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Search Results: 1 - 10 of 185 matches for " CN Muthaura "
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In vitro anti-viral activity of aqueous extracts of Kenyan Carissa edulis Prunus africana and Melia azedarach against human cytomegalovirus.
FM Tolo, GM Rukunga, FW Muli, J Ochora, Y Eizuru, CN Muthaura, CW Kimani, GM Mungai, MW Kofi-Tsekpo
African Journal of Health Sciences , 2007,
Abstract: The aqueous extracts of three medicinal plants, Carissa edulis (Forssk.) Vahl (Apocynaceae), Prunus africana (Hook.f.) Kalkm (Rosaceae) and Melia azedarach L. (Meliaceae) have shown significant reduction in the replication of human cytomegalovirus (HCMV) in human embryonic lung (HEL) fibroblasts cells in vitro. Using the plaque inhibition assay for the determination of anti-viral activity, the HEL fibroblast cells cultured in 24 well plates were infected with 1 x 102 PFU 91S HCMV and treated with various concentrations of the extracts. The plaques formed were counted after 7 days incubation at 370C in 5% CO2 and the percent plaques inhibited were calculated against infected untreated control. The effective concentrations inhibiting plaque formation by 50% (EC50) was found between 40 to 80 μg/ml for all the extracts. The cell cytotoxic concentrations (CC50) for each of the three extracts, by the trypan blue exclusion test, gave a safe therapeutic index. These results have demonstrated the potential anti-viral activities of the extracts of the three medicinal plants at non-cytotoxic concentrations. African Journal of Health Sciences Vol. 14 (3-4) 2007: pp. 143-148
The Perceptions of the Preparedness of Medical Graduates to Take on Internship Responsibilities in Low Resource Hospitals in Kenya
Patricia N. Muthaura,Tashmin K. Khamis
Higher Education Studies , 2013, DOI: 10.5539/hes.v3n1p115
Abstract: The Aga Khan University is developing an Undergraduate Medical Education (UGME) curriculum for implementation in East Africa in 2016, which aims to serve the health needs of the populations there. Pilot focus group discussions of recent interns were conducted at the Aga Khan University Hospital, Nairobi to find out: (1) If Kenyan medical students are adequately prepared for their roles as interns in low resource hospitals upon graduation from medical schools; (2) The likely clinical conditions that interns will face in low resource hospitals in Kenya; and (3) How might the UGME curriculum best prepare interns for their roles in low resource hospital settings? Through focus group discussions, current and recent interns expressed feeling ill prepared for working in low resource settings, unequipped with the clinical skills for the tasks and procedures expected of an intern ,in adequately exposed to obstetrics, paediatrics, emergency medicine and lacking in resuscitation training. These findings will inform the development of the UGME curriculum to ensure learning outcomes that meet stakeholder requirements.
FOR DEBATE Policy of Exclusive Breastfeeding for Six Months: A re-examination
CN. Ogbu
Nigerian Journal of Paediatrics , 2001,
Abstract: ,br>While it is well accepted that breast-feeding is natural and that human breast milk is a unique and appropriate food for full term healthy neonates, controversy continues to dog the recommendation that babies should be exclusively breast-fed for the first six months of life. In this paper, evidence is presented to show that while human milk alone can provide adequate macro- and micronutrients for normal growth and development of full term infants for the first 3-4 months of life, it is inadequate for older infants. Growth faltering whose effects on the rapidly growing brain is unknown, nutritional rickets, iron deficiency anaemia and zinc deficiency have been reported in infants exclusively breast-fed beyond four months of age. It is therefore, strongly recommended that exclusive breast-feeding should not last beyond four months of age, while breast-feuding could continue for as long as it is feasible and practicable for the mother. This should ensure normal growth and development of the infant who would also reap other benefits of breast milk and breast-feeding. Nigerian Journal of Paediatrics 2001; 28:53. pp 53-60
Antimicrobial susceptibility pattern of klebsiella species from Ebonyi State University Teaching Hospital Abakaliki, Nigeria
CN Akujobi
Nigerian Journal of Clinical Practice , 2005,
Abstract: Klesiella specie isolated from clinical specimens from Ebonyi State University Teaching Hospital ( EBSUTH), Abakakliki were studied to determine the antimicrobial susceptibility patter.Between January, 2003 and September 2004 a totaql of 3,600 specimens processed in the routine Medical Microbiology laboratory of EBSUTH, of which 245(6.8%) yielded Klebsilla species, with 84 from out – patients and 161 from in – patients The number of isolates from various samples were:” Urine 126, Sputum 37 Edocervical swab 13, Aspirates 8, High Vaginal Swab 7, Blood 3,Eye Swab, Ear Swab and Cerebrospinal fluid were 2 samples each. Organisms were identified b y the conventional methods. Antimicrobial susceptibility was done by the disk diffusion methods. The antimicrobial disk used include: Ceftazidime, Cefurxime, Cefotaxine, Augmentin, Pefloxacin (30ug), Doxycyline (25ug) Genticin (10 ug) Cigprofloacin and Ofloxacin (5ug) each and Erythromycin (15ug) all were Oxoid products. Results were interpreted according to NCCLS criteria. Klebsilla species were isolated most from urine specimens (51.4%) followed by wound swsabs (18.4%) Antimicrobial susceptibility to various groups drugs used was generally poor. The most sensitive antimicrobial was Cipprofoxacin with 121(49.4%) isolates susceptible to it, followed by Genetamicin with 95(38.8%) than Ceftazidime with 90(36.7%). Seventeen isolates were muti resistant to all the antimicrobial agents used. The result of this study will help in the empirc theraopy of infection csused by Klebsella species in Ebonyi State University Teaching Hospital, Abakaliki, Nigeria but continuous surverillance of antimicrobial resistance of the organnisn is very necessary in the formulation of a sound a antibiotic policy in the hospital
