mount an efficient humoral immune response as compared to placental mammals; (3) experimentally infected p. opossum and d. marsupialis present distinct patterns of infection, depending on the subpopulation of t. cruzi, (4) the differences observed in the humoral immune responses between p. opossum and d. marsupialis, probably, reflect distinct strategies selected by these animals during their coevolution with t. cruzi.
Family, Poverty and Inequalities in Latin America and the Caribbean  [PDF]
Cristina Gomes
Sociology Mind (SM) , 2013, DOI: 10.4236/sm.2013.31005
Abstract:

This article adopts the concept of development as freedom and the relationship between income and capabilities to analyze and compare macroeconomic, demographic and poverty trends and inequalities in Latin American and the Caribbean countries, and the responses from governments to promote the inclusion of the poorest and marginalized population groups in development and policies. Differences in population structures indicate that poverty and gender, generational and race inequalities fragment societies. Policies oriented to reduce poverty have been implemented with a set of combined programs such as cash transfers articulated with actions in nutrition, health, education, day-care programs for poor children, civil registration and other programs to promote poverty reduction and the conciliation of domestic and work life for poor women and social protection. Some good practices are discussed, particularly in Brazil and Mexico. During the last 15 years, the Conditioned Cash Transfers programs raised public support and political consensus, guaranteeing continuity in their implementation, development and integration with other social protection programs. Currently there are 18 countries implementing such programs, covering approximately 25 million households and over 133 million people, representing 19% of the Latin American and Caribbean. Policies to reduce poverty, in combination with income distribution and social protection in nutrition, health, education, civil registration and day-care for children, have contributed to human development, and also promoted internal market of consumers, even in rural areas, mobilizing local economies and promoting the return of investments to development. Despite the economic crisis in 2008-2009, Latin America had a relatively good performance in the world economy, demonstrating that social and economic

Family and women decide child nutrition—The role of human development, capabilities and lifestyles  [PDF]
Cristina Gomes
Health (Health) , 2013, DOI: 10.4236/health.2013.57153
Abstract:

In this article, capacities and freedom approach, as well as lifestyles are explored taking into account child nutrition, and other relevant dimensions of human life more than just economic and other elementary resources, and also social, cultural, psychological, values and freedom dimensions. Nourishment, health and survival are considered some of the elementary capabilities, and the concept of malnutrition, including under and over-nutrition, is discussed, based upon the comparison of data on food production and distribution from the macro level context, as well as from the family and individual levels included anthropometrical measurements. The advantages and limits of different kinds of measurements are discussed, suggesting more complex approaches, based also upon family and gender equality. The double burden of malnutrition, under and over-nourishment of children is highlighted as a public health issue to be resolved by adequate policies and considering the role of female empowerment, nutrition-knowledge and education as relevant keys to achieve equality in family food and resource distribution, healthy lifestyles and human development.

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