Trade Unionism, Collective Bargaining and Nation Building: The Nigerian Experience
CN Okolie
OGIRISI: a New Journal of African Studies , 2010,
Abstract: No
Women Participation In Agricutural Decision-Making In Aguata Local Governmmment Area, Anambra State
CN Okafor
Journal of Agricultural Extension , 2008,
Abstract: A study involving 120 women respondents investigated the level of women farmer’s participation in Agricultural decision-making in Aguata Local Government Area (LGA) of Anambra State. Primary data were collected using structured questionnaire and interview schedule. The data were analyzed using descriptive statistics. Results showed that majority of the women farmers (80%) had between 10 to 20 years farming experience which helped them in making rational choice and decisions. About 75% of the women were full-time farmers who have contact with extension agents and belonged to Cooperative Societies. Results also showed that there was a low level (100%) of women farmers’ participation in taking major decision in group agricultural projects involving men. However 60% are involved in crucial farm decisions at family level. It is recommended that involving women farmers in decision-making at all stages of group and family agricultural projects should be a policy in the LGA and a road map to achieving sustainable agricultural development. Policy makers and planners therefore, need to acknowledge that farmers and other groups in the agricultural production chain can only work effectively within the framework of the policies that they put in place.
Chemotherapy and Targeted therapy in Hormone Refractory Prostate Cancer (HRPC)
Sternberg CN
Journal für Urologie und Urogyn?kologie , 2007,
Lesiones dermatológicas del síndrome de Apert: A propósito de un caso clínico
Chirino,CN; Schwartz,RJ;
Revista argentina de dermatolog?-a , 2010,
Abstract: we report a woman 26 years old with apert syndrome (as). she has acneiform lesions from thirteen years ago, characterized by resistence to treatment and a remarkable tendency to recur. as this picture is really weird, we consider it timely to review literature about dermatologic disease associated with it.
Flood Characteristics and Management Adaptations in Parts of the Imo River System
MN Ezemonye, CN Emeribe
Ethiopian Journal of Environmental Studies and Management , 2011,
Abstract: This paper examined the physical characteristics of floods and management adaptations to flood hazards in the Imo River basin. From the study, it was determined that the pre and post flood disaster management is a yearly event. The extent and time of commencement usually differs in each flood season, being between July, August and September when rainfall is at its peak. From the study, it was observed that flood duration in the sampled communities last for as much as three to four months. The velocity of the floodwaters under peak discharge usually between August and September was observed to be sluggish, while being faster during recession in mid-October. An investigation of human adaptation to flooding in affected communities indicated that up to 70% of the inhabitants have derived ways of managing their flood disasters on short term basis. These adaptation methods include emergency evacuation and rescheduling of activities, bearing flood losses and land use changes. It is recommended flood forecasting and warming systems be introduced. Engineering control of the major tributaries of the Imo River system is required to reduce impact of flooding on the settlements, while land use zoning will serve as an effective adaptation and disaster management option in the study area.
Naphthalene and pyrene degradation in contaminated soil as a function of the variation of particle size and percent organic matter
CN Owabor, OF Ogunbor
African Journal of Biotechnology , 2007,
Abstract: The effect of soil particle size distribution and percent organic matter on the degradation rate of naphthalene and pyrene in a water medium of 7.05 ml/min at 27 ± 2oC in a soil reactor was studied. Analysis of the pattern of disappearance of these polycyclic aromatic hydrocarbons (PAHs) using various particle sizes showed a rapid decline of concentration of the chemicals during initial stages of bioremediation treatment, followed by a slow reduction rate. The extent of naphthalene and pyrene removal and final concentrations for the period under study differed among the different soil particle sizes. Results show that from an initial 100 mg/l, the concentration of both naphthalene and pyrene decreased in the following sequence clay > silt > fine sand > coarse sand. The degradation of the two PAHs was significantly enhanced by the addition of organic matter to the bulk composite soil. The specific reaction rate constant k was found to increase with decreasing particle size and increase with increasing % organic matter. For both PAHs, coarse sand had the lowest rate constant while clay had the highest. This implies that degradation was faster in the clay fraction than in the other soil fractions. The correlation coefficients obtained using linear regression method was between 0.734 and 0.996 indicating the reliability of the experimental data.
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